Research Topics
Species | Steven D ColanSummaryAffiliation: Children's Hospital Country: USA Publications
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Publications
Midwall shortening after coarctation repair: the effect of through-plane motion on single-plane indices of left ventricular functionThomas L Gentles
Green Lane Paediatric and Congenital Cardiac Service, Starship Children s Hospital, Auckland, New Zealand
J Am Soc Echocardiogr 18:1131-6. 2005..After CoA, measures of left ventricular function systematically overestimate midwall fiber shortening unless the methodology accounts for through-plane motion...
Validation and re-evaluation of a discriminant model predicting anatomic suitability for biventricular repair in neonates with aortic stenosisSteven D Colan
Department of Cardiology, Children s Hospital, Harvard Medical School, Boston, Massachusetts 02115, USA
J Am Coll Cardiol 47:1858-65. 2006..The purpose of this study was to validate and re-evaluate our previously reported scoring systems for predicting optimal management in neonates with aortic stenosis (AS)...
Fetal aortic valve stenosis and the evolution of hypoplastic left heart syndrome: patient selection for fetal interventionKaarin Mäkikallio
Department of Cardiology, Children s Hospital, Harvard Medical School, Boston, MA, USA
Circulation 113:1401-5. 2006..The aim of this study was to define echocardiographic features associated with progression of midgestation fetal AS to HLHS...
Left ventricular diastolic function in children and young adults with congenital aortic valve diseaseKevin G Friedman
Department of Cardiology, Children s Hospital Boston and Department of Pediatrics, Harvard Medical School, Boston, Massachusetts, USA
Am J Cardiol 111:243-9. 2013..In conclusion, DD is common in young patients with AS and AS+AR but not in those with pure AR. A greater LV mass and previous aortic valve dilation were associated with DD...
Surgical aortic valvuloplasty in children and adolescents with aortic regurgitation: acute and intermediate effects on aortic valve function and left ventricular dimensionsEmile A Bacha
Department of Cardiac Surgery, Children s Hospital Boston and Harvard Medical School, Boston, Mass 02115, USA
J Thorac Cardiovasc Surg 135:552-9, 559.e1-3. 2008..Surgical aortic valvuloplasty is increasingly employed in the management of children and adolescents with aortic regurgitation, but the durability of this approach and factors associated with outcome are not well defined...
Report from The International Society for Nomenclature of Paediatric and Congenital Heart Disease: cardiovascular catheterisation for congenital and paediatric cardiac disease (Part 1 - Procedural nomenclature)Lisa Bergersen
Department of Cardiology, Children s Hospital Boston, 300 Longwood Avenue, Boston, MA 02115, USA
Cardiol Young 21:252-9. 2011..Part 2 will cover the nomenclature of complications associated with interventional cardiology as treatment for paediatric and congenital cardiac disease...
Reproducibility of echocardiographic diagnosis of left ventricular noncompactionSusan F Saleeb
Department of Cardiology, Children s Hospital Boston, Harvard Medical School, Boston, Massachusetts 02115, USA
J Am Soc Echocardiogr 25:194-202. 2012..Limited studies exist on the reproducibility of diagnosing LVNC...
An echocardiographic model predicting severity of aortic regurgitation in congenital heart diseaseRebecca S Beroukhim
Department of Cardiology, Children s Hospital Boston, Boston, MA 02115, USA
Circ Cardiovasc Imaging 3:542-9. 2010....
Fetal tricuspid valve size and growth as predictors of outcome in pulmonary atresia with intact ventricular septumJoshua W Salvin
Department of Cardiology, Cardiac ICU Office, Farley 6, Children s Hospital Boston, 300 Longwood Ave, Boston, Massachusetts 02115, USA
Pediatrics 118:e415-20. 2006..The objective of this study was to determine whether the size and rate of growth of the fetal tricuspid valve predict neonatal anatomy and biventricular repair...
Association of left ventricular dilation at listing for heart transplant with postlisting and early posttransplant mortality in children with dilated cardiomyopathyTajinder P Singh
Department of Cardiology, Children s Hospital Boston, Boston, Mass, USA
Circ Heart Fail 2:591-8. 2009....
Subtle abnormalities in contractile function are an early manifestation of sarcomere mutations in dilated cardiomyopathyNeal K Lakdawala
Brigham and Women s Hospital, 75 Francis Street, Boston, MA 02115, USA
Circ Cardiovasc Genet 5:503-10. 2012..By studying mutation carriers before a clinical diagnosis develops, we characterize the early manifestations of sarcomere mutations in DCM and investigate how these manifestations differ from sarcomere mutations associated with HCM...
Utility of exercise stress echocardiography in pediatric cardiac transplant recipients: a single-center experienceMing Hui Chen
Department of Cardiology, Children s Hospital Boston, 300 Longwood Ave, Boston, MA 02115, USA
J Heart Lung Transplant 31:517-23. 2012..Therefore, the aim of this study was to assess the feasibility and utility of ESE in excluding ANG-detected epicardial CAD at our center, where ESE has been implemented since 2007...
Epidemiology and cause-specific outcome of hypertrophic cardiomyopathy in children: findings from the Pediatric Cardiomyopathy RegistrySteven D Colan
Department of Cardiology, Children s Hospital, Harvard Medical School, Boston, Mass 02115, USA
Circulation 115:773-81. 2007..Current information on the epidemiology and outcomes of hypertrophic cardiomyopathy (HCM) in children is limited by disease diversity and small case series...
Correlation of exercise response in repaired coarctation of the aorta to left ventricular mass and geometryEric V Krieger
Department of Cardiology, Boston Children s Hospital, and Department of Pediatrics, Harvard Medical School, Boston, Massachusetts Cardiovascular Division, Brigham and Women s Hospital, and Department of Medicine, Harvard Medical School, Boston, Massachusetts Electronic address
Am J Cardiol 111:406-11. 2013..001). In conclusion, HRE was associated with increased LVMVR, even after adjusting for multiple covariates...
Left ventricular remodeling and improvement in diastolic function after balloon aortic valvuloplasty for congenital aortic stenosisKevin G Friedman
Department of Cardiology, Children s Hospital Boston and Harvard Medical School, Boston, MA 02115, USA
Circ Cardiovasc Interv 5:549-54. 2012..In congenital aortic stenosis, chronic pressure load has detrimental effects on left ventricular (LV) systolic and diastolic function. Reduction in LV pressure load with balloon aortic valvuloplasty (BAVP) may improve diastolic function...
Left heart growth, function, and reintervention after balloon aortic valvuloplasty for neonatal aortic stenosisDoff B McElhinney
Department of Cardiology, Children's Hospital, and Harvard Medical School, Boston, Mass 02115, USA
Circulation 111:451-8. 2005..Reintervention for residual/recurrent AS or iatrogenic AR is relatively common, particularly during the first year after BAVP, but aortic valve replacement during early childhood is seldom necessary...
Predictors of coronary artery visualization in Kawasaki diseaseRenee Margossian
Children s Hospital Boston and Harvard Medical School, Boston, Massachusetts 02115, USA
J Am Soc Echocardiogr 24:53-9. 2011..Small series have established high specificity and sensitivity for detecting abnormalities, yet visualization rates of individual CA segments and factors associated with success are unknown...
Relationship of magnetic resonance imaging estimation of myocardial iron to left ventricular systolic and diastolic function in thalassemiaBenedetta Leonardi
Department of Cardiology, Children s Hospital Boston, Department of Pediatrics, Harvard Medical School, Boston, Massachusetts 02115, USA
JACC Cardiovasc Imaging 1:572-8. 2008..We sought to evaluate whether echocardiographic diastolic function indices correlate with myocardial iron and systolic function in patients with transfusion-dependent thalassemia (TDT) who are at risk for cardiomyopathy...
Sudden unexpected death after balloon valvuloplasty for congenital aortic stenosisDavid W Brown
Department of Cardiology, Children s Hospital, Boston, Massachusetts 02115, USA
J Am Coll Cardiol 56:1939-46. 2010..The aims of this study were to determine the incidence and risk factors of sudden unexpected death (SUD) after balloon aortic valvuloplasty (BAVP) for congenital aortic stenosis (AS) and to assess the effect of exercise restriction...
Circulating matrix metalloproteinases in adolescents with hypertrophic cardiomyopathy and ventricular arrhythmiaJustin P Zachariah
Department of Cardiology, Children s Hospital Boston and Department of Pediatrics, Harvard Medical School, 300 Longwood Ave, Boston, MA 02115, USA
Circ Heart Fail 5:462-6. 2012..We explored differences in circulating markers of extracellular matrix turnover between young HCM patients with versus without history of serious arrhythmia...
Non-geometric echocardiographic indices of ventricular function in patients with a Fontan circulationJonathan Rhodes
Children Hospital Boston and Harvard Medical School, Boston, Massachusetts, USA
J Am Soc Echocardiogr 24:1213-9. 2011..The purpose of this study was to compare these nongeometric indices of ventricular function to cardiac magnetic resonance (CMR) measurements of ventricular ejection fraction (EF)...
Aortic translocation for the management of double-outlet right ventricle and pulmonary stenosis with dextrocardia: technique to avoid coronary insufficiencyVictor Bautista-Hernandez
Department of Cardiac Surgery, Children s Hospital Boston, Boston, Massachusetts 02115, USA
Ann Thorac Surg 89:633-5. 2010....
Comparison of echocardiographic and cardiac magnetic resonance imaging measurements of functional single ventricular volumes, mass, and ejection fraction (from the Pediatric Heart Network Fontan Cross-Sectional Study)Renee Margossian
Children s Hospital Boston and Harvard Medical School, Boston, Massachusetts, USA
Am J Cardiol 104:419-28. 2009..Echocardiographic and CMR measurements of FSV EF demonstrate similar interobserver reproducibility, whereas measurements of FSV mass and LV diastolic volume are more reproducible by CMR...
Cardiac magnetic resonance versus routine cardiac catheterization before bidirectional glenn anastomosis in infants with functional single ventricle: a prospective randomized trialDavid W Brown
Department of Cardiology, Children s Hospital Boston, 300 Longwood Ave, Boston, MA 02115, USA
Circulation 116:2718-25. 2007..Because catheterization is invasive and exposes patients to ionizing radiation, cardiac magnetic resonance (CMR) may be a safe and effective alternative...
Fetal diagnosis of interrupted aortic archMelanie Vogel
Department of Cardiology, Children s Hospital Boston, Boston, Massachusetts, USA
Am J Cardiol 105:727-34. 2010..Despite the diagnostic challenges, the frequency of prenatal diagnosis of the IAA is increasing...
Cardiac allograft function during the first year after transplantation in rejection-free children and young adultsFatima I Lunze
Departments of Cardiology, Boston Children s Hospital, Boston, MA 02115, USA
Circ Cardiovasc Imaging 5:756-64. 2012..We sought to assess the recovery of left (LV) and right ventricular (RV) function during the first year after HT in children and young adults using pulsed-wave tissue Doppler imaging...
Bicuspid aortic valve and associated aortic dilation in the youngSusan Fernandes
Department of Cardiology, Children s Hospital, Boston, MA 02115, USA
Heart 98:1014-9. 2012..Young patients with BAV can have significant aortic dilation that places them at risk for morbidity and mortality...
Changes in left atrioventricular valve geometry after surgical repair of complete atrioventricular canalElisabeth Kaza
Division of Cardiac Surgery and Cardiology, Children s Hospital Boston and Harvard Medical School, Boston, MA, USA
J Thorac Cardiovasc Surg 143:1117-24. 2012..We sought to determine the changes in left atrioventricular valve geometry after surgical repair that may predispose to regurgitation...
Echocardiographic predictors of mitral stenosis-related death or intervention in infantsElif Seda Selamet Tierney
Department of Cardiology, Children s Hospital Boston, Harvard Medical School, Boston, MA 02155, USA
Am Heart J 156:384-90. 2008..Among patients diagnosed with MS in early infancy, echocardiographic factors associated with MS-related intervention or death have not been determined...
The ventricular volume variability study of the Pediatric Heart Network: study design and impact of beat averaging and variable type on the reproducibility of echocardiographic measurements in children with chronic dilated cardiomyopathySteven D Colan
Children s Hospital Boston and Harvard Medical School, Boston, Massachusetts 02115, USA
J Am Soc Echocardiogr 25:842-854.e6. 2012....
Technical performance scores in congenital cardiac operations: a quality assessment initiativeJohn M Karamichalis
Department of Cardiac Surgery, Children s Hospital Boston and Harvard Medical School, Boston, Massachusetts, USA
Ann Thorac Surg 94:1317-23; discussion 1323. 2012..The purpose of this study was the development and implementation of a system for measuring technical performance in the majority of congenital cardiac operations to be used as a surgeon's self-assessment tool...
Myocardial fibrosis as an early manifestation of hypertrophic cardiomyopathyCarolyn Y Ho
Cardiovascular Division, Brigham and Women s Hospital, Boston, MA 02115, USA
N Engl J Med 363:552-63. 2010..In animal models, profibrotic genetic pathways are activated early, before hypertrophic remodeling. Data showing early profibrotic responses to sarcomere-gene mutations in patients with hypertrophic cardiomyopathy are lacking...
Improving outcomes in fetuses and neonates with congenital displacement (Ebstein's malformation) or dysplasia of the tricuspid valveDoff B McElhinney
Department of Cardiology, Children's Hospital Boston, Boston, Massachusetts, USA
Am J Cardiol 96:582-6. 2005..To improve outcomes in this group of high-risk patients, novel approaches to management may be indicated...
Challenges in echocardiographic assessment of mitral regurgitation in children after repair of atrioventricular septal defectAshwin Prakash
Department of Cardiology, Children s Hospital, Boston, MA 02115, USA
Pediatr Cardiol 33:205-14. 2012..The utility of regurgitant volume and fraction was severely limited by poor interobserver agreement and frequently negative values...
Electrocardiographic features of sarcomere mutation carriers with and without clinically overt hypertrophic cardiomyopathyNeal K Lakdawala
Cardiovascular Division, Brigham and Women s Hospital, Boston, Massachusetts, USA
Am J Cardiol 108:1606-13. 2011..However, owing to the limited sensitivity of ECG and echocardiographic screening, genetic testing is required to definitively identify at-risk family members...
Diastolic function in children with Kawasaki diseaseElif Seda Selamet Tierney
Department of Cardiology, Children s Hospital Boston, and Department of Pediatrics, Harvard Medical School, Boston, MA 02155, United States
Int J Cardiol 148:309-12. 2011..The purpose of this study was to determine whether diastolic function is impaired in KD patients and whether there are any clinical correlates...
Bicuspid aortic valve morphology and interventions in the youngSusan M Fernandes
Department of Cardiology, Children s Hospital, Department of Pediatrics, Harvard Medical School, Boston, Massachusetts 02115, USA
J Am Coll Cardiol 49:2211-4. 2007..The aim of this study was to determine whether the morphologic subtype of bicuspid aortic valve (BAV) is associated with valve intervention in the young...
Resource utilization after introduction of a standardized clinical assessment and management planKevin G Friedman
Department of Cardiology, Children s Hospital Boston and Department of Pediatrics, Harvard Medical School, Boston, MA 02115, USA
Congenit Heart Dis 5:374-81. 2010..Based on periodic review of systemically collected data the SCAMP is designed to be modified to improve its own algorithm. One of the objectives of a SCAMP is to identify and reduce resource utilization and patient care costs...
Noninvasive serial evaluation of myocardial mechanics in pressure overload hypertrophy of rabbit myocardiumAdrian M Moran
Department of Cardiology, Harvard Medical School, Boston, MA 02115, USA
Herz 28:52-62. 2003..CONCLUSIONS: This novel noninvasive method for determination of myocardial mechanics allows for serial evaluation of cardiac function and the determination of the time course from compensated hypertrophy to myocyte failure...
The longitudinal course of cardiomyopathy in Friedreich's ataxia during childhoodAlaina Kipps
Department of Cardiology, Boston, MA 02115, USA
Pediatr Cardiol 30:306-10. 2009..This study aimed to define the longitudinal course of the cardiac abnormalities with FA diagnosed during childhood and to correlate the presence of cardiomyopathy with clinical and genetic factors...
Adaptive mechanisms of left ventricular diastolic function to the physiologic load of pregnancyAdrian M Moran
Department of Cardiology, Children's Hospital, Harvard Medical School, Boston, Massachusetts 02115, USA
Clin Cardiol 25:124-31. 2002..Changes in heart rate, preload, and contractility, as well as stage of pregnancy influence this alteration...
Hypertrophic cardiomyopathy in childhoodSteven D Colan
Department of Cardiology, Children s Hospital Boston, 300 Longwood Avenue, Boston, MA 02115, USA
Heart Fail Clin 6:433-44, vii-iii. 2010..Although most of the available information concerning treatment and prevention of sudden death is derived in adults, management of children requires consideration of the differences in age-specific risk/benefit ratios...
Myocyte apoptosis occurs early during the development of pressure-overload hypertrophy in infant myocardiumYeong Hoon Choi
Department of Anesthesiology and Perioperative and Pain Medicine, Children s Hospital Boston, and Harvard Medical School, Boston, Mass 02115, USA
J Thorac Cardiovasc Surg 137:1356-62, 1362.e1-3. 2009..This study examined the hypothesis that myocyte loss occurs during compensatory hypertrophic growth in the developing infant myocardium subjected to progressive pressure overload...
Familial restrictive cardiomyopathy with skeletal abnormalitiesMarcy L Schwartz
Department of Cardiology, Children s Hospital, Boston, Massachusetts 02115, USA
Am J Cardiol 92:636-9. 2003..Consistent with the poor prognosis encountered for children with restrictive cardiomyopathy, 2 children in this family died, whereas a third was symptomatic by age 3 years...
Long-term predictors of aortic root dilation and aortic regurgitation after arterial switch operationMarcy L Schwartz
Department of Cardiology, Children s Hospital, 300 Longwood Avenue, Boston, Mass 02115, USA
Circulation 110:II128-32. 2004..Neo-aortic root dilation (ARD) and neo-aortic regurgitation (AR) may be progressive after arterial switch operation (ASO) for d-loop transposition of the great arteries (dTGA). We sought to identify predictors of ARD and AR after ASO...
Clinical outcomes and utility of cardiac catheterization prior to superior cavopulmonary anastomosisDavid W Brown
Department of Cardiology, Children s Hospital, Boston, MA 02115, USA
J Thorac Cardiovasc Surg 126:272-81. 2003....
Coronary artery dimensions in febrile children without Kawasaki diseaseJuan Carlos G Muniz
Department of Cardiology at Children s Hospital Boston, Boston, MA and the Department of Pediatrics, Harvard Medical School, Boston, MA, USA
Circ Cardiovasc Imaging 6:239-44. 2013..However, CA dimensions for febrile children are unknown. We compared CA dimensions in children with febrile illnesses other than KD to those of normal afebrile children and to KD patients...
A prospective phase II trial of vinblastine and methotrexate in multivessel intraluminal pulmonary vein stenosis in infants and childrenMaliha Rehman
Department of Cardiology, Children s Hospital, Boston, MA, USA
Congenit Heart Dis 6:608-23. 2011..To determine the safety and efficacy of the chemotherapeutic agents vinblastine and methotrexate in the treatment of children with progressive multivessel intraluminal pulmonary vein stenosis (PVS)...
Cardiac complications associated with the treatment of patients with congenital cardiac disease: consensus definitions from the Multi-Societal Database Committee for Pediatric and Congenital Heart DiseaseEmile Antoine Bacha
Department of Cardiac Surgery, Children s Hospital Boston and Harvard Medical School, Boston, Massachusetts 02115, USA
Cardiol Young 18:196-201. 2008..Clinicians caring for patients with congenital cardiac disease will be able to use this list for databases, quality improvement initiatives, reporting of complications, and comparing strategies for treatment...
Balloon dilation of severe aortic stenosis in the fetus: potential for prevention of hypoplastic left heart syndrome: candidate selection, technique, and results of successful interventionWayne Tworetzky
Department of Cardiology, Children s Hospital Boston, 300 Longwood Ave, Boston MA 02115, USA
Circulation 110:2125-31. 2004..Fetuses meeting the first criterion are undefined, and previous reports of fetal AS dilation have not evaluated the impact of intervention on in utero growth of left heart structures...
Endothelial pulse amplitude testing: feasibility and reproducibility in adolescentsElif Seda Selamet Tierney
Department of Cardiology, Children s Hospital, Boston, MA 02155, USA
J Pediatr 154:901-5. 2009..To test prospectively the reproducibility and feasibility of endothelial pulse amplitude testing (Endo-PAT), a novel Food and Drug Administration-approved technology, in healthy adolescents...
Accuracy of echocardiography in low birth weight infants with congenital heart diseaseAdam L Dorfman
Department of Cardiology, Children's Hospital Boston, 300 Longwood Ave, Boston, MA 02115, USA
Pediatrics 115:102-7. 2005..5 kg. As surgical and transcatheter interventions are extended to this population, heightened awareness of clinicians to pitfalls of echocardiography in this group of patients is warranted...
Echocardiographic assessment of the right ventricular response to hypertension in neonates on the basis of average-shaped contraction modelsEdward N Marcus
Department of Cardiology, Children's Hospital and the Department of Pediatrics, Harvard Medical School, Boston, USA
J Am Soc Echocardiogr 15:1145-53. 2002..CONCLUSION: Reconstructed-shape contraction models throughout 1 cardiac cycle identify altered patterns of RV contraction in the presence of pulmonary hypertension...
Report from The International Society for Nomenclature of Paediatric and Congenital Heart Disease: cardiovascular catheterisation for congenital and paediatric cardiac disease (Part 2 - Nomenclature of complications associated with interventional cardioloLisa Bergersen
Department of Cardiology, Children s Hospital Boston, 300 Longwood Avenue, Boston, MA 02115, USA
Cardiol Young 21:260-5. 2011..Part 2 will cover the nomenclature of complications associated with interventional cardiology as treatment for paediatric and congenital cardiac disease...
Familial dilated cardiomyopathy caused by an alpha-tropomyosin mutation: the distinctive natural history of sarcomeric dilated cardiomyopathyNeal K Lakdawala
Cardiovascular Division, Brigham and Women s Hospital, Boston, Massachusetts 02115, USA
J Am Coll Cardiol 55:320-9. 2010..We sought to further define the role of sarcomere mutations in dilated cardiomyopathy (DCM) and associated clinical phenotypes...
Rationale and design of a randomized clinical trial of beta-blocker therapy (atenolol) versus angiotensin II receptor blocker therapy (losartan) in individuals with Marfan syndromeRonald V Lacro
Children s Hospital Boston and Harvard Medical School, Boston, MA 02115, USA
Am Heart J 154:624-31. 2007..Recent studies in an FBN1-targeted mouse model of MFS with aortic disease similar to that seen in humans showed that treatment with losartan normalized aortic root growth and aortic wall architecture...
Evidence of adverse ventricular interdependence in patients with atrial septal defectsRoxanne E Walker
Department of Cardiology, Children's Hospital, 300 Longwood Avenue, Boston, MA 02115, USA
Am J Cardiol 93:1374-7, A6. 2004..Thus, LV dysfunction associated with RV volume overload is secondary to altered chamber geometry and decreased myofiber preload. This physiology is immediately reversible and is independent of heart rate and afterload...
Association between congenital cardiovascular malformations and neuroblastomaRani E George
Department of Pediatric Oncology, Dana Farber Cancer Institute, Harvard Medical School, Boston, Massachusetts, USA
J Pediatr 144:444-8. 2004..We explored the association between neuroblastoma and congenital cardiovascular malformations (CCM), previously described in case reports...
Morphology of bicuspid aortic valve in children and adolescentsSusan M Fernandes
Department of Cardiology, Children's Hospital, 300 Longwood Avenue, Boston, MA 02115, USA
J Am Coll Cardiol 44:1648-51. 2004....
Theoretical and empirical derivation of cardiovascular allometric relationships in childrenThierry Sluysmans
Dept. of Cardiology, Children's Hospital, 300 Longwood Avenue, Boston, MA 02115, USA
J Appl Physiol 99:445-57. 2005..Overall, the relationship between cardiac output and body size is the fundamental driving factor in cardiovascular allometry...
Donald Charles Fyler: 1924–2011Jane W Newburger
Department of Cardiology, Children s Hospital Boston, Harvard Medical School, Boston, Massachusetts, USA
Cardiol Young 21:485-9. 2011....
Cardiovascular disease: cause of morbidity and mortality in adult survivors of childhood cancersMing Hui Chen
Department of Cardiology, Children s Hospital Boston, 300 Longwood Ave, Boston, MA 02115, USA
Circ Res 108:619-28. 2011..Basic and translational research is urgently needed to clarify pathophysiologic mechanisms of late cardiac effects and to develop therapies to improve both long-term survival and quality of life of adults cured of pediatric cancers...
Recombinant human growth hormone treatment for dilated cardiomyopathy in childrenDoff B McElhinney
Department of Cardiology, Children s Hospital, 300 Longwood Ave, Boston, MA 02115, USA
Pediatrics 114:e452-8. 2004..We undertook this study to determine the effects of recombinant human GH on LV function and mass among children with stable LV dysfunction attributable to DCM...
Factors associated with establishing a causal diagnosis for children with cardiomyopathyGerald F Cox
Division of Genetics, Department of Medicine, Children's Hospital, Boston, Massachusetts, USA
Pediatrics 118:1519-31. 2006..Although not widely used, skeletal muscle biopsy may yield a cause for some patients with hypertrophic cardiomyopathy and for patients suspected of having a mitochondrial disorder...
Randomized trial of pulsed corticosteroid therapy for primary treatment of Kawasaki diseaseJane W Newburger
Department of Cardiology, Children s Hospital and Harvard Medical School, Boston, MA 02115, USA
N Engl J Med 356:663-75. 2007..Studies have suggested that primary corticosteroid therapy might be beneficial and that adverse events are infrequent with short-term use...
Serum cardiac troponin and subclinical cardiac status in pediatric chronic renal failureSteven E Lipshultz
Department of Cardiology, Children s Hospital, Boston, Massachusetts, USA
Pediatrics 112:79-86. 2003..Pediatric patients are ideal for studies of the relationship between uremia and heart disease because they are unlikely to have cardiac risk factors other than uremia...
Cardiovascular outcomes of pediatric seroreverters perinatally exposed to HAART: design of a longitudinal clinical studyJill E Lavigne
University of Rochester, Rochester, NY, USA
Cardiovasc Toxicol 4:187-97. 2004..The cohorts are similar in terms of gender and race and the recruited subjects are representative of all eligible subjects in terms of exposure to HAART. Recruitment will continue into 2006...
Cardiovascular status in long-term survivors of Hodgkin's disease treated with chest radiotherapyM Jacob Adams
Department of Community and Preventive Medicine, University of Rochester School of Medicine and Dentistry, NY, USA
J Clin Oncol 22:3139-48. 2004..We recommend serial, comprehensive cardiac screening of HD survivors who fit this profile...
Cardiac and clinical phenotype in Barth syndromeCarolyn T Spencer
Congenital Heart Center, University of Florida College of Medicine, PO Box 100296, Gainesville, FL 32610 0296, USA
Pediatrics 118:e337-46. 2006..We sought to evaluate extent of cardioskeletal myopathy, potential for arrhythmia, delays in growth, and biochemical correlates of disease severity in patients with this disorder...
Design of a large cross-sectional study to facilitate future clinical trials in children with the Fontan palliationLynn A Sleeper
New England Research Institutes, Watertown, MA 02472, USA
Am Heart J 152:427-33. 2006....
Usefulness of the pediatric electrocardiogram in detecting left ventricular hypertrophy: results from the Prospective Pediatric Pulmonary and Cardiovascular Complications of Vertically Transmitted HIV Infection (P2C2 HIV) multicenter studyShannon M Rivenes
Department of Pediatrics, Division of Pediatric Cardiology, Baylor College of Medicine Texas Children s Hospital, Houston, Tex 77030, USA
Am Heart J 145:716-23. 2003..This study prospectively assesses the usefulness of the pediatric ECG as a screening modality for LVH...
Incidence, causes, and outcomes of dilated cardiomyopathy in childrenJeffrey A Towbin
Texas Children's Hospital, Baylor College of Medicine, Houston, USA
JAMA 296:1867-76. 2006..Race, sex, and age affect the incidence of disease. Most children do not have a known cause of DCM, which limits the potential for disease-specific therapies...
Clinical features and outcomes of childhood dilated cardiomyopathy: results from a national population-based studyPiers E F Daubeney
Department of Cardiology, Royal Children's Hospital, Melbourne, Australia
Circulation 114:2671-8. 2006..CONCLUSIONS: Early mortality is high in childhood dilated cardiomyopathy, but the clinical status of long-term survivors is good. This population-based study identifies children at risk of adverse events...
Incidence of cardiac abnormalities in children with human immunodeficiency virus infection: The prospective P2C2 HIV studyThomas J Starc
Department of Pediatrics, Division of Pediatric Cardiology, Presbyterian Hospital/Columbia University, College of Physicians and Surgeons, New York City, New York, USA
J Pediatr 141:327-34. 2002..We recommend that HIV-infected children undergo routine echocardiographic surveillance for cardiac abnormalities...
Doxorubicin administration by continuous infusion is not cardioprotective: the Dana-Farber 91-01 Acute Lymphoblastic Leukemia protocolSteven E Lipshultz
Division of Pediatric Cardiology, Strong Children s Hospital and University of Rochester Medical Center, University of Rochester School of Medicine and Dentistry, Rochester, NY 14642, USA
J Clin Oncol 20:1677-82. 2002..We compared cardiac outcomes in children receiving bolus or continuous infusion of doxorubicin...
Wall stress misrepresents afterload in children and young adults with abnormal left ventricular geometryThomas L Gentles
Department of Paediatric Cardiology, Green Lane Hospital, Auckland 1003, New Zealand
J Appl Physiol 92:1053-7. 2002..001], with WS(es) underestimating FS(es) when h/D was increased and overestimating FS(es) when h/D was decreased. Analyses of myocardial mechanics based on wall stress have limited validity in patients with abnormal ventricular geometry...
Systolic and diastolic performance late after the Fontan procedure for a single ventricle and comparison of those undergoing operation at <12 months of age and at >12 months of ageOrnella Milanesi
Department of Pediatrics, University of Padova, Medical School, Padova, Italy
Am J Cardiol 89:276-80. 2002....
Mild dilated cardiomyopathy and increased left ventricular mass predict mortality: the prospective P2C2 HIV Multicenter StudyStacy D Fisher
Midatlantic Cardiology Associates, Baltimore, MD, USA
Am Heart J 150:439-47. 2005..Chronic mild depression of LV function and elevated LV mass were associated with higher all-cause mortality...
The current status and future directions of efforts to create a global database for the outcomes of therapy for congenital heart diseaseJeffrey P Jacobs
The Congenital Heart Institute of Florida, Petersburg, FL 33701, USA
Cardiol Young 15:190-7. 2005
Atrioventricular discordance with ventriculoarterial concordance: A remaining indication for the atrial switch operationIgor E Konstantinov
Division of Cardiovascular Surgery, Hospital for Sick Children, University of Toronto, 555 University Avenue, Toronto, Ontario, Canada
J Thorac Cardiovasc Surg 128:944-5. 2004
Contemporary outcomes after the Fontan procedure: a Pediatric Heart Network multicenter studyPage A W Anderson
Duke University Medical Center, Durham, North Carolina 27710, USA
J Am Coll Cardiol 52:85-98. 2008..We characterized a large cohort of children who had a Fontan procedure, with measures of functional health status, ventricular size and function, exercise capacity, heart rhythm, and brain natriuretic peptide (BNP)...
Characteristics and outcomes of cardiomyopathy in children with Duchenne or Becker muscular dystrophy: a comparative study from the Pediatric Cardiomyopathy RegistryDavid M Connuck
Janet Weis Children s Hospital, Geisinger Medical Center, Danville, PA, USA
Am Heart J 155:998-1005. 2008..The aim of this study was to determine in pediatric Duchenne (DMD) and Becker muscular dystrophy (BMD) or other dilated cardiomyopathies (ODCM) whether outcomes differ by diagnosis...
Cardiac changes associated with growth hormone therapy among children treated with anthracyclinesSteven E Lipshultz
Department of Pediatrics, Miller School of Medicine, University of Miami, Holtz Children s Hospital, Sylvester Comprehensive Cancer Center, Miami, Florida, USA
Pediatrics 115:1613-22. 2005..Anthracycline-treated childhood cancer survivors frequently have reduced left ventricular (LV) wall thickness and contractility, and GH therapy may affect these factors...
ACCF/AHA/AAP recommendations for training in pediatric cardiology. Task force 2: pediatric training guidelines for noninvasive cardiac imaging endorsed by the American Society of Echocardiography and the Society of Pediatric EchocardiographyStephen P Sanders
J Am Coll Cardiol 46:1384-8. 2005
Postmortem cardiomegaly and echocardiographic measurements of left ventricular size and function in children infected with the human immunodeficiency virus. The Prospective P2C2 HIV Multicenter StudyDebra L Kearney
Department of Pathology, Baylor College of Medicine, Houston, TX 77030, USA
Cardiovasc Pathol 12:140-8. 2003..We sought to determine the postmortem prevalence, clinicopathologic relationships and importance of cardiomegaly in HIV-infected children...
Turner syndrome is an independent risk factor for aortic dilation in the youngLeo Lopez
Children s Hospital at Montefiore, Division of Pediatric Cardiology, 3415 Bainbridge Ave, Rosenthal 3, Bronx, NY 10467, USA
Pediatrics 121:e1622-7. 2008....
Long-term enalapril therapy for left ventricular dysfunction in doxorubicin-treated survivors of childhood cancerSteven E Lipshultz
Division of Pediatric Cardiology, University of Rochester Medical Center, NY 14642, USA
J Clin Oncol 20:4517-22. 2002..We document the long-term effects of angiotensin-converting enzyme inhibitors in doxorubicin-treated survivors of childhood cancer...
Cardiovascular status of infants and children of women infected with HIV-1 (P(2)C(2) HIV): a cohort studySteven E Lipshultz
Division of Pediatric Cardiology, University of Rochester School of Medicine and Dentistry, Rochester, NY, USA
Lancet 360:368-73. 2002....
Prospective assessment after pediatric cardiac ablation: fate of intracardiac structure and function, as assessed by serial echocardiographyGeorge F Van Hare
The Department of Pediatrics, Division of Cardiology, Stanford University, Stanford, CA 94304, USA
Am Heart J 153:815-20, 820.e1-6. 2007..Catheter ablation puts cardiac valves at risk of damage, and children are of particular concern...
Tissue velocity Doppler assessment of atrial and ventricular electromechanical coupling and atrioventricular time intervals in normal subjectsAzaria J J T Rein
Division of Pediatric Cardiology, Hadassah Hebrew University Hospital, Jerusalem, Israel
Am J Cardiol 92:1347-50. 2003..Mechanical events and electromechanical coupling are analyzed simultaneously in the atria and ventricles using tissue velocity imaging. Normal values for these parameters are provided...
Cardiovascular trials in long-term survivors of childhood cancerSteven E Lipshultz
J Clin Oncol 22:769-73. 2004
The nomenclature, definition and classification of cardiac structures in the setting of heterotaxyJeffrey P Jacobs
The Congenital Heart Institute of Florida, All Children s Hospital Children s Hospital of Tampa, University of South Florida College of Medicine, Cardiac Surgical Associates, Saint Petersburg 33701, USA
Cardiol Young 17:1-28. 2007..It is only by utilizing this stepwise and logical progression of analysis that it becomes possible to describe correctly, and to classify properly, patients with heterotaxy...
The nomenclature, definition and classification of hypoplastic left heart syndromeChristo I Tchervenkov
Division of Pediatric Cardiovascular Surgery, The Montreal Children s Hospital of the McGill University Health Centre, Montreal, Quebec, Canada
Cardiol Young 16:339-68. 2006..We also present the crossmap of the associated terms for diagnoses and procedures, as recently completed by the Nomenclature Working Group...
Delayed diagnosis of Kawasaki disease: what are the risk factors?L Luann Minich
Primary Children s Medical Center, Salt Lake City, Utah, USA
Pediatrics 120:e1434-40. 2007....
Clinical utility of Doppler echocardiography in assessing aortic stenosis severity and predicting need for intervention in childrenAntonios P Vlahos
Child Health Department, Pediatric Cardiology Division, University of Ioannina, 45110 Ioannina, Greece
Pediatr Cardiol 29:507-14. 2008..The magnitude of overestimation was significantly lower from the apical window. In children with VAS, the best prediction of the catheterization gradient could be based on the average of MIGAP and MIGHP...
Evolving therapeutic strategies for dystrophinopathies: potential for conflict between cardiac and skeletal needsSteven D Colan
Circulation 112:2756-8. 2005
Classification of the functionally univentricular heart: unity from mapped codesJeffrey P Jacobs
The Congenital Heart Institute of Florida, All Children's Hospital, Children's Hospital of Tampa, University of South Florida, Cardiac Surgical Associates, Saint Petersburg, Florida 33701, USA
Cardiol Young 16:9-21. 2006
Chronic progressive cardiac dysfunction years after doxorubicin therapy for childhood acute lymphoblastic leukemiaSteven E Lipshultz
Department of Pediatrics D820, Miller School of Medicine at the University of Miami, Miami, FL 33101, USA
J Clin Oncol 23:2629-36. 2005..Cross-sectional studies show that cardiac abnormalities are common in long-term survivors of doxorubicin-treated childhood malignancies. Longitudinal data, however, are rare...
Improved outcomes of pediatric dilated cardiomyopathy with utilization of heart transplantationAnna E Tsirka
Department of Pediatrics, Washington University School of Medicine, St. Louis, Missouri, USA
J Am Coll Cardiol 44:391-7. 2004..Utilization of heart transplantation has led to improved survival after the diagnosis of pediatric DCM...
The effect of dexrazoxane on myocardial injury in doxorubicin-treated children with acute lymphoblastic leukemiaSteven E Lipshultz
Department of Pediatrics, University of Miami School of Medicine, Holtz Children s Hospital of the University of Miami Jackson Memorial Medical Center and the Sylvester Comprehensive Cancer Center, Miami 33101, USA
N Engl J Med 351:145-53. 2004..Doxorubicin chemotherapy is very effective in children with acute lymphoblastic leukemia (ALL) but also injures myocardial cells. Dexrazoxane, a free-radical scavenger, may protect the heart from doxorubicin-associated damage...
The nomenclature, definition and classification of discordant atrioventricular connectionsJeffrey P Jacobs
The Congenital Heart Institute of Florida CHIF, USA
Cardiol Young 16:72-84. 2006..The International Paediatric and Congenital Cardiac Code can be downloaded from the Internet, free of charge, at www.ipccc. net...
