Research Topics
Genomes and Genes | John H GreinwaldSummaryAffiliation: Children's Hospital Medical Center Country: USA Publications
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Detail Information
Publications
Clinical and audiological features in auditory neuropathyColm Madden
Center for Hearing and Deafness Research, Department of Pediatric Otolaryngology, Children s Hospital Medical Center, 3333 Burnet Ave, Cincinnati, OH 45229, USA
Arch Otolaryngol Head Neck Surg 128:1026-30. 2002..To medically and audiologically characterize a population of children diagnosed as having auditory neuropathy (AN)...
Improved diagnostic effectiveness with a sequential diagnostic paradigm in idiopathic pediatric sensorineural hearing lossDiego A Preciado
Center for Hearing and Deafness Research (CHDR) and the Division of Pediatric Otolaryngology, Cincinnati, Ohio 45229-3039, USA
Otol Neurotol 26:610-5. 2005..Laboratory investigation should not be routine but based on clinical history...
A diagnostic paradigm for childhood idiopathic sensorineural hearing lossDiego A Preciado
Center for Hearing and Deafness Research, Division of Pediatric Otolaryngology Head and Neck Surgery, Cincinnati Children s Hospital Medical Center, Ohio 45229 3039, USA
Otolaryngol Head Neck Surg 131:804-9. 2004..Our objective was to determine the diagnostic yield of laboratory testing, radiological imaging, and GJB2 mutation screening in a large cohort of patients with differing severities of idiopathic sensorineural hearing loss (SNHL)...
High-throughput detection of mutations responsible for childhood hearing loss using resequencing microarraysPrachi Kothiyal
1Biomedical Informatics, Cincinnati Children s Hospital Medical Center, Cincinnati, Ohio 45229, USA
BMC Biotechnol 10:10. 2010..We present results from hearing loss arrays developed in two different research facilities and highlight some of the approaches we adopted to enhance the applicability of resequencing arrays in a clinical setting...
Macrophage inflammatory proteins in cytomegalovirus-related inner ear injuryScott A Schraff
Department of Pediatric Otolaryngology Head and Neck Surgery, Cincinnati Children s Hospital Medical Center, Cincinnati, OH 45229 3039, USA
Otolaryngol Head Neck Surg 137:612-8. 2007..The purpose of the study was to determine if a virally encoded macrophage inflammatory protein played a role in CMV-related hearing loss...
Refining the DFNB17 interval in consanguineous Indian familiesYingshi Guo
Center for Hearing and Deafness Research, Department of Otolaryngology, Cincinnati, Children s Hospital Cincinnati, OH, USA
Mol Biol Rep 31:97-105. 2004..Analysis of coding and splice site regions of these cochlear expressed genes did not reveal any disease causing mutations. Further study of other candidate genes is currently underway...
The role of CMV inflammatory genes in hearing lossScott A Schraff
Department of Pediatric Otolaryngology Head and Neck Surgery, Cincinnati Children s Hospital Medical Center, Cincinnati, Ohio 45229 3039, USA
Otol Neurotol 28:964-9. 2007..The purpose of this study is to test the hypothesis that virally encoded immunomodulatory genes play a role in cytomegalovirus (CMV)-related hearing loss...
An overview of custom array sequencingPrachi Kothiyal
Cincinnati Children s Hospital Medical Center, Cincinnati, Ohio, USA
Curr Protoc Hum Genet . 2009..Critical topics in the design, implementation, and analysis of targeted sequencing arrays not previously discussed in detail are highlighted...
Neuroanatomic differences in children with unilateral sensorineural hearing loss detected using functional magnetic resonance imagingEvan J Propst
Division of Pediatric Otolaryngology Head and Neck Surgery, Cincinnati Children s Hospital Medical Center, MLC 2018, 3333 Burnet Ave, Cincinnati, OH 45229 3039, USA
Arch Otolaryngol Head Neck Surg 136:22-6. 2010..This study used fMRI to compare neuroanatomic activation patterns in children with unilateral sensorineural hearing loss (USNHL) with the neuroanatomic activation patterns in normally hearing individuals...
The cochlear cleftJon B Chadwell
Department of Otolaryngology, Cincinnati Children's Hospital Medical Center and the University of Cincinnati College of Medicine, Cincinnati, OH, USA
AJNR Am J Neuroradiol 25:21-4. 2004..Incidence decreased with age. CONCLUSION: We describe a cleft in the otic capsule that is frequently seen on magnified images of temporal bone CT studies in children. The cleft may be the fissula ante fenestram...
Genotypic and phenotypic correlations of DFNB1-related hearing impairment in the Midwestern United StatesLynne H Y Lim
Center for Hearing and Deafness Research, Cincinnati, Ohio, USA
Arch Otolaryngol Head Neck Surg 129:836-40. 2003..To determine the genotypic and phenotypic correlations of hearing impairment (HI) in a midwestern US population related to autosomal recessive nonsyndromic hearing loss locus 1 (DFNB1)...
Co-expression of pendrin, vacuolar H+-ATPase alpha4-subunit and carbonic anhydrase II in epithelial cells of the murine endolymphatic sacHongwei Dou
Center for Hearing and Deafness Research, Department of Pediatric Otolaryngology, Cincinnati Children s Hospital Medical Center, 3333 Burnet Avenue, Cincinnati, OH 45229 3039, USA
J Histochem Cytochem 52:1377-84. 2004....
Genomic organization and expression analysis of the murine Fam3c geneValentina V Pilipenko
Center for Hearing and Deafness Research, Division of Otolaryngology, Cincinnati Children s Hospital Medical Center, 3333 Burnet Avenue, Cincinnati, OH 45229, USA
Gene 335:159-68. 2004..Further study is underway to determine the role of FAM3C in inner ear development...
H1N1 influenza A presenting as bacterial tracheitisBrandon S Hopkins
Department of Otolaryngology Head and Neck Surgery, Cincinnati Children s Hospital Medical Center, University of Cincinnati College of Medicine, Cincinnati, OH 45267 0528, USA
Otolaryngol Head Neck Surg 142:612-4. 2010..In hospitalized patients with presumed BT, consideration should be given to routine H1N1 testing and the addition of antiviral medication when indicated as this entity is further investigated...
Temporal bone abnormalities associated with hearing loss in Waardenburg syndromeColm Madden
Center of Hearing and Deafness Research, Cincinnati Children's Hospital Medical Center, Ohio 45229, USA
Laryngoscope 113:2035-41. 2003..As shown by computed tomography, enlargement of the vestibular aqueduct and the upper vestibule, narrowing of the internal auditory canal porus, and hypoplasia of the modiolus are features of Waardenburg syndrome...
