Zhi liang Wu
Affiliation: Cephalon Inc
- Protein tyrosine phosphatases are up-regulated and participate in cell death induced by polyglutamine expansionZhi liang Wu
Cephalon, West Chester, Pennsylvania 19380, USA
J Biol Chem 277:44208-13. 2002..These results suggest that one or more of the PTPs are involved in the polyglutamine-induced cell death...
- Comparative analysis of cortical gene expression in mouse models of Alzheimer's diseaseZhi liang Wu
Cephalon, Inc, Neurobiology, 145 Brandywine Parkway, West Chester, PA 19380 4245, USA
Neurobiol Aging 27:377-86. 2006....
- The phosphatidylinositol 3-kinase inhibitor LY 294002 inhibits GlyT1-mediated glycine uptakeZhi liang Wu
CNS Biology, Cephalon, Inc 145 Brandywine Parkway, West Chester, PA 19380, USA
Brain Res 1227:42-51. 2008..In addition, glycine release was blocked by LY 294002. These results raised a possibility that LY 294002 might interact with GlyT1...
- Inhibition of mixed lineage kinase 3 attenuates MPP+-induced neurotoxicity in SH-SY5Y cellsJoanne R Mathiasen
Neurobiology, Cephalon, Inc, 145 Brandywine Parkway, West Chester, PA 19380, USA
Brain Res 1003:86-97. 2004..These studies show that inhibition of the MLK 3/JNK pathway attenuates MPP(+)-mediated SH-SY5Y cell death in culture and supports the mechanism of action of CEP-1347 as an MLK family inhibitor...