Joseph E Losee

Summary

Affiliation: Children's Hospital of Pittsburgh
Country: USA

Publications

  1. ncbi Deformational plagiocephaly: diagnosis, prevention, and treatment
    Joseph E Losee
    Department of Surgery, University of Pittsburgh Medical School, 3550 Terrace Street, Pittsburgh, PA 15261, USA
    Clin Plast Surg 32:53-64, viii. 2005
  2. ncbi Macromastia as an etiologic factor in bulimia nervosa: 10-year follow up after treatment with reduction mammaplasty
    Joseph E Losee
    Children s Hospital of Pittsburgh, Division of Pediatric Plastic Surgery, University of Pittsburgh, Pittsburgh, Pennsylvania 15213, USA
    Ann Plast Surg 52:452-7; discussion 457. 2004
  3. ncbi Nonsynostotic occipital plagiocephaly: radiographic diagnosis of the "sticky suture"
    Joseph E Losee
    The Childrens Hospital of Pittsburgh, Division of Pediatric Plastic Surgery, University of Pittsburgh, Pittsburgh, PA, USA
    Plast Reconstr Surg 116:1860-9. 2005
  4. ncbi Congenital nasal anomalies: a classification scheme
    Joseph E Losee
    Division of Plastic Surgery, Children s Hospital of Philadelphia, PA, USA
    Plast Reconstr Surg 113:676-89. 2004
  5. ncbi Acellular dermal matrix in palatoplasty
    Joseph E Losee
    Division of Plastic Surgery, University of Pittsburgh Medical Center, Pittsburgh, Pennsylvania, USA
    Aesthet Surg J 31:108S-15S. 2011
  6. ncbi Pediatric orbital fractures: classification, management, and early follow-up
    Joseph E Losee
    Division of Pediatric Plastic Surgery, Children s Hospital of Pittsburgh, 3507 Fifth Avenue, Pittsburgh, PA 15213 2583, USA
    Plast Reconstr Surg 122:886-97. 2008
  7. ncbi A successful algorithm for limiting postoperative fistulae following palatal procedures in the patient with orofacial clefting
    Joseph E Losee
    Division of Plastic Surgery, Children s Hospital of Pittsburgh, University of Pittsburgh, Pittsburgh, PA 15213, USA
    Plast Reconstr Surg 122:544-54. 2008
  8. ncbi Nonsynostotic occipital plagiocephaly: factors impacting onset, treatment, and outcomes
    Joseph E Losee
    Division of Pediatric Plastic Surgery, Department of Surgery, Children s Hospital of Pittsburgh, Pittsburgh, PA 15213, USA
    Plast Reconstr Surg 119:1866-73. 2007
  9. ncbi Novel model of calvarial defect in an infected unfavorable wound: reconstruction with rhBMP-2. Part II
    Christopher R Kinsella
    Division of Plastic Surgery, University of Pittsburgh, Pittsburgh, PA 15201, USA
    J Craniofac Surg 23:410-4. 2012
  10. pmc Direct comparison of progenitor cells derived from adipose, muscle, and bone marrow from wild-type or craniosynostotic rabbits
    Gregory M Cooper
    Department of Surgery, University of Pittsburgh, Pittsburgh, PA, USA
    Plast Reconstr Surg 127:88-97. 2011

Collaborators

Detail Information

Publications76

  1. ncbi Deformational plagiocephaly: diagnosis, prevention, and treatment
    Joseph E Losee
    Department of Surgery, University of Pittsburgh Medical School, 3550 Terrace Street, Pittsburgh, PA 15261, USA
    Clin Plast Surg 32:53-64, viii. 2005
    ....
  2. ncbi Macromastia as an etiologic factor in bulimia nervosa: 10-year follow up after treatment with reduction mammaplasty
    Joseph E Losee
    Children s Hospital of Pittsburgh, Division of Pediatric Plastic Surgery, University of Pittsburgh, Pittsburgh, Pennsylvania 15213, USA
    Ann Plast Surg 52:452-7; discussion 457. 2004
    ..This could, in part, represent a surgical treatment of a psychologic abnormality. Consequently, the presence of an eating disorder should not automatically exclude a woman from surgical consideration...
  3. ncbi Nonsynostotic occipital plagiocephaly: radiographic diagnosis of the "sticky suture"
    Joseph E Losee
    The Childrens Hospital of Pittsburgh, Division of Pediatric Plastic Surgery, University of Pittsburgh, Pittsburgh, PA, USA
    Plast Reconstr Surg 116:1860-9. 2005
    ..The aim of this study was to characterize morphological differences in the lambdoid suture between nonsynostotic occipital plagiocephaly and lambdoid craniosynostosis...
  4. ncbi Congenital nasal anomalies: a classification scheme
    Joseph E Losee
    Division of Plastic Surgery, Children s Hospital of Philadelphia, PA, USA
    Plast Reconstr Surg 113:676-89. 2004
    ..Type IV deformities consist of neoplasms and vascular anomalies. Both benign and malignant neoplasms are found in this category...
  5. ncbi Acellular dermal matrix in palatoplasty
    Joseph E Losee
    Division of Plastic Surgery, University of Pittsburgh Medical Center, Pittsburgh, Pennsylvania, USA
    Aesthet Surg J 31:108S-15S. 2011
    ....
  6. ncbi Pediatric orbital fractures: classification, management, and early follow-up
    Joseph E Losee
    Division of Pediatric Plastic Surgery, Children s Hospital of Pittsburgh, 3507 Fifth Avenue, Pittsburgh, PA 15213 2583, USA
    Plast Reconstr Surg 122:886-97. 2008
    ..The aim of this study is to review the authors' experience with the presentation, management, and early follow-up of pediatric orbital fractures...
  7. ncbi A successful algorithm for limiting postoperative fistulae following palatal procedures in the patient with orofacial clefting
    Joseph E Losee
    Division of Plastic Surgery, Children s Hospital of Pittsburgh, University of Pittsburgh, Pittsburgh, PA 15213, USA
    Plast Reconstr Surg 122:544-54. 2008
    ..Presented here is a successful algorithm for performing palatal procedures and decreasing the rate of postoperative fistulas in a large, single-surgeon, consecutive series...
  8. ncbi Nonsynostotic occipital plagiocephaly: factors impacting onset, treatment, and outcomes
    Joseph E Losee
    Division of Pediatric Plastic Surgery, Department of Surgery, Children s Hospital of Pittsburgh, Pittsburgh, PA 15213, USA
    Plast Reconstr Surg 119:1866-73. 2007
    ..Nonsynostotic occipital plagiocephaly remains a diagnosis of concern in infancy. This study evaluates factors affecting the onset, treatment, and outcomes of nonsynostotic occipital plagiocephaly...
  9. ncbi Novel model of calvarial defect in an infected unfavorable wound: reconstruction with rhBMP-2. Part II
    Christopher R Kinsella
    Division of Plastic Surgery, University of Pittsburgh, Pittsburgh, PA 15201, USA
    J Craniofac Surg 23:410-4. 2012
    ..The purpose of this study was to compare the effectiveness of rhBMP-2 in a rabbit model of an unfavorable scarred calvarial wound with the criterion standard of autograft...
  10. pmc Direct comparison of progenitor cells derived from adipose, muscle, and bone marrow from wild-type or craniosynostotic rabbits
    Gregory M Cooper
    Department of Surgery, University of Pittsburgh, Pittsburgh, PA, USA
    Plast Reconstr Surg 127:88-97. 2011
    ..In this article, the authors compare cells isolated from wild-type rabbits or rabbits with nonsyndromic craniosynostosis, defined as the premature fusion of one or more of the cranial sutures...
  11. ncbi Recombinant human bone morphogenetic protein-2-induced craniosynostosis and growth restriction in the immature skeleton
    Christopher R Kinsella
    Division of Plastic Surgery, University of Pittsburgh, Pittsburgh, PA, USA
    Plast Reconstr Surg 127:1173-81. 2011
    ..In the skeletally immature patient, the safety of rhBMP-2 therapy remains uncertain. Experiments are needed that investigate the effect of rhBMP-2 on growth and development in clinically relevant models...
  12. ncbi 215 mandible fractures in 120 children: demographics, treatment, outcomes, and early growth data
    Darren M Smith
    Children s Hospital of Pittsburgh, University of Pittsburgh Medical Center, Pittsburgh, PA 15201, USA
    Plast Reconstr Surg 131:1348-58. 2013
    ..The authors catalogue their experience with pediatric mandible fractures at a major pediatric teaching hospital with reference to demographics, injury type, treatment, and outcomes to inform future management of these injuries...
  13. ncbi Custom porous polyethylene implants for large-scale pediatric skull reconstruction: early outcomes
    Alexander Y Lin
    Division of Plastic Surgery and Department of Oral Biology, University of Pittsburgh, Children s Hospital of Pittsburgh of UPMC, Pittsburgh, Pennsylvania 15201, USA
    J Craniofac Surg 23:67-70. 2012
    ..We present a clinical series that demonstrates successful use of porous polyethylene cranioplasties in large pediatric cranial defects...
  14. ncbi BMP-2-based repair of large-scale calvarial defects in an experimental model: regenerative surgery in cranioplasty
    Darren M Smith
    Division of Plastic Surgery, University of Pittsburgh, Pittsburgh, Pennsylvania, USA
    J Craniofac Surg 19:1315-22. 2008
    ..rhBMP-2/ACS may offer a viable treatment option for craniofacial surgeons facing a shortage of bone, with the potential to replace autologous bone grafts and render their attendant morbidities obsolete...
  15. ncbi Regenerative surgery in cranioplasty revisited: the role of adipose-derived stem cells and BMP-2
    Darren M Smith
    Division of Plastic Surgery, University of Pittsburgh, and Children s Hospital of Pittsburgh, Pittsburgh, PA 15224, USA
    Plast Reconstr Surg 128:1053-60. 2011
    ..In this article, the authors evaluate and compare the relative efficacy of adipose-derived stem cells, bone morphogenetic protein (BMP)-2, and adipose-derived stem cells osteoinduced with BMP-2 in addressing these defects...
  16. ncbi Blocking bone morphogenetic protein function using in vivo noggin therapy does not rescue premature suture fusion in rabbits with delayed-onset craniosynostosis
    James Cray
    Department of Surgery, Division of Plastic and Reconstructive Surgery, University of Pittsburgh, Pittsburgh, PA 15201, USA
    Plast Reconstr Surg 127:1163-72. 2011
    ..The present study was designed to test the hypothesis that BMP inhibition using noggin therapy may rescue sutures destined to fuse by inhibiting initial ossification...
  17. ncbi Novel animal model of calvarial defect: part IV. Reconstruction of a calvarial wound complicated by durectomy
    Zoe M Macisaac
    Department of Plastic Surgery, University of Pittsburgh, Pittsburgh, PA, USA
    Plast Reconstr Surg 131:512e-9e. 2013
    ..The authors assessed the effectiveness of rhBMP-2-mediated bone regeneration in calvarial defects complicated by durectomy...
  18. pmc Tissue interactions between craniosynostotic dura mater and bone
    Gregory M Cooper
    Division of Plastic and Reconstructive Surgery, Department of Surgery, University of Pittsburgh, Pittsburgh, PA 15224, USA
    J Craniofac Surg 23:919-24. 2012
    ....
  19. ncbi Novel animal model of calvarial defect in an infected unfavorable wound: reconstruction with rhBMP-2
    Gary E DeCesare
    Division of Plastic Surgery and the Department of Oral Biology, University of Pittsburgh, Pittsburgh, PA, USA
    Plast Reconstr Surg 127:588-94. 2011
    ..This study was designed to evaluate the efficacy of rhBMP-2/absorbable collagen sponge to improve healing in the previously infected, unfavorable calvarial defect model...
  20. ncbi Nasal tip complications of primary cleft lip nasoplasty
    Matthew Alef
    Children s Hospital of Pittsburgh, Pittsburgh Cleft Craniofacial Center, University of Pittsburgh, 45th St and Penn Ave, Pittsburgh, PA, USA
    J Craniofac Surg 20:1327-33. 2009
    ..A case series of patients with postoperative nasal complications after primary cleft lip nasal surgery is presented...
  21. ncbi Outcomes in pediatric facial fractures: early follow-up in 177 children and classification scheme
    S Alex Rottgers
    Department of Surgery, Division of Plastic and Reconstructive Surgery, University of Pittsburgh, Pittsburgh, Philadelphia, USA
    J Craniofac Surg 22:1260-5. 2011
    ..With longer follow-up and growth and development studies, we will likely see an increase in the incidence of type 3 adverse outcomes. We recommend, whenever possible, conservative treatment of pediatric facial fractures...
  22. ncbi Novel animal model of calvarial defect: part III. Reconstruction of an irradiated wound with rhBMP-2
    Christopher R Kinsella
    Division of Plastic Surgery, University of Pittsburgh, Pittsburgh, PA, USA
    Plast Reconstr Surg 130:643e-650e. 2012
    ..The authors compared the effectiveness of rhBMP-2 with the accepted standard of autologous graft for repair of irradiated calvarial defects...
  23. ncbi Testing causal mechanisms of nonsyndromic craniosynostosis using path analysis of cranial contents in rabbits with uncorrected craniosynostosis
    Wendy Fellows-Mayle
    Department of Neurological Surgery, University of Pittsburgh, Pittsburgh, Pennsylvania, USA
    Cleft Palate Craniofac J 43:524-31. 2006
    ..This study was designed to investigate which model best describes neurocranial changes associated with craniosynostosis in a rabbit model through multivariate path analysis...
  24. ncbi Nonfatal sport-related craniofacial fractures: characteristics, mechanisms, and demographic data in the pediatric population
    Zoe M Macisaac
    Division of Pediatric Plastic Surgery and the Department of Pediatrics, Children s Hospital of Pittsburgh of the University of Pittsburgh Medical Center, University of Pittsburgh School of Medicine, Pittsburgh, PA 15224, USA
    Plast Reconstr Surg 131:1339-47. 2013
    ....
  25. ncbi Leporine-derived adipose precursor cells exhibit in vitro osteogenic potential
    Jason R Dudas
    Division of Plastic Surgery, University of Pittsburgh, Pittsburgh, Pennsylvania, USA
    J Craniofac Surg 19:360-8. 2008
    ..The mechanism underlying the sex-based variation in osteoblastic differentiation is unknown but may involve signaling via factors such as estrogen...
  26. ncbi Reconstruction of the immature craniofacial skeleton with a carbonated calcium phosphate bone cement: interaction with bioresorbable mesh
    Joseph E Losee
    Division of Plastic Surgery, The Children s Hospital at Strong and the University of Rochester, Rochester, New York 14642, USA
    J Craniofac Surg 14:117-24. 2003
    ..Calcium phosphate cement may be safely used for craniofacial reconstruction in the presence of PLA implants without compromise to its biocompatibility, osteoconductivity, or remodeling capacity...
  27. ncbi BMP-2-mediated regeneration of large-scale cranial defects in the canine: an examination of different carriers
    Christopher R Kinsella
    Division of Plastic Surgery and Department of Oral Biology, University of Pittsburgh, Pittsburgh, PA, USA
    Plast Reconstr Surg 127:1865-73. 2011
    ..The aim of the authors' study was to investigate the use of rhBMP-2 in addressing calvarial defects in a large-animal model through a variety of modifications to this U.S. Food and Drug Administration-approved therapy...
  28. pmc Masticatory hypermuscularity is not related to reduced cranial volume in myostatin-knockout mice
    James Cray
    Division of Plastic and Reconstructive Surgery, Department of Surgery, University of Pittsburgh, Pennsylvania 15201, USA
    Anat Rec (Hoboken) 294:1170-7. 2011
    ..The results presented here do not support the hypothesis that a reduction in masticatory musculature relaxed compressive forces on the cranial vault allowing for greater encephalization...
  29. ncbi Bone morphogenetic protein 2 therapy for craniofacial surgery
    Darren M Smith
    University of Pittsburgh, Division of Plastic Surgery, Pittsburgh, Pennsylvania, USA
    J Craniofac Surg 19:1244-59. 2008
    ....
  30. ncbi Pediatric facial fractures: demographics, injury patterns, and associated injuries in 772 consecutive patients
    Lorelei Grunwaldt
    Department of Pediatrics, University of Pittsburgh Medical Center, Pittsburgh, PA, USA
    Plast Reconstr Surg 128:1263-71. 2011
    ..Here, the authors aim to provide context for practitioners managing pediatric facial fractures by augmenting presently available demographic, diagnostic, and treatment data...
  31. ncbi Scalp reconstruction: regeneration with acellular dermal matrix
    Christopher R Kinsella
    Division of Pediatric Plastic Surgery, Children s Hospital of Pittsburgh of UPMC, University of Pittsburgh, Pittsburgh, Pennsylvania 15224, USA
    J Craniofac Surg 21:605-7. 2010
    ..Our group proposes a novel use of acellular dermal matrix (ADM) to preserve these deficient areas without the need for excision or staged management of osteomyelitic calvaria...
  32. ncbi Effects of flutamide therapy on craniofacial growth and development in a model of craniosynostosis
    James Cray
    Department of Surgery, Division of Plastic and Reconstructive Surgery, University of Pittsburgh, Children s Hospital of Pittsburgh, Pittsburgh, Pennsylvania 15201, USA
    J Craniofac Surg 21:711-8. 2010
    ..Results suggest that androgen receptor-blocking using flutamide may only provide a transient rescue to suture fusion in this model. Further research is needed to investigate the effects of hormones on suture development and maintenance...
  33. ncbi Ex vivo Noggin gene therapy inhibits bone formation in a mouse model of postoperative resynostosis
    Gregory M Cooper
    Department of Surgery, University of Pittsburgh, Pittsburgh, PA, USA
    Plast Reconstr Surg 123:94S-103S. 2009
    ..This study tested the hypothesis that treatment of suturectomy sites with Noggin, an extracellular antagonist of bone morphogenetic proteins, would inhibit postoperative resynostosis in a mouse suturectomy model...
  34. ncbi Noggin inhibits postoperative resynostosis in craniosynostotic rabbits
    Gregory M Cooper
    Department of Surgery, Division of Pediatric Plastic Surgery, University of Pittsburgh, Pittsburgh, Pennsylvania 15213, USA
    J Bone Miner Res 22:1046-54. 2007
    ..This study used a single dose of Noggin protein to prevent resynostosis and improve postoperative outcomes in a rabbit model of craniosynostosis...
  35. ncbi Precise control of osteogenesis for craniofacial defect repair: the role of direct osteoprogenitor contact in BMP-2-based bioprinting
    Darren M Smith
    University of Pittsburgh Medical Center, Pittsburgh, PA, USA
    Ann Plast Surg 69:485-8. 2012
    ..Here, we investigate the importance of direct contact between bioprinted BMP-2 and the dura mater (a source of osteoprogenitors) in mediating calvarial healing...
  36. pmc Testing the critical size in calvarial bone defects: revisiting the concept of a critical-size defect
    Gregory M Cooper
    Department of Surgery, Division of Plastic Surgery, University of Pittsburgh, PA, USA
    Plast Reconstr Surg 125:1685-92. 2010
    ..This study was undertaken to test the concept of the critical size in several different models. A review of the theoretical and scientific bases for the critical-size defect was also undertaken...
  37. ncbi Demineralized bone matrix and resorbable mesh bilaminate cranioplasty: a novel method for reconstruction of large-scale defects in the pediatric calvaria
    Mimi T Chao
    Division of Pediatric Plastic Surgery, Children s Hospital of Pittsburgh, University of Pittsburgh, PA, USA
    Plast Reconstr Surg 123:976-82. 2009
    ..The authors present their experience using demineralized bone matrix and resorbable mesh bilaminate for the repair of large-scale cranial defects in pediatric patients...
  38. ncbi The Pittsburgh Fistula Classification System: a standardized scheme for the description of palatal fistulas
    Darren M Smith
    Children s Hospital of Pittsburgh, Division of Pediatric Plastic Surgery, and Center for Craniofacial and Dental Genetics, Department of Oral Biology, School of Dental Medicine, University of Pittsburgh, PA 15213, USA
    Cleft Palate Craniofac J 44:590-4. 2007
    ..We endeavor to devise a palatal fistula classification system that may have clinical and research applicability...
  39. ncbi Parasagittal suture after strip craniectomy
    Christopher R Kinsella
    Divisions of Pediatric Plastic Surgery, Children s Hospital of Pittsburgh of UPMC, University of Pittsburgh, Pittsburgh, Pennsylvania, USA
    J Craniofac Surg 22:66-7. 2011
    ....
  40. pmc Inkjet-based biopatterning of bone morphogenetic protein-2 to spatially control calvarial bone formation
    Gregory M Cooper
    Division of Plastic Surgery, Department of Surgery, University of Pittsburgh, Pittsburgh, PA 15224, USA
    Tissue Eng Part A 16:1749-59. 2010
    ..These results demonstrate that three-dimensional biopatterning of a growth factor and growth factor modifier within a construct can direct cell differentiation in vitro and tissue formation in vivo in register to printed patterns...
  41. pmc Age-related peridural hyperemia in craniosynostotic rabbits
    Lesley M Foley
    Pittsburgh NMR Center for Biomedical Research, Carnegie Mellon University, Pittsburgh, PA, USA
    Childs Nerv Syst 25:861-6. 2009
    ..Arterial spin-labeling (ASL) MRI was used to assess regional CBF in developing rabbits with early-onset coronal suture synostosis (EOCS) and age-matched wild-type controls (WT)...
  42. ncbi Repair of oronasal fistulae with acellular dermal matrices
    Richard E Kirschner
    Department of Surgery, Children s Hospital of Philadelphia, Philadelphia, PA 19104 4318, USA
    Plast Reconstr Surg 118:1431-40. 2006
    ..In part I, an animal model was used to demonstrate proof-of-concept; in part II, the method was applied to oronasal fistula repair in the clinical setting...
  43. ncbi Intraoperative high-dose epinephrine infiltration in cleft palate repair
    Christopher R Kinsella
    From the Departments of Plastic Surgery, and Anesthesia, University of Pittsburgh, Pittsburgh, Pennsylvania
    J Craniofac Surg 25:140-2. 2014
    ..In addition, some controversy exists regarding the acceptable dose of epinephrine given to children. This retrospective review examines the use and safety of "high-dose" epinephrine in palatoplasty at our cleft-craniofacial center...
  44. ncbi An algorithm for application of furlow palatoplasty to the treatment of velocardiofacial syndrome-associated velopharyngeal insufficiency
    S Alex Rottgers
    Division of Pediatric Plastic Surgery, The Children s Hospital of Pittsburgh of UPMC, Pittsburgh, PA, USA
    Ann Plast Surg 66:479-84. 2011
    ..Furlow palatoplasty represents a first step in treating appropriate VCFS patients that avoids the risk of sleep apnea, but the potential for secondary pharyngoplasty must be considered...
  45. ncbi Postoperative anti-Tgf-beta2 antibody therapy improves intracranial volume and craniofacial growth in craniosynostotic rabbits
    Mark P Mooney
    Department of Oral Biology, Cleft Palate Craniofacial Center, University of Pittsburgh, and Children s Hospital of Pittsburgh, Pittsburgh, Pennsylvania 15261, USA
    J Craniofac Surg 18:336-46; discussion 347-9. 2007
    ..Thus, this biologically based therapy may be a potential surgical adjunct in the treatment of infants with craniosynostosis...
  46. ncbi The osteogenic potential of adipose-derived stem cells for the repair of rabbit calvarial defects
    Jason R Dudas
    Division of Plastic Surgery, University of Pittsburgh, Pittsburgh, PA, USA
    Ann Plast Surg 56:543-8. 2006
    ..The present study was designed to assess the osteogenic potential and utility of using ASCs to regenerate bone in a rabbit calvarial defect model...
  47. ncbi BMP-4 response in wild-type and craniosynostotic rabbit bone cells
    Gregory M Cooper
    Department of Surgery, Division of Plastic and Reconstructive Surgery, University of Pittsburgh, Pittsburgh, PA, USA
    Plast Reconstr Surg 125:1403-11. 2010
    ..The authors hypothesized that cells derived from suture-associated regions of bone from craniosynostotic rabbits were more osteogenic and proliferative than bone cells derived from wild-type rabbits...
  48. pmc Upper-extremity transplantation using a cell-based protocol to minimize immunosuppression
    Stefan Schneeberger
    Department of Plastic and Reconstructive Surgery, University of Pittsburgh Medical Center, Pittsburgh, PA, USA
    Ann Surg 257:345-51. 2013
    ..To minimize maintenance immunosuppression in upper-extremity transplantation to favor the risk-benefit balance of this procedure...
  49. ncbi Cranial vault remodeling for sagittal craniosynostosis in older children
    S Alex Rottgers
    Children s Hospital of Pittsburgh of UPMC, PA, USA
    Neurosurg Focus 31:E3. 2011
    ....
  50. ncbi Helping hands: caring for the upper extremity transplant patient
    Darlene Lovasik
    UPMC Presbyterian, 200 Lothrop Street, University of Pittsburgh Medical Center, Pittsburgh, PA 15213, USA
    Crit Care Nurs Clin North Am 23:505-17. 2011
    ..The sustained development and research into reliable, reduced-dose immunosuppression or immunomodulatory strategies could expand the life-enhancing benefits of reconstructive transplantation...
  51. pmc Age-related changes in craniofacial morphology in GDF-8 (myostatin)-deficient mice
    Lisa Vecchione
    Pittsburgh Cleft Craniofacial Research Center, University of Pittsburgh, Pittsburgh, Pennsylvania 15261, USA
    Anat Rec (Hoboken) 293:32-41. 2010
    ..These findings reiterate the role that masticatory muscle function plays on the ontogeny of the cranial vault, base, and most notably the mandible...
  52. ncbi Alveolar reconstruction in cleft patients: decreased morbidity and improved outcomes with supplemental demineralized bone matrix and cancellous allograft
    Zoe M Macisaac
    Division of Pediatric Plastic and Reconstructive Surgery, University of Pittsburgh, Pittsburgh, PA 15224, USA
    Plast Reconstr Surg 130:625-32. 2012
    ..The authors report the safety and efficacy of supplemental demineralized bone matrix and cancellous allograft with iliac crest bone autograft in cleft alveolar bone defects...
  53. ncbi Anesthetic management in upper extremity transplantation: the Pittsburgh experience
    R Scott Lang
    Department of Anesthesiology, University of Pittsburgh Medical Center, Pittsburgh, PA 15213, USA
    Anesth Analg 115:678-88. 2012
    ....
  54. ncbi The psychological burden of idiopathic adolescent gynecomastia
    Christopher Kinsella
    Division of Plastic Surgery, Children s Hospital of Pittsburgh, University of Pittsburgh Medical Center, Pittsburgh, PA 15201, USA
    Plast Reconstr Surg 129:1-7. 2012
    ....
  55. ncbi Conversion Furlow palatoplasty: salvage of speech after straight-line palatoplasty and "incomplete intravelar veloplasty"
    Negin Noorchashm
    Division of Pediatric Plastic Surgery, Children s Hospital of Pittsburgh, University of Pittsburgh Medical Center, Pittsburgh, PA 15213, USA
    Ann Plast Surg 56:505-10. 2006
    ..We propose that a conversion Furlow palatoplasty performed with a "complete IVVP" will correct postoperative velopharyngeal insufficiency (VPI) and alleviate the need for pharyngoplasty...
  56. ncbi Diagnosis and treatment of velopharyngeal insufficiency: clinical utility of speech evaluation and videofluoroscopy
    Jason R Dudas
    Division of Plastic Surgery, University of Pittsburgh, Pittsburgh, PA, USA
    Ann Plast Surg 56:511-7; discussion 517. 2006
    ..This study sought to determine whether perceptual speech symptoms were predictive of velopharyngeal closure...
  57. pmc Molecular analysis of coronal perisutural tissues in a craniosynostotic rabbit model using polymerase chain reaction suppression subtractive hybridization
    James J Cray
    Department of Surgery, Division of Plastic and Reconstructive Surgery, University of Pittsburgh and Pediatric Craniofacial Biology Laboratory, Children s Hospital of Pittsburgh, Pittsburgh, PA 15224, USA
    Plast Reconstr Surg 128:95-103. 2011
    ..To understand the pathogenesis of craniosynostosis, the authors compared gene expression in perisutural tissues between wild-type and craniosynostotic rabbits using polymerase chain reaction suppression subtractive hybridization...
  58. ncbi BMP-2-regenerated calvarial bone: a biomechanical appraisal in a large animal model
    James Cray
    From the Departments of Oral Biology, Surgery Plastic Surgery, Orthopaedic Surgery and Orthodontics, Georgia Regents University, Augusta, GA Department of Bioengineering, University of Pittsburgh Center for Craniofacial Regeneration, University of Pittsburgh School of Dental Medicine Department of Plastic Surgery and Craniofacial Biology Laboratory, Children s Hospital of Pittsburgh and University of Pittsburgh, Pittsburgh, PA Department of Surgery, Saint Louis University Hospital, St Louis, MO and Department of Oral Biology, University of Pittsburgh, Pittsburgh, PA
    Ann Plast Surg 73:591-7. 2014
    ..Further investigation is required to assess the efficacy of rhBMP-2 in healing calvarial defects in the longer term...
  59. ncbi Divided parietal bone in plagiocephaly
    Regina A Fenton
    Division of Pediatric Plastic Surgery, Children s Hospital of Pittsburgh of UPMC, University of Pittsburgh, Pittsburgh, PA, USA
    J Craniofac Surg 22:355-8. 2011
    ..Disagreement exists as to how the presence of this suture affects the shape of the skull. We present a case of a supernumerary suture in the parietal bone leading to plagiocephaly and discuss the role this suture plays in cranial growth...
  60. ncbi Management of complex groin wounds: preferred use of the rectus femoris muscle flap
    Joseph D Alkon
    Division of Plastic Surgery, Strong Memorial Hospital, University of Rochester, Rochester, NY, USA
    Plast Reconstr Surg 115:776-83; discussion 784-5. 2005
    ..On the basis of our clinical results, we believe that the rectus femoris muscle flap is the flap of choice for groin wound reconstruction...
  61. ncbi Autologous bone grafting with adjunctive use of acellular dermal matrix for alveolar cleft defects: early outcomes
    Julio A Clavijo-Alvarez
    University of Pittsburgh Medical Center, Pittsburgh, and Children s Hospital of Pittsburgh, PA 15201, USA
    Cleft Palate Craniofac J 47:116-21. 2010
    ..Incorporating acellular dermal matrix into these repairs may protect the bone graft during mucosal healing by providing an additional layer of soft tissue coverage...
  62. ncbi Pediatric facial fractures: occurrence of concussion and relation to fracture patterns
    Paul N Afrooz
    Division of Pediatric Plastic Surgery, Children s Hospital of Pittsburgh, University of Pittsburgh Medical Center, Pittsburgh, Pennsylvania 15201, USA
    J Craniofac Surg 23:1270-3. 2012
    ..The goal of this study was to describe the occurrence of concussion in patients sustaining facial fractures and to determine whether certain fracture types are associated with concussion...
  63. ncbi Human facial allotransplantation: patient selection and pertinent considerations
    Joseph E Losee
    University of Pittsburgh Medical Center, Pittsburgh, Pennsylvania, USA
    J Craniofac Surg 23:260-4. 2012
    ..This article reviews the pertinent considerations and screening approach for appropriate patient selection in facial tissue transplantation...
  64. ncbi Transfusion-free pediatric burn surgery: techniques and strategies
    Joseph E Losee
    Division of Plastic Surgery, Children s Hospital at Strong University of Rochester, Rochester, NY, USA
    Ann Plast Surg 54:165-71. 2005
    ..Large TBSA burns must be surveilled for burn wound anemia that may ultimately require blood transfusion...
  65. ncbi The reverse sural flap: modifications to improve efficacy in foot and ankle reconstruction
    Ahmed M Afifi
    Plastic Surgery, University of Pittsburgh Medical Center, Pittsburgh, Pennsylvania, USA
    Ann Plast Surg 61:430-6. 2008
    ..In addition, we describe the use of tissue expanded sural flaps...
  66. ncbi Severe proliferative congenital temporomandibular joint ankylosis: a proposed treatment protocol utilizing distraction osteogenesis
    Scott P Bartlett
    Division of Plastic Surgery, University of Pennsylvania Medical Center, Pennsylvania 19104, USA
    J Craniofac Surg 17:605-10. 2006
    ..Interim DO, prior to definitive arthroplasty and reconstruction, can provide a static open bite that prevents progressive deformity and its associated functional disturbances...
  67. ncbi A qualitative description of receiving a diagnosis of clefting in the prenatal or postnatal period
    Rachel Nusbaum
    Department of Human Genetics, University of Pittsburgh, Pittsburgh, PA 15219, USA
    J Genet Couns 17:336-50. 2008
    ..Greater awareness of the parental experience of the timing of receiving a cleft diagnosis may assist health care professionals in providing care for these families...
  68. ncbi Favoring the risk-benefit balance for upper extremity transplantation--the Pittsburgh Protocol
    Vijay S Gorantla
    Pittsburgh Reconstructive Transplantation Program, Division of Plastic Surgery, Department of Surgery, 3550 Terrace Street, Pittsburgh, PA 15261, USA
    Hand Clin 27:511-20, ix-x. 2011
    ..Such therapies offer the promise of minimizing the risks, maximizing the benefits and optimizing outcomes of these innovative procedures...
  69. ncbi Transverse lag screw fixation in midline mandibulotomy: a case series revisited
    Joseph M Serletti
    Division of Plastic Surgery, Strong Memorial Hospital, University of Rochester, NY 14642, USA
    Plast Reconstr Surg 114:178-85. 2004
  70. ncbi Age-related changes in lateral ventricle morphology in craniosynostotic rabbits using magnetic resonance imaging
    Wendy Fellows-Mayle
    Department of Neurological Surgery, University of Pittsburgh, PA 15213, USA
    Childs Nerv Syst 21:385-91. 2005
    ..The present study was designed to assess age-related changes in the lateral ventricle volume of the brain in normal rabbits and rabbits with naturally-occurring coronal suture synostosis using serial magnetic resonance imaging...
  71. ncbi Repair of the immature craniofacial skeleton with a calcium phosphate cement: quantitative assessment of craniofacial growth
    Richard E Kirschner
    Division of Plastic Surgery, The Children s Hospital of Philadelphia, PA and the Armed Forces Institute of Pathology, Washington DC, USA
    Ann Plast Surg 49:33-8; discussion 38. 2002
    ..The remodeling capacity of this material offers promise for its safe use in reconstruction of the growing calvarium...
  72. pmc Reconstruction of osteomyelitis defects of the craniofacial skeleton
    Gary E DeCesare
    Division of Pediatric Plastic Surgery, University of Pittsburgh School of Medicine, Pittsburgh, Pennsylvania
    Semin Plast Surg 23:119-31. 2009
    ..Although reconstruction of craniofacial defects after osteomyelitis commonly proves formidable, the satisfactory return of form and function remains a plausible reconstructive goal...
  73. ncbi Temporal soft tissue glioneuronal heterotopia in a child with a seizure disorder: case report and review of the literature
    John A Ozolek
    Department of Pathology, Children s Hospital of Pittsburgh, 3705 Fifth Avenue, Pittsburgh, PA 15213, USA
    Pediatr Dev Pathol 8:673-9. 2005
    ..We speculate that, in certain circumstances, aberrantly localized CNS tissue may be related to abnormal CNS development...
  74. ncbi Primary cutaneous mucormycosis: guide to surgical management
    Joseph E Losee
    Division of Plastic Surgery, University of Rochester, Children s Hospital at Strong, Box 661, 601 Elmwood Avenue, Rochester, NY 14642, USA
    Ann Plast Surg 49:385-90. 2002
    ..In the case of delayed diagnosis and/or advanced or rapidly progressive disease, surgical debridement of all involved tissue, in addition to chemotherapy, is warranted...
  75. ncbi The cleft lateral lip element: do traditional markings result in secondary deformities?
    Joseph E Losee
    Children s Hospital at Strong, Strong Memorial Hospital, University of Rochester, NY 14610, USA
    Ann Plast Surg 50:594-600. 2003
    ..This deformity can be prevented by marking the height of cupid's bow on the cleft lateral lip element just before the attenuation of lip fullness...
  76. ncbi Epignathus teratoma
    Stephen J Vega
    University of Rochester, Rochester, NY, USA
    J Am Coll Surg 197:332-3. 2003