Rachel P Berger

Summary

Affiliation: Children's Hospital of Pittsburgh
Country: USA

Publications

  1. pmc Common data elements for pediatric traumatic brain injury: recommendations from the biospecimens and biomarkers workgroup
    Rachel P Berger
    Children s Hospital of Pittsburgh of UPMC, Safar Center for Resuscitation Research, University of Pittsburgh, Pittsburgh, Pennsylvania 15224, USA
    J Neurotrauma 29:672-7. 2012
  2. doi request reprint Serum biomarkers of brain injury to classify outcome after pediatric cardiac arrest*
    Ericka L Fink
    1Department of Critical Care Medicine, Children s Hospital of Pittsburgh of UPMC, Pittsburgh, PA 2Department of Pediatrics, Children s Hospital of Pittsburgh of UPMC, Pittsburgh, PA 3Department of Critical Care Medicine, University of Pittsburgh Medical Center, Pittsburgh, PA 4Statistical Analysis and Measurement Consultants, Inc, Lanexa, VA 5Department of Radiology, Children s Hospital of Pittsburgh of UPMC, Pittsburgh, PA 6Department of Emergency Medicine, University of Pittsburgh Medical Center, Pittsburgh, PA
    Crit Care Med 42:664-74. 2014
  3. pmc Risk factors for mortality in children with abusive head trauma
    Steven L Shein
    Department of Critical Care Medicine, Children s Hospital of Pittsburgh of UPMC, Pittsburgh, PA 15260, USA
    J Pediatr 161:716-722.e1. 2012
  4. doi request reprint Biomarkers of primary and evolving damage in traumatic and ischemic brain injury: diagnosis, prognosis, probing mechanisms, and therapeutic decision making
    Patrick M Kochanek
    Safar Center for Resuscitation Research, Department of Critical Care Medicine, University of Pittsburgh School of Medicine, Pittsburgh, Pennsylvania 15260, USA
    Curr Opin Crit Care 14:135-41. 2008
  5. pmc Validity of a pediatric version of the Glasgow Outcome Scale-Extended
    Sue R Beers
    Department of Psychiatry, University of Pittsburgh School of Medicine, Pittsburgh, Pennsylvania 15213, USA
    J Neurotrauma 29:1126-39. 2012
  6. pmc A gel-based proteomic comparison of human cerebrospinal fluid between inflicted and non-inflicted pediatric traumatic brain injury
    Wei Min Gao
    Department of Critical Care Medicine, University of Pittsburgh School of Medicine, Pittsburgh, PA 15260, USA
    J Neurotrauma 24:43-53. 2007
  7. ncbi request reprint Multiplex assessment of cytokine and chemokine levels in cerebrospinal fluid following severe pediatric traumatic brain injury: effects of moderate hypothermia
    Sandra D W Buttram
    Safar Center for Resuscitation Research, University of Pittsburgh School of Medicine, Pittsburgh, Pennsylvania 15260, USA
    J Neurotrauma 24:1707-17. 2007
  8. pmc Quantification of poly(ADP-ribose)-modified proteins in cerebrospinal fluid from infants and children after traumatic brain injury
    Ericka L Fink
    Department of Critical Care Medicine, Safar Center for Resuscitation Research and Brain Trauma Research Center, University of Pittsburgh School of Medicine, Pittsburgh, Pennsylvania, USA
    J Cereb Blood Flow Metab 28:1523-9. 2008
  9. pmc Serum concentrations of ubiquitin C-terminal hydrolase-L1 and αII-spectrin breakdown product 145 kDa correlate with outcome after pediatric TBI
    Rachel P Berger
    Children s Hospital of Pittsburgh of University of Pittsburgh Medical Center UPMC, Safar Center for Resuscitation Research, Pittsburgh, Pennsylvania 15224, USA
    J Neurotrauma 29:162-7. 2012
  10. pmc S100b as a prognostic biomarker in outcome prediction for patients with severe traumatic brain injury
    Akash Goyal
    Department of Physical Medicine and Rehabilitation, University of Pittsburgh, Pittsburgh, Pennsylvania 15213, USA
    J Neurotrauma 30:946-57. 2013

Collaborators

Detail Information

Publications23

  1. pmc Common data elements for pediatric traumatic brain injury: recommendations from the biospecimens and biomarkers workgroup
    Rachel P Berger
    Children s Hospital of Pittsburgh of UPMC, Safar Center for Resuscitation Research, University of Pittsburgh, Pittsburgh, Pennsylvania 15224, USA
    J Neurotrauma 29:672-7. 2012
    ....
  2. doi request reprint Serum biomarkers of brain injury to classify outcome after pediatric cardiac arrest*
    Ericka L Fink
    1Department of Critical Care Medicine, Children s Hospital of Pittsburgh of UPMC, Pittsburgh, PA 2Department of Pediatrics, Children s Hospital of Pittsburgh of UPMC, Pittsburgh, PA 3Department of Critical Care Medicine, University of Pittsburgh Medical Center, Pittsburgh, PA 4Statistical Analysis and Measurement Consultants, Inc, Lanexa, VA 5Department of Radiology, Children s Hospital of Pittsburgh of UPMC, Pittsburgh, PA 6Department of Emergency Medicine, University of Pittsburgh Medical Center, Pittsburgh, PA
    Crit Care Med 42:664-74. 2014
    ..We hypothesized that serum biomarkers can be used to classify outcome from pediatric cardiac arrest...
  3. pmc Risk factors for mortality in children with abusive head trauma
    Steven L Shein
    Department of Critical Care Medicine, Children s Hospital of Pittsburgh of UPMC, Pittsburgh, PA 15260, USA
    J Pediatr 161:716-722.e1. 2012
    ..We sought to identify risk factors for mortality in a large clinical cohort of children with abusive head trauma...
  4. doi request reprint Biomarkers of primary and evolving damage in traumatic and ischemic brain injury: diagnosis, prognosis, probing mechanisms, and therapeutic decision making
    Patrick M Kochanek
    Safar Center for Resuscitation Research, Department of Critical Care Medicine, University of Pittsburgh School of Medicine, Pittsburgh, Pennsylvania 15260, USA
    Curr Opin Crit Care 14:135-41. 2008
    ..Novel proteomic, multiplex, and lipidomic methods are also being applied...
  5. pmc Validity of a pediatric version of the Glasgow Outcome Scale-Extended
    Sue R Beers
    Department of Psychiatry, University of Pittsburgh School of Medicine, Pittsburgh, Pennsylvania 15213, USA
    J Neurotrauma 29:1126-39. 2012
    ..This pediatric revision provides a valid outcome measure in infants, toddlers, children, and adolescents through age 16. Findings support using the GOS-E Peds as the primary outcome variable in pediatric clinical trials...
  6. pmc A gel-based proteomic comparison of human cerebrospinal fluid between inflicted and non-inflicted pediatric traumatic brain injury
    Wei Min Gao
    Department of Critical Care Medicine, University of Pittsburgh School of Medicine, Pittsburgh, PA 15260, USA
    J Neurotrauma 24:43-53. 2007
    ..These initial results with conventional gel-based proteomics show new protein changes that may ultimately help to understand pathophysiological differences between iTBI and nTBI...
  7. ncbi request reprint Multiplex assessment of cytokine and chemokine levels in cerebrospinal fluid following severe pediatric traumatic brain injury: effects of moderate hypothermia
    Sandra D W Buttram
    Safar Center for Resuscitation Research, University of Pittsburgh School of Medicine, Pittsburgh, Pennsylvania 15260, USA
    J Neurotrauma 24:1707-17. 2007
    ..Moderate therapeutic hypothermia did not attenuate the increase in CSF cytokine levels in children after TBI...
  8. pmc Quantification of poly(ADP-ribose)-modified proteins in cerebrospinal fluid from infants and children after traumatic brain injury
    Ericka L Fink
    Department of Critical Care Medicine, Safar Center for Resuscitation Research and Brain Trauma Research Center, University of Pittsburgh School of Medicine, Pittsburgh, Pennsylvania, USA
    J Cereb Blood Flow Metab 28:1523-9. 2008
    ..As PAR-modified protein concentration correlated with age and male sex, developmental and sex-dependent roles for PARP after TBI are implicated...
  9. pmc Serum concentrations of ubiquitin C-terminal hydrolase-L1 and αII-spectrin breakdown product 145 kDa correlate with outcome after pediatric TBI
    Rachel P Berger
    Children s Hospital of Pittsburgh of University of Pittsburgh Medical Center UPMC, Safar Center for Resuscitation Research, Pittsburgh, Pennsylvania 15224, USA
    J Neurotrauma 29:162-7. 2012
    ..These results suggest that these two markers may be useful in assessing outcome after moderate and severe pediatric TBI...
  10. pmc S100b as a prognostic biomarker in outcome prediction for patients with severe traumatic brain injury
    Akash Goyal
    Department of Physical Medicine and Rehabilitation, University of Pittsburgh, Pittsburgh, Pennsylvania 15213, USA
    J Neurotrauma 30:946-57. 2013
    ..022) and older subjects (p = 0.004). Multivariate logistic regression confirmed CSF S100b profiles in predicting GOS and DRS and showed mean and peak serum S100b as acute mortality predictors after sTBI...
  11. pmc The potential for bio-mediators and biomarkers in pediatric traumatic brain injury and neurocritical care
    Patrick M Kochanek
    Safar Center for Resuscitation Research, Department of Critical Care Medicine, University of Pittsburgh School of Medicine Pittsburgh, PA, USA
    Front Neurol 4:40. 2013
    ..The potential scope of the utility of biomarkers in pediatric neurocritical care is thus also discussed...
  12. doi request reprint Relationship of intracranial pressure and cerebral perfusion pressure with outcome in young children after severe traumatic brain injury
    Amit Mehta
    Department of Critical Care Medicine, University of Pittsburgh, Pittsburgh, PA 15260, USA
    Dev Neurosci 32:413-9. 2010
    ..A prospective study is needed to fully determine what goals should be targeted for this vulnerable population...
  13. ncbi request reprint Neurocognitive outcome and serum biomarkers in inflicted versus non-inflicted traumatic brain injury in young children
    Sue R Beers
    Department of Psychiatry, University of Pittsburgh School of Medicine, Pittsburgh, PA 15260, USA
    J Neurotrauma 24:97-105. 2007
    ..Outcome may be due to the mechanism of iTBI, cumulative effects of unreported TBI, and/or other unidentified risk factors...
  14. pmc Susceptibility weighted imaging depicts retinal hemorrhages in abusive head trauma
    Giulio Zuccoli
    Department of Pediatric Radiology, Children s Hospital of Pittsburgh of UPMC, 4401 Penn Avenue, Pittsburgh, PA 15224, USA
    Neuroradiology 55:889-93. 2013
    ..This study aims to evaluate the capability of magnetic resonance imaging (MRI) susceptibility weighted images (SWI) in depicting retinal hemorrhages (RH) in abusive head trauma (AHT) compared to the gold standard dilated fundus exam (DFE)...
  15. ncbi request reprint Multiplex assessment of serum biomarker concentrations in well-appearing children with inflicted traumatic brain injury
    Rachel P Berger
    Department of Pediatrics, University of Pittsburgh, Pittsburgh, Pennsylvania 15213, USA
    Pediatr Res 65:97-102. 2009
    ..The results suggest significant changes in the serum biomarker profile after mild ITBI. Future research is needed to determine whether these biomarkers can screen for brain injury in infants with nonspecific symptoms...
  16. doi request reprint Increased serum creatine phosphokinase in a child with bruising due to physical abuse
    Stephanie Sussman
    Department of Pediatrics, Children s Hospital of Pittsburgh, University of Pittsburgh Medical Center, Pittsburgh, PA, USA
    Pediatr Emerg Care 28:1366-8. 2012
    ..We recommend that physicians consider measuring serum CPK in children with bruising due to physical abuse...
  17. doi request reprint Translating biomarkers research to clinical care: applications and issues for rehabilomics
    Rachel P Berger
    Critical Care Medicine, Neurological Surgery and Pediatrics, Children s Hospital of Pittsburgh of UPMC, Safar Center for Resuscitation Research, 4401 Penn Ave, Pittsburgh, PA 15224, USA
    PM R 3:S31-8. 2011
    ..Introduction of the concept of rehabilomics and implications of biomarker use for the physical medicine and rehabilitation physician also are discussed...
  18. doi request reprint Assessing the use of follow-up skeletal surveys in children with suspected physical abuse
    Ranjodh Singh
    Department of Pediatrics, Children s Hospital of Pittsburgh, University of Pittsburgh Medical Center, Pittsburgh, Pennsylvania, USA
    J Trauma Acute Care Surg 73:972-6. 2012
    ....
  19. pmc The utility of near infrared spectroscopy in detecting intracranial hemorrhage in children
    Rosanne Salonia
    Department of Critical Care Medicine, Children s Hospital of Pittsburgh of the UPMC, University of Pittsburgh School of Medicine, Pittsburgh, Pennsylvania 15224, USA
    J Neurotrauma 29:1047-53. 2012
    ..8 and 1.0, respectively. In conclusion, NIRS correctly identified all cases of ICH in this pilot study. Our preliminary results suggest that NIRS may be beneficial in the evaluation of a child with possible ICH...
  20. doi request reprint Retinal hemorrhages in low-risk children evaluated for physical abuse
    Simiao Li
    Department of Pediatrics, Child Advocacy Center, Children s Hospital of Pittsburgh of University of Pittsburgh Medical Center, 4401 Penn Avenue, Pittsburgh, PA 15224, USA
    Arch Pediatr Adolesc Med 165:913-7. 2011
    ....
  21. doi request reprint Abusive head trauma during a time of increased unemployment: a multicenter analysis
    Rachel P Berger
    Department of Pediatrics, Children s Hospital of Pittsburgh of UPMC, Pittsburgh, Pennsylvania 15224, USA
    Pediatrics 128:637-43. 2011
    ..To evaluate the rate of abusive head trauma (AHT) in 3 regions of the United States before and during an economic recession and assess whether there is a relationship between the rate of AHT and county-level unemployment rates...
  22. ncbi request reprint The other children: a survey of child abuse physicians on the medical evaluation of children living with a physically abused child
    Kristine A Campbell
    General Academic Pediatrics, Children s Hospital of Pittsburgh, Pittsburgh, PA, USA
    Arch Pediatr Adolesc Med 160:1241-6. 2006
    ..To explore the practice and attitudes of child abuse physicians regarding the evaluation of "contact children" identified in the home of a physically abused index child...
  23. ncbi request reprint Cytochrome c, a biomarker of apoptosis, is increased in cerebrospinal fluid from infants with inflicted brain injury from child abuse
    Margaret A Satchell
    Department of Critical Care Medicine, The Safar Center for Resuscitation Research, University of Pittsburgh School of Medicine, Pittsburgh, Pennsylvania, USA
    J Cereb Blood Flow Metab 25:919-27. 2005
    ..The degree of apoptosis after TBI also appears to be gender-dependent. Development of strategies targeting apoptosis after TBI, particularly in victims of child abuse and in girls, appears justified...