M G Butler

Summary

Affiliation: Children's Mercy Hospital
Country: USA

Publications

  1. ncbi request reprint Behavioral differences among subjects with Prader-Willi syndrome and type I or type II deletion and maternal disomy
    Merlin G Butler
    Section of Medical Genetics and Molecular Medicine, Children s Mercy Hospitals and Clinics and University of Missouri Kansas City School of Medicine, Kansas City, Missouri 64108, USA
    Pediatrics 113:565-73. 2004
  2. ncbi request reprint Management of obesity in Prader-Willi syndrome
    Merlin G Butler
    Section of Medical Genetics and Molecular Medicine, Children s Mercy Hospitals and Clinics, and University of Missouri Kansas City School of Medicine, Kansas City, MO 64108, USA
    Nat Clin Pract Endocrinol Metab 2:592-3. 2006
  3. ncbi request reprint Plasma peptide YY and ghrelin levels in infants and children with Prader-Willi syndrome
    Merlin G Butler
    Section of Medical Genetics and Molecular Medicine, Children s Mercy Hospitals Kansas City, MO 64108, USA
    J Pediatr Endocrinol Metab 17:1177-84. 2004
  4. ncbi request reprint X-chromosome inactivation patterns in females with Prader-Willi syndrome
    Merlin G Butler
    Section of Medical Genetics and Molecular Medicine, Children s Mercy Hospitals and Clinics and University of Missouri, Kansas City School of Medicine, Kansas City, Missouri 64108, USA
    Am J Med Genet A 143:469-75. 2007
  5. pmc Subset of individuals with autism spectrum disorders and extreme macrocephaly associated with germline PTEN tumour suppressor gene mutations
    M G Butler
    Section of Medical Genetics and Molecular Medicine, Children s Mercy Hospitals and Clinics, University of Missouri Kansas City School of Medicine, Kansas City, MO, USA
    J Med Genet 42:318-21. 2005
  6. doi request reprint Array comparative genomic hybridization (aCGH) analysis in Prader-Willi syndrome
    Merlin G Butler
    Children s Mercy Hospitals and Clinics and University of Missouri Kansas City School of Medicine, Kansas City, Missouri 64108, USA
    Am J Med Genet A 146:854-60. 2008
  7. ncbi request reprint Coenzyme Q10 levels in Prader-Willi syndrome: comparison with obese and non-obese subjects
    Merlin G Butler
    Children s Mercy Hospitals and Clinics and University of Missouri Kansas City School of Medicine, Kansas City, Missouri 64108, USA
    Am J Med Genet A 119:168-71. 2003
  8. ncbi request reprint Imprinting disorders: non-Mendelian mechanisms affecting growth
    Merlin G Butler
    Section of Medical Genetics and Molecular Medicine, Children s Mercy Hospitals and Clinics and the University of Missouri Kansas City School of Medicine, Kansas City, MO 64108, USA
    J Pediatr Endocrinol Metab 15:1279-88. 2002
  9. ncbi request reprint Energy expenditure and physical activity in Prader-Willi syndrome: comparison with obese subjects
    Merlin G Butler
    Section of Medical Genetics and Molecular Medicine, Children s Mercy Hospitals and Clinics and University of Missouri Kansas City School of Medicine, Kansas City, Missouri 64108, USA
    Am J Med Genet A 143:449-59. 2007
  10. ncbi request reprint Thyroid function studies in Prader-Willi syndrome
    Merlin G Butler
    Section of Medical Genetics and Molecular Medicine, Children s Mercy Hospitals and Clinics and University of Missouri Kansas City School of Medicine, Kansas City, Missouri 64108, USA
    Am J Med Genet A 143:488-92. 2007

Collaborators

Detail Information

Publications52

  1. ncbi request reprint Behavioral differences among subjects with Prader-Willi syndrome and type I or type II deletion and maternal disomy
    Merlin G Butler
    Section of Medical Genetics and Molecular Medicine, Children s Mercy Hospitals and Clinics and University of Missouri Kansas City School of Medicine, Kansas City, Missouri 64108, USA
    Pediatrics 113:565-73. 2004
    ....
  2. ncbi request reprint Management of obesity in Prader-Willi syndrome
    Merlin G Butler
    Section of Medical Genetics and Molecular Medicine, Children s Mercy Hospitals and Clinics, and University of Missouri Kansas City School of Medicine, Kansas City, MO 64108, USA
    Nat Clin Pract Endocrinol Metab 2:592-3. 2006
  3. ncbi request reprint Plasma peptide YY and ghrelin levels in infants and children with Prader-Willi syndrome
    Merlin G Butler
    Section of Medical Genetics and Molecular Medicine, Children s Mercy Hospitals Kansas City, MO 64108, USA
    J Pediatr Endocrinol Metab 17:1177-84. 2004
    ....
  4. ncbi request reprint X-chromosome inactivation patterns in females with Prader-Willi syndrome
    Merlin G Butler
    Section of Medical Genetics and Molecular Medicine, Children s Mercy Hospitals and Clinics and University of Missouri, Kansas City School of Medicine, Kansas City, Missouri 64108, USA
    Am J Med Genet A 143:469-75. 2007
    ..Extreme X-inactivation skewness may also lead to additional risks for X-linked recessive disorders in PWS females with UPD and extreme X-chromosome skewness...
  5. pmc Subset of individuals with autism spectrum disorders and extreme macrocephaly associated with germline PTEN tumour suppressor gene mutations
    M G Butler
    Section of Medical Genetics and Molecular Medicine, Children s Mercy Hospitals and Clinics, University of Missouri Kansas City School of Medicine, Kansas City, MO, USA
    J Med Genet 42:318-21. 2005
    ..We suggest that PTEN gene testing be considered for patients with autistic behaviour and extreme macrocephaly. The gene findings may impact on recurrence risks as well as medical management for the patient...
  6. doi request reprint Array comparative genomic hybridization (aCGH) analysis in Prader-Willi syndrome
    Merlin G Butler
    Children s Mercy Hospitals and Clinics and University of Missouri Kansas City School of Medicine, Kansas City, Missouri 64108, USA
    Am J Med Genet A 146:854-60. 2008
    ..Furthermore, most PWS subjects had copy number variation (CNV) of 50 kb or larger in other chromosome regions; most common were deletions and duplications of 8p and 3q, previously recognized sites of CNV in the human genome...
  7. ncbi request reprint Coenzyme Q10 levels in Prader-Willi syndrome: comparison with obese and non-obese subjects
    Merlin G Butler
    Children s Mercy Hospitals and Clinics and University of Missouri Kansas City School of Medicine, Kansas City, Missouri 64108, USA
    Am J Med Genet A 119:168-71. 2003
    ..However, a lower muscle mass was found in the PWS subjects...
  8. ncbi request reprint Imprinting disorders: non-Mendelian mechanisms affecting growth
    Merlin G Butler
    Section of Medical Genetics and Molecular Medicine, Children s Mercy Hospitals and Clinics and the University of Missouri Kansas City School of Medicine, Kansas City, MO 64108, USA
    J Pediatr Endocrinol Metab 15:1279-88. 2002
    ..Several of these disorders are discussed and illustrated...
  9. ncbi request reprint Energy expenditure and physical activity in Prader-Willi syndrome: comparison with obese subjects
    Merlin G Butler
    Section of Medical Genetics and Molecular Medicine, Children s Mercy Hospitals and Clinics and University of Missouri Kansas City School of Medicine, Kansas City, Missouri 64108, USA
    Am J Med Genet A 143:449-59. 2007
    ..Our data indicate that there is a significant reduction of EE in individuals with PWS resulting from reduced activity but also from lower energy utilization due to reduced LBM which consists primarily of muscle...
  10. ncbi request reprint Thyroid function studies in Prader-Willi syndrome
    Merlin G Butler
    Section of Medical Genetics and Molecular Medicine, Children s Mercy Hospitals and Clinics and University of Missouri Kansas City School of Medicine, Kansas City, Missouri 64108, USA
    Am J Med Genet A 143:488-92. 2007
  11. ncbi request reprint Plasma obestatin and ghrelin levels in subjects with Prader-Willi syndrome
    Merlin G Butler
    Section of Medical Genetics and Molecular Medicine, Children s Mercy Hospitals and Clinics and University of Missouri Kansas City School of Medicine, Kansas City, Missouri 64108, USA
    Am J Med Genet A 143:415-21. 2007
    ..The possibility that obestatin may contribute to the failure to thrive which is common in infants with PWS warrants further investigation...
  12. ncbi request reprint Decreased bone mineral density in Prader-Willi syndrome: comparison with obese subjects
    M G Butler
    Section of Medical Genetics and Molecular Medicine, Children s Mercy Hospitals and Clinics and University of Missouri Kansas City School of Medicine, Kansas City, Missouri 64108, USA
    Am J Med Genet 103:216-22. 2001
    ..It may not be caused by loss, or active degradation, of bone matrix measurable by the methods described in this study further supporting the possible need for hormone therapy during adolescence...
  13. ncbi request reprint Plasma cholecystokinin levels in Prader-Willi syndrome and obese subjects
    M G Butler
    Children s Mercy Hospitals and Clinics, Kansas City, Missouri 64108, USA
    Am J Med Genet 95:67-70. 2000
    ..These results suggest that differences in the peripheral CCK response to FFA levels may be a factor contributing to the altered satiety response in PWS subjects...
  14. ncbi request reprint Specific genetic diseases at risk for sedation/anesthesia complications
    M G Butler
    Section of Medical Genetics and Molecular Medicine, Children s Mercy Hospitals and Clinics, Kansas City, Missouri 64108, USA
    Anesth Analg 91:837-55. 2000
    ..Recommendations for presedation evaluation and checklist items are given that may impact on the delivery of care for these patients...
  15. ncbi request reprint Insulin resistance and obesity-related factors in Prader-Willi syndrome: comparison with obese subjects
    Z Talebizadeh
    Section of Medical Genetics and Molecular Medicine, Children s Mercy Hospitals and Clinics, University of Missouri Kansas City School of Medicine, Kansas City, MO 64108, USA
    Clin Genet 67:230-9. 2005
    ..PWS subjects with increased VFA may be at a higher risk of obesity-related complications compared to PWS subjects without increased VFA...
  16. pmc Microarray analysis of gene/transcript expression in Prader-Willi syndrome: deletion versus UPD
    D C Bittel
    Section of Medical Genetics and Molecular Medicine, Children s Mercy Hospitals and Clinics and University of Missouri Kansas City School of Medicine, Kansas City, MO 64108, USA
    J Med Genet 40:568-74. 2003
    ..There is a paucity of data examining simultaneous gene expression in this syndrome...
  17. doi request reprint Analysis of the Prader-Willi syndrome chromosome region using quantitative microsphere hybridization (QMH) array
    H L Newkirk
    Genomics Research Laboratory, Children s Mercy Hospital and Clinics, Kansas City, Missouri 64108, USA
    Am J Med Genet A 146:2346-54. 2008
    ..3 kb) imprinting center (IC) deletions, with no overlap in MFI values compared with normal loci. Using this diagnostic QMH assay, the precise deleted genomic interval could be ascertained in all PWS subjects examined in the present study...
  18. pmc Refining the 22q11.2 deletion breakpoints in DiGeorge syndrome by aCGH
    D C Bittel
    Children s Mercy Hospitals and Clinics, University of Missouri Kansas City School of Medicine, Kansas City, MO 64108, USA
    Cytogenet Genome Res 124:113-20. 2009
    ..2 deletion or DiGeorge syndrome...
  19. ncbi request reprint Brief report: non-random X chromosome inactivation in females with autism
    Z Talebizadeh
    Section of Medical Genetics and Molecular Medicine, Children s Mercy Hospitals and Clinics, University of Missouri Kansas City School of Medicine, MO 64108, USA
    J Autism Dev Disord 35:675-81. 2005
    ..X chromosome skewness has been reported in female carriers of other neurological disorders such as X-linked mental retardation, adrenoleukodystrophy and Rett syndrome...
  20. ncbi request reprint Metacarpophalangeal pattern profile analysis in Noonan syndrome
    M G Butler
    Children s Mercy Hospital, Kansas City, Missouri, USA
    Am J Med Genet 92:128-31. 2000
    ..The hand pattern variability index was outside of the normal range, indicating an abnormal MCPP with multivariate analysis. The MCPP analysis may be useful as a tool for diagnosis in screening subjects for Noonan syndrome...
  21. ncbi request reprint Comparison of X-chromosome inactivation patterns in multiple tissues from human females
    D C Bittel
    Section of Medical Genetics and Molecular Medicine, Children s Mercy Hospitals and Clinics and University of Missouri Kansas City School of Medicine, Kansas City, Missouri 64108, USA
    J Med Genet 45:309-13. 2008
    ..For accessible tissues to be informative for genetic analysis, a high degree of concordance of genetic findings among tissue types is required...
  22. ncbi request reprint Five new subjects with ring chromosome 22
    H A Ishmael
    The Children s Mercy Hospitals and Clinics and University of Missouri Kansas City School of Medicine, Kansas City, MO, USA
    Clin Genet 63:410-4. 2003
    ..Similarly, recessive alleles unmasked by the deletion could also contribute to the phenotype...
  23. pmc Global DNA promoter methylation in frontal cortex of alcoholics and controls
    A M Manzardo
    Department of Psychiatry and Behavioral Sciences, University of Kansas School of Medicine, Kansas City, KS 66160, USA
    Gene 498:5-12. 2012
    ..Our study provides insight into global epigenetic regulation in the human brain in relationship to controls and potentially novel targets for hypothesis generation and follow-up studies of alcoholism...
  24. doi request reprint Obese children show hyperactivation to food pictures in brain networks linked to motivation, reward and cognitive control
    A S Bruce
    Department of Preventive Medicine, Hoglund Brain Imaging Center, The University of Kansas Medical Center, Kansas City, KS, USA
    Int J Obes (Lond) 34:1494-500. 2010
    ..To investigate the neural mechanisms of food motivation in children and adolescents, and examine brain activation differences between healthy weight (HW) and obese participants...
  25. ncbi request reprint Methylation-specific multiplex ligation-dependent probe amplification analysis of subjects with chromosome 15 abnormalities
    Douglas C Bittel
    Children s Mercy Hospitals and Clinics, Section of Medical Genetics and Molecular Medicine, Kansas City, MO 64108, USA
    Genet Test 11:467-75. 2007
    ..MLPA is a relatively simple, cost-effective technique found to be useful and accurate for methylation status, copy number and analysis of genetic subtype in PWS and AS, as well as other chromosome 15 abnormalities...
  26. ncbi request reprint Whole genome microarray analysis of gene expression in Prader-Willi syndrome
    Douglas C Bittel
    Children s Mercy Hospitals and Clinics, University of Missouri Kansas City, School of Medicine, Kansas City, MO 64108, USA
    Am J Med Genet A 143:430-42. 2007
    ..Our analysis identified previously unappreciated changes in gene expression which may contribute to the clinical manifestations seen in PWS...
  27. pmc Neural mechanisms underlying hyperphagia in Prader-Willi syndrome
    Laura M Holsen
    Hoglund Brain Imaging Center, University of Kansas Medical Center, Kansas City, 66160, USA
    Obesity (Silver Spring) 14:1028-37. 2006
    ..We used functional magnetic resonance imaging to study the neural mechanisms underlying responses to visual food stimuli, before and after eating, in individuals with PWS and a healthy weight control (HWC) group...
  28. ncbi request reprint Microarray analysis of gene/transcript expression in Angelman syndrome: deletion versus UPD
    Douglas C Bittel
    Section of Medical Genetics and Molecular Medicine, Children s Mercy Hospitals and Clinics and University of Missouri at Kansas City School of Medicine, 2401 Gillham Road, Kansas City, MO 64108, USA
    Genomics 85:85-91. 2005
    ..Our results indicate that interconnected mechanisms can produce subtle and unexpected changes in gene expression that may help explain the phenotypic differences observed among the genetic subtypes of AS...
  29. ncbi request reprint Body composition and fatness patterns in Prader-Willi syndrome: comparison with simple obesity
    Mariana F Theodoro
    Section of Medical Genetics and Molecular Medicine, Children s Mercy Hospitals and Clinics, 2401 Gillham Road, Kansas City, MO 64108, USA
    Obesity (Silver Spring) 14:1685-90. 2006
    ..To characterize the body composition of Prader-Willi syndrome (PWS) subjects and compare with simple obesity...
  30. ncbi request reprint Ghrelin, peptide YY and their receptors: gene expression in brain from subjects with and without Prader-Willi syndrome
    Zohreh Talebizadeh
    Section of Medical Genetics and Molecular Medicine, Children s Mercy Hospitals and Clinics, University of Missouri Kansas City School of Medicine, Kansas City, MO 64108, USA
    Int J Mol Med 15:707-11. 2005
    ..Additional studies including quantitative gene expression measurements will be required to further evaluate the role of these genes in the eating disorder seen in PWS...
  31. ncbi request reprint Prader-Willi syndrome: clinical genetics, cytogenetics and molecular biology
    Douglas C Bittel
    Section of Medical Genetics and Molecular Medicine, Children s Mercy Hospitals and Clinics, and University of Missouri Kansas City School of Medicine, 2401 Gillham Rd, Kansas City, MO 64108, USA
    Expert Rev Mol Med 7:1-20. 2005
    ..Here, we describe the clinical presentation of PWS, review the current understanding of causative cytogenetic and molecular genetic mechanisms, and discuss future directions for research...
  32. pmc Maladaptive behaviors and risk factors among the genetic subtypes of Prader-Willi syndrome
    Sigan L Hartley
    Department of Psychology, University of Wyoming, Laramie, 82070, USA
    Am J Med Genet A 136:140-5. 2005
    ..The Reiss Screen cut-off scores were used to determine whether differences occurred between the subtypes at a clinically significant level. These findings offer insight into the health care needs of people with PWS...
  33. doi request reprint Autistic and dysmorphic features associated with a submicroscopic 2q33.3-q34 interstitial deletion detected by array comparative genomic hybridization
    Duane T Brandau
    Section of Medical Genetics and Molecular Medicine, Children s Mercy Hospitals and Clinics, University of Missouri Kansas City School of Medicine, Kansas City, Missouri 64108, USA
    Am J Med Genet A 146:521-4. 2008
  34. pmc A 9-year-old male with a duplication of chromosome 3p25.3p26.2: clinical report and gene expression analysis
    Douglas C Bittel
    Children s Mercy Hospitals and Clinics, University of Missouri Kansas City School of Medicine, Kansas City, Missouri 64108, USA
    Am J Med Genet A 140:573-9. 2006
    ..Our studies suggest increased expression of several genes in the 3p duplication region, including GHRL and PPARG, which may contribute to the phenotypic features in our 3p duplication subject...
  35. ncbi request reprint C-reactive protein levels in subjects with Prader-Willi syndrome and obesity
    Merlin G Butler
    Section of Medical Genetics and Molecular Medicine, Children s Mercy Hospitals and Clinics and University of Missouri Kansas City School of Medicine, Kansas City, MO 64108, USA
    Genet Med 8:243-8. 2006
    ..Therefore, we have measured the levels of C-reactive protein in a descriptive study of a cohort of Prader-Willi syndrome and comparison subjects...
  36. ncbi request reprint Whole genome microarray analysis of gene expression in subjects with fragile X syndrome
    Douglas C Bittel
    Children s Mercy Hospitals and Clinics and University of Missouri Kansas City School of Medicine, Kansas City, Missouri 64108, USA
    Genet Med 9:464-72. 2007
    ....
  37. doi request reprint Follicle stimulating and leutinizing hormones, estradiol and testosterone in Prader-Willi syndrome
    Duane T Brandau
    Section of Medical Genetics and Molecular Medicine, Children s Mercy Hospitals and Clinics, University of Missouri Kansas City School of Medicine, Kansas City, Missouri 64108, USA
    Am J Med Genet A 146:665-9. 2008
  38. doi request reprint Expanding the phenotype of SPONASTRIME dysplasia to include short dental roots, hypogammaglobulinemia, and cataracts
    Karen W Gripp
    Division of Medical Genetics, A I duPont Hospital for Children, Wilmington, Delaware 19803, USA
    Am J Med Genet A 146:468-73. 2008
    ..We follow two previously reported patients with SD [Patients 3, 4 in Langer et al. 1996; Am J Med Genet 63: 20-27]. Since the original publication, additional findings were identified in these patients...
  39. pmc Gastric rupture and necrosis in Prader-Willi syndrome
    David A Stevenson
    Department of Pediatrics, Division of Medical Genetics, University of Utah, Salt Lake City, UT 84132, USA
    J Pediatr Gastroenterol Nutr 45:272-4. 2007
    ..The physician should consider an emergent evaluation for gastric rupture and necrosis in individuals with PWS who present with vomiting and abdominal pain...
  40. ncbi request reprint Neuroimaging findings in macrocephaly-capillary malformation: a longitudinal study of 17 patients
    Robert L Conway
    Cedars Sinai Medical Center, Los Angeles, California, USA
    Am J Med Genet A 143:2981-3008. 2007
    ..One patient was found to have a frontal perifalcine mass resembling a meningioma at age 5 years. This is the second apparent occurrence of this specific tumor in M-CM...
  41. ncbi request reprint Clonality studies in sacral chordoma
    Lance Klingler
    Division of Orthopedics, School of Medicine, Southern Illinois University, Springfield, IL 62794 9679, USA
    Cancer Genet Cytogenet 171:68-71. 2006
    ..Most solid tumors and skeletal neoplasms are polyclonal in nature. Our study indicates that chordoma is polyclonal in its pattern of proliferation...
  42. ncbi request reprint Oculoauriculofrontonasal syndrome (OAFNS) in a nine-month-old male
    Holly A Ishmael
    Children s Mercy Hospital and Clinic, Kansas City, Missouri 64108, USA
    Am J Med Genet 107:169-73. 2002
    ..This constellation of anomalies is consistent with the diagnosis of oculoauriculofrontonasal syndrome (OAFNS) which appears to be a distinct condition from either OAVS or FND but with overlapping features...
  43. ncbi request reprint Marshall-Smith syndrome: Follow-up report of a four and a half year old male
    Merlin G Butler
    Am J Med Genet A 126:329-30. 2004
  44. ncbi request reprint Do known mutations in neuroligin genes (NLGN3 and NLGN4) cause autism?
    Zohreh Talebizadeh
    J Autism Dev Disord 34:735-6. 2004
  45. ncbi request reprint Deletion of and novel missense mutation in POU3F4 in 2 families segregating X-linked nonsyndromic deafness
    Abram P Vore
    Molecular Otolaryngology Research Laboratories, Department of Otolaryngology Head and Neck Surgery, The University of Iowa, Iowa City 52242, USA
    Arch Otolaryngol Head Neck Surg 131:1057-63. 2005
    ..To analyze the physical manifestations and genetic features of 2 families segregating X-linked deafness, which is most commonly reported to be caused by mutations of the POU domain gene POU3F4 at the DFN3 locus...
  46. ncbi request reprint Cytogenetic heteromorphisms: survey results and reporting practices of giemsa-band regions that we have pondered for years
    Arthur R Brothman
    Department of Pediatrics and Human Genetics, University of Utah School of Medicine, Salt Lake City, USA
    Arch Pathol Lab Med 130:947-9. 2006
    ..Cytogenetic heteromorphisms (normal variants) pose diagnostic dilemmas. Common Giemsa-band heteromorphisms are not described in the literature, although Giemsa-banding is the method most frequently used in cytogenetic laboratories...
  47. ncbi request reprint Newborn with anophthalmia and features of Fryns syndrome
    Diane M Pierson
    Department of Pathology, Truman Medical Center, Kansas City, MO, USA
    Pediatr Dev Pathol 5:592-6. 2002
    ..Anophthalmia, to our knowledge, has not been reported previously in Fryns syndrome; however, eye findings are common, particularly microphthalmia and cloudy cornea...
  48. ncbi request reprint X chromosome gene expression in human tissues: male and female comparisons
    Zohreh Talebizadeh
    Section of Medical Genetics and Molecular Medicine, Children s Mercy Hospitals and Clinics, University of Missouri at Kansas City School of Medicine, Kansas City, MO 64108, USA
    Genomics 88:675-81. 2006
    ..This study indicates that factors other than the X-inactivation process may impact on the expression of X-linked genes resulting in an overall similar gender expression for both X-linked and autosomal genes...
  49. ncbi request reprint Expression of 4 genes between chromosome 15 breakpoints 1 and 2 and behavioral outcomes in Prader-Willi syndrome
    Douglas C Bittel
    Children s Mercy Hospitals and Clinics and University of Missouri Kansas City School of Medicine, Kansas City, MO 64108, USA
    Pediatrics 118:e1276-83. 2006
    ..Additional research is needed to identify the function of these genes and their interaction with gene networks to clarify the potential role they play in central nervous system development and function...
  50. pmc Deaths due to choking in Prader-Willi syndrome
    David A Stevenson
    Department of Pediatrics, Division of Medical Genetics, University of Utah, Salt Lake City, Utah 84132, USA
    Am J Med Genet A 143:484-7. 2007
    ....
  51. ncbi request reprint Whole genome microarray analysis of gene expression in an imprinting center deletion mouse model of Prader-Willi syndrome
    Douglas C Bittel
    Children s Mercy Hospitals and Clinics and University of Missouri Kansas City, School of Medicine, Kansas City, Missouri 54108, USA
    Am J Med Genet A 143:422-9. 2007
    ..These results, along with other recent reports, suggest that the cumulative effect of modest changes in expression of many genes, especially genes involved in energy metabolism, contribute to the failure to thrive of infants with PWS...
  52. ncbi request reprint Drowning as a cause of death in Angelman syndrome
    Holly A Ishmael
    Children s Mercy Hospitals, University of Missouri Kansas City School of Medicine, MO 64108, USA
    Am J Ment Retard 107:69-70. 2002
    ..We wish to alert careproviders that this fascination with water and water-related activities may contribute to death and that these individuals should be closely supervised when in the presence of water...