- The isolated muscle fibre as a model of disuse atrophy: characterization using PhAct, a method to quantify f-actinWilliam J Duddy
Center for Genetic Medicine, Children s Research Institute, Children s National Medical Center, Washington, DC, USA
Exp Cell Res 317:1979-93. 2011..With this novel method we can distinguish those features and mechanisms of atrophy and hypertrophy that are intrinsic to the muscle fibre from those that include activities of other tissues and systemic agents...
- Atmospheric oxygen tension slows myoblast proliferation via mitochondrial activationStephanie Duguez
Research Center for Genetic Medicine, Children s National Medical Center, Washington, District of Columbia, United States of America
PLoS ONE 7:e43853. 2012..Myoblast proliferation is also inhibited by the ~20% oxygen level used in standard tissue culture. We hypothesize that mitochondrial activity would be greater at hyperoxia (20% O(2)) relative to more physiological oxygen (5% O(2))...