Research Topics
| Amanda L JonesSummaryAffiliation: Children's Hospital and Regional Medical Center Country: USA Publications
| Collaborators
|
Detail Information
Publications
Penicillin-binding proteins in Streptococcus agalactiae: a novel mechanism for evasion of immune clearanceAmanda L Jones
Department of Pediatrics, Division of Infectious Diseases, Children s Hospital and Regional Medical Center and University of Washington, Seattle, WA 98105, USA
Mol Microbiol 47:247-56. 2003....
Abundance of the delta subunit of RNA polymerase is linked to the virulence of Streptococcus agalactiaeRavin Seepersaud
Department of Pediatrics, Division of Infectious Disease, Children's Hospital and University of Washington, Seattle, Washington 98109, USA
J Bacteriol 188:2096-105. 2006..These data suggest that a minimum intracellular concentration of delta is necessary for this organism to cause disease...
A streptococcal penicillin-binding protein is critical for resisting innate airway defenses in the neonatal lungAmanda L Jones
Division of Infectious Disease, Children s Hospital and Regional Medical Center, and Department of Pediatrics, University of Washington, 307 Westlake Avenue N, Seattle, WA 98109, USA
J Immunol 179:3196-202. 2007..Additionally, AM are traditionally thought to clear bacteria through phagocytic uptake; our data indicate that secretion of AMPs may also participate in limiting bacterial replication in the airway...
Construction and characterization of transposon TnphoZ for the identification of genes encoding exported proteins in Streptococcus agalactiaeAnne Clancy
Department of Pediatrics, Division of Infectious Disease, Children s Hospital and Regional Medical Center, University of Washington, Seattle, WA 98105, USA
FEMS Microbiol Lett 241:257-64. 2004..Sequence data correlated the expression of high AP activity with transposon insertion into genes encoding predicted exported proteins. It is anticipated that TnphoZ will be suitable for use in other Gram-positive hosts...
Penicillin-binding protein 1a promotes resistance of group B streptococcus to antimicrobial peptidesAndrea Hamilton
Department of Pediatrics, University of Washington, and Children s Hospital and Regional Medical Center, 307 Westlake Ave N, Suite 300, Seattle, WA 98109, USA
Infect Immun 74:6179-87. 2006..While the peptidoglycan polymerization and cross-linking activity of PBPs are essential for bacterial survival, our study is the first to identify a role for a PBP in resistance to host AMPs...
The Delta subunit of RNA polymerase is required for virulence of Streptococcus agalactiaeAmanda L Jones
Department of Pediatrics, Division of Infectious Diseases, Children s Hospital and Regional Medical Center and University of Washington, Seattle, Washington 98105, USA
Infect Immun 71:4011-7. 2003..Our data represent the first report of a phenotype relevant to virulence for rpoE mutants...
Staphylococcus aureus exploits cathelicidin antimicrobial peptides produced during early pneumonia to promote staphylokinase-dependent fibrinolysisMarissa H Braff
Division of Infectious Disease, Children s Hospital and Regional Medical Center, University of Washington, Seattle, WA 98109, USA
J Infect Dis 195:1365-72. 2007..These data suggest that staphylokinase production may be a novel virulence mechanism by which S. aureus exploits cathelicidin to promote fibrinolysis, leading to enhanced bacterial dissemination and invasive infection...
Role of Toll-like receptor 2 in innate resistance to Group B StreptococcusIain R Asplin
Division of Critical Care Medicine, Department of Pediatrics, Children s Hospital and Regional Medical Center, University of Washington, Seattle, WA 98105, USA
Microb Pathog 44:43-51. 2008..These data indicate that TLR2 is required for host defense against GBS and this response is unaffected by the absence of PBP1a and the resultant changes in cell wall ultrastructure...
Gordonia soli sp. nov., a novel actinomycete isolated from soilFo-Ting Shen
College of Agriculture and Natural Resources, Department of Soil and Environmental Sciences, National Chung Hsing University, Taichung, 402, Taiwan, Republic of China
Int J Syst Evol Microbiol 56:2597-601. 2006..nov. is proposed. The type strain is CC-AB07T (=BCRC 16810T=DSM 44995T)...
Rhodococcus gordoniae sp. nov., an actinomycete isolated from clinical material and phenol-contaminated soilAmanda L Jones
School of Biology, University of Newcastle, Newcastle upon Tyne NE1 7RU, UK
Int J Syst Evol Microbiol 54:407-11. 2004..The genotypic and phenotypic data show that the strains merit recognition as a novel species of Rhodococcus. The name proposed is Rhodococcus gordoniae sp. nov., with the type strain W 4937(T) (=DSM 44689(T)=NCTC 13296(T))...
Genome analysis of multiple pathogenic isolates of Streptococcus agalactiae: implications for the microbial "pan-genome"Herve Tettelin
Institute for Genomic Research, 9712 Medical Center Drive, Rockville, MD 20850, USA
Proc Natl Acad Sci U S A 102:13950-5. 2005..Mathematical extrapolation of the data suggests that the gene reservoir available for inclusion in the S. agalactiae pan-genome is vast and that unique genes will continue to be identified even after sequencing hundreds of genomes...
Rhodococcus aetherivorans sp. nov., a new species that contains methyl t-butyl ether-degrading actinomycetesMichael Goodfellow
School of Biology, University of Newcastle, Newcastle upon Tyne, UK
Syst Appl Microbiol 27:61-5. 2004..The genotypic and phenotypic data show that strains Bc663 and 10bc312T merit recognition as a new species of Rhodococcus. The name proposed for the new species is Rhodococcus aetherivorans (10bc312T = DSM 44752T = NCIMB 13964T)...
Dietzia papillomatosis sp. nov., a novel actinomycete isolated from the skin of an immunocompetent patient with confluent and reticulated papillomatosisAmanda L Jones
School of Biology, King George VIth Building, University of Newcastle, Newcastle upon Tyne NE1 7RU, UK
Int J Syst Evol Microbiol 58:68-72. 2008..It is apparent from genotypic and phenotypic data that the organism represents a novel species in the genus Dietzia. The name proposed for this taxon is Dietzia papillomatosis; the type strain is N 1280(T) (=DSM 44961(T)=NCIMB 14145(T))...
