Natella Y Rakhmanina

Summary

Affiliation: Children's National Medical Center
Country: USA

Publications

  1. pmc Pharmacotherapy of pediatric HIV infection
    Natella Rakhmanina
    Division of Infectious Diseases, Children s National Medical Center, Washington, DC 20010, USA
    Pediatr Clin North Am 59:1093-115. 2012
  2. ncbi request reprint Pharmacokinetic considerations of perinatal antiretroviral therapy
    Natella Y Rakhmanina
    Division of Infectious Disease, Children s National Medical Center, George Washington University School of Medicine and Health Sciences, Washington, DC, USA
    Curr Drug Metab 13:744-59. 2012
  3. pmc High dose of darunavir in treatment-experienced HIV-infected adolescent results in virologic suppression and improved CD4 cell count
    Natella Y Rakhmanina
    Division of Infectious Diseases, Department of Pediatrics, Children s National Medical Center, George Washington University School of Medicine and Health Sciences, Washington, DC 20010, USA
    Ther Drug Monit 34:237-41. 2012
  4. pmc CYP3A5, ABCB1, and SLCO1B1 polymorphisms and pharmacokinetics and virologic outcome of lopinavir/ritonavir in HIV-infected children
    Natella Y Rakhmanina
    Division of Infectious Diseases, Children s National Medical Center, Washington, DC, USA
    Ther Drug Monit 33:417-24. 2011
  5. doi request reprint Treating an HIV-infected paediatric patient: an easy task?
    Natella Y Rakhmanina
    Division of Infectious Disease, Children s National Medical Center, Washington, DC, USA
    Antivir Ther 15:293-6. 2010
  6. pmc Can therapeutic drug monitoring improve pharmacotherapy of HIV infection in adolescents?
    Natella Y Rakhmanina
    Division of Infectious Disease, Children s National Medical Center, Washington, DC, USA
    Ther Drug Monit 32:273-81. 2010
  7. pmc Efavirenz in the therapy of HIV infection
    Natella Y Rakhmanina
    The George Washington University, School of Medicine and Health Sciences, Department of Pediatrics, and Special Immunology Program, Children s National Medical Center, Division of Infectious Disease, Washington, DC 20010, USA
    Expert Opin Drug Metab Toxicol 6:95-103. 2010
  8. doi request reprint Epidemiology of new cases of HIV-1 infection in children referred to the metropolitan pediatric hospital in Washington, DC
    Natella Y Rakhmanina
    Division of Infectious Disease, The George Washington University School of Medicine and Health Sciences, Washington, DC 20010, USA
    Pediatr Infect Dis J 27:837-9. 2008
  9. ncbi request reprint Nevirapine concentration in nonstimulated saliva: an alternative to plasma sampling in children with human immunodeficiency virus infection
    Natella Y Rakhmanina
    Division of Infectious Disease, The George Washington University School of Medicine, Washington, DC 20010, USA
    Ther Drug Monit 29:110-7. 2007
  10. ncbi request reprint Therapeutic drug monitoring for patients with HIV infection: Children's National Medical Center, Washington DC experience
    Steven J Soldin
    Department of Pediatrics, The George Washington University School of Medicine, Washington, DC, USA
    Ther Drug Monit 26:107-9. 2004

Detail Information

Publications14

  1. pmc Pharmacotherapy of pediatric HIV infection
    Natella Rakhmanina
    Division of Infectious Diseases, Children s National Medical Center, Washington, DC 20010, USA
    Pediatr Clin North Am 59:1093-115. 2012
    ..The authors review the evolution in treatment of pediatric HIV from infancy through adolescence...
  2. ncbi request reprint Pharmacokinetic considerations of perinatal antiretroviral therapy
    Natella Y Rakhmanina
    Division of Infectious Disease, Children s National Medical Center, George Washington University School of Medicine and Health Sciences, Washington, DC, USA
    Curr Drug Metab 13:744-59. 2012
    ..In this paper we provide an overview of published studies of ART disposition during pregnancy, labor, breastfeeding and in the newborn infant after delivery...
  3. pmc High dose of darunavir in treatment-experienced HIV-infected adolescent results in virologic suppression and improved CD4 cell count
    Natella Y Rakhmanina
    Division of Infectious Diseases, Department of Pediatrics, Children s National Medical Center, George Washington University School of Medicine and Health Sciences, Washington, DC 20010, USA
    Ther Drug Monit 34:237-41. 2012
    ..Pharmacokinetic and pharmacodynamic evaluations justified the individualized use of high-dose darunavir, which resulted in virologic suppression, improved CD4 cell count, and resolution of toxicity...
  4. pmc CYP3A5, ABCB1, and SLCO1B1 polymorphisms and pharmacokinetics and virologic outcome of lopinavir/ritonavir in HIV-infected children
    Natella Y Rakhmanina
    Division of Infectious Diseases, Children s National Medical Center, Washington, DC, USA
    Ther Drug Monit 33:417-24. 2011
    ..The aim of this study was to investigate the influence of CYP3A5 A6986G, ABCB1 (C3435T and G2677T), and SLCO1B1 (T521C and A388AG) polymorphisms on the PK and virologic outcome of lopinavir/ritonavir (LPV/RTV) in HIV-infected children...
  5. doi request reprint Treating an HIV-infected paediatric patient: an easy task?
    Natella Y Rakhmanina
    Division of Infectious Disease, Children s National Medical Center, Washington, DC, USA
    Antivir Ther 15:293-6. 2010
    ..Pharmacokinetics and pharmacodynamic studies of antiretroviral drugs and their combinations need to be conducted in infants, children and adolescents to develop appropriate dosing in each of these specific groups...
  6. pmc Can therapeutic drug monitoring improve pharmacotherapy of HIV infection in adolescents?
    Natella Y Rakhmanina
    Division of Infectious Disease, Children s National Medical Center, Washington, DC, USA
    Ther Drug Monit 32:273-81. 2010
    ..Finally, TDM in adolescents provides valuable information about the clinical pharmacology of ART during puberty...
  7. pmc Efavirenz in the therapy of HIV infection
    Natella Y Rakhmanina
    The George Washington University, School of Medicine and Health Sciences, Department of Pediatrics, and Special Immunology Program, Children s National Medical Center, Division of Infectious Disease, Washington, DC 20010, USA
    Expert Opin Drug Metab Toxicol 6:95-103. 2010
    ..EFV is the only antiretroviral agent currently on the market that has been combined with emtricitabine and tenofovir disoproxil fumarate in a single tablet and administered once daily...
  8. doi request reprint Epidemiology of new cases of HIV-1 infection in children referred to the metropolitan pediatric hospital in Washington, DC
    Natella Y Rakhmanina
    Division of Infectious Disease, The George Washington University School of Medicine and Health Sciences, Washington, DC 20010, USA
    Pediatr Infect Dis J 27:837-9. 2008
    ..Nonimmigrant mothers (30.4%) used illicit drugs (P < 0.001), and 50% of immigrant mothers breast-fed their children (P < 0.001). These data can guide intervention strategies...
  9. ncbi request reprint Nevirapine concentration in nonstimulated saliva: an alternative to plasma sampling in children with human immunodeficiency virus infection
    Natella Y Rakhmanina
    Division of Infectious Disease, The George Washington University School of Medicine, Washington, DC 20010, USA
    Ther Drug Monit 29:110-7. 2007
    ....
  10. ncbi request reprint Therapeutic drug monitoring for patients with HIV infection: Children's National Medical Center, Washington DC experience
    Steven J Soldin
    Department of Pediatrics, The George Washington University School of Medicine, Washington, DC, USA
    Ther Drug Monit 26:107-9. 2004
    ..Also discussed are the preliminary new and original data on free antiretroviral drug measurement in both plasma and saliva...
  11. ncbi request reprint Therapeutic drug monitoring of antiretroviral therapy
    Natella Y Rakhmanina
    Special Immunology Program, Children s National Medical Center, Washington, DC 20010 2970, USA
    AIDS Patient Care STDS 18:7-14. 2004
    ..This review includes an illustrative case report of measuring concentrations of antiretroviral drugs in a pediatric patient...
  12. ncbi request reprint Safety and pharmacokinetics of antiretroviral therapy during pregnancy
    Natella Y Rakhmanina
    Special Immunology Program, Children s National Medical Center, Washington, DC 20010 2970, USA
    Ther Drug Monit 26:110-5. 2004
    ..The available pharmacokinetic data regarding the use of antiretroviral therapy in pregnancy is reviewed...
  13. pmc A urinary biomarker profile for children with HIV-associated renal diseases
    Angel A Soler-García
    Center for Molecular Physiology Research, Division of Nephrology, Children s National Medical Center, Children s Research Institute, Washington, District of Columbia 20010, USA
    Kidney Int 76:207-14. 2009
    ..Our findings suggest that this urinary growth factor profile may be useful in facilitating the diagnosis of HIV-infected children at risk of developing HIVAN when interpreted in the appropriate clinical setting...
  14. ncbi request reprint Pharmacological research in pediatrics: From neonates to adolescents
    Natella Y Rakhmanina
    Division of Pediatric Clinical Pharmacology, Children s National Medical Center, 111 Michigan Avenue, N W, Washington, DC 20010, USA
    Adv Drug Deliv Rev 58:4-14. 2006
    ..This review will give some of the history and current progress in pharmacological research and pediatric drug development...