U S Alon

Summary

Affiliation: Children's Mercy Hospital
Country: USA

Publications

  1. ncbi request reprint Preservation of bone mass in pediatric dialysis and transplant patients
    U S Alon
    Section of Pediatric Nephrology and Bone and Mineral Disorders Clinic, The Children s Mercy Hospital, University of Missouri at Kansas City, Kansas City, MO 64108, USA
    Adv Ren Replace Ther 8:191-205. 2001
  2. pmc Phosphate homeostasis and its role in bone health
    Maria Goretti M G Penido
    Pediatric Nephrology Unit, Clinics Hospital, School of Medicine, Federal University of Minas Gerais, Belo Horizonte, Brazil
    Pediatr Nephrol 27:2039-48. 2012
  3. ncbi request reprint Diseases and clinical applications of the calcium sensing receptor
    Uri S Alon
    Section of Pediatric Nephrology, Children s Mercy Hospital, 2401 Gillham Road, Kansas City, MO 64108, USA
    Pediatr Endocrinol Rev 5:482-8. 2007
  4. pmc Medical treatment of pediatric urolithiasis
    Uri S Alon
    Bone and Mineral Disorders Clinic, Children s Mercy Hospital and Clinics, University of Missouri at Kansas City, 64108, USA
    Pediatr Nephrol 24:2129-35. 2009
  5. ncbi request reprint Hypertension in hypophosphatemic rickets--role of secondary hyperparathyroidism
    Uri S Alon
    Section of Pediatric Nephrology, Children s Mercy Hospital, University of Missouri at Kansas City, 2401 Gillham Road, Kansas City, MO 64108, USA
    Pediatr Nephrol 18:155-8. 2003
  6. ncbi request reprint Beneficial effect of cinacalcet in a child with familial hypocalciuric hypercalcemia
    Uri S Alon
    Section of Pediatric Nephrology, Bone and Mineral Disorders Clinic, Children s Mercy Hospitals and Clinics, University of Missouri at Kansas City, 2401 Gillham Road, Kansas City, MI 64108, USA
    Pediatr Nephrol 25:1747-50. 2010
  7. ncbi request reprint Evaluation and treatment of pediatric idiopathic urolithiasis-revisited
    Uri S Alon
    Section of Pediatric Nephrology, Children s Mercy Hospital, University of Missouri at Kansas City, Kansas City, Missouri 64108, USA
    Pediatr Nephrol 19:516-20. 2004
  8. doi request reprint Clinical practice. Fibroblast growth factor (FGF)23: a new hormone
    Uri S Alon
    Bone and Mineral Disorders Clinic, Section of Pediatric Nephrology, Children s Mercy Hospitals and Clinics, University of Missouri at Kansas City School of Medicine, 2401 Gillham Road, Kansas City, MO 64108, USA
    Eur J Pediatr 170:545-54. 2011
  9. pmc Calcimimetics as an adjuvant treatment for familial hypophosphatemic rickets
    Uri S Alon
    Pediatric Nephrology, Bone and Mineral Disorders Clinic, Children s Mercy Hospital, University of Missouri, Kansas City, MO 64108, USA
    Clin J Am Soc Nephrol 3:658-64. 2008
  10. ncbi request reprint Idiopathic hypercalciuria of childhood: 4- to 11-year outcome
    U S Alon
    Section of Pediatric Nephrology, The Children s Mercy Hospital, University of Missouri at Kansas City, 64108, USA
    Pediatr Nephrol 14:1011-5. 2000

Research Grants

Collaborators

Detail Information

Publications47

  1. ncbi request reprint Preservation of bone mass in pediatric dialysis and transplant patients
    U S Alon
    Section of Pediatric Nephrology and Bone and Mineral Disorders Clinic, The Children s Mercy Hospital, University of Missouri at Kansas City, Kansas City, MO 64108, USA
    Adv Ren Replace Ther 8:191-205. 2001
    ..Bone health and the child's somatic growth at ESRD or after kidney transplantation are closely related, and therapy should be aimed at achieving optimal results for both...
  2. pmc Phosphate homeostasis and its role in bone health
    Maria Goretti M G Penido
    Pediatric Nephrology Unit, Clinics Hospital, School of Medicine, Federal University of Minas Gerais, Belo Horizonte, Brazil
    Pediatr Nephrol 27:2039-48. 2012
    ..In the rest of the skeleton, hypophosphatemia will result in osteomalacia due to an insufficient formation of hydroxyapatite. This review will address phosphate metabolism and its role in bone health...
  3. ncbi request reprint Diseases and clinical applications of the calcium sensing receptor
    Uri S Alon
    Section of Pediatric Nephrology, Children s Mercy Hospital, 2401 Gillham Road, Kansas City, MO 64108, USA
    Pediatr Endocrinol Rev 5:482-8. 2007
    ..This review article will address our current understanding of the physiology, pathophysiology, diseases and clinical applications of the CaSR...
  4. pmc Medical treatment of pediatric urolithiasis
    Uri S Alon
    Bone and Mineral Disorders Clinic, Children s Mercy Hospital and Clinics, University of Missouri at Kansas City, 64108, USA
    Pediatr Nephrol 24:2129-35. 2009
    ..This review discusses the current options of medical treatment of pediatric urolithiasis...
  5. ncbi request reprint Hypertension in hypophosphatemic rickets--role of secondary hyperparathyroidism
    Uri S Alon
    Section of Pediatric Nephrology, Children s Mercy Hospital, University of Missouri at Kansas City, 2401 Gillham Road, Kansas City, MO 64108, USA
    Pediatr Nephrol 18:155-8. 2003
    ..Emphasis should therefore be placed on prevention of the development of HPTD as a complication of XLH treatment, and close monitoring for hypertension in those who do develop HPTD...
  6. ncbi request reprint Beneficial effect of cinacalcet in a child with familial hypocalciuric hypercalcemia
    Uri S Alon
    Section of Pediatric Nephrology, Bone and Mineral Disorders Clinic, Children s Mercy Hospitals and Clinics, University of Missouri at Kansas City, 2401 Gillham Road, Kansas City, MI 64108, USA
    Pediatr Nephrol 25:1747-50. 2010
    ..Over the 12-month treatment period no complications were noted. We conclude that cinacalcet may be considered a new, and currently the only, tool in treating children with symptomatic FHH...
  7. ncbi request reprint Evaluation and treatment of pediatric idiopathic urolithiasis-revisited
    Uri S Alon
    Section of Pediatric Nephrology, Children s Mercy Hospital, University of Missouri at Kansas City, Kansas City, Missouri 64108, USA
    Pediatr Nephrol 19:516-20. 2004
    ..Children rarely comply with the recommendation of high fluid intake...
  8. doi request reprint Clinical practice. Fibroblast growth factor (FGF)23: a new hormone
    Uri S Alon
    Bone and Mineral Disorders Clinic, Section of Pediatric Nephrology, Children s Mercy Hospitals and Clinics, University of Missouri at Kansas City School of Medicine, 2401 Gillham Road, Kansas City, MO 64108, USA
    Eur J Pediatr 170:545-54. 2011
    ..This review addresses the physiology and pathophysiology of FGF23 and its clinical applications...
  9. pmc Calcimimetics as an adjuvant treatment for familial hypophosphatemic rickets
    Uri S Alon
    Pediatric Nephrology, Bone and Mineral Disorders Clinic, Children s Mercy Hospital, University of Missouri, Kansas City, MO 64108, USA
    Clin J Am Soc Nephrol 3:658-64. 2008
    ....
  10. ncbi request reprint Idiopathic hypercalciuria of childhood: 4- to 11-year outcome
    U S Alon
    Section of Pediatric Nephrology, The Children s Mercy Hospital, University of Missouri at Kansas City, 64108, USA
    Pediatr Nephrol 14:1011-5. 2000
    ..If they are at risk then long-term compliance with a low-Na/high-K diet might be beneficial, as it can normalize calciuria in the majority of these children...
  11. ncbi request reprint Synaptopodin expression in idiopathic nephrotic syndrome of childhood
    T Srivastava
    Section of Nephrology and Department of Pathology, The Children's Mercy Hospital, University of Missouri at Kansas City, Kansas City, Missouri, USA
    Kidney Int 59:118-25. 2001
    ..CONCLUSION: We conclude that measurement of synaptopodin has the potential to be used as a marker to study the alteration in podocyte cell and response to therapy in INS...
  12. ncbi request reprint C1q nephropathy presenting as rapidly progressive crescentic glomerulonephritis
    T Srivastava
    Section of Nephrology, The Children s Mercy Hospital, University of Missouri at Kansas City, 64108, USA
    Pediatr Nephrol 14:976-9. 2000
    ..C1q nephropathy should be added to the differential diagnosis of glomerulonephritis in young children and in the patient with crescentic glomerulonephritis...
  13. ncbi request reprint Effect of thiazide on established furosemide-induced nephrocalcinosis in the young rat
    S Knoll
    Section of Pediatric Nephrology, Children s Mercy Hospital, University of Missouri at Kansas City 64108, USA
    Pediatr Nephrol 14:32-5. 2000
    ..Urine Ca excretion was significantly lower in groups F and G than groups D and E. We conclude that once established, NC caused by furosemide is not affected by CTZ therapy in spite of the anticalciuric property of the latter...
  14. ncbi request reprint Effect of the calcimimetic NPS R-467 on furosemide-induced nephrocalcinosis in the young rat
    Anirut Pattaragarn
    Section of Pediatric Nephrology, Children s Mercy Hospital, University of Missouri Kansas City, Kansas City, Missouri 64108, USA
    Kidney Int 65:1684-9. 2004
    ..Calcimimetic agents such as NPS R-467 are potent and selective agonists at the calcium-sensing receptor in parathyroid glands and inhibit PTH secretion...
  15. ncbi request reprint Cell-cycle regulatory proteins in podocyte cell in idiopathic nephrotic syndrome of childhood
    Tarak Srivastava
    Section of Nephrology and Department of Pathology, The Children s Mercy Hospital, University of Missouri at Kansas City, 64108, USA
    Kidney Int 63:1374-81. 2003
    ..We investigated for alterations in the expression of cyclin kinase inhibitors, p27, p57, p21, and cyclins D and A in the podocyte cell of children with INS...
  16. ncbi request reprint Essentials of laboratory medicine for the nephrology clinician
    Tarak Srivastava
    Section of Nephrology, Children s Mercy Hospital and University of Missouri, 2401Gillham Road, Kansas City, MO 64108, USA
    Pediatr Nephrol 22:170-82. 2007
    ..An understanding of the considerations and limitations in laboratory medicine will be helpful to the pediatric nephrologist when ordering and interpreting biochemical tests...
  17. ncbi request reprint Impact of standardization of creatinine methodology on the assessment of glomerular filtration rate in children
    Tarak Srivastava
    Section of Nephrology, University of Missouri at Kansas City, MO 64108, USA
    Pediatr Res 65:113-6. 2009
    ....
  18. ncbi request reprint Urine calcium/citrate ratio in children with hypercalciuric stones
    Tarak Srivastava
    Bone and Mineral Disorder Clinic, University of Missouri at Kansas City, 2401 Gillham Road, Kansas City, MO 64108, USA
    Pediatr Res 66:85-90. 2009
    ..Whether intervention in hypercalciuric children to lower urine calcium/citrate <0.326 will provide protection against stone formation needs to be studied...
  19. doi request reprint Parathyroid-hormone-related protein-mediated hypercalcemia in benign congenital mesoblastic nephroma
    Tarak Srivastava
    University of Missouri, Kansas City, MO 64108, USA
    Pediatr Nephrol 26:799-803. 2011
    ....
  20. doi request reprint Atorvastatin may have no effect on acute phase reaction in children after intravenous bisphosphonate infusion
    Tarak Srivastava
    Bone and Mineral Disorder Clinic, Section of Nephrology, Children s Mercy Hospital and University of Missouri, Kansas City, Missouri 64108, USA
    J Bone Miner Res 24:334-7. 2009
    ..We conclude that in vivo Atorvastatin may not be as effective in modulating the acute phase reaction associated with intravenous bisphosphonate as would have been anticipated from in vitro studies...
  21. ncbi request reprint Utility of follow-up renal sonography in children with vesicoureteral reflux and normal initial sonogram
    Lisa H Lowe
    Department of Radiology, Children s Mercy Hospital and University of Missouri, Kansas City, Missouri 64108, USA
    Pediatrics 113:548-50. 2004
    ....
  22. ncbi request reprint Bilateral nephrectomy reverses hypothyroidism in congenital nephrotic syndrome
    V Chadha
    Section of Pediatric Nephrology, The Children s Mercy Hospital, Kansas City, MO 64108, USA
    Pediatr Nephrol 13:209-11. 1999
    ..Abatement of massive proteinuria enables discontinuation of thyroid supplementation, and a transient rise in TSH in the early post-nephrectomy stage should be potentially expected...
  23. ncbi request reprint Random urine calcium/osmolality in the assessment of calciuria in children with decreased muscle mass
    W Richmond
    Section of Nephrology, Children s Mercy Hospital, University of Missouri, Kansas City, MO 64108, USA
    Clin Nephrol 64:264-70. 2005
    ..Random urine Ca/creatinine (UCa/Cr) is used to estimate 24-hour Ca excretion. However, due to decreased urine creatinine excretion in children with decreased muscle mass (DMM), UCa/Cr overestimates their Ca excretion...
  24. ncbi request reprint Success and safety of same-day kidney biopsy in children and adolescents
    A M Simckes
    Section of Pediatric Nephrology, The Children s Mercy Hospital, Kansas City, MO 64108, USA
    Pediatr Nephrol 14:946-52. 2000
    ..We conclude that in selected patients, same-day discharge after renal biopsy may be performed safely without an increased risk of complications...
  25. ncbi request reprint Antacid-induced rickets in infancy
    A Pattaragarn
    Section of Pediatric Nephrology, Children's Mercy Hospital, University of Missouri at Kansas City, USA
    Clin Pediatr (Phila) 40:389-93. 2001
    ..Pediatricians should avoid or minimize the use of aluminum-containing antacids, and when used, carefully monitor mineral metabolism...
  26. doi request reprint Bisphosphonates in children with hypercalciuria and reduced bone mineral density
    Michael Freundlich
    Pediatric Nephrology, University of Miami, Miami, FL, USA
    Pediatr Nephrol 23:2215-20. 2008
    ..These short-term beneficial effects indicate the need for larger prospective studies on the potential of bisphosphonates to serve as a new tool in treating children with IH and reduced BMD...
  27. doi request reprint Reversal of hypercalcemic acute kidney injury by treatment with intravenous bisphosphonates
    Ari Auron
    Section of Pediatric Nephrology, Blank Children s Hospital, Iowa Health System, Des Moines, IA, USA
    Pediatr Nephrol 24:613-7. 2009
    ..On the basis of cumulative data and our experience, we suggest that i.v. application of bisphosphonates be moved from the second to the first line of treatment of hypercalcemic AKI...
  28. ncbi request reprint Podocyte proteins in Galloway-Mowat syndrome
    T Srivastava
    Section of Nephrology, The Children's Mercy Hospital, University of Missouri at Kansas City, 2401 Gillham Road, Kansas City, MO 64108, USA
    Pediatr Nephrol 16:1022-9. 2001
    ....
  29. ncbi request reprint Pneumonia-associated acute glomerulonephritis
    T Srivastava
    Section of Nephrology, The Children s Mercy Hospital, University of Missouri at Kansas City 61408, USA
    Clin Nephrol 57:175-82. 2002
    ..However, in several children we observed acute glomerulonephritis (AGN) to develop concurrently with pneumonia. The objective of the study was to delineate the clinical course and outcome of pneumonia-associated AGN...
  30. ncbi request reprint Measurement of urinary concentration: a critical appraisal of methodologies
    V Chadha
    Section of Pediatric Nephrology, Children's Mercy Hospital, University of Missouri at Kansas City, 2401 Gillham Road, Kansas City, MO 64108, USA
    Pediatr Nephrol 16:374-82. 2001
    ..For the clinician who is interpreting urine SG results, it is important to be aware of these limitations and understand the reasons for possible potential errors of each particular method...
  31. ncbi request reprint Normal urinary calcium/creatinine ratios in African-American and Caucasian children
    N P So
    Section of Pediatric Nephrology, The Children's Mercy Hospital, University of Missouri at Kansas City, 64108, USA
    Pediatr Nephrol 16:133-9. 2001
    ..Contrary to what has previously been reported in hypercalciuric children, no significant relationship was found between UCa/Cr and UNa/K in healthy children...
  32. ncbi request reprint Citrate clearance in children receiving continuous venovenous renal replacement therapy
    Vimal Chadha
    Section of Pediatric Nephrology, The Children s Mercy Hospital, University of Missouri at Kansas City, Kansas City, Missouri, USA
    Pediatr Nephrol 17:819-24. 2002
    ..Sufficient citrate clearance to prevent its toxic accumulation is achieved by convective clearance (CVVH) alone and diffusive clearance (CVVHDF) does not appear to be mandatory when utilizing citrate anticoagulation during CRRT...
  33. ncbi request reprint The role of bisphosphonates in diseases of childhood
    Tarak Srivastava
    Section of Nephrology, The Children s Mercy Hospital, 2401 Gillham Road, Kansas City, MO 64108, USA
    Eur J Pediatr 162:735-51. 2003
    ....
  34. ncbi request reprint Pathophysiology of hypercalciuria in children
    Tarak Srivastava
    Section of Nephrology, Bone and Mineral Disorder Clinic, The Children s Mercy Hospital and Clinics, University of Missouri, 2401 Gillham Road, Kansas City, MO 64108, USA
    Pediatr Nephrol 22:1659-73. 2007
    ....
  35. ncbi request reprint Timing of follow-up voiding cystourethrogram in children with primary vesicoureteral reflux: development and application of a clinical algorithm
    Matthew Thompson
    Section of Nephrology, Children s Mercy Hospital, University of Missouri, Kansas City, Missour 64108, USA
    Pediatrics 115:426-34. 2005
    ..The objective of this study was to develop a clinically applicable algorithm for the optimal timing of repeat VCUGs and validate this algorithm in a retrospective cohort of children with VUR...
  36. ncbi request reprint Lack of seasonal variations in urinary calcium/creatinine ratio in school-age children
    Michelle Stuart Hilgenfeld
    Section of Nephrology, Children s Mercy Hospital, Kansas City, Missouri 64108, USA
    Pediatr Nephrol 19:1153-5. 2004
    ..Thus the current UCa/Cr value used to diagnose hypercalciuria does not require a seasonal adjustment...
  37. ncbi request reprint Resolution of medullary nephrocalcinosis in children with metabolic bone disorders
    Ari Auron
    Section of Pediatric Nephrology, The Children s Mercy Hospital, University of Missouri at Kansas City School of Medicine, 64108, USA
    Pediatr Nephrol 20:1143-5. 2005
    ..Further studies are suggested to explore the possible role of anticalciuric diuretics in promoting the resolution of NC...
  38. ncbi request reprint Urolithiasis in adolescent children
    Tarak Srivastava
    Section of Nephrology, The Children s Mercy Hospital, 2401 Gillham Road, Kansas City, MO 64108, USA
    Adolesc Med Clin 16:87-109. 2005
    ..In many children and adolescents with urolithiasis, a nonpharmacologic approach involving the adoption of healthy nutrition habits may suffice...
  39. ncbi request reprint Treatment of congenital nephrogenic diabetes insipidus by hydrochlorothiazide and cyclooxygenase-2 inhibitor
    Anirut Pattaragarn
    Section of Pediatric Nephrology, The Children s Mercy Hospital, University of Missouri at Kansas City, Missouri 64108, USA
    Pediatr Nephrol 18:1073-6. 2003
    ..At age 8.5 months, the infant demonstrated catch-up growth and normal neurodevelopmental milestones. We conclude that the combination HCTZ/cyclooxygenase-2 inhibitor could be successfully used to treat infantile cNDI...
  40. ncbi request reprint Ambulatory blood pressure monitoring in children and adolescents
    Ari M Simckes
    Section of Nephrology, The Children s Mercy Hospital, Kansas City, MO 64108, USA
    Clin Pediatr (Phila) 41:549-64. 2002
    ..The role of ABPM in various clinical conditions and hypertension research in children is presented...
  41. ncbi request reprint Sustained beneficial effect of intravenous bisphosphonates after their discontinuation in children
    Kim M Waterhouse
    Bone and Mineral Disorders Clinic, Section of Pediatric Nephrology, The Children s Mercy Hospital and Clinics, University of Missouri Kansas City School of Medicine, Kansas City, MO, USA
    Pediatr Nephrol 22:282-7. 2007
    ..V. bisphosphonates continue to exert their beneficial effect for a mean of 26+/-2 months after their discontinuation; therefore, once therapeutic goals are achieved, the medication can be withheld, followed by periodic re-evaluation...
  42. ncbi request reprint Use of the multipurpose drainage catheter for the provision of acute peritoneal dialysis in infants and children
    Ari Auron
    Section of Pediatric Nephrology, The Children s Mercy Hospitals and Clinics, University of Missouri at Kansas City, MO 64108, USA
    Am J Kidney Dis 49:650-5. 2007
    ....
  43. ncbi request reprint Antibiotic treatment and renal stone formation in cystic fibrosis
    Uri S Alon
    J Pediatr 141:598; author reply 598. 2002
  44. ncbi request reprint Stage I vitamin D-deficiency rickets mimicking pseudohypoparathyroidism type II
    Tarak Srivastava
    Section of Nephrology and Bone and Mineral Disorders Clinic, The Children s Mercy Hospital, University of Missouri at Kansas City 64108, USA
    Clin Pediatr (Phila) 41:263-8. 2002
    ..It has become essential for pediatricians to recognize VDR owing to its resurgence in developed countries...
  45. ncbi request reprint Hearing impairment in familial X-linked hypophosphatemic rickets
    Gadi Fishman
    Department of Pediatric Otolaryngology, Dana Children s Hospital, Tel Aviv Medical Center, Sackler School of Medicine, Tel Aviv University, Tel Aviv, Israel
    Eur J Pediatr 163:622-3. 2004
  46. ncbi request reprint VCUG timing
    Uri S Alon
    J Pediatr 141:146; author reply 146. 2002
  47. ncbi request reprint Vitamin E therapy in IgA nephropathy: a double-blind, placebo-controlled study
    James C M Chan
    Virginia Commonwealth University, Richmond, Virginia, USA
    Pediatr Nephrol 18:1015-9. 2003
    ....

Research Grants1

  1. Tools for mapping transcriptional networks
    Uri Alon; Fiscal Year: 2006
    ..We expect that the analysis tools and concepts developed in E. coli will be very useful in mapping complex regulatory circuits in other cell types. ..