- Genetic variation in the TNFA promoter region and TNFA gene expression in subjects with asthmaBridgette L Jones
Children s Mercy Hospital, Kansas City, MO, USA
J Asthma 50:541-7. 2013..The purpose of this study was to determine how genetic variants within the promoter region of the TNFA gene differ between subjects with asthma and controls. We also investigated how genetic variation affects gene expression...
- Variability of histamine pharmacodynamic response in children with allergic rhinitisBridgette L Jones
Department of Paediatrics, University of Missouri, Kansas City, MO 64108, USA
J Clin Pharmacol 53:731-7. 2013..86) than the entire cohort (r(2) = 0.64). These data demonstrate a hyper-responsive histamine phenotype via HILD. This finding is important to future pharmacologic studies of antihistamines. ..
- Histamine: new thoughts about a familiar mediatorB L Jones
Department of Pediatrics, University of Missouri, Kansas City, Missouri, USA
Clin Pharmacol Ther 89:189-97. 2011..see Supplementary Data for full reference)...
- The impact of pharmacogenetics in the treatment of allergic disease and asthmaBridgette L Jones
Department of Pediatrics, Children s Mercy Hospital and Clinics, USA
Mo Med 108:361-5. 2011..This paper will discuss areas in allergic/inflammatory disease that have been impacted by pharmacogenetic research and how this application may be brought from the "bench to the bedside."..