H F Krous

Summary

Affiliation: Children's Hospital and Health Center
Country: USA

Publications

  1. ncbi request reprint Laryngeal basement membrane thickening is not a reliable postmortem marker for SIDS: results from the Chicago Infant Mortality Study
    H F Krous
    Children s Hospital San Diego, California 92123, USA
    Am J Forensic Med Pathol 20:221-7. 1999
  2. ncbi request reprint Sudden death in toddlers with viral meningitis, massive cerebral edema, and neurogenic pulmonary edema and hemorrhage: report of two cases
    Henry F Krous
    Department of Pathology, Rady Children s Hospital San Diego, San Diego, CA, USA
    Pediatr Dev Pathol 10:463-9. 2007
  3. ncbi request reprint Tumors associated with sudden infant and childhood death
    Henry F Krous
    Children s Hospital and Health Center, 3020 Children s Way, MC5007, San Diego, CA 92123, USA
    Pediatr Dev Pathol 8:20-5. 2005
  4. ncbi request reprint Delayed infant death following catastrophic deterioration during breast-feeding
    Henry F Krous
    Children s Hospital and Health Center, San Diego County, California 92123, USA
    J Paediatr Child Health 41:215-7. 2005
  5. ncbi request reprint Sudden unexpected death in childhood: a report of 50 cases
    Henry F Krous
    Department of Pathology, Children s Hospital and Health Center, San Diego, CA 92123, USA
    Pediatr Dev Pathol 8:307-19. 2005
  6. ncbi request reprint Sudden death in a neonate with idiopathic eosinophilic endomyocarditis
    Henry F Krous
    Children s Hospital and Health Center, 3020 Children s Way, MC5007, San Diego, California 92123, USA
    Pediatr Dev Pathol 8:587-92. 2005
  7. ncbi request reprint Child Protective Services referrals in cases of sudden infant death: a 10-year, population-based analysis in San Diego County, California
    Henry F Krous
    Children s Hospital, San Diego, CA 92123, USA
    Child Maltreat 11:247-56. 2006
  8. ncbi request reprint Hemoglobin F in sudden infant death syndrome: a San Diego SIDS/SUDC Research Project report
    Henry F Krous
    Rady Children s Hospital and Health Center, 3020 Children s Way, MC5007, San Diego, CA 92123, USA
    J Forensic Leg Med 14:456-60. 2007
  9. ncbi request reprint Nephrogenic systemic fibrosis with multiorgan involvement in a teenage male after lymphoma, Ewing's sarcoma, end-stage renal disease, and hemodialysis
    Henry F Krous
    Pathology Department, Rady Children s Hospital San Diego, San Diego, CA, USA
    Pediatr Dev Pathol 10:395-402. 2007
  10. ncbi request reprint Pulmonary intra-alveolar siderophages in SIDS and suffocation: a San Diego SIDS/SUDC Research Project report
    Henry F Krous
    Department of Pathology, Children s Hospital and Health Center, 3020 Children s Way, MC5007, San Diego, CA 92123, USA
    Pediatr Dev Pathol 9:103-14. 2006

Collaborators

Detail Information

Publications51

  1. ncbi request reprint Laryngeal basement membrane thickening is not a reliable postmortem marker for SIDS: results from the Chicago Infant Mortality Study
    H F Krous
    Children s Hospital San Diego, California 92123, USA
    Am J Forensic Med Pathol 20:221-7. 1999
    ..Therefore, LBMT should not be used to diagnose SIDS...
  2. ncbi request reprint Sudden death in toddlers with viral meningitis, massive cerebral edema, and neurogenic pulmonary edema and hemorrhage: report of two cases
    Henry F Krous
    Department of Pathology, Rady Children s Hospital San Diego, San Diego, CA, USA
    Pediatr Dev Pathol 10:463-9. 2007
    ..They also underscore the importance of a comprehensive autopsy, including detailed neuropathologic examination and viral testing, in determining of the cause of unexpected death in toddlers...
  3. ncbi request reprint Tumors associated with sudden infant and childhood death
    Henry F Krous
    Children s Hospital and Health Center, 3020 Children s Way, MC5007, San Diego, CA 92123, USA
    Pediatr Dev Pathol 8:20-5. 2005
    ..The diagnosis of these lesions can be established only after thorough postmortem examination...
  4. ncbi request reprint Delayed infant death following catastrophic deterioration during breast-feeding
    Henry F Krous
    Children s Hospital and Health Center, San Diego County, California 92123, USA
    J Paediatr Child Health 41:215-7. 2005
  5. ncbi request reprint Sudden unexpected death in childhood: a report of 50 cases
    Henry F Krous
    Department of Pathology, Children s Hospital and Health Center, San Diego, CA 92123, USA
    Pediatr Dev Pathol 8:307-19. 2005
    ..Legislation enabling research and formation of a multicenter research team is recommended to unravel the mystery of SUDC...
  6. ncbi request reprint Sudden death in a neonate with idiopathic eosinophilic endomyocarditis
    Henry F Krous
    Children s Hospital and Health Center, 3020 Children s Way, MC5007, San Diego, California 92123, USA
    Pediatr Dev Pathol 8:587-92. 2005
    ..The medical literature is reviewed...
  7. ncbi request reprint Child Protective Services referrals in cases of sudden infant death: a 10-year, population-based analysis in San Diego County, California
    Henry F Krous
    Children s Hospital, San Diego, CA 92123, USA
    Child Maltreat 11:247-56. 2006
    ....
  8. ncbi request reprint Hemoglobin F in sudden infant death syndrome: a San Diego SIDS/SUDC Research Project report
    Henry F Krous
    Rady Children s Hospital and Health Center, 3020 Children s Way, MC5007, San Diego, CA 92123, USA
    J Forensic Leg Med 14:456-60. 2007
    ..Given that our results were obtained using optimal methods in well-defined SIDS and control cases, we concur with others that %HbF is not elevated in SIDS...
  9. ncbi request reprint Nephrogenic systemic fibrosis with multiorgan involvement in a teenage male after lymphoma, Ewing's sarcoma, end-stage renal disease, and hemodialysis
    Henry F Krous
    Pathology Department, Rady Children s Hospital San Diego, San Diego, CA, USA
    Pediatr Dev Pathol 10:395-402. 2007
    ..These previously unreported findings expand the spectrum of multiorgan involvement in NSF providing additional evidence that it is an emerging systemic disorder...
  10. ncbi request reprint Pulmonary intra-alveolar siderophages in SIDS and suffocation: a San Diego SIDS/SUDC Research Project report
    Henry F Krous
    Department of Pathology, Children s Hospital and Health Center, 3020 Children s Way, MC5007, San Diego, CA 92123, USA
    Pediatr Dev Pathol 9:103-14. 2006
    ..The number of PS varies widely in cases of sudden infant death caused by SIDS and accidental or inflicted suffocation and cannot be used as an independent variable to ascertain past attempts at suffocation...
  11. ncbi request reprint Aspiration of gastric contents in sudden infant death syndrome without cardiopulmonary resuscitation
    Henry F Krous
    Department of Pathology, Rady Children s Hospital, San Diego, California 92123, USA
    J Pediatr 150:241-6. 2007
    ....
  12. ncbi request reprint Pulmonary intra-alveolar hemorrhage in SIDS and suffocation
    Henry F Krous
    Department of Pathology, Rady Children s Hospital, San Diego, CA, USA
    J Forensic Leg Med 14:461-70. 2007
    ..We conclude that each case must be evaluated on its own merits after thorough review of the medical history, circumstances of death, and postmortem findings...
  13. ncbi request reprint Congenital cerebellar malignant rhabdoid tumor in an infant with junctional epidermolysis bullosa
    Henry F Krous
    Department of Pathology, Rady Children s Hospital and Health Center, San Diego, CA, USA
    Pediatr Dev Pathol 10:481-6. 2007
    ..Cytogenetic results from the infant and his tumor and both of his parents suggest the infant's EB and MRT were not genetically linked...
  14. ncbi request reprint A comparison of pulmonary intra-alveolar hemorrhage in cases of sudden infant death due to SIDS in a safe sleep environment or to suffocation
    Henry F Krous
    Department of Pathology, Rady Children s Hospital San Diego, 3020 Children s Way, MC5007, San Diego, CA 92123, USA
    Forensic Sci Int 172:56-62. 2007
    ..Each case must be evaluated on its own merits after thorough review of the medical history, circumstances of death, and postmortem findings...
  15. ncbi request reprint Medial smooth muscle thickness in small pulmonary arteries in sudden infant death syndrome revisited
    Henry F Krous
    Department of Pathology, Children s Hospital San Diego, 3020 Children s Way, MC5007, San Diego, CA 92123, USA
    Pediatr Dev Pathol 5:375-85. 2002
    ....
  16. ncbi request reprint Pathology research into sudden infant death syndrome: where do we go from here?
    Henry F Krous
    Children s Hospital and Health Center, 3020 Children s Way, M5007, San Diego, CA 92123, USA
    Pediatrics 114:492-4. 2004
  17. ncbi request reprint A comparison of respiratory symptoms and inflammation in sudden infant death syndrome and in accidental or inflicted infant death
    Henry F Krous
    Department of Pathology, Children s Hospital San Diego, San Diego, CA 92123, USA
    Am J Forensic Med Pathol 24:1-8. 2003
    ..Among control cases, 89% were positive, with 94% being polymicrobial. This study confirms that microscopic inflammatory infiltrates in sudden infant death syndrome are not lethal...
  18. ncbi request reprint Environmental hyperthermic infant and early childhood death: circumstances, pathologic changes, and manner of death
    H F Krous
    Children s Hospital San Diego, CA 92123, USA
    Am J Forensic Med Pathol 22:374-82. 2001
    ..The manner of death was either accident or homicide. Recommendations for the scene investigation are made...
  19. ncbi request reprint Oronasal blood in sudden infant death
    H F Krous
    Children s Hospital San Diego, CA 92123, USA
    Am J Forensic Med Pathol 22:346-51. 2001
    ..Sanguineous secretions that are mucoid or frothy are likely of remote origin, such as lung alveoli. The use of an otoscope to establish the origin of oronasal blood in cases of sudden infant death is recommended...
  20. ncbi request reprint Cystic fibrosis--another cause of nodular glomerulosclerosis
    Henry F Krous
    Department of Pathology and Pediatrics, Children s Hospital and Health Center, University of California, San Diego School of Medicine, San Diego, Calif 92123, USA
    Nephron Clin Pract 96:c67-9. 2004
  21. ncbi request reprint Sudden infant death syndrome and unclassified sudden infant deaths: a definitional and diagnostic approach
    Henry F Krous
    Department of Pathology, Children s Hospital San Diego, University of California, San Diego, School of Medicine, San Diego, California 92123, USA
    Pediatrics 114:234-8. 2004
    ..It is anticipated that these new definitions will be modified in the future to accommodate new understanding of SIDS and sudden infant death...
  22. ncbi request reprint Infanticide: is its incidence among postneonatal infant deaths increasing?: an 18-year population-based analysis in California
    Henry F Krous
    Department of Pathology, Children s Hospital San Diego, 92123, USA
    Am J Forensic Med Pathol 23:127-31. 2002
    ..2%. It is concluded that this increased percentage is due to a decrease in SIDS deaths and not to an actual increase in infanticide deaths...
  23. ncbi request reprint Delayed death in sudden infant death syndrome: a San Diego SIDS/SUDC Research Project 15-year population-based report
    Henry F Krous
    Rady Children s Hospital and Health Center, San Diego, CA 92123, USA
    Forensic Sci Int 176:209-16. 2008
    ..We did not identify factors that would reliably predict which SIDS cases might be discovered soon enough to allow earlier and more effective CPR and survival without permanent brain injury...
  24. ncbi request reprint Unclassified sudden infant death associated with pulmonary intra-alveolar hemosiderosis and hemorrhage
    Homeyra Masoumi
    Department of Pathology, Rady Children s Hospital and Health Center, 3020 Children s Way, MC5007, San Diego, CA 92123, USA
    J Forensic Leg Med 14:471-4. 2007
    ....
  25. doi request reprint Intrathoracic petechiae in SIDS: a retrospective population-based 15-year study
    Henry F Krous
    Rady Children s Hospital San Diego, 3020 Children s Way, M5007, San Diego, CA 92123, USA
    Forensic Sci Med Pathol 4:234-9. 2008
    ..Our data do not support a role for external UAO caused by face positioning directly into the sleep surface in SIDS, but are consistent with internal UAO associated with apnea or gasping before dying of SIDS...
  26. pmc Pulmonary arterial medial smooth muscle thickness in sudden infant death syndrome: an analysis of subsets of 73 cases
    Henry F Krous
    Department of Pathology, Rady Children s Hospital San Diego, CA 92123, USA
    Forensic Sci Med Pathol 5:261-8. 2009
    ..Statistical differences should not necessarily be equated with clinical importance, however future research incorporating more quantified historical data is recommended...
  27. doi request reprint Sudden infant death while awake
    Henry F Krous
    Department of Pathology, Rady Children s Hospital and Health Center, 3020 Children s Way, MC5007, San Diego, CA 92123, USA
    Forensic Sci Med Pathol 4:40-6. 2008
    ..Careful attention should be given to the awake or sleep state immediately prior to the sudden clinical collapse, and death of infants; those who were awake should be reported to enhance understanding of this phenomenon...
  28. pmc Brainstem serotonergic deficiency in sudden infant death syndrome
    Jhodie R Duncan
    Department of Pathology, Children s Hospital Boston, 300 Longwood Ave, Boston, MA 02115, USA
    JAMA 303:430-7. 2010
    ..Abnormalities of serotonin (5-hydroxytryptamine [5-HT]) receptor binding in regions of the medulla oblongata involved in this control have been reported in infants dying from SIDS...
  29. ncbi request reprint Sudden death in toddlers associated with developmental abnormalities of the hippocampus: a report of five cases
    Hannah C Kinney
    Department of Pathology, Children s Hospital and Harvard Medical School, Boston, MA, USA
    Pediatr Dev Pathol 10:208-23. 2007
    ..Future studies are needed to confirm these initial findings and to define the putative links between sudden death, hippocampal anomalies, and febrile seizures in toddlers...
  30. ncbi request reprint Sudden, unexpected death associated with meningioangiomatosis: case report
    Chris Wixom
    Children s Hospital and Health Center, 3020 Children s Way, MC5007, San Diego, CA 92123, USA
    Pediatr Dev Pathol 8:240-4. 2005
    ..Because no other cause of death was found, we postulate that he likely died as a result of a seizure secondary to meningioangiomatosis...
  31. doi request reprint Myocardial inflammation, cellular death, and viral detection in sudden infant death caused by SIDS, suffocation, or myocarditis
    Henry F Krous
    Department of Pathology, University of California San Diego, La Jolla, CA 92037, USA
    Pediatr Res 66:17-21. 2009
    ..Very mild myocardial lymphocyte and macrophage infiltration and scattered necrotic cardiomyocytes in SIDS are not pathologic, but may occur after the developing heart is exposed to environmental pathogens, including viruses...
  32. ncbi request reprint Meadow, Southall, and the General Medical Council of the United kingdom
    David L Chadwick
    Chadwick Center for Children and Families, Children s Hospital San Diego, CA 91941, USA
    Pediatrics 117:2247-51. 2006
    ..Licensing boards may have difficulty in competently regulating doctors' expert testimony, at least in cases involving child maltreatment...
  33. doi request reprint Sudden death in a toddler with laryngotracheitis caused by human parainfluenza virus-1
    Jonathan R Lucas
    Office of the Medical Examiner, San Diego, CA, USA
    Pediatr Dev Pathol 12:165-8. 2009
    ....
  34. ncbi request reprint Autoinfarcted wandering spleen and fatal pneumococcal sepsis in an infant
    Eric A Breisch
    Department of Pathology, Children s Hospital and Health Center, 3020 Children s Way, M5007, San Diego, CA 92123, USA
    Pediatr Dev Pathol 8:132-5. 2005
    ..The wandering spleen was autoinfarcted and adherent to the left hepatic lobe, with resultant functional hyposplenism...
  35. ncbi request reprint The role of the pediatric pathologist as expert witness in a case of neonatal death
    Henry F Krous
    Rady Children s Hospital San Diego, San Diego, CA, USA
    Pediatr Dev Pathol 11:200-5. 2008
    ..We discuss U.S. Supreme Court rulings pertaining to medical expert testimony and identify remedies to increase just outcomes in cases of medical malpractice...
  36. doi request reprint Sudden unexpected death in a toddler with Williams syndrome
    Henry F Krous
    Rady Children s Hospital and Health Center, 3020 Children s Way, MC5007, San Diego, CA 92123, USA
    Forensic Sci Med Pathol 4:240-5. 2008
    ..The cardiovascular anomalies and their association with sudden death as well as the clinical neurological and neuropathologic abnormalities identified in WS are delineated and discussed...
  37. ncbi request reprint Sudden unexpected death in childhood associated with cardiac rhabdomyoma, involuting adrenal ganglioneuroma, and megalencephaly: another expression of tuberous sclerosis?
    Homeyra Masoumi
    Rady Children s Hospital and Health Center, San Diego, CA, USA
    Pediatr Dev Pathol 10:129-33. 2007
    ..The constellation of her autopsy findings suggested a diagnosis of tuberous sclerosis, for which there are gene defects that can be identified in surviving family members...
  38. pmc Serotonin-related FEV gene variant in the sudden infant death syndrome is a common polymorphism in the African-American population
    Kevin G Broadbelt
    Department of Pathology, Enders Building Room 1111, Children s Hospital Boston, 300 Longwood Avenue, Boston, MA 02115, USA
    Pediatr Res 66:631-5. 2009
    ..128-(191_192)dupA). The polymorphism seems to be a common, likely nonpathogenic, variant in the African-American population...
  39. ncbi request reprint Multiple serotonergic brainstem abnormalities in sudden infant death syndrome
    David S Paterson
    Department of Pathology, Children s Hospital Boston and Harvard Medical School, Boston, MA, USA
    JAMA 296:2124-32. 2006
    ..Previously, abnormalities in 5-HT receptor binding in the medullae of infants dying from sudden infant death syndrome (SIDS) were identified, suggesting that medullary 5-HT dysfunction may be responsible for a subset of SIDS cases...
  40. ncbi request reprint Pediatric forensic pathology in crisis
    Roger W Byard
    Pediatr Dev Pathol 7:212-3. 2004
  41. ncbi request reprint Infants and toddlers must not be thought of as "miniature adults" - a forensic perspective
    Henry F Krous
    J Forensic Leg Med 14:451-2. 2007
  42. ncbi request reprint Pulmonary neuroendocrine cells and neuroepithelial bodies in sudden infant death syndrome: potential markers of airway chemoreceptor dysfunction
    Ernest Cutz
    Division of Pathology, Department of Paediatric Laboratory Medicine, The Hospital for Sick Children, Toronto, ON, M5G1X8, Canada
    Pediatr Dev Pathol 10:106-16. 2007
    ..Morphometric assessment and/or measurement of the secretory products of these cells (for example, CGA, bombesin) could provide a potential biological marker for SIDS...
  43. ncbi request reprint Sudden infant death syndrome: overview and update
    Roger W Byard
    Division of Pathology, Forensic Science Centre, 21 Divett Place, Adelaide 5000, South Australia, Australia
    Pediatr Dev Pathol 6:112-27. 2003
    ....
  44. ncbi request reprint Vascular endothelial growth factor in the cerebrospinal fluid of infants who died of sudden infant death syndrome: evidence for antecedent hypoxia
    Kimberly L Jones
    Kosair Children s Hospital Research Institute, Department of Pediatrics, University of Louisville School of Medicine, Louisville, Kentucky 40202, USA
    Pediatrics 111:358-63. 2003
    ..The vascular endothelial growth factor (VEGF) gene is highly sensitive to changes in tissue partial oxygen tension, and changes in genomic and protein expression occur even after changes in oxygenation within the physiologic range...
  45. ncbi request reprint Reflections on redefining SIDS
    Henry F Krous
    Arch Pediatr Adolesc Med 157:291-2. 2003
  46. ncbi request reprint Newborn hearing screens and SIDS
    Henry F Krous
    Early Hum Dev 84:371. 2008
  47. ncbi request reprint Serum testosterone and estradiol in sudden infant death
    Michael J Emery
    Department of Physiology and Biophysics, University of Miami School of Medicine, Miami, FL, USA
    J Pediatr 147:586-91. 2005
    ..To test the hypothesis that among infants who die unexpectedly, testosterone and/or estradiol levels are elevated in those diagnosed with SIDS versus those with known causes of death (controls)...
  48. ncbi request reprint Sudden infant death syndrome (SIDS)--standardised investigations and classification: recommendations
    Thomas Bajanowski
    Institute of Legal Medicine, University Duisburg Essen, Hufelandstr 55, 45122 Essen, Germany
    Forensic Sci Int 165:129-43. 2007
    ..Standardisation of infant death investigations with the application of uniform definitions and protocols will ensure optimal investigation of individual cases and enable international comparisons of trends...
  49. ncbi request reprint Why is a postmortem examination important when an infant or child dies suddenly?
    Henry F Krous
    Pediatr Dev Pathol 9:168-9. 2006
  50. ncbi request reprint Congenital mid ureteral strictures
    Andrew H Hwang
    Division of Urology, Childrens Hospital Los Angeles, Los Angeles, California 90027, USA
    J Urol 174:1999-2002. 2005
    ..Congenital mid ureteral stricture is rare. We report 7 cases, and discuss the differences in preoperative evaluation and surgical management compared to other obstructive entities...
  51. ncbi request reprint Pneumocystis is not a direct cause of sudden infant death syndrome
    Sergio L Vargas
    Programa de Microbiología Instituto de Ciencias Biomédicas, Facultad de Medicina Universidad de Chile, Santiago, Chile
    Pediatr Infect Dis J 26:81-3. 2007
    ..Cysts were identified in 33% of SIDS cases and 29% of controls. We conclude that Pneumocystis is not a direct cause of SIDS...