Michael J Bell
Affiliation: Children's National Medical Center
- Effects of intrauterine inflammation on developing rat brainMichael J Bell
Stroke Branch, National Institute of Neurological Diseases and Stroke, National Institute of Health, Bethesda, Maryland, USA
J Neurosci Res 70:570-9. 2002..Our model of intrauterine inflammation causes increased TUNEL and TNF-alpha staining early after injury, suggesting increased apoptotic cell death, possibly by cytokine-related mechanisms...
- Determining the fetal inflammatory response in an experimental model of intrauterine inflammation in ratsMichael J Bell
Center for Neuroscience Research, Children s Research Institute, Children s National Medical Center, Washington University School of Medicine, Washington, D C, 20010 USA
Pediatr Res 56:541-6. 2004..By studying placental and brain cytokine responses in models such as ours, the mechanisms responsible for the damage to developing white matter can be determined...
- Correlation of cerebral Near-infrared spectroscopy (cNIRS) and neurological markers in critically ill childrenAnjali Subbaswamy
Division of Critical Care Medicine, Children s National Medical Center, Washington, DC 20010, USA
Neurocrit Care 10:129-35. 2009..To correlate regional brain saturations (RSO(2)) measured by cerebral Near-infrared spectroscopy (cNIRS) with serological markers indicative of neurological injury (neuron-specific enolase (NSE) and S100beta)...
- Inadvertent hyponatremia leading to acute cerebral edema and early evidence of herniationJessica Carpenter
Department of Neurology, Children s Research Institute, Children s National Medical Center, Washington, DC, USA
Neurocrit Care 6:195-9. 2007..Severe hyponatremia has long been known to be detrimental, but objective evidence for the harm of mild hyponatremia as a secondary injury has been scarce...
- Cerebral hemorrhage and vasospasm in a child with congenital heart diseaseJessica Carpenter
Division of Neurology, Children s National Medical Center, 111 Michigan Avenue, NW, Washington, DC 20010, USA
Neurocrit Care 8:276-9. 2008..Children with structural congenital heart disease are particularly at risk for both thrombotic and embolic events but not to isolated hemorrhages...
- Development of a pediatric neurocritical care serviceMichael J Bell
Division of Critical Care Medicine, Children s National Medical Center, Washington, DC, 20010, USA
Neurocrit Care 10:4-10. 2009..To describe the development of a Pediatric Neurocritical Care (PNCCM) service; define the patient population that requires the service and describe important outcome parameters...
- Neurological injury markers in children with septic shockAngela A Hsu
Division of Critical Care Medicine, Children s Research Institute, Children s National Medical Center, Washington, DC, USA
Pediatr Crit Care Med 9:245-51. 2008..To determine whether known serum markers of neurologic injury are increased in children with septic shock...
- Caspase activation in fetal rat brain following experimental intrauterine inflammationAditi Sharangpani
Division of Critical Care Medicine and Center for Neuroscience Research, Children s Research Institute, Children s National Medical Center, George Washington University School of Medicine, Washington, DC 20010, USA
Brain Res 1200:138-45. 2008..Understanding the mechanisms of cell death in models of intrauterine inflammation may affect development of future strategies to mitigate these injuries in children...
- Incidence of postoperative hyponatremia and complications in critically-ill children treated with hypotonic and normotonic solutionsAlicia K Au
Department of Pediatrics, Children s National Medical Center, Washington, DC, USA
J Pediatr 152:33-8. 2008..To determine the incidence and clinical consequences of postoperative hyponatremia in children...
- Interleukin-6, interleukin-8, and a rapid and sensitive assay for calcitonin precursors for the determination of bacterial sepsis in febrile neutropenic childrenGlenn R Stryjewski
Department of Pediatrics and Critical Care Medicine, Children s National Medical Center, Washington, DC, USA
Pediatr Crit Care Med 6:129-35. 2005....
- Increases in serum levels of troponin I are associated with cardiac dysfunction and disease severity in pediatric patients with septic shockKimberly E Fenton
State University of New York at Stony Brook, Stony Brook, NY, USA
Pediatr Crit Care Med 5:533-8. 2004..Troponin I is a biochemical marker of myocardial cell injury and death. We hypothesized that troponin I is increased in pediatric patients with septic shock and correlates with cardiac dysfunction and disease severity...
- Hypothermia therapy after traumatic brain injury in childrenPatrick M Kochanek
N Engl J Med 359:1179; author reply 1180. 2008
- Effects of inflammation on developing gliaMichael Bell; Fiscal Year: 2007..Mentorship in neuroscience as well as the resources of the Mental Retardation and Developmental Disabilities Research Center will support these well-defined training objectives. ..