Mary Rose

Summary

Affiliation: Children's National Medical Center
Country: USA

Publications

  1. pmc Glucocorticoid receptor and histone deacetylase-2 mediate dexamethasone-induced repression of MUC5AC gene expression
    Yajun Chen
    Center for Genetic Medicine Research, Children s National Medical Center, Washington, DC, USA
    Am J Respir Cell Mol Biol 47:637-44. 2012
  2. ncbi request reprint Model systems for investigating mucin gene expression in airway diseases
    M C Rose
    Children s Research Institute, Children s National Medical Center, Washington, DC 20010, USA
    J Aerosol Med 13:245-61. 2000
  3. ncbi request reprint Respiratory tract mucin genes and mucin glycoproteins in health and disease
    Mary Callaghan Rose
    Research Center for Genetic Medicine, Room 5700, Children s National Medical Center, 111 Michigan Avenue NW, Washington, DC 20010, USA
    Physiol Rev 86:245-78. 2006
  4. pmc Cigarette smoke activates NF kappa B and induces Muc5b expression in mouse middle ear cells
    Diego Preciado
    Center for Genetic Medicine Research, Children s National Medical Center, Washington, DC 20010, USA
    Laryngoscope 118:464-71. 2008
  5. pmc Cigarette smoke activates NFκB-mediated Tnf-α release from mouse middle ear cells
    Diego Preciado
    Center for Genetic Medicine Research, Georgetown University, Washington, DC 20010, USA
    Laryngoscope 120:2508-15. 2010
  6. doi request reprint In vitro effects of acid and pepsin on mouse middle ear epithelial cell viability and MUC5B gene expression
    Bradley B Block
    Division of Pediatric Otolaryngology Head and Neck Surgery, Children s National Medical Center, 111 Michigan Ave NW, Washington, DC 20010, USA
    Arch Otolaryngol Head Neck Surg 136:37-42. 2010
  7. pmc Human bronchial epithelial cells differentiate to 3D glandular acini on basement membrane matrix
    Xiaofang Wu
    Center for Genetic Medicine Research, Children s National Medical Center, Washington, DC 20010, USA
    Am J Respir Cell Mol Biol 44:914-21. 2011

Collaborators

  • Judith Voynow
  • Diego Preciado
  • Yajun Chen
  • Xiaofang Wu
  • Bradley B Block
  • Alan M Watson
  • Anamaris M Colberg-Poley
  • Michael Rahimi
  • Chad D Williamson
  • Chong Liang
  • Maria T Pena
  • Jennifer R Peters-Hall
  • Sumit Bose
  • Habib G Zalzal
  • Elaine Kuo
  • Hugo Escobar

Detail Information

Publications7

  1. pmc Glucocorticoid receptor and histone deacetylase-2 mediate dexamethasone-induced repression of MUC5AC gene expression
    Yajun Chen
    Center for Genetic Medicine Research, Children s National Medical Center, Washington, DC, USA
    Am J Respir Cell Mol Biol 47:637-44. 2012
    ..A better understanding of the mechanisms whereby glucocorticoids repress MUC5AC gene expression may be useful in formulating therapeutic interventions in chronic lung diseases...
  2. ncbi request reprint Model systems for investigating mucin gene expression in airway diseases
    M C Rose
    Children s Research Institute, Children s National Medical Center, Washington, DC 20010, USA
    J Aerosol Med 13:245-61. 2000
    ....
  3. ncbi request reprint Respiratory tract mucin genes and mucin glycoproteins in health and disease
    Mary Callaghan Rose
    Research Center for Genetic Medicine, Room 5700, Children s National Medical Center, 111 Michigan Avenue NW, Washington, DC 20010, USA
    Physiol Rev 86:245-78. 2006
    ..The underlying premise is that understanding the pathways and processes that lead to mucus overproduction in specific airway diseases will allow circumvention or amelioration of these processes...
  4. pmc Cigarette smoke activates NF kappa B and induces Muc5b expression in mouse middle ear cells
    Diego Preciado
    Center for Genetic Medicine Research, Children s National Medical Center, Washington, DC 20010, USA
    Laryngoscope 118:464-71. 2008
    ..We hypothesized that in vitro stimulation of a recently developed model system, murine middle ear epithelial cells (MEEC), with cigarette smoke condensate (CSC) activates NF-kappa B and subsequently induces Muc5b gene expression...
  5. pmc Cigarette smoke activates NFκB-mediated Tnf-α release from mouse middle ear cells
    Diego Preciado
    Center for Genetic Medicine Research, Georgetown University, Washington, DC 20010, USA
    Laryngoscope 120:2508-15. 2010
    ..We hypothesized that stimulation of murine middle ear epithelial cells (MEEC) with cigarette smoke condensate (CSC) activates NF-κB resulting in upregulation of proinflammatory cytokines...
  6. doi request reprint In vitro effects of acid and pepsin on mouse middle ear epithelial cell viability and MUC5B gene expression
    Bradley B Block
    Division of Pediatric Otolaryngology Head and Neck Surgery, Children s National Medical Center, 111 Michigan Ave NW, Washington, DC 20010, USA
    Arch Otolaryngol Head Neck Surg 136:37-42. 2010
    ..To examine whether in vitro exposure of mouse middle ear epithelial cells (mMEECs) to conditions that mimic physiologic reflux upregulates Muc5b gene expression and alters cell viability...
  7. pmc Human bronchial epithelial cells differentiate to 3D glandular acini on basement membrane matrix
    Xiaofang Wu
    Center for Genetic Medicine Research, Children s National Medical Center, Washington, DC 20010, USA
    Am J Respir Cell Mol Biol 44:914-21. 2011
    ..These results demonstrated that this in vitro model system is reproducible, stable, and potentially useful for studies of glandular differentiation and hyperplasia...