Rakesh Sindhi

Summary

Affiliation: Children's Hospital of Pittsburgh
Country: USA

Publications

  1. doi request reprint Allospecific CD154 + T-cytotoxic memory cells as potential surrogate for rejection risk in pediatric intestine transplantation
    Rakesh Sindhi
    Hillman Center for Pediatric Transplantation, Children s Hospital of Pittsburgh of the University of Pittsburgh Medical Center, Pittsburgh, PA 15224, USA
    Pediatr Transplant 16:83-91. 2012
  2. ncbi request reprint Reduced immunosuppression in pediatric liver-intestine transplant recipients with CD8+CD28- T-suppressor cells
    Rakesh Sindhi
    Division of Transplantation, University of Pittsburgh, Pittsburgh, PA 15213, USA
    Hum Immunol 66:252-7. 2005
  3. pmc Genetic variants in major histocompatibility complex-linked genes associate with pediatric liver transplant rejection
    Rakesh Sindhi
    Hillman Center for Pediatric Transplantation, Children s Hospital of Pittsburgh, Pittsburgh, Pennsylvania 15213, USA
    Gastroenterology 135:830-9, 839.e1-10. 2008
  4. ncbi request reprint Replacing calcineurin inhibitors with mTOR inhibitors in children
    Rakesh Sindhi
    Children s Hospital of Pittsburgh and the University of Pittsburgh, Pittsburgh, PA 15217, USA
    Pediatr Transplant 9:391-7. 2005
  5. doi request reprint Immune monitoring in small bowel transplantation
    Rakesh Sindhi
    Hillman Center for Pediatric Transplantation, Children s Hospital of Pittsburgh of UPMC, Pittsburgh, Pennsylvania, USA
    Curr Opin Organ Transplant 15:349-56. 2010
  6. ncbi request reprint Enhanced donor-specific alloreactivity occurs independently of immunosuppression in children with early liver rejection
    Rakesh Sindhi
    Thomas E Starzl Transplantation Institute, University of Pittsburgh, Pittsburgh, PA, USA
    Am J Transplant 5:96-102. 2005
  7. ncbi request reprint Multiparametric effect: concentration analyses
    Rakesh Sindhi
    Department of Pediatric Transplantation, Children s Hospital of Pittsburgh, and the University of Pittsburgh, Pittsburgh, PA 15213, USA
    Front Biosci 9:1218-21. 2004
  8. doi request reprint Cellular alloresponses for rejection-risk assessment after pediatric transplantation
    Rakesh Sindhi
    Children s Hospital of Pittsburgh of UPMC, University of Pittsburgh, Pittsburgh, PA, USA
    Curr Opin Organ Transplant 16:515-21. 2011
  9. doi request reprint Lymphoproliferative disorders and de novo malignancies in intestinal and multivisceral recipients: improved outcomes with new outlooks
    Kareem M Abu-Elmagd
    Department of Surgery, Thomas E Starzl Transplant Institute, University of Pittsburgh, Pittsburgh, PA 15213, USA
    Transplantation 88:926-34. 2009
  10. doi request reprint Lymphocyte subset reconstitution patterns in children with small bowel transplantation induced with steroid-free rabbit anti-human thymocyte globulin
    Anjan J Talukdar
    Pediatric Transplantation Laboratory, Hillman Center for Pediatric Transplantation, Children s Hospital of Pittsburgh, PA, USA
    Pediatr Transplant 13:353-9. 2009

Collaborators

Detail Information

Publications61

  1. doi request reprint Allospecific CD154 + T-cytotoxic memory cells as potential surrogate for rejection risk in pediatric intestine transplantation
    Rakesh Sindhi
    Hillman Center for Pediatric Transplantation, Children s Hospital of Pittsburgh of the University of Pittsburgh Medical Center, Pittsburgh, PA 15224, USA
    Pediatr Transplant 16:83-91. 2012
    ..rATG. Rejection-risk assessment with CD154 + TcM may enable informed immunosuppression minimization, and preliminary efficacy comparisons in pediatric ITx...
  2. ncbi request reprint Reduced immunosuppression in pediatric liver-intestine transplant recipients with CD8+CD28- T-suppressor cells
    Rakesh Sindhi
    Division of Transplantation, University of Pittsburgh, Pittsburgh, PA 15213, USA
    Hum Immunol 66:252-7. 2005
    ..Such assays may also permit safe evaluation of prospective immunosuppression withdrawal strategies...
  3. pmc Genetic variants in major histocompatibility complex-linked genes associate with pediatric liver transplant rejection
    Rakesh Sindhi
    Hillman Center for Pediatric Transplantation, Children s Hospital of Pittsburgh, Pittsburgh, Pennsylvania 15213, USA
    Gastroenterology 135:830-9, 839.e1-10. 2008
    ....
  4. ncbi request reprint Replacing calcineurin inhibitors with mTOR inhibitors in children
    Rakesh Sindhi
    Children s Hospital of Pittsburgh and the University of Pittsburgh, Pittsburgh, PA 15217, USA
    Pediatr Transplant 9:391-7. 2005
    ..Improvement in renal function and hypertension management, and absence of sirolimus-related adverse events argue for prospective evaluation of regimens in which mTOR inhibitors are used without calcineurin inhibitors in children...
  5. doi request reprint Immune monitoring in small bowel transplantation
    Rakesh Sindhi
    Hillman Center for Pediatric Transplantation, Children s Hospital of Pittsburgh of UPMC, Pittsburgh, Pennsylvania, USA
    Curr Opin Organ Transplant 15:349-56. 2010
    ..Immune monitoring is needed in small bowel transplantation (SBTx) because of a high incidence of rejection and graft loss, and life-threatening complications of high-dose prophylactic immunosuppression...
  6. ncbi request reprint Enhanced donor-specific alloreactivity occurs independently of immunosuppression in children with early liver rejection
    Rakesh Sindhi
    Thomas E Starzl Transplantation Institute, University of Pittsburgh, Pittsburgh, PA, USA
    Am J Transplant 5:96-102. 2005
    ..To determine whether early acute cellular rejection (ACR) is associated with sub-optimal immunosuppression in children with liver transplants (LTx)...
  7. ncbi request reprint Multiparametric effect: concentration analyses
    Rakesh Sindhi
    Department of Pediatric Transplantation, Children s Hospital of Pittsburgh, and the University of Pittsburgh, Pittsburgh, PA 15213, USA
    Front Biosci 9:1218-21. 2004
    ..The potential implications of these models crystallize the clinical challenges confronting practitioners of clinical, post-transplant immunosuppression...
  8. doi request reprint Cellular alloresponses for rejection-risk assessment after pediatric transplantation
    Rakesh Sindhi
    Children s Hospital of Pittsburgh of UPMC, University of Pittsburgh, Pittsburgh, PA, USA
    Curr Opin Organ Transplant 16:515-21. 2011
    ..We review the use of mixed lymphocyte coculture-based assays that measure cellular alloresponses, for measurement of the risk of ACR after liver, intestine, and kidney transplantation...
  9. doi request reprint Lymphoproliferative disorders and de novo malignancies in intestinal and multivisceral recipients: improved outcomes with new outlooks
    Kareem M Abu-Elmagd
    Department of Surgery, Thomas E Starzl Transplant Institute, University of Pittsburgh, Pittsburgh, PA 15213, USA
    Transplantation 88:926-34. 2009
    ..To improve outcome, innovative management and immunosuppressant strategies were sequentially evolved...
  10. doi request reprint Lymphocyte subset reconstitution patterns in children with small bowel transplantation induced with steroid-free rabbit anti-human thymocyte globulin
    Anjan J Talukdar
    Pediatric Transplantation Laboratory, Hillman Center for Pediatric Transplantation, Children s Hospital of Pittsburgh, PA, USA
    Pediatr Transplant 13:353-9. 2009
    ..Rejection-prone children also demonstrate significantly higher counts of total lymphocytes, Tc and NK cells prior to SBTx, and may illustrate one basis for enhanced baseline immunocompetence...
  11. doi request reprint Evolution of the immunosuppressive strategies for the intestinal and multivisceral recipients with special reference to allograft immunity and achievement of partial tolerance
    Kareem M Abu-Elmagd
    Intestinal Rehabilitation and Transplantation Center, Thomas E Starzl Transplantation Institute, University of Pittsburgh Medical Center, PA, USA
    Transpl Int 22:96-109. 2009
    ....
  12. pmc Elevated myeloid: plasmacytoid dendritic cell ratio associates with late, but not early, liver rejection in children induced with rabbit anti-human thymocyte globulin
    Ankit Gupta
    Hillman Center for Pediatric Transplantation, Children s Hospital of Pittsburgh, University of Pittsburgh, Pittsburgh, PA 15217, USA
    Transplantation 88:589-94. 2009
    ..Dendritic cells (DC) play an important role in the induction and regulation of immune responses...
  13. doi request reprint Five hundred intestinal and multivisceral transplantations at a single center: major advances with new challenges
    Kareem M Abu-Elmagd
    Thomas E Starzl Transplantation Institute, University of Pittsburgh Medical Center, Pittsburgh, PA 15213, USA
    Ann Surg 250:567-81. 2009
    ..To assess the evolution of visceral transplantation in the milieu of surgical technical modifications, new immunosuppressive protocols, and other management strategies...
  14. pmc Intestinal transplantation under tacrolimus monotherapy after perioperative lymphoid depletion with rabbit anti-thymocyte globulin (thymoglobulin)
    Jorge Reyes
    Children s Hospital of Pittsburgh, University of Pittsburgh Medical Center, Thomas E Starzl Transplantation Institute, USA
    Am J Transplant 5:1430-6. 2005
    ..This strategy of immunosuppression minimized maintenance TAC exposure, facilitated the long-term control of rejection, decreased the incidence of opportunistic infections, and resulted in a high rate of patient and graft survival...
  15. pmc Proliferative alloresponse of T-cytotoxic cells identifies rejection-prone children with steroid-free liver transplantation
    Chethan Ashokkumar
    Hillman Center for Pediatric Transplantation, Children s Hospital of Pittsburgh, Pittsburgh, PA, USA
    Liver Transpl 15:978-85. 2009
    ..630, P = 0.007). In conclusion, proliferative alloresponses of Tc cells can identify rejection-prone children receiving LTx. Liver Transpl 15:978-985, 2009. (c) 2009 AASLD...
  16. doi request reprint NOD2 gene polymorphism rs2066844 associates with need for combined liver-intestine transplantation in children with short-gut syndrome
    Mylarappa Ningappa
    Hillman Center for Pediatric Transplantation, University of Pittsburgh, Pittsburgh, Pennsylvania 15224, USA
    Am J Gastroenterol 106:157-65. 2011
    ....
  17. doi request reprint Allospecific CD154+ B cells associate with intestine allograft rejection in children
    Chethan Ashokkumar
    Department of Surgery, Children s Hospital of Pittsburgh, University of Pittsburgh, Pittsburgh, PA, USA
    Transplantation 90:1226-31. 2010
    ....
  18. ncbi request reprint Proliferative alloresponse of T cytotoxic cells identifies rejection-prone children with small bowel transplantation
    Chethan Ashokkumar
    Hillman Center for Pediatric Transplantation, Children s Hospital of Pittsburgh, University of Pittsburgh, Pittsburgh, PA 15213, USA
    Transplantation 89:1371-7. 2010
    ..More than 60% children with small bowel transplantation (SBTx) experience acute cellular rejection...
  19. doi request reprint Mucosal plasma cell barrier disruption during intestine transplant rejection
    Mylarappa Ningappa
    Hillman Center for Pediatric Transplantation, Children s Hospital of Pittsburgh of the University of Pittsburgh Medical Center UPMC, Pittsburgh, PA, USA
    Transplantation 94:1236-42. 2012
    ..Intestinal allograft mucosa undergoes repopulation with host immunocytes. However, critical changes within key immunocyte subsets are not known...
  20. doi request reprint Long-term survival, nutritional autonomy, and quality of life after intestinal and multivisceral transplantation
    Kareem M Abu-Elmagd
    Thomas E Starzl Transplantation Institute, University of Pittsburgh Medical Center, Pittsburgh, PA 15213, USA
    Ann Surg 256:494-508. 2012
    ..To assess long-term survival, graft function, and health-related quality of life (QOL) after visceral transplantation...
  21. ncbi request reprint Allospecific CD154+ T cells identify rejection-prone recipients after pediatric small-bowel transplantation
    Chethan Ashokkumar
    Hillman Center for Pediatric Transplantation, Children s Hospital of Pittsburgh, Pittsburgh, PA 15213, USA
    Surgery 146:166-73. 2009
    ..Allospecific CD154+ T cells predict liver ACR in children in a novel, 16-hour mixed leukocyte response (MLR) assay, but remain untested in SBTx...
  22. ncbi request reprint Evolutionary experience with immunosuppression in pediatric intestinal transplantation
    Geoffrey J Bond
    Thomas E Starzl Transplantation Institute, Children s Hospital of Pittsburgh, University of Pittsburgh School of Medicine, Pittsburgh, PA 15213, USA
    J Pediatr Surg 40:274-9; discussion 279-80. 2005
    ..The authors review their evolutionary experience with intestinal transplantation, particularly relating changes in immunosuppression protocols to improved outcomes...
  23. doi request reprint Increased monocyte expression of sialoadhesin during acute cellular rejection and other enteritides after intestine transplantation in children
    Chethan Ashokkumar
    Hillman Center for Pediatric Transplantation, Children s Hospital of Pittsburgh, and the University of Pittsburgh, Pittsburgh, PA, USA
    Transplantation 93:561-4. 2012
    ..Monocyte-derived macrophages prime acute cellular rejection after intestine transplantation (ITx).The purpose of this study was to evaluate whether CD169-expressing activated monocytes associate with or predict ITx rejection...
  24. doi request reprint Pediatric small bowel transplantation
    Navdeep Nayyar
    Hillman Center for Pediatric Transplantation, Children s Hospital of Pittsburgh, University of Pittsburgh, Pittsburgh, Pennsylvania, USA
    Semin Pediatr Surg 19:68-77. 2010
    ..Finally, inflammatory mechanisms, which predispose the highly immunogenic small bowel allograft to a protracted risk of resistant rejection must be elucidated, in order to ensure durable success...
  25. doi request reprint Elevated myeloid: plasmacytoid dendritic cell ratio associates with early acute cellular rejection in pediatric small bowel transplantation
    Ankit Gupta
    Hillman Center for Pediatric Transplantation, Children s Hospital of Pittsburgh, University of Pittsburgh, Pittsburgh, PA 15213, USA
    Transplantation 89:55-60. 2010
    ..Dendritic cells (DCs) are potent antigen-presenting cells, modulate immune responses to gut microbes, and may serve as markers of rejection-prone small bowel transplantation (SBTx)...
  26. doi request reprint Modified "liver-sparing" multivisceral transplant with preserved native spleen, pancreas, and duodenum: technique and long-term outcome
    Ruy J Cruz
    Thomas E Starzl Transplantation Institute, University of Pittsburgh Medical Center, 3459 Fifth Avenue, MUH 7 South, Pittsburgh, PA 15213, USA
    J Gastrointest Surg 14:1709-21. 2010
    ..Modification of the originally described multivisceral transplant operation was introduced at our institution 17 years ago. Donor liver was spared, and native spleen along with pancreaticoduodenal complex was preserved...
  27. doi request reprint Analysis of national and single-center incidence and survival after liver transplantation for hepatoblastoma: new trends and future opportunities
    Ruy J Cruz
    Starzl Transplantation Institute, University of Pittsburgh Medical Center, Pittsburgh, PA, USA
    Surgery 153:150-9. 2013
    ..Liver transplantation (LTx) for hepatoblastoma appears to be increasing. Favorable tumor histology is increasingly linked to survival after surgical resection and could also determine posttransplantation outcomes...
  28. doi request reprint Allospecific CD154+ T-cytotoxic memory cells identify recipients experiencing acute cellular rejection after renal transplantation
    Chethan Ashokkumar
    Hillman Center for Pediatric Transplantation, Children s Hospital of Pittsburgh of UPMC, University of Pittsburgh, Pittsburgh, PA, USA
    Transplantation 92:433-8. 2011
    ....
  29. ncbi request reprint Individualizing combination of two antiproliferative immunosuppressants with pharmacodynamic modeling of stimulated lymphocyte responses
    Vishal Berry
    Division of Transplantation, Department of Surgery, University of Pittsburgh, Pittsburgh, PA 15217, USA
    Cytometry A 69:95-103. 2006
    ..However, titration of such combinations to individual needs is not understood...
  30. pmc Increased expression of peripheral blood leukocyte genes implicate CD14+ tissue macrophages in cellular intestine allograft rejection
    Chethan Ashokkumar
    Hillman Center for Pediatric Transplantation, Children s Hospital of Pittsburgh of University of Pennsylvania Medical Center, Pittsburgh, Pennsylvania, USA
    Am J Pathol 179:1929-38. 2011
    ..CCL5 gene up-regulation and CD14(+) macrophages likely prime cellular ITx rejection. Infiltration of reperfused intestine allografts with CD14(+) macrophages may predict rejection events...
  31. doi request reprint One thousand consecutive primary liver transplants under tacrolimus immunosuppression: a 17- to 20-year longitudinal follow-up
    Ashokkumar Jain
    Division of Abdominal Organ Transplantation, Department of Surgery, Temple University Hospital, Philadelphia, PA, USA
    Transplantation 91:1025-30. 2011
    ..Tacrolimus has proven to be a potent immunosuppressive agent in orthotopic liver transplantation (OLT). The aim of this study is to examine its long-term efficacy and safety...
  32. doi request reprint Pediatric intestinal retransplantation: techniques, management, and outcomes
    George V Mazariegos
    Hillman Center for Pediatric Transplantation, Children s Hospital of Pittsburgh, Pittsburgh, PA 15213, USA
    Transplantation 86:1777-82. 2008
    ..Intestinal retransplantation (Re-ITx) has historically been associated with high morbidity and mortality...
  33. ncbi request reprint Carcinoma of donor origin after liver-intestine transplantation in a child
    Joao Seda Neto
    Thomas E Starzl Transplantation Institute, Pittsburgh, PA, USA
    Pediatr Transplant 9:244-8. 2005
    ..The mechanism of such regression of tumor may be related to restitution of immunologic competence, but is yet to be determined...
  34. ncbi request reprint Persistent donor-specific alloreactivity may portend delayed liver rejection during drug minimization in children
    Nandita Khera
    University of Pittsburgh, Children s Hospital of Pittsburgh, 3705 Fifth Avenue, Pittsburgh, PA 15217, USA
    Front Biosci 12:660-3. 2007
    ..0048), and 3. experienced greater ACR incidence during minimization of immunosuppression (35% versus 6%, p=0.032). Serial monitoring of immunoreactivity may increase the safety with which immunosuppression is minimized in pediatric LTx...
  35. ncbi request reprint Immunosuppressant strategies for intestinal transplantation: a review of a tolerogenic regimen
    Bridget Flynn
    University of Pittsburgh Medical Center, Pittsburgh, PA, USA
    Prog Transplant 15:60-4. 2005
    ..Subsequently, the long-term complications of immunosuppression are significantly reduced with achievement of better long-term survival, and an overall improvement in the quality of life...
  36. pmc Lymphocyte subset reconstitution in pediatric liver recipients induced with steroid-free rabbit anti-human thymocyte globulin
    Anjan Talukdar
    Pediatric Transplantation Laboratory, Hillman Center for Pediatric Transplantation, Childrens Hospital of Pgh and the University of Pittsburgh, Pittsburgh, PA, USA
    Pediatr Transplant 12:804-8. 2008
    ..Rejection-prone children demonstrate significantly higher counts of lymphocytes and all subsets prior to liver transplantation, and may exemplify one basis for enhanced baseline immunocompetence...
  37. ncbi request reprint Lymphocyte subsets may discern treatment effects in children and young adults with post-transplant lymphoproliferative disorder
    Ryan LeVasseur
    Department of Pediatric Transplantation, Children s Hospital, University of Pittsburgh, Pittsburgh, PA 15217, USA
    Pediatr Transplant 7:370-5. 2003
    ..Clinical remission with rituximab is accompanied by B-cell depletion. Serial monitoring of PLS from the time of diagnosis of PTLD will be necessary to confirm these observations...
  38. ncbi request reprint Sclerosing peritonitis after intestinal transplantation in children
    Camila Macedo
    Thomas E Starzl Transplantation Institute, Pittsburgh, PA, USA
    Pediatr Transplant 9:187-91. 2005
    ..SP after ITx may be a different manifestation of long-term intestine allograft degeneration. Surgical resection appears to offer palliation...
  39. ncbi request reprint Graft versus host disease in intestinal transplantation
    George V Mazariegos
    Children s Hospital of Pittsburgh, Thomas E Starzl Transplantation Institute, University of Pittsburgh School of Medicine, Pittsburgh, PA, USA
    Am J Transplant 4:1459-65. 2004
    ..5% (8/122) in children and 4.7% (6/128) in adults. Successful clinical management requires a high index of suspicion to minimize morbidity and mortality. Diagnostic and treatment strategies based on this experience are proposed...
  40. ncbi request reprint Causes of mortality beyond 1 year after primary pediatric liver transplant under tacrolimus
    Jonathan A Fridell
    Department of Surgery, Children s Hospital of Pittsburgh, and Thomas E Starzl Transplantation Institute, University of Pittsburgh Medical Center, Pittsburgh, PA 15213, USA
    Transplantation 74:1721-4. 2002
    ..Most posttransplant deaths occur early and are related to surgical complications or recipient status at the time of transplantation. The causes of mortality beyond the first year have not been well described...
  41. ncbi request reprint Preliminary immunosuppression withdrawal strategies with sirolimus in children with liver transplants
    Rakesh Sindhi
    Pediatric Transplantation, Children s Hospital of Pittsburgh, 3705 Fifth Avenue, Pittsburgh, PA 15217, USA
    Transplant Proc 34:1972-3. 2002
  42. doi request reprint Intestinal transplantation in children: a review of immunotherapy regimens
    Navdeep S Nayyar
    Hillman Center for Pediatric Transplantation, Childrens Hospital of Pittsburgh of UPMC, Pittsburgh, Pennsylvania 15224, USA
    Paediatr Drugs 13:149-59. 2011
    ..Optimization of post-transplant immunosuppression strategies to reduce adverse effects while minimizing acute and chronic graft rejection is a strong clinical and research focus...
  43. doi request reprint Right diaphragmatic hernia after liver transplant in pediatrics: a case report and review of the literature
    Hwai Ding Lam
    Starzl Transplantation Institute, Hillman Center for Pediatric Transplantation, Children s Hospital of Pittsburgh of UPMC, Pittsburgh, PA 15224, USA
    Pediatr Transplant 17:E77-80. 2013
    ..For pediatric patients with otherwise unexplained respiratory or gastrointestinal symptoms after a left lateral segment liver transplant, right-sided diaphragmatic hernias should always be high in the differential diagnosis...
  44. doi request reprint Current status of pediatric intestinal failure, rehabilitation, and transplantation: summary of a colloquium
    George V Mazariegos
    Department of Pediatric Transplantation, Children s Hospital of Pittsburgh of UPMC, University of Pittsburgh Medical Center, Pittsburgh, PA 15224, USA
    Transplantation 92:1173-80. 2011
    ..Areas of opportunity such as increased donor recovery, improvement of long-term transplant outcomes, optimization of immune monitoring, and quality-of-life outcomes were reviewed...
  45. ncbi request reprint Pharmacokinetics of sirolimus and tacrolimus in pediatric transplant patients
    Marika Schubert
    Thomas E Starzl Transplantation Institute of the Children s Hospital of Pittsburgh, Pittsburgh, PA, USA
    Am J Transplant 4:767-73. 2004
    ..During conversion of subjects from TAC to combined TAC and SRL, aggressive therapeutic drug monitoring must be used to individualize therapy and avoid serous adverse events...
  46. ncbi request reprint Liver and intestinal transplantation in a child with cystic fibrosis: a case report
    Jonathan A Fridell
    Children s Hospital of Pittsburgh, Department of Pediatric Transplantation, Thomas E Starzl Transplantation Institute, Pittsburgh, PA 15213, USA
    Pediatr Transplant 7:240-2. 2003
    ..Extrapolating from the excellent experience of liver transplantation in children with CF, early liver and small intestinal multivisceral transplantation, if indicated, can be performed safely in children with CF...
  47. ncbi request reprint Tufting enteropathy revisited: the utility of MOC31 (EpCAM) immunohistochemistry in diagnosis
    Sarangarajan Ranganathan
    Department of Pathology Hillman Center for Transplantation, Children s Hospital of Pittsburgh of UPMC, University of Pittsburgh School of Medicine, Pittsburgh, PA
    Am J Surg Pathol 38:265-72. 2014
    ..MOC31 is a diagnostic stain for TE and should be included in the panel in any case of prolonged diarrhea in children to exclude this possibility...
  48. ncbi request reprint Modeling individual variation in biomarker response to combination immunosuppression with stimulated lymphocyte responses-potential clinical implications
    Rakesh Sindhi
    Children s Hospital of Pittsburgh, Room 4A 459, 3705 Fifth Avenue, PA 15213, USA
    J Immunol Methods 272:257-72. 2003
    ..This is not known for multiple-agent combinations...
  49. ncbi request reprint Transient posttransplant graft-versus-host lymphadenopathy
    Laurentia Nodit
    Department of Pathology, Children s Hospital of Pittsburgh and the University of Pittsburgh School of Medicine, 3705 Fifth Avenue, Pittsburgh, PA 15213, USA
    Pediatr Dev Pathol 7:533-7. 2004
    ..Circulating donor cells fell to 2.5% by day 62, and the child has been rejection free on low-dose immunosuppression...
  50. ncbi request reprint Liver transplantation in children with cystic fibrosis: a long-term longitudinal review of a single center's experience
    Jonathan A Fridell
    Department of Pediatric Transplantation, Thomas E Starzl Transplantation Institute, Children s Hospital of Pittsburgh, Pittsburgh, PA 15213, USA
    J Pediatr Surg 38:1152-6. 2003
    ..Of these, end-stage liver disease is a significant cause of morbidity and mortality with liver transplantation being the only effective therapy...
  51. ncbi request reprint Clinical tolerance following liver transplantation: long term results and future prospects
    George V Mazariegos
    Hillman Center for Pediatric Transplantation, Children s Hospital of Pittsburgh, University of Pittsburgh Medical Center, Pittsburgh, PA 15213, USA
    Transpl Immunol 17:114-9. 2007
    ....
  52. doi request reprint Review of outcomes of primary liver cancers in children: our institutional experience with resection and transplantation
    Marcus M Malek
    Division of Pediatric General and Thoracic Surgery, University of Pittsburgh Medical Center, Children s Hospital of UPMC, Pittsburgh, PA 15224, USA
    Surgery 148:778-82; discussion 782-4. 2010
    ..This is a review of our institution's experience with operative management of pediatric liver cancer over an 18-year period...
  53. pmc Liver transplantation for classical maple syrup urine disease: long-term follow-up in 37 patients and comparative United Network for Organ Sharing experience
    George V Mazariegos
    University of Pittsburgh Medical Center, Pittsburgh, PA, USA
    J Pediatr 160:116-21.e1. 2012
    ..To assess clinical and neurocognitive function in children who have undergone liver transplantation for classical maple syrup urine disease (MSUD)...
  54. ncbi request reprint Recurrence of primary sclerosing cholangitis in pediatric liver transplant recipients
    Veena L Venkat
    Division of Pediatric Gastroenterology, Hepatology, and Nutrition, Children s Hospital of Pittsburgh, University of Pittsburgh Medical Center, Pittsburgh, PA
    Liver Transpl 20:679-86. 2014
    ..Defining the natural history of rPSC and searching for the etiology and risk factors of rPSC are important for the long-term outcomes of pediatric patients...
  55. ncbi request reprint Pharmacodynamics of sirolimus in transplanted children receiving tacrolimus
    Rakesh Sindhi
    Pediatric Transplantation, Children s Hospital of Pittsburgh, 3705 Fifth Avenue, Pittsburgh, PA 15217, USA
    Transplant Proc 34:1960. 2002
  56. pmc Posttransplant lymphoproliferative disorders in liver transplantation: a 20-year experience
    Ashok Jain
    Thomas E Starzl Transplantation Institute, the Divisions of Transplantation Surgery and Transplantation Pathology, and the Department of Pediatrics, University of Pittsburgh School of Medicine, Pittsburgh, Pennsylvania 15213, USA
    Ann Surg 236:429-36; discussion 436-7. 2002
    ..To evaluate the incidence of posttransplant lymphoproliferative disease (PTLD) and the risk factors and the impact of this complication on survival outcomes in a large cohort of liver transplant recipients at a single institution...
  57. ncbi request reprint Sirolimus pharmacokinetic differences between children and adults
    Raman Venkataramanan
    Pediatr Transplant 10:872-4. 2006
  58. ncbi request reprint HSV infection and immunosuppression
    Rakesh Sindhi
    Liver Transpl 12:1906-7. 2006
  59. ncbi request reprint Isolated liver transplantation in infants with short gut syndrome: is less better?
    George V Mazariegos
    Liver Transpl 12:1040-1. 2006
  60. ncbi request reprint PELD allocation and acute liver/graft failure
    Rakesh Sindhi
    Liver Transpl 13:776-7. 2007
  61. ncbi request reprint Preventing acute and chronic rejection after diagnosis of post-transplantation lymphoproliferative disorder
    Rakesh Sindhi
    Pediatr Transplant 7:339-41. 2003