William J Duddy

Summary

Affiliation: Children's National Medical Center
Country: USA

Publications

  1. pmc The isolated muscle fibre as a model of disuse atrophy: characterization using PhAct, a method to quantify f-actin
    William J Duddy
    Center for Genetic Medicine, Children s Research Institute, Children s National Medical Center, Washington, DC, USA
    Exp Cell Res 317:1979-93. 2011
  2. pmc Atmospheric oxygen tension slows myoblast proliferation via mitochondrial activation
    Stephanie Duguez
    Research Center for Genetic Medicine, Children s National Medical Center, Washington, District of Columbia, United States of America
    PLoS ONE 7:e43853. 2012

Collaborators

  • Stephanie Duguez
  • Viola Gnocchi
  • Terence A Partridge
  • Sherry Dadgar
  • James Bowe

Detail Information

Publications2

  1. pmc The isolated muscle fibre as a model of disuse atrophy: characterization using PhAct, a method to quantify f-actin
    William J Duddy
    Center for Genetic Medicine, Children s Research Institute, Children s National Medical Center, Washington, DC, USA
    Exp Cell Res 317:1979-93. 2011
    ..With this novel method we can distinguish those features and mechanisms of atrophy and hypertrophy that are intrinsic to the muscle fibre from those that include activities of other tissues and systemic agents...
  2. pmc Atmospheric oxygen tension slows myoblast proliferation via mitochondrial activation
    Stephanie Duguez
    Research Center for Genetic Medicine, Children s National Medical Center, Washington, District of Columbia, United States of America
    PLoS ONE 7:e43853. 2012
    ..Myoblast proliferation is also inhibited by the ~20% oxygen level used in standard tissue culture. We hypothesize that mitochondrial activity would be greater at hyperoxia (20% O(2)) relative to more physiological oxygen (5% O(2))...