Research Topics
| B P LanphearSummaryAffiliation: Children's Hospital Medical Center Country: USA Publications
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Detail Information
Publications
Long-term effect of dust control on blood lead concentrationsB P Lanphear
Children s Hospital Medical Center, Cincinnati Ohio 45229 3039, USA
Pediatrics 106:E48. 2000..Dust control is recommended to prevent children's exposure to residential lead hazards, but the long-term effect of dust control on children's exposure to environmental lead is unknown...- Prevention of lead toxicity in US childrenBruce P Lanphear
Cincinnati Children s Environmental Health Center, Department of Pediatrics, Children s Hospital Medical Center, Ohio 45229, USA
Ambul Pediatr 3:27-36. 2003..This article reviews the epidemiology and control of childhood lead exposure, focusing especially on steps necessary to shift toward primary prevention... - Biomarkers in paediatric research and practiceB P Lanphear
Cincinnati Children s Environmental Health Center, Cincinnati Children s Hospital Medical Center, Department of Pediatrics, University of Cincinnati, Cincinnati, Ohio, USA
Arch Dis Child 90:594-600. 2005..Our understanding of the risk factors for many diseases is incomplete, but it is widely recognised that disability and death result largely from interactions of environmental factors, broadly defined, and host susceptibility... - Screening housing to prevent lead toxicity in childrenBruce P Lanphear
Cincinnati Children s Environmental Health Center, Children s Hospital Medical Center, Cincinnati, OH 45229 3039, USA
Public Health Rep 120:305-10. 2005..The purpose of this study was to identify and validate housing characteristics associated with children having elevated blood lead levels (> or = 10 microg/dl)... - Contribution of residential exposures to asthma in us children and adolescentsB P Lanphear
Children s Hospital Medical Center, Cincinnati, Ohio, USA
Pediatrics 107:E98. 2001..Residential exposures are recognized risk factors for asthma, but the relative contribution of specific indoor allergens and their overall contribution to asthma among older children and adolescents in the United States are unknown... - Cognitive deficits associated with blood lead concentrations <10 microg/dL in US children and adolescentsB P Lanphear
Children s Hospital Medical Center, Cincinnati, Ohio 45229, USA
Public Health Rep 115:521-9. 2000.... - Residential exposures associated with asthma in US childrenB P Lanphear
Children s Hospital Medical Center, Cincinnati, Ohio 45229 3039, USA
Pediatrics 107:505-11. 2001..The objective of this study was to identify risk factors and estimate the population attributable risk of residential exposures for doctor-diagnosed asthma for US children... - The effect of soil abatement on blood lead levels in children living near a former smelting and milling operationBruce P Lanphear
Cincinnati Children s Environmental Health Center, Children s Hospital Medical Center, OH 45229, USA
Public Health Rep 118:83-91. 2003..To evaluate the effect of soil abatement on children's blood lead concentrations and on environmental levels of lead and arsenic... - Trials and tribulations of protecting children from environmental hazardsBruce P Lanphear
Cincinnati Children s Environmental Health Center, Cincinnati Children s Hospital Medical Center, Department of Pediatrics, University of Cincinnati, Cincinnati, Ohio 45229 3039, USA
Environ Health Perspect 114:1609-12. 2006.... - Environmental exposures to lead and urban children's blood lead levelsB P Lanphear
Department of Pediatrics, University of Rochester School of Medicine and Dentistry, New York, USA
Environ Res 76:120-30. 1998..These data support the promulgation of health-based standards for lead-contaminated dust and soil and the progressive lowering of standards for lead-contaminated water as the definition of undue lead exposure has been modified... - Risk factors for the early acquisition of human herpesvirus 6 and human herpesvirus 7 infections in childrenB P Lanphear
Children s Hospital Medical Center and the Department of Pediatrics, University of Cincinnati, OH 45229 3039, USA
Pediatr Infect Dis J 17:792-5. 1998..Human herpesviruses 6 and 7 (HHV-6 and HHV-7) are common infections in children, but risk factors for their early acquisition have not been described... - Pathways of lead exposure in urban childrenB P Lanphear
Department of Pediatrics, University of Rochester School of Medicine and Dentistry, New York, USA
Environ Res 74:67-73. 1997.... - A side-by-side comparison of sampling methods for settled, indoor allergensM Mansour
Cincinnati Lead and Allergen Sampling Study with Children's Hospital Medical Center, Department of Pediatrics, Ohio 45229, USA
Environ Res 87:37-46. 2001..In general, cat allergen collected with the Cyclone was a better predictor of serum-specific IgE levels to Fel d I, whereas dust mite allergen collected with the Readivac II was a better predictor of serum-specific IgE levels to Der f I... - Childhood injuries and deaths due to falls from windowsK E Stone
Children s Hospital Medical Center, Cincinnati, Ohio, USA
J Urban Health 77:26-33. 2000..The incidence of falls from windows, a common cause of death in urban areas, has not been described outside major cities such as New York and Chicago, and rates in urban and suburban areas have not been compared... - Proton magnetic resonance spectroscopy in adults with childhood lead exposureKim M Cecil
Cincinnati Children s Environmental Health Center at Cincinnati Children s Hospital Medical Center, Ohio 45229, USA
Environ Health Perspect 119:403-8. 2011..Childhood lead exposure adversely affects neurodevelopment. However, few studies have examined changes in human brain metabolism that may underlie known adverse cognitive and behavioral outcomes... - Vitamin D receptor Fok1 polymorphism and blood lead concentration in childrenErin N Haynes
Cincinnati Children s Environmental Health Center and General and Community Pediatrics, Cincinnati Children s Hospital Medical Center, and Department of Environmental Health, University of Cincinnati, Cincinnati, Ohio, USA
Environ Health Perspect 111:1665-9. 2003..These data suggest that VDR -Fok1 is an effect modifier of the relationship of floor dust lead exposure and blood lead concentration... - Reporting individual test results of environmental chemicals in breastmilk: potential for premature weaningSheela R Geraghty
Division of General and Community Pediatrics, Cincinnati Children s Hospital Medical Center, University of Cincinnati, Cincinnati, Ohio 45229 3039, USA
Breastfeed Med 3:207-13. 2008..The purpose of this study was to determine if mothers want to know if chemicals are in their breastmilk and if knowing the results would alter their breastfeeding practices... - Milk intake during childhood and adolescence, adult bone density, and osteoporotic fractures in US womenHeidi J Kalkwarf
Division of General and Community Pediatrics, Children s Hospital Medical Center, Cincinnati, OH 45229 3039, USA
Am J Clin Nutr 77:257-65. 2003..Calcium supplements increase bone mass in children, but the effect does not persist once supplementation is discontinued... - Environmental neurotoxinsBruce P Lanphear
Department of Pediatrics, Cincinnati Children's Environmental Health Center, Cincinnati Children's Hospital, Medical Center University of Cincinnati, Cincinnati, Ohio, USA
Pediatr Rev 26:191-7; quiz 198. 2005 - Low-level environmental lead exposure and children's intellectual function: an international pooled analysisBruce P Lanphear
Cincinnati Children s Hospital Medical Center, Cincinnati, Ohio 45229 3039, USA
Environ Health Perspect 113:894-9. 2005..5 microg/dL (p = 0.015). We conclude that environmental lead exposure in children who have maximal blood lead levels < 7.5 microg/dL is associated with intellectual deficits... - Barriers to asthma care in urban children: parent perspectivesM E Mansour
Children s Hospital Medical Center and the Department of Pediatrics, University of Cincinnati, Cincinnati, Ohio 45229 3039, USA
Pediatrics 106:512-9. 2000..Despite improved treatment regimens for asthma, the prevalence and morbidity from asthma are increasing, especially among underserved, minority children... - Trends and patterns of playground injuries in United States children and adolescentsK J Phelan
Department of Pediatrics, Children s Hospital Medical Center, Cincinnati, OH 45229, USA
Ambul Pediatr 1:227-33. 2001..To determine the prevalence, trends, and severity of injuries attributable to playground falls relative to other common unintentional mechanisms that resulted in an emergency department (ED) visit in the United States... - Association of tobacco and lead exposures with attention-deficit/hyperactivity disorderTanya E Froehlich
Department of Pediatrics, Cincinnati Children s Hospital Medical Center, University of Cincinnati College of Medicine, Cincinnati, Ohio 45229, USA
Pediatrics 124:e1054-63. 2009.... - Protecting children from environmental toxinsBruce P Lanphear
Environmental Health Center at Cincinnati Children's Hospital Medical Center, Ohio, USA
PLoS Med 2:e61. 2005 - Decreased brain volume in adults with childhood lead exposureKim M Cecil
Cincinnati Children s Environmental Health Center, Cincinnati Children s Hospital Medical Center, Cincinnati, Ohio, United States of America
PLoS Med 5:e112. 2008..In this study, we examined the relationship between childhood lead exposure and adult brain volume using magnetic resonance imaging (MRI). We also explored how volume changes correlate with historic neuropsychological assessments... - The impact of early childhood lead exposure on brain organization: a functional magnetic resonance imaging study of language functionWeihong Yuan
Department of Radiology, Cincinnati Children's Hospital Medical Center, Cincinnati, Ohio, USA
Pediatrics 118:971-7. 2006..CONCLUSION: This study indicates that childhood lead exposure has a significant and persistent impact on brain reorganization associated with language function... - Environmental lead exposure during early childhoodBruce P Lanphear
General and Community Pediatrics Department, Children's Hospital Medical Center, Cincinnati, OH 45229, USA
J Pediatr 140:40-7. 2002..Black children remain at increased risk for higher blood lead concentration after adjusting for environmental lead exposures and dietary intake... - Physiologic stability of newborns during cup- and bottle-feedingC R Howard
Department of Pediatrics, University of Rochester School of Medicine and Dentistry, Rochester, New York, USA
Pediatrics 104:1204-7. 1999..To prevent breastfeeding problems, cup-feeding has been recommended as a method of providing medically necessary supplemental feedings to breastfed infants... - Altered myelination and axonal integrity in adults with childhood lead exposure: a diffusion tensor imaging studyChristopher J Brubaker
Cincinnati Children s Environmental Health Center at the Cincinnati Children s Hospital Medical Center, University of Cincinnati College of Medicine, Cincinnati, OH 45229, USA
Neurotoxicology 30:867-75. 2009..This study indicates that childhood lead exposure is associated with a significant and persistent impact on white matter microstructure as quantified with diffusivity changes suggestive of altered myelination and axonal integrity... - Interactive effects of a DRD4 polymorphism, lead, and sex on executive functions in childrenTanya E Froehlich
Department of Pediatrics, University of Cincinnati College of Medicine, Cincinnati, Ohio, USA
Biol Psychiatry 62:243-9. 2007..Prior studies have examined independent effects of a dopamine receptor D4 polymorphism (DRD4-7) and lead exposure on executive functions but not their interaction or the role of sex as a modifier of their effects... - The conundrum of unmeasured confounding: Comment on: "Can some of the detrimental neurodevelopmental effects attributed to lead be due to pesticides? by Brian Gulson"Bruce P Lanphear
Cincinnati Children s Environmental Health Center, Department of Pediatrics and of Environmental Health, Cincinnati Children s Hospital Medical Center, The University of Cincinnati, Cincinnati, Ohio, USA
Sci Total Environ 396:196-200. 2008..The alternative, to perpetually permit children to be exposed to lead and other emerging toxicants, is both absurd and unacceptable... - Association of prenatal and childhood blood lead concentrations with criminal arrests in early adulthoodJohn Paul Wright
Cincinnati Children s Environmental Health Center, Division of Criminal Justice, University of Cincinnati, Cincinnati, Ohio, United States of America
PLoS Med 5:e101. 2008..The objective of this study was to determine if prenatal and childhood blood lead concentrations are associated with arrests for criminal offenses... - Environmental exposures and exhaled nitric oxide in children with asthmaAdam J Spanier
Cincinnati Children s Environmental Health Center, Division of General and Community Pediatrics, and the Division of Allergy and Clinical Immunology, Cincinnati Children s Hospital Medical Center, Cincinnati, Ohio, USA
J Pediatr 149:220-6. 2006..To evaluate the relation of environmental factors with exhaled nitric oxide (FENO) concentrations among asthmatic children... - Age of greatest susceptibility to childhood lead exposure: a new statistical approachRichard W Hornung
Cincinnati Children s Environmental Health Center, Cincinnati Children s Hospital Medical Center, Cincinnati, Ohio 45229 3039, USA
Environ Health Perspect 117:1309-12. 2009..Susceptibility to lead toxicity is often assumed to be greatest during early childhood (e.g., 2 years of age), but recent studies suggest that blood lead concentrations (BPb) taken at 5-7 years of age are more strongly associated with IQ... - Racial differences in exposure to environmental tobacco smoke among childrenStephen E Wilson
Division of General Internal Medicine, University of Cincinnati, Cincinnati, Ohio, USA
Environ Health Perspect 113:362-7. 2005..Identifying causes and consequences of increased cotinine may help explain the striking differences in tobacco-related illnesses... - The influence of age of lead exposure on adult gray matter volumeChristopher J Brubaker
Cincinnati Children s Environmental Health Center, Cincinnati Children s Hospital Medical Center, University of Cincinnati College of Medicine, Cincinnati, OH, USA
Neurotoxicology 31:259-66. 2010..This study demonstrates that maximum blood lead levels do not fully account for gray matter changes associated with childhood lead exposure, particularly in the frontal lobes of young men... - Trends in otitis media among children in the United StatesPeggy Auinger
Department of Pediatrics, University of Rochester School of Medicine and Dentistry and the American Academy of Pediatrics Center for Child Health Research, Rochester, New York 14620, USA
Pediatrics 112:514-20. 2003..The prevalence of repeated otitis media (OM) increased during the 1980s, but it is unknown if the increase has continued... - Environmental exposures, nitric oxide synthase genes, and exhaled nitric oxide in asthmatic childrenAdam J Spanier
Cincinnati Children s Environmental Health Center, Cincinnati Children s Hospital Medical Center, Cincinnati, Ohio, USA
Pediatr Pulmonol 44:812-9. 2009..We conclude that genetic differences may explain some of the conflicting results in studies of the effects of tobacco smoke exposure on FeNO levels and may make FeNO interpretation difficult for a subset of children with asthma... - Seasonal variation and environmental predictors of exhaled nitric oxide in children with asthmaAdam J Spanier
Cincinnati Children s Environmental Health Center, Cincinnati Children s Hospital Medical Center, Cincinnati, Ohio 45229 3039, USA
Pediatr Pulmonol 43:576-83. 2008..Clinicians and researchers may need to consider an individual's baseline FeNO levels to manage children with asthma... - Role of dopamine transporter genotype and maternal prenatal smoking in childhood hyperactive-impulsive, inattentive, and oppositional behaviorsRobert S Kahn
Division of General and Community Pediatrics, and Children s Environmental Health Center, Cincinnati Children s Hospital Medical Center, Cincinnati, Ohio 45229 3039, USA
J Pediatr 143:104-10. 2003..To examine the joint effects of a dopamine transporter (DAT) polymorphism and maternal prenatal smoking on childhood hyperactivity-impulsivity and inattentiveness... - Exposure to environmental tobacco smoke and cognitive abilities among U.S. children and adolescentsKimberly Yolton
Cincinnati Children s Environmental Health Center, Department of Pediatrics, Cincinnati Children s Hospital Medical Center, Cincinnati, Ohio 45229 3039, USA
Environ Health Perspect 113:98-103. 2005..These data, which indicate an inverse association between ETS exposure and cognitive deficits among children even at extremely low levels of exposure, support policy to further restrict children's exposure... - Prevalence, recognition, and treatment of attention-deficit/hyperactivity disorder in a national sample of US childrenTanya E Froehlich
Cincinnati Children s Hospital Medical Center, Cincinnati, OH 45229, USA
Arch Pediatr Adolesc Med 161:857-64. 2007..To determine the US national prevalence of attention-deficit/hyperactivity disorder (ADHD) and whether prevalence, recognition, and treatment vary by socioeconomic group... - Parental responses to infant crying and colic: the effect on breastfeeding durationCynthia R Howard
Department of Pediatrics, The University of Rochester School of Medicine and Dentistry, Rochester, New York 14621, USA
Breastfeed Med 1:146-55. 2006..Breastfeeding is recognized as an effective method of calming infants, but the relationship of colic and the use of breastfeeding to remedy infant crying have not been tested for any effects on breastfeeding duration... - The role of air nicotine in explaining racial differences in cotinine among tobacco-exposed childrenStephen E Wilson
University of Cincinnati, 231 Albert Sabin Way, Room 6603, Cincinnati, OH 45267, USA
Chest 131:856-62. 2007..The objective of this study was to test whether African-American children have higher levels of cotinine compared to white children while accounting for ambient measures of tobacco smoke... - Association of environmental toxicants and conduct disorder in U.S. children: NHANES 2001-2004Joseph M Braun
Department of Epidemiology, University of North Carolina Chapel Hill, Chapel Hill, NC 27599 7435, USA
Environ Health Perspect 116:956-62. 2008..The purpose of this study was to examine the association of tobacco smoke and environmental lead exposure with conduct disorder (CD)... - The conquest of lead poisoning: a Pyrrhic victoryBruce P Lanphear
Environ Health Perspect 115:A484-5. 2007 - The effects of housing interventions on child healthMegan Sandel
Boston University Medical School, Boston, MA, USA
Pediatr Ann 33:474-81. 2004..With research in more effective environmental interventions and pediatric-public-health partnerships, primary and secondary prevention of diseases from residential hazards may become a reality in the future... - The effect of interior lead hazard controls on children's blood lead concentrations: a systematic evaluationErin Haynes
University of Michigan School of Public Health, Ann Arbor, Michigan, USA
Environ Health Perspect 110:103-7. 2002.... - Intellectual impairment in children with blood lead concentrations below 10 microg per deciliterRichard L Canfield
Division of Nutritional Sciences, College of Human Ecology, Cornell University, Ithaca, NY 14853, USA
N Engl J Med 348:1517-26. 2003..483 micromol per liter), little is known about children's neurobehavioral functioning at lead concentrations below this level... - Exposures to environmental toxicants and attention deficit hyperactivity disorder in U.S. childrenJoe M Braun
College of Nursing, University of Wisconsin-Milwaukee, Milwaukee, Wisconsin, USA
Environ Health Perspect 114:1904-9. 2006..S. children. CONCLUSIONS: We conclude that exposure to prenatal tobacco and environmental lead are risk factors for ADHD in U.S. children... - Human health risks from low-level environmental exposures: no apparent safety thresholdsDonald T Wigle
McLaughlin Centre for Population Health Risk Assessment, Institute of Population Health, University of Ottawa, Ottawa, Canada
PLoS Med 2:e350. 2005 - Childhood lead poisoning prevention: too little, too lateBruce P Lanphear
JAMA 293:2274-6. 2005 - Comments on "Recent developments in low-level lead exposure and intellectual impairment in children"Todd A Jusko
Environ Health Perspect 113:A16; author reply A16-7. 2005 - Blood lead concentrations < 10 microg/dL and child intelligence at 6 years of ageTodd A Jusko
Department of Epidemiology, School of Public Health and Community Medicine, University of Washington, Seattle, WA, USA
Environ Health Perspect 116:243-8. 2008..Few studies provide data directly relevant to the question of whether blood lead concentrations < 10 microg/dL adversely affect children's cognitive function...