Research Topics
| Wei YuSummaryAffiliation: Centers for Disease Control and Prevention Country: USA Publications
| Collaborators
|
Detail Information
Publications
Tracking the epidemiology of human genes in the literature: the HuGE Published Literature databaseBruce K Lin
Office of Genomics and Disease Prevention, Coordinating Center for Health Promotion, Centers for Disease Control and Prevention, Atlanta, GA 30341, USA
Am J Epidemiol 164:1-4. 2006..Here, the authors provide an overview of the database and its characteristics and uses...
A navigator for human genome epidemiologyWei Yu
Nat Genet 40:124-5. 2008
GAPscreener: an automatic tool for screening human genetic association literature in PubMed using the support vector machine techniqueWei Yu
National Office of Public Health Genomics, Coordinating Center for Health Promotion, Centers for Disease Control and Prevention, Atlanta, GA, USA
BMC Bioinformatics 9:205. 2008..The GAPscreener, a free SVM-based software tool, can be used to assist in screening PubMed abstracts for human genetic association studies...
Gene Prospector: an evidence gateway for evaluating potential susceptibility genes and interacting risk factors for human diseasesWei Yu
National Office of Public Health Genomics, Coordinating Center for Health Promotion, Centers for Disease Control and Prevention, Atlanta, GA, USA
BMC Bioinformatics 9:528. 2008..The application, called Gene Prospector, also provides a comprehensive set of links to additional data sources...
An open source infrastructure for managing knowledge and finding potential collaborators in a domain-specific subset of PubMed, with an example from human genome epidemiologyWei Yu
National Office of Public Health Genomics, Coordinating Center for Health Promotion, Centers for Disease Control and Prevention, Atlanta, GA, USA
BMC Bioinformatics 8:436. 2007..The design of this infrastructure makes the system potentially extensible to other data sources...
The need for genetic variant naming standards in published abstracts of human genetic association studiesWei Yu
Office of Public Health Genomics, Centers for Disease Control and Prevention, Atlanta, Georgia 30341, USA
BMC Res Notes 2:56. 2009..The consistent use of rs numbers in abstracts that report genetic associations would enhance knowledge synthesis and translation in this field...
An automatic method to generate domain-specific investigator networks using PubMed abstractsWei Yu
National Office of Public Health Genomics, Coordinating Center for Health Promotion, Centers for Disease Control and Prevention, Atlanta, GA, USA
BMC Med Inform Decis Mak 7:17. 2007..We present a novel strategy for building investigator networks dynamically and producing detailed investigator profiles using data available in PubMed abstracts...
Application of support vector machine modeling for prediction of common diseases: the case of diabetes and pre-diabetesWei Yu
National Office of Public Health Genomics, Coordinating Center for Health Promotion, Centers for Disease Control and Prevention, Atlanta, GA, USA
BMC Med Inform Decis Mak 10:16. 2010..We illustrate the method to detect persons with diabetes and pre-diabetes in a cross-sectional representative sample of the U.S. population...
GWAS Integrator: a bioinformatics tool to explore human genetic associations reported in published genome-wide association studiesWei Yu
Office of Public Health Genomics, Centers for Disease Control and Prevention, Atlanta, GA 30341, USA
Eur J Hum Genet 19:1095-9. 2011..hugenavigator.net/HuGENavigator/gWAHitStartPage.do). The GWAS Integrator may help enhance inference on potential genetic associations identified from GWAS studies...
HuGE Watch: tracking trends and patterns of published studies of genetic association and human genome epidemiology in near-real timeWei Yu
National Office of Public Health Genomics, Coordinating Center for Health Promotion, Centers for Disease Control and Prevention, Atlanta, GA 30341, USA
Eur J Hum Genet 16:1155-8. 2008..The application allows users to display temporal trends and spatial distributions as line charts and google maps, providing a quick overview of progress in the field. http://www.hugenavigator.net/HuGENavigator/startPageWatch.do..
Reporting of human genome epidemiology (HuGE) association studies: an empirical assessmentAjay Yesupriya
National Office of Public Health Genomics, Coordinating Center for Health Promotion, Centers for Disease Control and Prevention, Atlanta, USA
BMC Med Res Methodol 8:31. 2008..Transparent reporting of study methods and results allows readers to better assess the validity of study findings. Here, we document reporting practices of human genome epidemiology studies...
Trends in population-based studies of human genetics in infectious diseasesJessica L Rowell
Office of Public Health Genomics, Office of Epidemiology, Surveillance, and Laboratory Services, Centers for Disease Control and Prevention, Atlanta, Georgia, United States of America
PLoS ONE 7:e25431. 2012..This approach offers new opportunities for understanding infectious disease susceptibility, severity, treatment, control, and prevention...
Genome-wide association studies, field synopses, and the development of the knowledge base on genetic variation and human diseasesMuin J Khoury
Office of Public Health Genomics, National Center for Chronic Disease Prevention and Health Promotion, Centers for Disease Control and Prevention, Atlanta, GA 30341, USA
Am J Epidemiol 170:269-79. 2009..As a next step in the evolution of Human Genome Epidemiology reviews, the authors invite investigators to submit field synopses for possible publication in the American Journal of Epidemiology...
Horizon scanning for new genomic testsMarta Gwinn
McKing Consulting Corporation, Atlanta, Georgia, USA
Genet Med 13:161-5. 2011..Consequently, it is not easy to determine which tests are in development, currently available, or discontinued. We developed and assessed the usefulness of a systematic approach to identifying new genomic tests on the Internet...
Genetic epidemiology with a capital E, ten years afterMuin J Khoury
Office of Public Health Genomics, Centers for Disease Control and Prevention, 1600 Clifton Road, Atlanta GA 30333, USA
Genet Epidemiol 35:845-52. 2011..We extend Duncan Thomas' capital E to include "Evaluation" as the tools of epidemiology are increasingly used to assess how genome-based information can be applied in medicine and public health...
Identification and quantification of coronary atherosclerotic plaques: a comparison of 64-MDCT and intravascular ultrasoundJunyan Sun
Department of Radiology, Beijing An Zhen Hospital, Capital Medical University, An Ding Men Wai An Zhen Li, Chao Yang District, 100029, Beijing, China
AJR Am J Roentgenol 190:748-54. 2008..The purpose of this study was to compare the accuracy of 64-MDCT with that of intravascular ultrasound (IVUS) for the identification and quantitative analysis of coronary atherosclerotic plaques...
Survival and aging in the wild via residual demographyHans Georg Muller
Department of Statistics, University of California, Davis, One Shields Ave, Davis, CA 95616, USA
Theor Popul Biol 72:513-22. 2007..Several extensions are discussed. Residual demography is demonstrated for data on fruit flies Bactrocera oleae...
Development and validation of a CGH microarray for clinical cytogenetic diagnosisSau W Cheung
Department of Molecular and Human Genetics, Baylor College of Medicine, One Baylor Plaza, Houston, TX 77030, USA
Genet Med 7:422-32. 2005..Limitations of CMA include the inability to detect both balanced chromosome changes and low levels of mosaicism...
[Bone mineral density and leptin receptor polymorphism Gln223Arg in Han women in Beijing]Jie Jiao
Department of Endocrinology, Peking Union Medical College Hospital, Peking Union Medical College, Chinese Academy of Medical Sciences, Beijing 100730, China
Zhonghua Nei Ke Za Zhi 43:276-9. 2004..To investigate the association between bone mineral density (BMD) and leptin receptor (LEPR) polymorphism (Gln223 Arg) in young women and postmenopausl osteoporotic women...
Development of a comparative genomic hybridization microarray and demonstration of its utility with 25 well-characterized 1p36 deletionsWei Yu
Department of Molecular and Human Genetics, Baylor College of Medicine, Houston, TX, USA
Hum Mol Genet 12:2145-52. 2003..We anticipate that array CGH will change the diagnostic approach to many congenital and acquired genetic diseases such as mental retardation, birth defects and cancer...
