Janet A Englund
Affiliation: Children's Hospital and Regional Medical Center
- A comparison of 2 influenza vaccine schedules in 6- to 23-month-old childrenJanet A Englund
Division of Pediatric Infectious Diseases, Allergy, and Rheumatology, University of Washington and Children s Hospital and Regional Medical Center, Seattle, Washington 98105, USA
Pediatrics 115:1039-47. 2005..Trivalent inactivated influenza vaccine (TIV) is recommended for all children ages 6 to 23 months. Delivering 2 doses of TIV at least 4 weeks apart to young children receiving this vaccine for the first time is challenging...
- Respiratory virus pneumonia after hematopoietic cell transplantation (HCT): associations between viral load in bronchoalveolar lavage samples, viral RNA detection in serum samples, and clinical outcomes of HCTAngela P Campbell
Department of Pediatrics, University of Washington, Seattle, Washington, USA
J Infect Dis 201:1404-13. 2010..Few data exist on respiratory virus quantitation in lower respiratory samples and detection in serum from hematopoietic cell transplant (HCT) recipients with respiratory virus-associated pneumonia...
- Self-collection of foam nasal swabs for respiratory virus detection by PCR among immunocompetent subjects and hematopoietic cell transplant recipientsAngela P Campbell
University of Washington, Seattle, Washington, USA
J Clin Microbiol 51:324-7. 2013..004), respectively, and those from 140 URI samples from hematopoietic cell transplantation recipients were 88% and 85% (P = 0.56), respectively...
- WU and KI polyomaviruses in respiratory samples from allogeneic hematopoietic cell transplant recipientsJane Kuypers
University of Washington, Seattle, Washington 98102, USA
Emerg Infect Dis 18:1580-8. 2012..There were no associations with polyomavirus detection and acute graft versus host disease, cytomegalovirus reactivation, neutropenia, lymphopenia, hospitalization, or death...
- Antiviral therapy of respiratory viruses in haematopoietic stem cell transplant recipientsChristian Renaud
Seattle Children s Hospital, Seattle, WA, USA
Antivir Ther 17:175-91. 2012..Finally, new drugs have been developed to treat influenza virus, respiratory syncytial virus, parainfluenza virus and adenovirus with some promising results...
- Clinical disease and viral load in children infected with respiratory syncytial virus or human metapneumovirusEmily T Martin
Children s Hospital and Regional Medical Center, Seattle, WA 98105, USA
Diagn Microbiol Infect Dis 62:382-8. 2008..Our study has described a significant relationship between viral load and markers of disease severity for both RSV and hMPV in a large population of children evaluated for respiratory disease...
- Differences in clinical outcomes after 2009 influenza A/H1N1 and seasonal influenza among hematopoietic cell transplant recipientsSu Mi Choi
Vaccine and Infectious Disease Division, Fred Hutchinson Cancer Research Center, Seattle, WA, USA
Blood 117:5050-6. 2011..Thus, our data suggest that infection with 2009 influenza A/H1N1 resulted in more severe respiratory disease in HCT recipients compared with seasonal influenza...
- H275Y mutant pandemic (H1N1) 2009 virus in immunocompromised patientsChristian Renaud
Fred Hutchinson Cancer Research Center, Seattle, Washington, USA
Emerg Infect Dis 17:653-60; quiz 765. 2011..Emergence of oseltamivir resistance is frequent in immunocompromised patients infected with pandemic (H1N1) 2009 virus and can be associated with a wide range of clinical disease and viral kinetics...
- Frequent and prolonged shedding of bocavirus in young children attending daycareEmily T Martin
Center for Clinical and Translational Research, Seattle Children s Research Institute, 1900 Ninth Avenue, Seattle, WA 98101, USA
J Infect Dis 201:1625-32. 2010..Little is known about human bocavirus (HBoV) persistence and shedding and the association between HBoV detection and the onset and resolution of respiratory symptoms...
- Immunization with trivalent inactivated influenza vaccine in partially immunized toddlersJanet A Englund
Pediatric ID, Children s Hospital and Regional Medical Center, 4800 Sand Point Way, NE W8851, Seattle, Washington 98105, USA
Pediatrics 118:e579-85. 2006....
- Safety and immunogenicity of trivalent inactivated influenza vaccine in infants: a randomized double-blind placebo-controlled studyJanet A Englund
Department of Pediatrics, Division of Infectious Diseases, Children s Hospital Research Institute, University of Washington, Seattle, WA, USA
Pediatr Infect Dis J 29:105-10. 2010..Infants less than 6 months of age are at high risk for influenza disease and influenza-related complications, but no vaccine is licensed for this population...
- Emerging oseltamivir resistance in seasonal and pandemic influenza A/H1N1Christian Renaud
Fred Hutchinson Cancer Research Center, Seattle, WA 98109 1024, USA
J Clin Virol 52:70-8. 2011..However, immunocompromised patients infected with oseltamivir-resistant H1N1 experience potentially more risks of complication and transmissibility with few therapeutic options...
- Development of a symptom score for clinical studies to identify children with a documented viral upper respiratory tract infectionJames A Taylor
Department of Pediatrics, University of Washington, Seattle, WA 98195, USA
Pediatr Res 68:252-7. 2010..9%, and accuracy of 73.3%. Parental impression is only a moderately accurate predictor of viral URI in children. Our URI symptom score provided a more accurate method for identifying children with viral URIs for clinical studies...
- Emergence of oseltamivir-resistant pandemic H1N1 in an immunocompetent child with severe status asthmaticusChristian Renaud
Infectious Diseases Division, Fred Hutchinson Cancer Research Center, Seattle, WA, USA
J Asthma 48:572-5. 2011..Pandemic influenza A (H1N1) may cause severe illness in pediatric patient with chronic lung disease...
- Hospital-based influenza vaccination of children: an opportunity to prevent subsequent hospitalizationDanielle M Zerr
Children s Research Institute, and Children s Hospital and Regional Medical Center, Seattle, WA 98105, USA
Pediatrics 121:345-8. 2008..We performed this study to determine the frequency of previous hospitalization among children hospitalized with influenza...
- Multiple viral respiratory pathogens in children with bronchiolitisHilary E Stempel
Seattle Children s Hospital Research Institute, University of Washington, Seattle, WA, USA
Acta Paediatr 98:123-6. 2009..The aim of the study was to describe the frequency of viral pathogens and relative frequency of co-infections in nasal specimens obtained from young children with bronchiolitis receiving care at a children's hospital...
- Outcomes and duration of Pneumocystis jiroveci pneumonia therapy in infants with severe combined immunodeficiencyIngrid S Lundgren
Division of Infectious Diseases, Seattle Children s Hospital, Seattle, WA 98105, USA
Pediatr Infect Dis J 31:95-7. 2012..We found that 80% of patients receiving only 21 days of antibiotics survived to 12 months beyond hematopoietic cell transplant, whereas only 25% of patients who required longer treatment for PCP survived to stem cell engraftment...
- Human rhinovirus and coronavirus detection among allogeneic hematopoietic stem cell transplantation recipientsFilippo Milano
Fred Hutchinson Cancer Research Center, Seattle, WA, USA
Blood 115:2088-94. 2010..HRV and HCoV infections are common in the first 100 days after HCT, viral shedding lasts more than 3 weeks in half, and lower respiratory infection is rare...
- BK nephropathy in pediatric hematopoietic stem cell transplant recipientsPriya S Verghese
Department of Pediatrics, University of Washington and Seattle Children s Hospital, Seattle, WA 98105, USA
Pediatr Transplant 13:913-8. 2009....
- Prevalence and mechanisms of broad-spectrum beta-lactam resistance in Enterobacteriaceae: a children's hospital experienceXuan Qin
Department of Laboratory Medicine, Microbiology Laboratory, Children s Hospital and Regional Medical Center, NE, Seattle, WA 98105 0371, USA
Antimicrob Agents Chemother 52:3909-14. 2008..These data have important implications for empirical antimicrobial strategies targeting serious pediatric infections. Further study of this problem is warranted...
- Influenza-associated morbidity in children with cancerSarah K Tasian
Department of Pediatrics, University of Washington and Children s Hospital and Regional Medical Center, Seattle, Washington 98105, USA
Pediatr Blood Cancer 50:983-7. 2008..The clinical impact of influenza in children undergoing therapy for cancer is not well-described in the literature...
- Maternal immunization with inactivated influenza vaccine: rationale and experienceJanet A Englund
Department of Pediatrics, Children's Hospital and Regional Medical Center, University of Washington, 4800 Sand Point Way NE # 8G, Seattle, WA 98105, USA
Vaccine 21:3460-4. 2003..Increased influenza vaccine use during pregnancy has the potential to benefit both the woman and her infant...
- Pertussis immunization in the global pertussis initiative North American region: recommended strategies and implementation considerationsTina Tan
Division of Infectious Diseases, Northwestern University s Feinberg School of Medicine, The Children s Memorial Hospital, Chicago, IL 60614, USA
Pediatr Infect Dis J 24:S83-6. 2005....
- Influenza vaccine immunogenicity in 6- to 23-month-old children: are identical antigens necessary for priming?Emmanuel B Walter
Duke Clinical Research Institute, Department of Pediatrics, Duke University Medical Center, Durham, North Carolina, USA
Pediatrics 118:e570-8. 2006....
- Influenza vaccine for young children: two doses are better than oneKathleen Maletic Neuzil
J Pediatr 149:737-8. 2006
- Effectiveness of school-based influenza vaccinationJames C King
Department of Pediatrics, University of Maryland School of Medicine, 737 W Lombard St, Baltimore, MD 21201, USA
N Engl J Med 355:2523-32. 2006..Vaccination of children in school is one strategy to reduce the spread of influenza in households and communities...
- Antiviral therapy of influenzaJanet A Englund
Department of Pediatrics, University of Chicago, Chicago, IL 60637, USA
Semin Pediatr Infect Dis 13:120-8. 2002..No direct comparisons of any of these antiviral agents has been performed; all result in clinical improvement approximately 1 to 2 days earlier in otherwise healthy children when therapy is initiated within 48 hours of onset of symptoms...