Research Topics
| D R NordliSummaryAffiliation: Children's Memorial Hospital Country: USA Publications
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Detail Information
Publications
When do seizures usually improve with the ketogenic diet?Eric H Kossoff
Department of Neurology, The Johns Hopkins Medical Institutions, Baltimore, Maryland 21287, USA
Epilepsia 49:329-33. 2008..The purpose of this study was to determine the typical time to seizure reduction as well as the time after which it was unlikely to be helpful in those children started on the KD...
Epilepsy syndromes in infancyChristian M Korff
Epilepsy Center, Children's Memorial Hospital, Chicago, Illinois 60614-3394, USA
Pediatr Neurol 34:253-63. 2006..Issues related to their classification are addressed...
Combined ketogenic diet and vagus nerve stimulation: rational polytherapy?Eric H Kossoff
The Johns Hopkins Hospital, Baltimore, Maryland 21287 1000, USA
Epilepsia 48:77-81. 2007..The concept of "rational polypharmacy" has been associated with anticonvulsant management for decades, but the term has not been applied to nonpharmacologic therapies...
Varying seizure semiology according to ageDouglas R Nordli
Epilepsy Center, Children s Memorial Hospital, Chicago, IL, USA Electronic address
Handb Clin Neurol 111:455-60. 2013..A detailed knowledge of seizure semiology can make the history more effective and also in the identification of the correct seizure classification...
Epileptic encephalopathies in infants and childrenDouglas R Nordli
Department of Pediatrics, Children s Memorial Hospital, Feinberg School of Medicine, Northwestern University, Chicago, IL, USA
J Clin Neurophysiol 29:420-4. 2012..Recognition and accurate classification of these severe epilepsies is important as the first step toward improving treatment and outcomes...
Cellular injury and neuroinflammation in children with chronic intractable epilepsyJieun Choi
Department of Pediatrics, Northwestern University Children s Memorial Hospital, Chicago, IL, USA
J Neuroinflammation 6:38. 2009....
Usefulness of video-EEG monitoringDouglas R Nordli
Childrens Memorial Hospital, Northwest University, Chicago, Illinois 60657, USA
Epilepsia 47:26-30. 2006..The information gleaned from an analysis of the ictal events can be very helpful in clarifying the true nature of the epilepsies. Several illustrative clinical cases will be briefly discussed to highlight these points...
Idiopathic generalized epilepsies recognized by the International League Against EpilepsyDouglas R Nordli
Children s Memorial Hospital, Northwestern University, Feinberg School of Medicine, Chicago, Illinois 60614, USA
Epilepsia 46:48-56. 2005..At the current time, clinical features are still the cornerstone of accurate classification, and accurate classification, in turn, is the best predictor of outcome...
Classification of infantile seizures: implications for identification and treatment of inborn errors of metabolismDouglas R Nordli
Department of Pediatrics, Lorna S and James P Langdon Chair of Pediatric Epilepsy, Children s Memorial Hospital, Northwestern University, Chicago, Illinois 60614 3394, USA
J Child Neurol 17:3S3-7; discussion 3S8. 2002..Earlier recognition of metabolic disorders may be accomplished by careful study of clinical and electrographic characteristics. There are important treatment considerations associated with these disorders...
The ketogenic diet: uses and abusesDouglas Nordli
Northwestern University Medical School, Children's Memorial Hospittal, Chicago, IL 60614, USA
Neurology 58:S21-4. 2002
Advances in our understanding of early childhood epilepsies: 1999-2000D R Nordli
Children s Epilepsy Center, Children s Memorial Hospital, 2300 Children s Plaza, Chicago, IL 60614 3394, USA
Curr Neurol Neurosci Rep 1:390-5. 2001..For a variety of reasons and incentives, it is likely that research focusing on infants and young children will continue at a brisk pace...
Experience with the ketogenic diet in infantsD R Nordli
Epilepsy Center, Children s Memorial Hospital, Chicago, Illinois, USA
Pediatrics 108:129-33. 2001..To evaluate the effectiveness, tolerability, and adverse effects of the ketogenic diet in infants with refractory epilepsy...
Special needs of the adolescent with epilepsyD R Nordli
Children s Epilepsy Center, Children s Memorial Hospital, Chicago, Illinois 60614 3394, USA
Epilepsia 42:10-7. 2001..Some centers have developed elegant methods of helping the patient make the transition from child neurology to adult neurology...
The ontogeny of partial seizures in infants and young childrenD R Nordli
Epilepsy Center, Children s Memorial Hospital, Chicago, Illinois, USA
Epilepsia 42:986-90. 2001..To describe the clinical manifestations of partial seizures in the pediatric population as a function of age...
Child Neurology: Dravet syndrome: when to suspect the diagnosisJohn J Millichap
Division of Neurology, Children s Memorial Hospital, Northwestern University Medical School, Chicago, IL 60614, USA
Neurology 73:e59-62. 2009..Early recognition and diagnosis of DS and management with appropriate anticonvulsants and treatment plan may reduce the seizure burden and improve long-term developmental outcome...
Infantile seizures and epilepsy syndromesDouglas R Nordli
Children's Memorial Hospital, Chicago, Illinois 60614, USA
Epilepsia 43:11-6. 2002..Whether the various presentations of epilepsy in infants can be cleanly separated into these categories, or need to be considered as points along a biologic spectrum, will require further research...
Paroxysmal events in infants: persistent eye closure makes seizures unlikelyChristian M Korff
Epilepsy Center, Children s Memorial Hospital, Chicago, IL 60614 3394, USA
Pediatrics 116:e485-6. 2005..The aim of this study was to determine the frequency of eye opening during infantile seizures and evaluate the potential usefulness of this simple observation in the differential diagnosis of acute events in infants...
Ictal asystole and anti-N-methyl-D-aspartate receptor antibody encephalitisJohn J Millichap
Epilepsy Center, Division of Neurology, Children s Memorial Hospital, 2300 Children s Plaza, Box 29, Chicago, IL 60614, USA
Pediatrics 127:e781-6. 2011....
Diagnostic difficulty in infants and childrenDouglas R Nordli
Children s Epilepsy Center, Children s Memorial Hospital, Chicago, IL 60614 3394, USA
J Child Neurol 17:S28-35. 2002....
Epilepsy syndromes undetermined whether focal or generalized in infantsChristian M Korff
Epilepsy Center, Box #29, Children's Memorial Hospital, 2300 Children's Plaza, Chicago, IL 60614-3394, USA
Epilepsy Res 70:S105-9. 2006..We believe these epilepsies are not uncommon in the group of infants with intractable seizures and may have yet to be discovered metabolic and genetic determinants...
The clinical-electrographic expression of infantile seizuresChristian M Korff
Epilepsy Center, Box # 29, Children's Memorial Hospital, 2300 Children's Plaza, Chicago, IL 60614-3394, USA
Epilepsy Res 70:S116-31. 2006..Video-EEG findings and accurate seizure classification may add fundamental information with regards to epilepsy syndrome diagnosis and specific treatment options, including surgery...
The management of epilepsy in children: cognitive and behavioral side effectsDouglas R Nordli
Northwestern University, Feinberg School of Medicine, Children's Memorial Hospital, Chicago, IL, USA
Rev Neurol Dis 1:S4-9. 2004....
Do generalized tonic-clonic seizures in infancy exist?Christian Korff
Epilepsy Center, Children s Memorial Hospital, Chicago, IL 60614 3394, USA
Neurology 65:1750-3. 2005..To determine the frequency of generalized tonic-clonic seizures (GTCS) in infants (1 month to 2 years)...
The role of EEG in febrile status epilepticus (FSE)D R Nordli
Children s Memorial Hospital, 2300 Children s Plaza, No 29, Chicago, IL 60614, USA
Brain Dev 32:37-41. 2010..Prospective series with large numbers of patients and follow-up are required to ascertain whether such abnormalities are associated with later development of epilepsy...
Selection and evaluation of children for epilepsy surgeryD R Nordli
Children s Memorial Hospital, Chicago, IL 60614, USA
Pediatr Neurosurg 34:1-12. 2001..Surgery for intractable epilepsy can be a rewarding therapy, and in select children, the only chance for cure and substantial development progress...
Notched delta, phenotype, and Angelman syndromeChristian M Korff
Epilepsy Center, Children's Memorial Hospital, Chicago, Illinois 60614-3394, USA
J Clin Neurophysiol 22:238-43. 2005..It is a powerful detection tool for Angelman syndrome when correlated to a suggestive phenotype, and the association of these features should raise suspicion for Angelman syndrome in both infants and adults...
Autonomic status epilepticus in Panayiotopoulos syndrome and other childhood and adult epilepsies: a consensus viewColin D Ferrie
Department of Paediatric Neurology, Leeds General Infirmary, United Kingdom
Epilepsia 48:1165-72. 2007..To discuss and propose a definition of autonomic status epilepticus (SE), describe its clinical and EEG features, and review what is known about its epidemiology, pathophysiology, differential diagnosis, and management...
Cryptogenic late-onset epileptic spasms or late infantile epileptogenic encephalopathy?Douglas R Nordli
Epilepsia 48:206-8. 2007
Abruptly attenuated terminal ictal pattern in pediatricsAndrew J Kim
Childrens Hospital Los Angeles, Keck School of Medicine of the University of Southern California, Division of Neurology, Los Angeles, California, USA
J Clin Neurophysiol 23:532-50. 2006..We examined the ictal discharges at the end of pediatric seizures and categorized the various patterns. One particular pattern, termed "abruptly attenuated termination" was studied in detail...
Seizure characterization and electroencephalographic features in Glut-1 deficiency syndromeLinda D Leary
Department of Neurology, Columbia University College of Physicians and Surgeons, New York, New York, U S A
Epilepsia 44:701-7. 2003..To characterize seizure types and electroencephalographic features of glucose transporter type 1 deficiency syndrome (Glut-1 DS)...
Diagnosis and management of nonconvulsive status epilepticus in childrenChristian M Korff
Children s Hospital, Geneva, Switzerland
Nat Clin Pract Neurol 3:505-16. 2007..By contrast, a cautious approach seems to be indicated for absence status epilepticus, complex partial status epilepticus and electrical status epilepticus during sleep...
