Adan A Aguirre

Summary

Affiliation: Children's National Medical Center
Country: USA

Publications

  1. pmc Reduced EGFR signaling in progenitor cells of the adult subventricular zone attenuates oligodendrogenesis after demyelination
    Adan Aguirre
    Center for Neuroscience Research, Children s National Medical Center, 111 Michigan Avenue, NW Washington, DC 20010, USA
    Neuron Glia Biol 3:209-20. 2007
  2. ncbi Downregulation of platelet-derived growth factor-alpha receptor-mediated tyrosine kinase activity as a cellular mechanism for K+-channel regulation during oligodendrocyte development in situ
    Ramesh Chittajallu
    Center for Neuroscience Research, Children s Research Institute, Children s National Medical Center, Washington, DC 20010, USA
    J Neurosci 25:8601-10. 2005
  3. pmc Postnatal NG2 proteoglycan-expressing progenitor cells are intrinsically multipotent and generate functional neurons
    Shibeshih Belachew
    Center for Neuroscience Research, Children s Research Institute, Children s National Medical Center, Washington, DC 20010 2970, USA
    J Cell Biol 161:169-86. 2003
  4. pmc NG2-expressing cells in the subventricular zone are type C-like cells and contribute to interneuron generation in the postnatal hippocampus
    Adan A Aguirre
    Center for Neuroscience Research, Children s Research Institute, Rm 5345, Children s National Medical Center, 111 Michigan Ave, N W, Washington, DC 20010, USA
    J Cell Biol 165:575-89. 2004
  5. ncbi Cyclin-dependent kinase-2 controls oligodendrocyte progenitor cell cycle progression and is downregulated in adult oligodendrocyte progenitors
    Shibeshih Belachew
    Laboratory of Cellular and Synaptic Neurophysiology, National Institute of Child Health and Human Development, National Institutes of Health, Bethesda, Maryland 20892 4495, USA
    J Neurosci 22:8553-62. 2002

Collaborators

Detail Information

Publications5

  1. pmc Reduced EGFR signaling in progenitor cells of the adult subventricular zone attenuates oligodendrogenesis after demyelination
    Adan Aguirre
    Center for Neuroscience Research, Children s National Medical Center, 111 Michigan Avenue, NW Washington, DC 20010, USA
    Neuron Glia Biol 3:209-20. 2007
    ..Our results demonstrate that the response of NG2(+) cells in the SVZ and their subsequent differentiation in CC after focal demyelination depend on EGFR signaling...
  2. ncbi Downregulation of platelet-derived growth factor-alpha receptor-mediated tyrosine kinase activity as a cellular mechanism for K+-channel regulation during oligodendrocyte development in situ
    Ramesh Chittajallu
    Center for Neuroscience Research, Children s Research Institute, Children s National Medical Center, Washington, DC 20010, USA
    J Neurosci 25:8601-10. 2005
    ..Together, these data indicate that PDGFR-alpha and tyrosine kinase activity act via a common pathway that influences functional expression of K+ channels and proliferative capacity of OPs in situ...
  3. pmc Postnatal NG2 proteoglycan-expressing progenitor cells are intrinsically multipotent and generate functional neurons
    Shibeshih Belachew
    Center for Neuroscience Research, Children s Research Institute, Children s National Medical Center, Washington, DC 20010 2970, USA
    J Cell Biol 161:169-86. 2003
    ..These data show that at least a subpopulation of postnatal NG2-expressing cells are CNS multipotent precursors that may underlie adult hippocampal neurogenesis...
  4. pmc NG2-expressing cells in the subventricular zone are type C-like cells and contribute to interneuron generation in the postnatal hippocampus
    Adan A Aguirre
    Center for Neuroscience Research, Children s Research Institute, Rm 5345, Children s National Medical Center, 111 Michigan Ave, N W, Washington, DC 20010, USA
    J Cell Biol 165:575-89. 2004
    ....
  5. ncbi Cyclin-dependent kinase-2 controls oligodendrocyte progenitor cell cycle progression and is downregulated in adult oligodendrocyte progenitors
    Shibeshih Belachew
    Laboratory of Cellular and Synaptic Neurophysiology, National Institute of Child Health and Human Development, National Institutes of Health, Bethesda, Maryland 20892 4495, USA
    J Neurosci 22:8553-62. 2002
    ....

Research Grants2

  1. A role for EGF receptor signaling in oligodendrocyte development and repair
    Adan Aguirre; Fiscal Year: 2007
    ..Our proposed studies aim to shed light on crucial regulators of oligodendrocyte development and remyelination that are potentially useful in therapeutic strategies. ..