A A Grom

Summary

Affiliation: Children's Hospital Medical Center
Country: USA

Publications

  1. ncbi Macrophage activation syndrome and reactive hemophagocytic lymphohistiocytosis: the same entities?
    Alexei A Grom
    Cincinnati Children s Hospital Medical Center, OH 45215, USA
    Curr Opin Rheumatol 15:587-90. 2003
  2. ncbi T-cell and T-cell receptor abnormalities in the immunopathogenesis of juvenile rheumatoid arthritis
    A A Grom
    William S Rowe Division of Rheumatology, Children s Hospital Medical Center, Cincinnati, Ohio 45229, USA
    Curr Opin Rheumatol 12:420-4. 2000
  3. ncbi Natural killer cell dysfunction in patients with systemic-onset juvenile rheumatoid arthritis and macrophage activation syndrome
    Alexei A Grom
    William S Rowe Division of Rheumatology, and the Division of Hematology Oncology, Children s Hospital Medical Center, Cincinnati, Ohio 45229, USA
    J Pediatr 142:292-6. 2003
  4. ncbi Expression of angiogenic factors in juvenile rheumatoid arthritis: correlation with revascularization of human synovium engrafted into SCID mice
    M P Scola
    Children's Hospital Medical Center, Cincinnati, Ohio 45229, USA
    Arthritis Rheum 44:794-801. 2001
  5. ncbi Antibodies to the 45 kDa DEK nuclear antigen in pauciarticular onset juvenile rheumatoid arthritis and iridocyclitis: selective association with MHC gene
    K J Murray
    Department of Pediatrics, Children s Hospital Medical Center, University of Cincinnati College of Medicine, OH 45229, USA
    J Rheumatol 24:560-7. 1997
  6. ncbi Systemic features and early prognostic factors in Hispanic and non-Hispanic children from the United States of America and Mexico with systemic juvenile idiopathic arthritis
    M Shishov
    Cincinnati Children s Hospital Medical Center, University of Cincinnati College of Medicine, Cincinnati, Ohio, USA
    Clin Exp Rheumatol 25:907-14. 2007
  7. ncbi Natural killer cell dysfunction: A common pathway in systemic-onset juvenile rheumatoid arthritis, macrophage activation syndrome, and hemophagocytic lymphohistiocytosis?
    Alexei A Grom
    Division of Rheumatology, Cincinnati Children s Hospital Medical Center, Cincinnati, Ohio 45215, USA
    Arthritis Rheum 50:689-98. 2004
  8. ncbi Natural killer cell dysfunction is a distinguishing feature of systemic onset juvenile rheumatoid arthritis and macrophage activation syndrome
    Joyce Villanueva
    1Division of Hematology/Oncology, Children's Hospital Medical Center, Cincinnati, Ohio, USA
    Arthritis Res Ther 7:R30-7. 2005
  9. ncbi The diagnostic significance of soluble CD163 and soluble interleukin-2 receptor alpha-chain in macrophage activation syndrome and untreated new-onset systemic juvenile idiopathic arthritis
    Jack Bleesing
    Children s Hospital Medical Center, Cincinnati, Ohio 45229, USA
    Arthritis Rheum 56:965-71. 2007
  10. ncbi Interleukin-15 inhibits sodium nitroprusside-induced apoptosis of synovial fibroblasts and vascular endothelial cells
    Lin Yang
    Children's Hospital Medical Center, Cincinnati, Ohio 45229, USA
    Arthritis Rheum 46:3010-4. 2002

Collaborators

  • Hermine Brunner
  • Daniel J Lovell
  • T Brent Graham
  • Murray H Passo
  • Joyce Villanueva
  • M Shishov
  • Norman T Ilowite
  • David D Sherry
  • Thomas Griffin
  • Jack Bleesing
  • Judyann Olson
  • Ndate Fall
  • Alexandra Filipovich
  • Sherry Thornton
  • David N Glass
  • Andrea C Barron
  • Michael P Scola
  • Lin Yang
  • M P Scola
  • E H Giannini
  • D N Glass
  • Susan Thompson
  • Robert A Colbert
  • Lorie Luyrink
  • R Burgos-Vargas
  • M Henrickson
  • R Romero-Feregrino
  • Anne Prada
  • Beth S Gottlieb
  • V Baca
  • Michael Barnes
  • Athimalaipet V Ramanan
  • N Rubio-Pérez
  • B Huang
  • David M Siegel
  • E Solis-Vallejo
  • Edward H Giannini
  • Susan Lee
  • Janalee Taylor
  • Thomas A Griffin
  • Terry Moore
  • Tsz-Leung Lee
  • K J Murray
  • Susan D Thompson
  • Monica K Tsoras
  • Marc A van Dijk
  • David Witte
  • T Imagawa
  • G P Boivin
  • R Hirsch
  • I S Szer
  • W Szer
  • P Donnelly
  • J E Levinson

Detail Information

Publications13

  1. ncbi Macrophage activation syndrome and reactive hemophagocytic lymphohistiocytosis: the same entities?
    Alexei A Grom
    Cincinnati Children s Hospital Medical Center, OH 45215, USA
    Curr Opin Rheumatol 15:587-90. 2003
    ....
  2. ncbi T-cell and T-cell receptor abnormalities in the immunopathogenesis of juvenile rheumatoid arthritis
    A A Grom
    William S Rowe Division of Rheumatology, Children s Hospital Medical Center, Cincinnati, Ohio 45229, USA
    Curr Opin Rheumatol 12:420-4. 2000
    ....
  3. ncbi Natural killer cell dysfunction in patients with systemic-onset juvenile rheumatoid arthritis and macrophage activation syndrome
    Alexei A Grom
    William S Rowe Division of Rheumatology, and the Division of Hematology Oncology, Children s Hospital Medical Center, Cincinnati, Ohio 45229, USA
    J Pediatr 142:292-6. 2003
    ..To assess natural killer (NK) and cytotoxic functions in patients with systemic-onset juvenile rheumatoid arthrithis (soJRA) complicated by macrophage activation syndrome (MAS)...
  4. ncbi Expression of angiogenic factors in juvenile rheumatoid arthritis: correlation with revascularization of human synovium engrafted into SCID mice
    M P Scola
    Children's Hospital Medical Center, Cincinnati, Ohio 45229, USA
    Arthritis Rheum 44:794-801. 2001
    ..CONCLUSION: JRA synovium is characterized by high angiogenic activity. SCID mouse-human JRA synovium chimeras may provide a good approach to study the in vivo regulation of angiogenesis in JRA...
  5. ncbi Antibodies to the 45 kDa DEK nuclear antigen in pauciarticular onset juvenile rheumatoid arthritis and iridocyclitis: selective association with MHC gene
    K J Murray
    Department of Pediatrics, Children s Hospital Medical Center, University of Cincinnati College of Medicine, OH 45229, USA
    J Rheumatol 24:560-7. 1997
    ..Class I and Class II HLA associations with reactivity to the antigen were also sought...
  6. ncbi Systemic features and early prognostic factors in Hispanic and non-Hispanic children from the United States of America and Mexico with systemic juvenile idiopathic arthritis
    M Shishov
    Cincinnati Children s Hospital Medical Center, University of Cincinnati College of Medicine, Cincinnati, Ohio, USA
    Clin Exp Rheumatol 25:907-14. 2007
    ....
  7. ncbi Natural killer cell dysfunction: A common pathway in systemic-onset juvenile rheumatoid arthritis, macrophage activation syndrome, and hemophagocytic lymphohistiocytosis?
    Alexei A Grom
    Division of Rheumatology, Cincinnati Children s Hospital Medical Center, Cincinnati, Ohio 45215, USA
    Arthritis Rheum 50:689-98. 2004
  8. ncbi Natural killer cell dysfunction is a distinguishing feature of systemic onset juvenile rheumatoid arthritis and macrophage activation syndrome
    Joyce Villanueva
    1Division of Hematology/Oncology, Children's Hospital Medical Center, Cincinnati, Ohio, USA
    Arthritis Res Ther 7:R30-7. 2005
    ..This phenomenon was particularly common in the systemic form of JRA, a clinical entity strongly associated with MAS...
  9. ncbi The diagnostic significance of soluble CD163 and soluble interleukin-2 receptor alpha-chain in macrophage activation syndrome and untreated new-onset systemic juvenile idiopathic arthritis
    Jack Bleesing
    Children s Hospital Medical Center, Cincinnati, Ohio 45229, USA
    Arthritis Rheum 56:965-71. 2007
    ..This study was undertaken to assess the value of serum sIL-2Ralpha and sCD163 in diagnosing acute macrophage activation syndrome complicating systemic juvenile idiopathic arthritis (JIA)...
  10. ncbi Interleukin-15 inhibits sodium nitroprusside-induced apoptosis of synovial fibroblasts and vascular endothelial cells
    Lin Yang
    Children's Hospital Medical Center, Cincinnati, Ohio 45229, USA
    Arthritis Rheum 46:3010-4. 2002
    ..CONCLUSION: IL-15 promotes survival of VECs on Matrigel and inhibits SNP-induced apoptosis of endothelial cells. We hypothesize that this mechanism may be relevant to the stabilization of newly formed vascular structures in JRA synovium...
  11. ncbi Interferon-gamma:interleukin 4 ratios and associated type 1 cytokine expression in juvenile rheumatoid arthritis synovial tissue
    Michael P Scola
    Department of Pediatrics, Children's Hospital Medical Center, Cincinnati, Ohio 45229-3039, USA
    J Rheumatol 29:369-78. 2002
    ..The strong correlation between IFN-gamma and IL-12 in JRA suggests a prominent role for IL-12 in promoting the type I bias, while IL-15 and IL-18 may also indirectly increase IFN-gamma expression and further bias the immune response...
  12. ncbi Feasibility and construct validity of the parent willingness-to-pay technique for children with juvenile idiopathic arthritis
    Andrea C Barron
    Cincinnati Children's Hospital Medical Center, University of Cincinnati, Cincinnati, Ohio 45229-3039, USA
    Arthritis Rheum 51:899-908. 2004
    ..Relatively large WTP estimates support a possible important negative impact of the disease on families of children with JIA...
  13. ncbi Gene expression profiling of peripheral blood from patients with untreated new-onset systemic juvenile idiopathic arthritis reveals molecular heterogeneity that may predict macrophage activation syndrome
    Ndate Fall
    Children s Hospital Medical Center, Cincinnati, Ohio 45229, USA
    Arthritis Rheum 56:3793-804. 2007
    ..This study was undertaken to better understand the relationship between systemic JIA and macrophage activation syndrome...