Vittorio Gallo

Summary

Affiliation: Children's National Medical Center
Country: USA

Publications

  1. ncbi request reprint Identification of Sox17 as a transcription factor that regulates oligodendrocyte development
    Jiho Sohn
    Center for Neuroscience Research, Children s National Medical Center, Washington, DC 20010, USA
    J Neurosci 26:9722-35. 2006
  2. pmc Synapses on NG2-expressing progenitors in the brain: multiple functions?
    Vittorio Gallo
    Center for Neuroscience Research, Children s National Medical Center, 111 Michigan Ave NW, Washington, DC 20010, USA
    J Physiol 586:3767-81. 2008
  3. pmc Myelin repair strategies: a cellular view
    Vittorio Gallo
    Center for Neuroscience Research, Children s National Medical Center, Washington, District of Columbia 20010, USA
    Curr Opin Neurol 21:278-83. 2008
  4. pmc GABA: exciting again in its own right
    Vittorio Gallo
    Center for Neuroscience Research, Children s Research Institute, Children s National Medical Center, 111 Michigan Avenue, N W, Washington, DC 20010 2970, USA
    J Physiol 550:665. 2003
  5. ncbi request reprint Preface: white matter disorders
    Vittorio Gallo
    Center for Neuroscience Research and MRDDRC, Children s National Medical Center, Washington, District of Columbia 200100 2970, USA
    Ment Retard Dev Disabil Res Rev 12:83-4. 2006
  6. doi request reprint Chordin-induced lineage plasticity of adult SVZ neuroblasts after demyelination
    Beata Jablonska
    Center for Neuroscience Research, Children s National Medical Center, Washington, DC, USA
    Nat Neurosci 13:541-50. 2010
  7. pmc Pax6 is required at the telencephalic pallial-subpallial boundary for the generation of neuronal diversity in the postnatal limbic system
    Laura A Cocas
    Center for Neuroscience Research, Children s Research Institute, Children s National Medical Center, Washington, DC 20010, USA
    J Neurosci 31:5313-24. 2011
  8. pmc NG2-expressing cells in the subventricular zone are type C-like cells and contribute to interneuron generation in the postnatal hippocampus
    Adan A Aguirre
    Center for Neuroscience Research, Children s Research Institute, Rm 5345, Children s National Medical Center, 111 Michigan Ave, N W, Washington, DC 20010, USA
    J Cell Biol 165:575-89. 2004
  9. doi request reprint Adult-born SVZ progenitors receive transient synapses during remyelination in corpus callosum
    Ainhoa Etxeberria
    Center for Neuroscience Research, Children s National Medical Center, Washington, DC, USA
    Nat Neurosci 13:287-9. 2010
  10. pmc Satellite NG2 progenitor cells share common glutamatergic inputs with associated interneurons in the mouse dentate gyrus
    Jean Marie Mangin
    Department of Neurology, Center for Neuroscience Research, Children s National Medical Center, Washington, DC 20010, USA
    J Neurosci 28:7610-23. 2008

Collaborators

Detail Information

Publications57

  1. ncbi request reprint Identification of Sox17 as a transcription factor that regulates oligodendrocyte development
    Jiho Sohn
    Center for Neuroscience Research, Children s National Medical Center, Washington, DC 20010, USA
    J Neurosci 26:9722-35. 2006
    ..These findings support important roles for Sox17 in controlling both oligodendrocyte progenitor cell cycle exit and differentiation...
  2. pmc Synapses on NG2-expressing progenitors in the brain: multiple functions?
    Vittorio Gallo
    Center for Neuroscience Research, Children s National Medical Center, 111 Michigan Ave NW, Washington, DC 20010, USA
    J Physiol 586:3767-81. 2008
    ....
  3. pmc Myelin repair strategies: a cellular view
    Vittorio Gallo
    Center for Neuroscience Research, Children s National Medical Center, Washington, District of Columbia 20010, USA
    Curr Opin Neurol 21:278-83. 2008
    ..This brief review highlights recent cellular and molecular findings and indicates that future therapeutic strategies to enhance remyelination may also require combinatorial treatment to accomplish...
  4. pmc GABA: exciting again in its own right
    Vittorio Gallo
    Center for Neuroscience Research, Children s Research Institute, Children s National Medical Center, 111 Michigan Avenue, N W, Washington, DC 20010 2970, USA
    J Physiol 550:665. 2003
  5. ncbi request reprint Preface: white matter disorders
    Vittorio Gallo
    Center for Neuroscience Research and MRDDRC, Children s National Medical Center, Washington, District of Columbia 200100 2970, USA
    Ment Retard Dev Disabil Res Rev 12:83-4. 2006
  6. doi request reprint Chordin-induced lineage plasticity of adult SVZ neuroblasts after demyelination
    Beata Jablonska
    Center for Neuroscience Research, Children s National Medical Center, Washington, DC, USA
    Nat Neurosci 13:541-50. 2010
    ..Our findings suggest that the lineage plasticity of SVZ progenitor cells could be a potential therapeutic strategy for diseased or injured brain...
  7. pmc Pax6 is required at the telencephalic pallial-subpallial boundary for the generation of neuronal diversity in the postnatal limbic system
    Laura A Cocas
    Center for Neuroscience Research, Children s Research Institute, Children s National Medical Center, Washington, DC 20010, USA
    J Neurosci 31:5313-24. 2011
    ..Thus, in PSB progenitors, Pax6 plays an important role in the generation of multiple subtypes of neurons that contribute to the amygdala and olfactory bulb...
  8. pmc NG2-expressing cells in the subventricular zone are type C-like cells and contribute to interneuron generation in the postnatal hippocampus
    Adan A Aguirre
    Center for Neuroscience Research, Children s Research Institute, Rm 5345, Children s National Medical Center, 111 Michigan Ave, N W, Washington, DC 20010, USA
    J Cell Biol 165:575-89. 2004
    ....
  9. doi request reprint Adult-born SVZ progenitors receive transient synapses during remyelination in corpus callosum
    Ainhoa Etxeberria
    Center for Neuroscience Research, Children s National Medical Center, Washington, DC, USA
    Nat Neurosci 13:287-9. 2010
    ..Therefore, axon-oligodendrocyte progenitor synapse formation is a transient and regulated step that occurs during remyelination of callosal axons...
  10. pmc Satellite NG2 progenitor cells share common glutamatergic inputs with associated interneurons in the mouse dentate gyrus
    Jean Marie Mangin
    Department of Neurology, Center for Neuroscience Research, Children s National Medical Center, Washington, DC 20010, USA
    J Neurosci 28:7610-23. 2008
    ..The finding that NG2(+) cells are sensing patterns of activity arising in closely associated neurons suggests that NG2(+) cell function is finely regulated by the local network...
  11. pmc Modulation of the Wnt/beta-catenin pathway in human oligodendroglioma cells by Sox17 regulates proliferation and differentiation
    Hui Ling Chen
    Center for Neuroscience Research, Children s National Medical Center, Washington, DC 20010, USA
    Cancer Lett 335:361-71. 2013
    ..Our results thus identify Sox17 as a potential molecular target to include in HOG therapeutic strategies...
  12. ncbi request reprint A functional role for EGFR signaling in myelination and remyelination
    Adan Aguirre
    Center for Neuroscience Research, Children s National Medical Center, 111 Michigan Ave, NW, Washington, DC 20010 2970, USA
    Nat Neurosci 10:990-1002. 2007
    ..EGFR targeting holds promise for enhancing oligodendrocyte regeneration and myelin repair...
  13. pmc Chronic perinatal hypoxia reduces glutamate-aspartate transporter function in astrocytes through the Janus kinase/signal transducer and activator of transcription pathway
    Matthew Raymond
    Center for Neuroscience Research, Children s National Medical Center, Washington, DC 20010, USA
    J Neurosci 31:17864-71. 2011
    ....
  14. ncbi request reprint Postnatal neurogenesis and gliogenesis in the olfactory bulb from NG2-expressing progenitors of the subventricular zone
    Adan Aguirre
    Center for Neuroscience Research, Children s Research Institute, Children s National Medical Center, Washington, DC 20010, USA
    J Neurosci 24:10530-41. 2004
    ..Our findings indicate region-specific differences between NG2+ progenitor cells and show that NG2+ cells can migrate throughout the RMS and contribute to both gliogenesis and neurogenesis in the postnatal OB...
  15. ncbi request reprint Overexpression of the epidermal growth factor receptor confers migratory properties to nonmigratory postnatal neural progenitors
    Adan Aguirre
    Center for Neuroscience Research, Children s Research Institute, Children s National Medical Center, Washington, DC 20010, USA
    J Neurosci 25:11092-106. 2005
    ..These findings reveal a new role for EGFR in the postnatal brain and open new avenues to optimize cell engraftment for brain repair...
  16. pmc Transgenic overexpression of Sox17 promotes oligodendrocyte development and attenuates demyelination
    Xiaotian Ming
    Center for Neuroscience Research, Children s Research Institute, Children s National Medical Center, Washington, DC 20010, USA
    J Neurosci 33:12528-42. 2013
    ..This study demonstrates that overexpression of this transcription factor might be a viable protective strategy to mitigate the consequences of demyelination in the adult WM. ..
  17. pmc Rodent brain slice model for the study of white matter injury
    Akira Murata
    Children s National Heart Institute, Children s National Medical Center, Washington, DC Center for Neuroscience Research, Children s National Medical Center, Washington, DC
    J Thorac Cardiovasc Surg 146:1526-1533.e1. 2013
    ..To understand better the mechanisms associated with WM injury, we tested the adequacy of a novel ex vivo brain slice model, with a particular focus on how the maturational stage modulates the injury...
  18. pmc NG2 cell response in the CNP-EGFP mouse after contusive spinal cord injury
    Judith M Lytle
    Department of Neuroscience, Georgetown University, Washington, District of Columbia, USA
    Glia 57:270-85. 2009
    ..The EGFP(+)NG2(+) cells undergo cellular and physiological changes in response to SCI that are similar to those that occur in early postnatal NG2(+) cells during developmental oligodendrogenesis...
  19. pmc Endothelin-1 regulates oligodendrocyte development
    Ana Gadea
    Center for Neuroscience Research, Children s Research Institute, Children s National Medical Center, Washington, DC 20010, USA
    J Neurosci 29:10047-62. 2009
    ..Our findings indicate that ET-1 is a soluble astrocyte-derived signal that regulates OPC migration and differentiation during development...
  20. ncbi request reprint Differential synaptic integration of interneurons in the outer and inner molecular layers of the developing dentate gyrus
    Ramesh Chittajallu
    Center for Neuroscience Research, Children s National Medical Center, Washington, DC 20010, USA
    J Neurosci 27:8219-25. 2007
    ..Our data provide evidence that developing ML interneurons receive functional glutamatergic and GABAergic inputs and undergo significant changes in synaptic integration during migration from the OML to the IML...
  21. pmc Neonatal hyperoxia exposure disrupts axon-oligodendrocyte integrity in the subcortical white matter
    Jonathan Ritter
    Center for Neuroscience Research, Children s National Medical Center, Washington, District of Columbia 20010, USA
    J Neurosci 33:8990-9002. 2013
    ..Understanding the pathology of premature PWMI injury will allow for the development of interventional strategies to preserve WM integrity and function...
  22. pmc Experience-dependent regulation of NG2 progenitors in the developing barrel cortex
    Jean Marie Mangin
    Center for Neuroscience Research, Children s National Medical Center, Washington, DC, USA
    Nat Neurosci 15:1192-4. 2012
    ..Thus, early sensory experience regulates thalamocortical innervation on NG2 cells, as well as their proliferation and distribution during development...
  23. pmc Long-term, selective gene expression in developing and adult hippocampal pyramidal neurons using focal in utero electroporation
    Ivan Navarro-Quiroga
    Center for Neuroscience Research, Children s National Medical Center, Washington, DC 20010, USA
    J Neurosci 27:5007-11. 2007
  24. pmc Notch and EGFR pathway interaction regulates neural stem cell number and self-renewal
    Adan Aguirre
    Center for Neuroscience Research, Children s National Medical Center, Washington, District of Columbia 20010, USA
    Nature 467:323-7. 2010
    ..Our findings define a novel interaction between EGFR and Notch pathways in the adult SVZ, and thus provide a mechanism for NSC and NPC pool maintenance...
  25. pmc Mechanisms of regulation of oligodendrocyte development by p38 mitogen-activated protein kinase
    Li Jin Chew
    Center for Neuroscience Research, Children s Research Institute, Children s National Medical Center, Washington, DC 20010, USA
    J Neurosci 30:11011-27. 2010
    ..We show that oligodendrocyte differentiation involves p38-mediated Sox10 regulation and cross talk with parallel ERK and JNK pathways to repress c-Jun activity...
  26. pmc The curious case of NG2 cells: transient trend or game changer?
    Jean Marie Mangin
    Center for Neuroscience Research, Childrens National Medical Center, Washington, DC 20010, USA
    ASN Neuro 3:e00052. 2011
    ....
  27. pmc Sonic hedgehog expressing and responding cells generate neuronal diversity in the medial amygdala
    Rosalind S E Carney
    Center for Neuroscience Research, Children s Research Institute, Children s National Medical Center, Washington, DC 20010, USA
    Neural Dev 5:14. 2010
    ..However, the development of the neuronal diversity of this complex and important structure remains to be fully elucidated...
  28. pmc Cdk2 is critical for proliferation and self-renewal of neural progenitor cells in the adult subventricular zone
    Beata Jablonska
    Center for Neuroscience Research, Children s National Medical Center, Washington, DC 20010, USA
    J Cell Biol 179:1231-45. 2007
    ..Thus, although Cdk2 is functionally redundant in perinatal SVZ, it is important for adult progenitor cell proliferation and self-renewal through age-dependent regulation of Cdk4...
  29. pmc Cellular changes underlying hyperoxia-induced delay of white matter development
    Thomas Schmitz
    Center for Neuroscience Research, Children s National Medical Center, Washington, DC 20010, USA
    J Neurosci 31:4327-44. 2011
    ..Understanding the cellular dynamics and underlying mechanisms involved in hyperoxia-induced PWMI will allow for future targeted therapeutic intervention...
  30. doi request reprint Gene expression profiling of astrocytes from hyperammonemic mice reveals altered pathways for water and potassium homeostasis in vivo
    Uta Lichter-Konecki
    Center for Neuroscience Research, Children s National Medical Center, Washington, DC 20010, USA
    Glia 56:365-77. 2008
    ..Our results suggest that alterations in astrocyte-mediated water and potassium homeostasis in brain may be key to the development of the brain edema...
  31. pmc Oligodendrocyte regeneration after neonatal hypoxia requires FoxO1-mediated p27Kip1 expression
    Beata Jablonska
    Children s National Medical Center, Washington, DC 20010 2970, USA
    J Neurosci 32:14775-93. 2012
    ..Thus, FoxO1 and p27(Kip1) may serve as promising target molecules for promoting timely oligodendrogenesis in neonatal DWMI...
  32. pmc Postnatal NG2 proteoglycan-expressing progenitor cells are intrinsically multipotent and generate functional neurons
    Shibeshih Belachew
    Center for Neuroscience Research, Children s Research Institute, Children s National Medical Center, Washington, DC 20010 2970, USA
    J Cell Biol 161:169-86. 2003
    ..These data show that at least a subpopulation of postnatal NG2-expressing cells are CNS multipotent precursors that may underlie adult hippocampal neurogenesis...
  33. pmc White matter protection in congenital heart surgery
    Nobuyuki Ishibashi
    Children s National Medical Center, 111 Michigan Ave NW, Washington, DC 20010 2970, USA
    Circulation 125:859-71. 2012
    ..Our aim is to identify an optimal surgical strategy for WM protection to reduce neurological injury in congenital heart disease patients...
  34. pmc SRY-box containing gene 17 regulates the Wnt/β-catenin signaling pathway in oligodendrocyte progenitor cells
    Li Jin Chew
    Center for Neuroscience Research, and Center for Genetic Medicine Research, Children s Research Institute, Children s National Medical Center, Washington, DC 20010, USA
    J Neurosci 31:13921-35. 2011
    ..Our identification of downstream targets of Sox17 thus defines signaling pathways and molecular mechanisms in OPCs that are regulated by Sox17 during cell cycle exit and the onset of differentiation in oligodendrocyte development...
  35. pmc The Yin and Yang of Sox proteins: Activation and repression in development and disease
    Li Jin Chew
    Center for Neuroscience Research, Children s National Medical Center, Washington, DC, USA
    J Neurosci Res 87:3277-87. 2009
    ..Here we seek to provide an overview of the current knowledge of Sox gene functional mechanisms, in an effort to understand their roles in both development and pathology...
  36. ncbi request reprint Downregulation of platelet-derived growth factor-alpha receptor-mediated tyrosine kinase activity as a cellular mechanism for K+-channel regulation during oligodendrocyte development in situ
    Ramesh Chittajallu
    Center for Neuroscience Research, Children s Research Institute, Children s National Medical Center, Washington, DC 20010, USA
    J Neurosci 25:8601-10. 2005
    ..Together, these data indicate that PDGFR-alpha and tyrosine kinase activity act via a common pathway that influences functional expression of K+ channels and proliferative capacity of OPs in situ...
  37. ncbi request reprint Interferon-gamma inhibits cell cycle exit in differentiating oligodendrocyte progenitor cells
    Li Jin Chew
    Center for Neuroscience Research, Children s Research Institute, Children s National Medical Center, Washington, DC 20010, USA
    Glia 52:127-43. 2005
    ....
  38. pmc Environmental enrichment rescues postnatal neurogenesis defect in the male and female Ts65Dn mouse model of Down syndrome
    Lina Chakrabarti
    Center for Neuroscience Research, Children s National Medical Center, Washington, DC, USA
    Dev Neurosci 33:428-41. 2011
    ....
  39. pmc Endothelin-1 regulates astrocyte proliferation and reactive gliosis via a JNK/c-Jun signaling pathway
    Ana Gadea
    Center for Neuroscience Research, Children s National Medical Center, Washington, DC 20010, USA
    J Neurosci 28:2394-408. 2008
    ....
  40. pmc Secretome Survey of Human Plexiform Neurofibroma Derived Schwann Cells Reveals a Secreted form of the RARRES1 Protein
    Hui Ling Chen
    Children s National Medical Center, 111 Michigan Avenue NW, Washington, DC 20010, USA E Mails H L C H S K J B H G D A H V G R P
    Int J Mol Sci 13:9380-99. 2012
    ..This study shows altered secretion of key proteins in NF1 derived Schwann cells. The potential implication of these proteins in neurofibroma biology is discussed...
  41. ncbi request reprint Metallothionein I and II mitigate age-dependent secondary brain injury
    Joanne E Natale
    Research Center for Genetic Medicine, Children s National Medical Center, 111 Michigan Ave, NW, Washington, DC 20010, USA
    J Neurosci Res 78:303-14. 2004
    ..These findings have implications for the development of age-specific therapeutic strategies to enhance recovery after brain injury...
  42. ncbi request reprint Brain development and the ontogeny of developmental disabilities
    Maria Acosta
    Children s National Medical Center, Washington, DC, USA
    Adv Pediatr 49:1-57. 2002
    ..As we learn more about the genetic mechanism and molecular processes underlying brain development, we will better understand the ontogeny of various developmental disabilities and hopefully improve approaches to prevention and treatment...
  43. doi request reprint E2F1 Coregulates Cell Cycle Genes and Chromatin Components during the Transition of Oligodendrocyte Progenitors from Proliferation to Differentiation
    Laura Magri
    Departments of Neuroscience, Genetics and Genomics, and Medicine, Icahn School of Medicine at Mount Sinai, New York, New York 10029, Center for Neuroscience Research, Children s National Medical Center, George Washington University, Washington, DC 20010 2970, and Department of Pathology and Cell Biology, Columbia University Medical Center, New York, New York 10032
    J Neurosci 34:1481-93. 2014
    ..Together, these data identify E2F1 as a key transcription factor modulating the expression of chromatin components in OPC during the transition from proliferation to differentiation. ..
  44. pmc Reduced EGFR signaling in progenitor cells of the adult subventricular zone attenuates oligodendrogenesis after demyelination
    Adan Aguirre
    Center for Neuroscience Research, Children s National Medical Center, 111 Michigan Avenue, NW Washington, DC 20010, USA
    Neuron Glia Biol 3:209-20. 2007
    ..Our results demonstrate that the response of NG2(+) cells in the SVZ and their subsequent differentiation in CC after focal demyelination depend on EGFR signaling...
  45. ncbi request reprint Determining the fetal inflammatory response in an experimental model of intrauterine inflammation in rats
    Michael J Bell
    Center for Neuroscience Research, Children s Research Institute, Children s National Medical Center, Washington University School of Medicine, Washington, D C, 20010 USA
    Pediatr Res 56:541-6. 2004
    ..By studying placental and brain cytokine responses in models such as ours, the mechanisms responsible for the damage to developing white matter can be determined...
  46. ncbi request reprint Inflammation in white matter: clinical and pathophysiological aspects
    David Pleasure
    Deparment of Neurology, UC Davis School of Medicine, and Shriners Hospitals for Children Northern California, Sacramento, California 95817, USA
    Ment Retard Dev Disabil Res Rev 12:141-6. 2006
    ....
  47. ncbi request reprint Astrogliosis in EAE spinal cord: derivation from radial glia, and relationships to oligodendroglia
    Peter Bannerman
    Institute for Pediatric Regenerative Research, UC Davis School of Medicine, Shriners Hospital for Children, Northern California, Sacramento, California 95817, USA
    Glia 55:57-64. 2007
    ....
  48. ncbi request reprint Cyclin-dependent kinase-2 controls oligodendrocyte progenitor cell cycle progression and is downregulated in adult oligodendrocyte progenitors
    Shibeshih Belachew
    Laboratory of Cellular and Synaptic Neurophysiology, National Institute of Child Health and Human Development, National Institutes of Health, Bethesda, Maryland 20892 4495, USA
    J Neurosci 22:8553-62. 2002
    ....
  49. ncbi request reprint Expression of the green fluorescent protein in the oligodendrocyte lineage: a transgenic mouse for developmental and physiological studies
    Xiaoqing Yuan
    Laboratory of Cellular and Synaptic Neurophysiology, National Institute of Child Health and Human Development, National Institutes of Health, Bethesda, Maryland, USA
    J Neurosci Res 70:529-45. 2002
    ..Oligodendrocyte development and physiology can be studied in live tissue of CNP-EGFP transgenic mice, which represent a source of pure EGFP(+) oligodendrocyte-lineage cells throughout development...
  50. pmc Adenosine: a neuron-glial transmitter promoting myelination in the CNS in response to action potentials
    Beth Stevens
    Laboratory of Cellular and Synaptic Neurophysiology, National Institutes of Health, NICHD, Bethesda, MD 20892, USA
    Neuron 36:855-68. 2002
    ....
  51. ncbi request reprint CDK2 is dispensable for adult hippocampal neurogenesis
    Renaud Vandenbosch
    Center for Cellular and Molecular Neuroscience, University of Liege, Liege, Belgium
    Cell Cycle 6:3065-9. 2007
    ..These data emphasize that functional redundancies between Cdks also occur in the adult brain at the level of neural progenitor cell cycle regulation during hippocampal neurogenesis...
  52. pmc Galactocerebrosidase-deficient oligodendrocytes maintain stable central myelin by exogenous replacement of the missing enzyme in mice
    Yoichi Kondo
    Department of Medical Sciences, School of Veterinary Medicine, University of Wisconsin, Madison, WI 53706, USA
    Proc Natl Acad Sci U S A 102:18670-5. 2005
    ..These findings suggest that the mutant OLs can internalize exogenous GALC and maintain stable myelin, demonstrating that exogenous enzyme replacement will be a key strategy in the therapy of GLD...
  53. ncbi request reprint The Yin and Yang of cell cycle progression and differentiation in the oligodendroglial lineage
    Laurent Nguyen
    Developmental Neurobiology Unit, Center for Cellular and Molecular Neuroscience, University of Liege, C H U Sart Tilman, B36, 4000 Liege, Belgium
    Ment Retard Dev Disabil Res Rev 12:85-96. 2006
    ..e. the initial steps of oligodendrocyte lineage progression that are obviously crucial in health and diseases...
  54. ncbi request reprint Shaker-type potassium channel subunits differentially control oligodendrocyte progenitor proliferation
    Francois Vautier
    Laboratory of Cellular and Synaptic Neurophysiology, National Institute of Child Health and Human Development, National Institutes of Health, Bethesda, Maryland, USA
    Glia 48:337-45. 2004
    ....
  55. ncbi request reprint Synaptic and extrasynaptic neurotransmitter receptors in glial precursors' quest for identity
    Shibeshih Belachew
    Center for Cellular and Molecular Neurobiology, University of Liege, Liege, Belgium
    Glia 48:185-96. 2004
    ..The present review integrates recent advances, to shed new light on how neurotransmitter receptors may, alternatively, serve as excitable mediators of neuron-glia and neuron-neuroblast interactions...
  56. ncbi request reprint Surprising synapses deep in the brain
    Vittorio Gallo
    Nat Neurosci 10:267-9. 2007
  57. ncbi request reprint Expression of a catalytically inactive transmembrane protein tyrosine phosphatase epsilon (tm-PTP epsilon) delays optic nerve myelination
    Naser Muja
    Section of Developmental Genetics, National Institute of Neurological Disorders and Stroke, National Institutes of Health, Bethesda, Maryland 20892 4160, USA
    Glia 48:278-97. 2004
    ..While tm-PTP epsilon related signaling pathways may figure in axon-glial interactions, interfering with tm-PTP epsilon activity does not perceptibly affect the development or myelinating capacity of most oligodendrocytes...

Research Grants16

  1. Characterization of Sox17 as a Regulator of Oligodendrocyte Cell Differentiation
    Vittorio Gallo; Fiscal Year: 2010
    ..Our proposed studies hope to shed light on crucial regulators of oligodendrocyte maturation that are potentially amenable to therapeutic intervention. ..
  2. MRDDRC at Children's National Medical Center
    Vittorio Gallo; Fiscal Year: 2007
    ..With the continued support of the MRDDRC, we expect to further enhance research productivity in the area of intellectual and other developmental disabilities. ..
  3. Characterization of Sox17 as a Regulator of Oligodendrocyte Cell Differentiation
    Vittorio Gallo; Fiscal Year: 2007
    ..Our proposed studies hope to shed light on crucial regulators of oligodendrocyte maturation that are potentially amenable to therapeutic intervention. ..
  4. A Common Glial-Neuronal Progenitor in Postnatal Brain
    Vittorio Gallo; Fiscal Year: 2007
    ..abstract_text> ..
  5. Postdoctoral Training in Developmental Disabilities Research
    Vittorio Gallo; Fiscal Year: 2007
    ..Each trainee will be carefully mentored through the program to ensure that he/she fully exploits the range of opportunities of the program. ..
  6. Hippocampal GABAergic Neurons from Progenitor Grafts
    Vittorio Gallo; Fiscal Year: 2006
    ..Altogether, these studies will define a novel experimental paradigm aimed at repairing hippocampal GABAergic intemeuron damage in various pathological states, such as epilepsy, stroke, and ischemia ..
  7. Novel Regulator of Oligodendrocyte Progenitor Migration
    Vittorio Gallo; Fiscal Year: 2006
    ..Our studies will: i) define a role for ET-1 and ET-Rs as migratory signals in oligodendrocyte development, and ii) determine whether novel means of enhancing OP migration could be explored to facilitate myelin repair. ..
  8. A Common Glial-Neuronal Progenitor in Postnatal Brain
    Vittorio Gallo; Fiscal Year: 2010
    ..abstract_text> ..