Research Topics
Genomes and GenesSpecies | Berran YucesoySummaryAffiliation: Centers for Disease Control and Prevention Country: USA Publications
| Collaborators
|
Detail Information
Publications
Influence of cytokine gene variations on immunization to childhood vaccinesBerran Yucesoy
Toxicology and Molecular Biology Branch, CDC NIOSH, Morgantown, WV 26505 2888, United States
Vaccine 27:6991-7. 2009..05). These data suggest that genetic variations in cytokine genes can influence vaccine-induced immune responses in infants, which in turn may influence vaccine efficacy...
Genetic susceptibility in pneumoconiosisBerran Yucesoy
Toxicology and Molecular Biology Branch, Health Effects Laboratory Division, National Institute for Occupational Safety and Health, Morgantown, WV 26505, USA
Toxicol Lett 168:249-54. 2007..Therefore, an understanding of genetic variability and the interaction between genetic and environmental factors is crucial to the identification of high-risk individuals and prevention and treatment of these diseases...
Genetic variants in antioxidant genes are associated with diisocyanate-induced asthmaBerran Yucesoy
CDC National Institute for Occupational Safety and Health, Health Effects Laboratory Division, Morgantown, West Virginia 26505, USA
Toxicol Sci 129:166-73. 2012..The GSTM3 rs110913*EPHX1 rs1051741 genotype combination was also associated with DA under this model (p = 0.042). The results suggest that variations in SOD2, GST, and EPHX1 genes and their interactions contribute to DA susceptibility...- Genetic susceptibility to progressive massive fibrosis in coal minersB Yucesoy
Toxicology and Molecular Biology Branch, Centers for Disease Control and Prevention National Institute for Occupational Safety and Health, Morgantown, WV 26505 2888, USA
Eur Respir J 31:1177-82. 2008.... - Association of interleukin-1 gene polymorphisms with dementia in a community-based sample: the Honolulu-Asia Aging StudyBerran Yucesoy
Toxicology and Molecular Biology Branch, Biostatistics Branch, Health Effects Laboratory Division, National Institute for Occupational Safety and Health, 1095 Willowdale Road, Morgantown, WV 26505, USA
Neurobiol Aging 27:211-7. 2006..There was no difference in the IL-1beta (+3953) frequency among the groups. Our results support the hypothesis that certain genetic variations contained within the IL-1 gene family contribute to the pathogenesis of dementia... - Cytokine polymorphisms in chronic inflammatory diseases with reference to occupational diseasesBerran Yucesoy
Ankara University, Faculty of Pharmacy, Department of Toxicology, 06100, Tandogan Ankara, Turkey
Curr Mol Med 3:39-48. 2003..In the present review, the concept that some of the common allelic variants found in cytokine genes represent modifying factors in chronic inflammatory diseases associated with occupational exposure is discussed... - Association of cytokine gene polymorphisms with rate of decline in lung functionBerran Yucesoy
Toxicology and Molecular Biology Branch, Health Effects Laboratory Division, National Institute for Occupational Safety and Health, Morgantown, WV 26505 2888, USA
J Occup Environ Med 50:642-8. 2008..To investigate whether genetic variants involved in cytokine expression are associated with the age-related rate of decline in forced expiratory volume in 1 second (FEV1)... - Association of cytokine gene polymorphisms in CWP and its severity in Turkish coal workersIlker Ates
Faculty of Pharmacy, Department of Toxicology, Ankara University, Ankara, Turkey
Am J Ind Med 51:741-7. 2008..An additional goal was to observe whether these cytokine gene polymorphisms influence the development risk and severity of... - Possible effect of gene polymorphisms on the release of TNFα and IL1 cytokines in coal workers' pneumoconiosisIlker Ates
Department of Toxicology, Faculty of Pharmacy, Ankara University, Tandogan, Ankara 06100, Turkey
Exp Toxicol Pathol 63:175-9. 2011..These data suggest that the coal dust-induced release of TNF-alpha from monocytes may be a useful biomarker of CWP... - Prevention of IL-1 signaling attenuates airway hyperresponsiveness and inflammation in a murine model of toluene diisocyanate-induced asthmaVictor J Johnson
Toxicology and Molecular Biology Branch, Health Effects Laboratory Division, National Institute for Occupational Safety and Health, Centers for Disease Control and Prevention, Morgantown, WV 26505 2888, USA
J Allergy Clin Immunol 116:851-8. 2005.... - Inhalation of toluene diisocyanate vapor induces allergic rhinitis in miceVictor J Johnson
Toxicology and Molecular Biology Branch, Health Effects Laboratory Division, National Institute for Occupational Safety and Health, Centers for Disease Control and Prevention, Morgantown, WV 26505, USA
J Immunol 179:1864-71. 2007..Future studies will use this model to define disease mechanisms and examine the temporal/dose relationship between TDI-induced rhinitis and asthma... - Association between IL-1A single nucleotide polymorphisms and chronic beryllium disease and beryllium sensitizationErin C McCanlies
Health Effects Laboratory Division, National Institute for Occupational Safety and Health, Centers for Disease Control and Prevention, Morgantown, WV 26505, USA
J Occup Environ Med 52:680-4. 2010..To determine if single nucleotide polymorphisms (SNPs) in interleukin (IL) IL-1A, IL-1B, IL-1RN, IL-2, IL-9, and IL-9R were associated with chronic beryllium disease (CBD) and beryllium sensitization (BeS)... - IL-1beta gene polymorphisms influence hepatitis B vaccinationBerran Yucesoy
National Institute for Occupational Safety and Health, 1095 Willowdale Road, Morgantown, WV 26508, USA
Vaccine 20:3193-6. 2002.... - Cytokine polymorphisms in silicosis and other pneumoconiosesBerran Yucesoy
Ankara University, Faculty of Pharmacy, Department of Toxicology, Turkey
Mol Cell Biochem 234:219-24. 2002..In this review we discuss genetic polymorphisms responsible for regulating the production of these proinflammatory cytokines and their role in modifying silicosis severity... - Significance of genetic information in risk assessment and individual classification using silicosis as a case modelErin McCanlies
Biostatistics Branch, Health Effects Laboratory Division, National Institute for Occupational Safety and Health, Morgantown, WV 26505, USA
Ann Occup Hyg 46:375-81. 2002..However, in the case of fibrotic lung disease caused by silica exposure, information about the presence or absence of the minor variants of IL-1alpha, IL-1RA and TNFalpha is unlikely to be a useful tool for individual classification... - Biomarkers to assess potential developmental immunotoxicity in childrenMichael I Luster
Toxicology and Molecular Biology Branch, Health Effects Laboratory Division, National Institute for Occupational Safety and Health, Centers for Disease Control and Prevention, 1095 Willowdale Road, Morgantown, WV 26505, USA
Toxicol Appl Pharmacol 206:229-36. 2005..Quantification of the immune response to childhood vaccine, while up to the present used sparingly, may represent an excellent indicator for developmental immunotoxicity when conducted under appropriate conditions... - Genotyping of single nucleotide polymorphisms in cytokine genes using real-time PCR allelic discrimination technologyVictor J Johnson
Toxicology and Molecular Biology Branch, Health Effects Laboratory Division, National Institute for Occupational Safety and Health, Centers for Disease Control and Prevention, Morgantown, WV 26505, USA
Cytokine 27:135-41. 2004..4%. The public databases of cytokine polymorphisms and validated genotyping assays highlighted in the present study will greatly benefit this important field of research... - Cytogenetic monitoring of coal workers and patients with coal workers' pneumoconiosis in TurkeyOzge Cemiloglu Ulker
Department of Toxicology, Faculty of Pharmacy, Ankara University, Ankara, Turkey
Environ Mol Mutagen 49:232-7. 2008..This is the first report on CWP patients with elevated cytogenetic endpoints. Further, a larger follow-up study is warranted... - Insights into the quantitative relationship between sensitization and challenge for allergic contact dermatitis reactionsAaron E Scott
Toxicology and Molecular Biology Branch, National Institute for Occupational Safety and Health, Morgantown, West Virginia 26505, USA
Toxicol Appl Pharmacol 183:66-70. 2002..Taken together, these findings indicate that there is a need to consider dose-response relationships for sensitization and challenge in establishing minimum exposure levels for chemicals that cause ACD... - Neopterin as a marker for immune system activation in coal workers' pneumoconiosisOzge C Ulker
Department of Toxicology, Ankara University, Ankara, Turkey
Toxicol Ind Health 23:155-60. 2007..05). These findings indicate that elevated serum and BAL levels of neopterin may be considered as a suitable biomarker for the assessment of CWP... - Inhalation of ortho-phthalaldehyde vapor causes respiratory sensitization in miceVictor J Johnson
Toxicology and Molecular Biology Branch, Health Effects Laboratory Division, National Institute for Occupational Safety and Health, Centers for Disease Control and Prevention, Morgantown, WV 26505 2888, USA
J Allergy (Cairo) 2011:751052. 2011..Mice exposed to the higher concentrations of OPA-produced OPA-specific IgG(1) antibodies indicating systemic sensitization. These findings provide evidence that OPA has the potential to cause respiratory sensitization in mice... - Genetic variability in susceptibility to occupational respiratory sensitizationBerran Yucesoy
Toxicology and Molecular Biology Branch, Health Effects Laboratory Division, National Institute for Occupational Safety and Health, Centers for Disease Control and Prevention, Morgantown, WV 26505, USA
J Allergy (Cairo) 2011:346719. 2011..This paper will focus on the current state of knowledge regarding genetic influences on allergic respiratory diseases, with specific emphasis on diisocyanate-induced asthma and chronic beryllium disease... - Diseases caused by silica: mechanisms of injury and disease developmentMin Ding
Pathology and Physiology Research Branch, Health Effects Laboratory Division, National Institute for Occupational Safety and Health, Morgantown, WV 26505, USA
Int Immunopharmacol 2:173-82. 2002..Silica-induced AP-1 activation, protooncogene expression, and the role of ROS in these processes are also briefly discussed... - Effects of occupational polycyclic aromatic hydrocarbon exposure on T-lymphocyte functions and natural killer cell activity in asphalt and coke oven workersAsuman Karakaya
Ankara University, Faculty of Pharmacy, Department of Toxicology, Tandogan, Ankara, Turkey
Hum Exp Toxicol 23:317-22. 2004..Our results are in line with others reported in the literature indicating that chronic exposure to PAHs at different levels may alter some immune responses in different ways... - A statistical model for assessing genetic susceptibility as a risk factor in multifactorial diseases: lessons from occupational asthmaEugene Demchuk
Division of Toxicology and Environmental Medicine, Agency for Toxic Substances and Disease Registry, Centers for Disease Control and Prevention, Atlanta, Georgia, USA
Environ Health Perspect 115:231-4. 2007..The genetic components most responsible for differences in individual disease risk are thought to be DNA variants (polymorphisms) that influence the expression or function of mediators involved in the pathological processes... - Cytokine genotype and phenotype effects on lung function decline in firefightersArun B Josyula
Division of Community, Environment and Policy, Mel and Enid Zuckerman College of Public Health, University of Arizona, Tucson, AZ 85724 5210, USA
J Occup Environ Med 49:282-8. 2007..We conducted this study to evaluate the association of cytokine genotypes and sputum concentrations on longitudinal decline in lung function in firefighters... - A TGF-beta1 polymorphism association with dementia and neuropathologies: the HAASRita Peila
Laboratory of Epidemiology, Demography and Biometry, National Institute on Aging, National Institutes of Health, 7201 Wisconsin Avenue, Suite 3C 309, Bethesda, MD 20892 9205, USA
Neurobiol Aging 28:1367-73. 2007..2-0.9). The CC genotype was associated with an increase risk of neocortical plaques (OR(CC)=4.34, CI: 1.6-11.8). These preliminary data suggest that the TGF genetic variability may be important in the risk of vascular related dementia... - Cytokine polymorphisms play a role in susceptibility to ultraviolet B-induced modulation of immune responses after hepatitis B vaccinationAnnemarie Sleijffers
National Institute of Public Health and the Environment, Bilthoven, The Netherlands
J Immunol 170:3423-8. 2003..This study indicates that individual susceptibility to UVB radiation needs to be considered when studying the effects of UVB in humans... - Diisocyanate asthma and gene-environment interactions with IL4RA, CD-14, and IL-13 genesDavid I Bernstein
Department of Internal Medicine, Division of Immunology, University of Cincinnati Medical Center, Cincinnati, Ohio, USA
Ann Allergy Asthma Immunol 97:800-6. 2006..Diisocyanate asthma (DA) affects 2% to 10% of exposed workers, yet the pathogenetic mechanisms underlying this disorder remain ill defined...