Research Topics
| John M CostelloSummaryAffiliation: Children's Hospital Country: USA Publications
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Detail Information
Publications
Steroid use before pediatric cardiac operations using cardiopulmonary bypass: an international survey of 36 centersPaul A Checchia
Division of Critical Care Medicine, Department of Pediatrics, Washington University School of Medicine, St. Louis Children's Hospital, St. Louis, MO, USA
Pediatr Crit Care Med 6:441-4. 2005..The inconsistencies in these data and the pediatric literature would support the undertaking of a large, multiple-center clinical trial to evaluate the risks and benefits of steroid administration before pediatric cardiopulmonary bypass...
Risk factors for central line-associated bloodstream infection in a pediatric cardiac intensive care unitJohn M Costello
Department of Cardiology, Children s Hospital Boston, Harvard Medical School, Boston, MA, USA
Pediatr Crit Care Med 10:453-9. 2009..To identify risk factors for central line-associated bloodstream infection (BSI) in patients receiving care in a pediatric cardiac intensive care unit...
Birth before 39 weeks' gestation is associated with worse outcomes in neonates with heart diseaseJohn M Costello
Department of Cardiology, Children s Hospital Boston, Harvard Medical School, Boston, MA, USA
Pediatrics 126:277-84. 2010..We sought to determine if a similar association exists between gestational age at delivery and adverse outcomes in neonates with critical congenital heart disease, with particular interest in those born at 37 to 38 weeks' gestation...
Risk factors for surgical site infection after cardiac surgery in childrenJohn M Costello
Department of Cardiology, Children s Hospital Boston, Harvard Medical School, Boston, Massachusetts 02115 5737, USA
Ann Thorac Surg 89:1833-41; discussion 1841-2. 2010..We sought to identify risk factors for surgical site infections (SSI) in children undergoing cardiac surgery...
Lyme carditis in children: presentation, predictive factors, and clinical courseJohn M Costello
Harvard Medical School, Division of Cardiac Intensive Care, Department of Cardiology, Children s Hospital Boston, 300 Longwood Ave, Bader 600, Boston, MA 02115, USA
Pediatrics 123:e835-41. 2009..We sought to identify predictive factors for Lyme carditis in children and to characterize the clinical course of these patients...
Systematic intervention to reduce central line-associated bloodstream infection rates in a pediatric cardiac intensive care unitJohn M Costello
Division of Cardiac Intensive Care, Department of Cardiology, Children s Hospital Boston, Harvard Medical School, Boston, MA 02115, USA
Pediatrics 121:915-23. 2008..Our goal was to determine whether an intervention involving staff education, increased awareness, and practice changes would decrease central line-associated bloodstream infection rates in a pediatric cardiac ICU...
Effect of cardiopulmonary bypass and surgical intervention on the natriuretic hormone system in childrenJohn M Costello
Division of Cardiology, Children s Memorial Hospital, The Feinberg School of Medicine at Northwestern University, Chicago, Ill, USA
J Thorac Cardiovasc Surg 130:822-9. 2005..We sought to determine the effect of cardiopulmonary bypass and surgical intervention on the natriuretic hormone system in children and to assess whether such changes are associated with morbidity...
Tight glycemic control versus standard care after pediatric cardiac surgeryMichael S D Agus
Boston Children s Hospital and Harvard Medical School, Boston, MA 02115, USA
N Engl J Med 367:1208-19. 2012..We tested the hypothesis that tight glycemic control reduces morbidity after pediatric cardiac surgery...
Association between intraoperative and early postoperative glucose levels and adverse outcomes after complex congenital heart surgeryAngelo Polito
Department of Cardiology, Children s Hospital Boston, Harvard Medical School, Boston, MA 02115, USA
Circulation 118:2235-42. 2008..This study sought to determine whether associations exist between perioperative glucose exposure, prolonged hospitalization, and morbid events after complex congenital heart surgery...
Outcomes and risk factors for mortality in premature neonates with critical congenital heart diseaseHenry H Cheng
Department of Cardiology, Children s Hospital Boston, Harvard Medical School, Boston, MA, USA
Pediatr Cardiol 32:1139-46. 2011..Patients with lower Apgar scores who receive preintervention mechanical ventilation and undergo more complex procedures are at greatest risk...
Outcomes after bidirectional Glenn operation: Blalock-Taussig shunt versus right ventricle-to-pulmonary artery conduitLillian Lai
Department of Cardiology, Children s Hospital Boston, Boston, Massachusetts, USA
Ann Thorac Surg 83:1768-73. 2007..We evaluated bidirectional Glenn operation outcomes and compared the two groups to assess whether the type of Norwood operation influenced outcomes...
Quality of life of pediatric cardiac patients who previously required extracorporeal membrane oxygenationJohn M Costello
Department of Cardiology, Children s Hospital Boston, Harvard Medical School, Boston, MA, USA
Pediatr Crit Care Med 13:428-34. 2012..We sought to assess quality of life of pediatric cardiac extracorporeal membrane oxygenation survivors. We hypothesized that these patients would have decreased quality of life when compared to that of a general U.S. population sample...
Blood transfusion after pediatric cardiac surgery is associated with prolonged hospital stayJoshua W Salvin
Department of Cardiology, Children s Hospital Boston, and Department of Pediatrics, Harvard Medical School, Boston, Massachusetts 02115, USA
Ann Thorac Surg 91:204-10. 2011..Red blood cell transfusion is associated with morbidity and mortality among adults undergoing cardiac surgery. We aimed to evaluate the association of transfusion with morbidity among pediatric cardiac surgical patients...
Risk factors for central line-associated bloodstream infection in pediatric intensive care unitsMatthew C Wylie
From the Division of Critical Care Medicine, Department of Anesthesia, Children s Hospital Boston, Harvard Medical School, Boston, MA 02115, USA
Infect Control Hosp Epidemiol 31:1049-56. 2010..We sought to identify risk factors for central line-associated bloodstream infection (CLABSI) to describe children who might benefit from adjunctive interventions...
Perioperative factors associated with prolonged mechanical ventilation after complex congenital heart surgeryAngelo Polito
Division of Cardiac Intensive Care, Department of Cardiology, Children s Hospital Boston, Boston, MA, USA
Pediatr Crit Care Med 12:e122-6. 2011..To evaluate perioperative factors associated with prolonged mechanical ventilation in children undergoing complex cardiac surgery for congenital heart disease...
Unplanned reinterventions are associated with postoperative mortality in neonates with critical congenital heart diseaseMjaye L Mazwi
Department of Cardiology, Children s Hospital Boston, Harvard Medical School, Boston, Mass, USA
J Thorac Cardiovasc Surg 145:671-7. 2013....
Initial experience with fenoldopam after cardiac surgery in neonates with an insufficient response to conventional diureticsJohn M Costello
Division of Cardiac Intensive Care, Department of Cardiology, Children's Hospital Boston, Harvard Medical School, Boston, MA, USA
Pediatr Crit Care Med 7:28-33. 2006..This study is limited by its retrospective design and the possibility that urine output improved spontaneously during the treatment period. A randomized, placebo-controlled clinical trial will be required to confirm these findings...
Aprotinin reduces operative closure time and blood product use after pediatric bypassJohn M Costello
Division of Cardiology and Critical Care Medicine, Children's Memorial Hospital, Chicago, Illinois, USA
Ann Thorac Surg 75:1261-6. 2003..007). CONCLUSIONS: Aprotinin reduced operative closure time and blood product exposure in pediatric patients undergoing cardiopulmonary bypass who were 6 months of age or less or underwent a repeat sternotomy...
A review of the natriuretic hormone system's diagnostic and therapeutic potential in critically ill childrenJohn M Costello
Division of Cardiac Intensive Care, Department of Cardiology, Children's Hospital Boston and Harvard Medical School, Boston, MA, USA
Pediatr Crit Care Med 7:308-18. 2006....
Early postoperative outcomes in a series of infants with hypoplastic left heart syndrome undergoing stage I palliation operation with either modified Blalock-Taussig shunt or right ventricle to pulmonary artery conduitClifford L Cua
Department of Cardiology, Children's Hospital, Boston, MA, USA
Pediatr Crit Care Med 7:238-44. 2006..The primary advantage of the NW-RVPA procedure may be faster recovery following surgery and earlier discharge from the hospital...
Resting energy expenditure after Fontan surgery in children with single-ventricle heart defectsNilesh M Mehta
Division of Critical Care Medicine Anesthesia, Department of Anesthesiology, Pain and Perioperative Medicine, Children s Hospital Boston, Harvard Medical School, Bader 634, MSICU Office, 300 Longwood Ave, Boston, MA 02115, USA
JPEN J Parenter Enteral Nutr 36:685-92. 2012..Data on resting energy expenditure (REE) and oxygen consumption (VO(2)) after pediatric cardiopulmonary bypass (CPB) will facilitate optimal nutrient prescription...
Intermediate-term outcomes after paediatric cardiac extracorporeal membrane oxygenation--what is known (and unknown)John M Costello
Children s Memorial Hospital, Feinberg School of Medicine, Northwestern University, 2300 Children s Plaza, Chicago, IL 60614, USA
Cardiol Young 21:118-23. 2011..However, programmatic efforts to improve the selection of patients and the preservation of the function of end organs during extracorporeal membrane oxygenation are clearly needed in order to improve long-term outcomes...
Images in cardiovascular medicine. Left ventricular outflow tract obstruction secondary to a rhabdomyomaJohn M Costello
Division of Cardiology, Children's Memorial Hospital, The Feinberg School of Medicine at Northwestern University, Chicago, Ill 60614-3394, USA
Circulation 107:1066-7. 2003
Real-time continuous glucose monitoring in pediatric patients during and after cardiac surgeryHannah G Piper
Department of Surgery, Children's Hospital Boston, Harvard Medical School, Boston, Massachusetts 02115, USA
Pediatrics 118:1176-84. 2006..Subcutaneous sensors performed well in the setting of hypothermia, inotrope use, and edema. These sensors facilitate identifying and following the effects of interventions to control blood glucose...
Minimizing complications associated with percutaneous central venous catheter placement in children: recent advancesJohn M Costello
Department of Pediatrics, Ann and Robert H Lurie Children s Hospital of Chicago, Chicago, IL, USA
Pediatr Crit Care Med 14:273-83. 2013....
A comparison of intravascular ultrasound with coronary angiography for evaluation of transplant coronary disease in pediatric heart transplant recipientsJohn M Costello
Division of Cardiology, Child Health Research Core, Children's Memorial Institute for Education and Research, Chicago, Illinois, USA
J Heart Lung Transplant 22:44-9. 2003..Prospective, multicenter studies are needed to best utilize intravascular ultrasound in this patient population...
Treatment of plastic bronchitis in a Fontan patient with tissue plasminogen activator: a case report and review of the literatureJohn M Costello
Division of Cardiology, Children's Memorial Hospital, Northwestern University Medical School, Chicago, Illinois 60614, USA
Pediatrics 109:e67. 2002..The literature is reviewed with emphasis placed on the occurrence of this disorder in patients with single ventricle physiology...
