Ajay Yesupriya

Summary

Affiliation: Centers for Disease Control and Prevention
Country: USA

Publications

  1. doi request reprint Sodium intake and blood pressure among US children and adolescents
    Quanhe Yang
    Division for Heart Disease and Stroke Prevention, Centers for Disease Control and Prevention, 4770 Buford Highway, Mailstop F 72, Atlanta, GA 30341, USA
    Pediatrics 130:611-9. 2012
  2. doi request reprint Prospective study of methylenetetrahydrofolate reductase (MTHFR) variant C677T and risk of all-cause and cardiovascular disease mortality among 6000 US adults
    Quanhe Yang
    Office of Public Health Genomics, CDC, Atlanta, GA 30341, USA
    Am J Clin Nutr 95:1245-53. 2012
  3. doi request reprint Trends in cardiovascular health metrics and associations with all-cause and CVD mortality among US adults
    Quanhe Yang
    Division for Heart Disease and Stroke Prevention, Centers for Disease Control and Prevention, 4770 Buford Hwy NE, MS F 72, Atlanta, GA 30341, USA
    JAMA 307:1273-83. 2012
  4. pmc Using lifetime risk estimates in personal genomic profiles: estimation of uncertainty
    Quanhe Yang
    Office of Public Health Genomics, Centers for Disease Control and Prevention, Atlanta, GA 30333, USA
    Am J Hum Genet 85:786-800. 2009
  5. doi request reprint Folic acid source, usual intake, and folate and vitamin B-12 status in US adults: National Health and Nutrition Examination Survey (NHANES) 2003-2006
    Quanhe Yang
    Office of Public Health Genomics, Centers for Disease Control and Prevention, Atlanta, GA 30333, USA
    Am J Clin Nutr 91:64-72. 2010
  6. doi request reprint Serum folate and cancer mortality among U.S. adults: findings from the Third National Health and Nutritional Examination Survey linked mortality file
    Quanhe Yang
    Centers for Disease Control and Prevention, Atlanta, GA 30333, USA
    Cancer Epidemiol Biomarkers Prev 18:1439-47. 2009
  7. pmc Improvements in ability to detect undiagnosed diabetes by using information on family history among adults in the United States
    Quanhe Yang
    Centers for Disease Control and Prevention, Atlanta, GA 30333, USA
    Am J Epidemiol 171:1079-89. 2010
  8. ncbi request reprint Prevalence and effects of gene-gene and gene-nutrient interactions on serum folate and serum total homocysteine concentrations in the United States: findings from the third National Health and Nutrition Examination Survey DNA Bank
    Quan He Yang
    National Center on Birth Defects and Developmental Disabilities, Centers for Disease Control and Prevention, Atlanta, GA 30341, USA
    Am J Clin Nutr 88:232-46. 2008
  9. ncbi request reprint The return of thalidomide: are birth defects surveillance systems ready?
    Q Yang
    Division of Birth Defects and Developmental Disabilities, National Center for Environmental Health, Centers for Disease Control and Prevention, Atlanta, Georgia, USA
    Am J Med Genet 73:251-8. 1997
  10. pmc Racial/ethnic differences in association of fasting glucose-associated genomic loci with fasting glucose, HOMA-B, and impaired fasting glucose in the U.S. adult population
    Quanhe Yang
    Office of Public Health Genomics, Centers for Disease Control and Prevention, Atlanta, Georgia, USA
    Diabetes Care 33:2370-7. 2010

Detail Information

Publications39

  1. doi request reprint Sodium intake and blood pressure among US children and adolescents
    Quanhe Yang
    Division for Heart Disease and Stroke Prevention, Centers for Disease Control and Prevention, 4770 Buford Highway, Mailstop F 72, Atlanta, GA 30341, USA
    Pediatrics 130:611-9. 2012
    ..To assess the association between usual dietary sodium intake and blood pressure among US children and adolescents, overall and by weight status...
  2. doi request reprint Prospective study of methylenetetrahydrofolate reductase (MTHFR) variant C677T and risk of all-cause and cardiovascular disease mortality among 6000 US adults
    Quanhe Yang
    Office of Public Health Genomics, CDC, Atlanta, GA 30341, USA
    Am J Clin Nutr 95:1245-53. 2012
    ....
  3. doi request reprint Trends in cardiovascular health metrics and associations with all-cause and CVD mortality among US adults
    Quanhe Yang
    Division for Heart Disease and Stroke Prevention, Centers for Disease Control and Prevention, 4770 Buford Hwy NE, MS F 72, Atlanta, GA 30341, USA
    JAMA 307:1273-83. 2012
    ....
  4. pmc Using lifetime risk estimates in personal genomic profiles: estimation of uncertainty
    Quanhe Yang
    Office of Public Health Genomics, Centers for Disease Control and Prevention, Atlanta, GA 30333, USA
    Am J Hum Genet 85:786-800. 2009
    ..Epidemiologic parameters involved in computation of disease risk have substantial uncertainty, and cumulative uncertainty should be properly recognized. Reliance on point estimates alone could be seriously misleading...
  5. doi request reprint Folic acid source, usual intake, and folate and vitamin B-12 status in US adults: National Health and Nutrition Examination Survey (NHANES) 2003-2006
    Quanhe Yang
    Office of Public Health Genomics, Centers for Disease Control and Prevention, Atlanta, GA 30333, USA
    Am J Clin Nutr 91:64-72. 2010
    ..US adults have access to multiple sources of folic acid. The contribution of these sources to usual intakes above the tolerable upper intake level (UL) (1000 microg/d) and to folate and vitamin B-12 status is unknown...
  6. doi request reprint Serum folate and cancer mortality among U.S. adults: findings from the Third National Health and Nutritional Examination Survey linked mortality file
    Quanhe Yang
    Centers for Disease Control and Prevention, Atlanta, GA 30333, USA
    Cancer Epidemiol Biomarkers Prev 18:1439-47. 2009
    ....
  7. pmc Improvements in ability to detect undiagnosed diabetes by using information on family history among adults in the United States
    Quanhe Yang
    Centers for Disease Control and Prevention, Atlanta, GA 30333, USA
    Am J Epidemiol 171:1079-89. 2010
    ..Study findings suggest that adding family history of diabetes can provide significant improvements in detecting undiagnosed diabetes in the US population. Further research is needed to validate the authors' findings...
  8. ncbi request reprint Prevalence and effects of gene-gene and gene-nutrient interactions on serum folate and serum total homocysteine concentrations in the United States: findings from the third National Health and Nutrition Examination Survey DNA Bank
    Quan He Yang
    National Center on Birth Defects and Developmental Disabilities, Centers for Disease Control and Prevention, Atlanta, GA 30341, USA
    Am J Clin Nutr 88:232-46. 2008
    ..Folate intake and genetic polymorphisms encoding folate-metabolizing enzymes influence blood folate and homocysteine concentrations, but the effects and interactions of these factors have not been studied on a population-wide basis...
  9. ncbi request reprint The return of thalidomide: are birth defects surveillance systems ready?
    Q Yang
    Division of Birth Defects and Developmental Disabilities, National Center for Environmental Health, Centers for Disease Control and Prevention, Atlanta, Georgia, USA
    Am J Med Genet 73:251-8. 1997
    ..Our findings highlight the importance of enlarging the monitored population and correct case classification in birth defects surveillance...
  10. pmc Racial/ethnic differences in association of fasting glucose-associated genomic loci with fasting glucose, HOMA-B, and impaired fasting glucose in the U.S. adult population
    Quanhe Yang
    Office of Public Health Genomics, Centers for Disease Control and Prevention, Atlanta, Georgia, USA
    Diabetes Care 33:2370-7. 2010
    ....
  11. doi request reprint Sodium and potassium intake and mortality among US adults: prospective data from the Third National Health and Nutrition Examination Survey
    Quanhe Yang
    Division for Heart Diseases and Stroke Prevention, Centers for Disease Control and Prevention, 4770 Buford Hwy NE, Mail Stop K 47, Atlanta, GA 30341, USA
    Arch Intern Med 171:1183-91. 2011
    ..Few studies have examined joint effects of dietary sodium and potassium intake on risk of mortality...
  12. ncbi request reprint Risk factors for trisomy 21: maternal cigarette smoking and oral contraceptive use in a population-based case-control study
    Q Yang
    Division of Birth Defects and Developmental Disabilities and the Office of Genetics and Disease Prevention, National Center for Environmental Health, Centers for Disease Control and Prevention, Atlanta, Georgia 30341, USA
    Genet Med 1:80-8. 1999
    ..This is the first epidemiological study to categorize cases of trisomy 21 by parent of origin and timing of the meiotic error before assessing possible risk factors...
  13. ncbi request reprint Method of weighted proportion of reproductive-aged women taking folic acid supplements to predict a neural tube defect rate decline
    Quanhe Yang
    Division of Birth Defects and Developmental Disabilities, National Center on Birth Defects and Developmental Disabilities, Centers for Disease Control and Prevention, Atlanta, Georgia 30333, USA
    Birth Defects Res A Clin Mol Teratol 67:959-67. 2003
    ..In this study we examine the potential error in using the crude proportion to predict NTD risk reduction, and offer an alternative method...
  14. ncbi request reprint How many genes underlie the occurrence of common complex diseases in the population?
    Quanhe Yang
    National Center on Birth Defects and Developmental Disabilities, Centers for Disease Control and Prevention CDC, Atlanta, GA 30333, USA
    Int J Epidemiol 34:1129-37. 2005
    ..It is not clear how many genes are necessary to account for an appreciable population-attributable fraction of these diseases...
  15. ncbi request reprint Improvement in stroke mortality in Canada and the United States, 1990 to 2002
    Quanhe Yang
    National Center on Birth Defects and Developmental Disabilities, Centers for Disease Control and Prevention, Atlanta, GA 30333, USA
    Circulation 113:1335-43. 2006
    ..The resulting population-wide reduction in blood homocysteine concentrations might be expected to reduce stroke mortality if high homocysteine levels are an independent risk factor for stroke...
  16. pmc Associations of maternal age- and parity-related factors with trends in low-birthweight rates: United States, 1980 through 2000
    Quanhe Yang
    Division of Birth Defects and Developmental Disabilities, National Center on Birth Defects and Developmental Disabilities, Centers for Disease Control and Prevention, 1600 Clifton Rd, Mail Stop E 86, Atlanta, GA 30333, USA
    Am J Public Health 96:856-61. 2006
    ..We assessed the effects of changes in the maternal age-parity distribution and age-and parity-specific low-birthweight rates on low-birthweight trends in the United States...
  17. ncbi request reprint Racial differences in infant mortality attributable to birth defects in the United States, 1989-2002
    Quanhe Yang
    National Center on Birth Defects and Developmental Disabilities, Centers for Disease Control and Prevention CDC, Atlanta, Georgia 30333, USA
    Birth Defects Res A Clin Mol Teratol 76:706-13. 2006
    ..The objective is to study racial differences in infant mortality attributable to birth defects (IMBD) in the United States...
  18. doi request reprint A Hardy-Weinberg equilibrium test for analyzing population genetic surveys with complex sample designs
    Ramal Moonesinghe
    Office of Minority Health and Health Disparities, 4770 Buford Highway, Mailstop E 67, Atlanta, GA 30341, USA
    Am J Epidemiol 171:932-41. 2010
    ....
  19. pmc Genetic variants associated with fasting blood lipids in the U.S. population: Third National Health and Nutrition Examination Survey
    Man Huei Chang
    National Office of Public Health Genomics, Centers for Disease Control and Prevention, Atlanta, GA, USA
    BMC Med Genet 11:62. 2010
    ..S. population...
  20. doi request reprint Racial/ethnic variation in the association of lipid-related genetic variants with blood lipids in the US adult population
    Man Huei Chang
    Office of Public Health Genomics, Centers for Disease Control and Prevention, Atlanta, GA 30333, USA
    Circ Cardiovasc Genet 4:523-33. 2011
    ..The individual and the cumulative effect of these SNPs on blood lipids are largely unclear for the US population...
  21. pmc Influence of familial risk on diabetes risk-reducing behaviors among U.S. adults without diabetes
    Man Huei Chang
    Office of Public Health Genomics, Centers for Disease Control and Prevention, Atlanta, Georgia, USA
    Diabetes Care 34:2393-9. 2011
    ..To test the association of family history of diabetes with the adoption of diabetes risk-reducing behaviors and whether this association is strengthened by physician advice or commonly known factors associated with diabetes risk...
  22. doi request reprint The ACE I/D polymorphism in US adults: limited evidence of association with hypertension-related traits and sex-specific effects by race/ethnicity
    Renee M Ned
    Office of Public Health Genomics, Centers for Disease Control and Prevention, Atlanta, Georgia, USA
    Am J Hypertens 25:209-15. 2012
    ..The evidence to date, however, on an association of this variant with blood pressure-related outcomes has been inconclusive...
  23. pmc Prevalence in the United States of selected candidate gene variants: Third National Health and Nutrition Examination Survey, 1991-1994
    Man Huei Chang
    National Office of Public Health Genomics, Centers for Disease Control and Prevention, Atlanta, GA 30341, USA
    Am J Epidemiol 169:54-66. 2009
    ..These nationally representative data on allele frequency and genotype prevalence provide a valuable resource for future epidemiologic studies in public health in the United States...
  24. pmc GAPscreener: an automatic tool for screening human genetic association literature in PubMed using the support vector machine technique
    Wei Yu
    National Office of Public Health Genomics, Coordinating Center for Health Promotion, Centers for Disease Control and Prevention, Atlanta, GA, USA
    BMC Bioinformatics 9:205. 2008
    ..The GAPscreener, a free SVM-based software tool, can be used to assist in screening PubMed abstracts for human genetic association studies...
  25. doi request reprint Variants in ABCB1, TGFB1, and XRCC1 genes and susceptibility to viral hepatitis A infection in Mexican Americans
    Lyna Zhang
    Office of Public Health Genomics, National Center for HIV AIDS, Viral Hepatitis, STD, and TB Prevention, Centers for Diseases Control and Prevention, 1600 Clifton Road NE, Atlanta, GA 30333, USA
    Hepatology 55:1008-18. 2012
    ..71-0.89; FDR-P = 0.0007). Conclusion: Genetic variants in ABCB1, TGFB1, and XRCC1 appear to be associated with susceptibility to HAV infection among Mexican Americans. Replication studies involving larger population samples are warranted...
  26. pmc An open source infrastructure for managing knowledge and finding potential collaborators in a domain-specific subset of PubMed, with an example from human genome epidemiology
    Wei Yu
    National Office of Public Health Genomics, Coordinating Center for Health Promotion, Centers for Disease Control and Prevention, Atlanta, GA, USA
    BMC Bioinformatics 8:436. 2007
    ..The design of this infrastructure makes the system potentially extensible to other data sources...
  27. pmc GWAS Integrator: a bioinformatics tool to explore human genetic associations reported in published genome-wide association studies
    Wei Yu
    Office of Public Health Genomics, Centers for Disease Control and Prevention, Atlanta, GA 30341, USA
    Eur J Hum Genet 19:1095-9. 2011
    ..hugenavigator.net/HuGENavigator/gWAHitStartPage.do). The GWAS Integrator may help enhance inference on potential genetic associations identified from GWAS studies...
  28. pmc Gene polymorphisms in association with emerging cardiovascular risk markers in adult women
    Amy Z Fan
    National Center for Chronic Disease Prevention and Health Promotion, Centers for Disease Control and Prevention, 1600 Clifton Road, Atlanta, GA 30333, USA
    BMC Med Genet 11:6. 2010
    ..This population-based study is aimed to determine the presence of associations between a wide array of genetic variants and emerging cardiovascular risk markers among adult US women...
  29. pmc Inflammation gene variants and susceptibility to albuminuria in the U.S. population: analysis in the Third National Health and Nutrition Examination Survey (NHANES III), 1991-1994
    Renee M Ned
    Office of Public Health Genomics, Office of Surveillance, Epidemiology, and Laboratory Services, Centers for Disease Control and Prevention, Atlanta, GA, USA
    BMC Med Genet 11:155. 2010
    ..While the underlying etiology is unclear, chronic, low-grade inflammation is a suspected key factor. Genetic variants within genes involved in inflammatory processes may, therefore, contribute to the development of albuminuria...
  30. pmc Gene polymorphisms in association with self-reported stroke in US adults
    Amy Z Fan
    National Center for Chronic Disease Prevention and Health Promotion, Centers for Disease Control and Prevention, Atlanta, GA, USA
    Appl Clin Genet 3:23-8. 2010
    ..We identified polymorphisms associated with the prevalence of self-reported stroke in US populations using a representative sample...
  31. ncbi request reprint HuGE Watch: tracking trends and patterns of published studies of genetic association and human genome epidemiology in near-real time
    Wei Yu
    National Office of Public Health Genomics, Coordinating Center for Health Promotion, Centers for Disease Control and Prevention, Atlanta, GA 30341, USA
    Eur J Hum Genet 16:1155-8. 2008
    ..The application allows users to display temporal trends and spatial distributions as line charts and google maps, providing a quick overview of progress in the field. http://www.hugenavigator.net/HuGENavigator/startPageWatch.do..
  32. pmc Reporting of human genome epidemiology (HuGE) association studies: an empirical assessment
    Ajay Yesupriya
    National Office of Public Health Genomics, Coordinating Center for Health Promotion, Centers for Disease Control and Prevention, Atlanta, USA
    BMC Med Res Methodol 8:31. 2008
    ..Transparent reporting of study methods and results allows readers to better assess the validity of study findings. Here, we document reporting practices of human genome epidemiology studies...
  33. pmc Trends in population-based studies of human genetics in infectious diseases
    Jessica L Rowell
    Office of Public Health Genomics, Office of Epidemiology, Surveillance, and Laboratory Services, Centers for Disease Control and Prevention, Atlanta, Georgia, United States of America
    PLoS ONE 7:e25431. 2012
    ..This approach offers new opportunities for understanding infectious disease susceptibility, severity, treatment, control, and prevention...
  34. pmc Modification by ALAD of the association between blood lead and blood pressure in the U.S. population: results from the Third National Health and Nutrition Examination Survey
    Franco Scinicariello
    Division of Toxicology and Environmental Medicine, Agency for Toxic Substances and Disease Registry, Atlanta, Georgia 30341, USA
    Environ Health Perspect 118:259-64. 2010
    ..Individuals vary greatly in susceptibility to lead toxicity, and genetic susceptibility has often been cited as the probable cause for such variation...
  35. doi request reprint Lead and cognitive function in VDR genotypes in the third National Health and Nutrition Examination Survey
    Edward F Krieg
    National Institute for Occupational Safety and Health, Cincinnati, Ohio 45226, USA
    Neurotoxicol Teratol 32:262-72. 2010
    ..The mean blood lead concentrations of the children and adults did not vary by VDR genotype...
  36. ncbi request reprint Lead and cognitive function in ALAD genotypes in the third National Health and Nutrition Examination Survey
    Edward F Krieg
    National Institute for Occupational Safety and Health, Robert A Taft Laboratories, Cincinnati, Ohio 45226, USA
    Neurotoxicol Teratol 31:364-71. 2009
    ..The mean blood lead concentration of children with the ALAD rs1800435 CC/CG genotype was less than that of children with the GG genotype...
  37. pmc Association between immunoglobulin GM and KM genotypes and placental malaria in HIV-1 negative and positive women in western Kenya
    Nnaemeka C Iriemenam
    Division of Parasitic Diseases and Malaria, Center for Global Health, Centers for Disease Control and Prevention, Atlanta, Georgia, United States of America
    PLoS ONE 8:e53948. 2013
    ..The deficit in heterozygotes for GM6 further suggests that GM6 could be under selection likely by malaria infection...
  38. pmc An automatic method to generate domain-specific investigator networks using PubMed abstracts
    Wei Yu
    National Office of Public Health Genomics, Coordinating Center for Health Promotion, Centers for Disease Control and Prevention, Atlanta, GA, USA
    BMC Med Inform Decis Mak 7:17. 2007
    ..We present a novel strategy for building investigator networks dynamically and producing detailed investigator profiles using data available in PubMed abstracts...
  39. doi request reprint Trends in laboratory test volumes for Medicare Part B reimbursements, 2000-2010
    Shahram Shahangian
    From the Division of Laboratory Programs, Standards, and Services, Center for Surveillance, Epidemiology, and Laboratory Services, Centers for Disease Control and Prevention, Atlanta, Georgia Drs Shahangian and Astles and Messrs Yesupriya and Alspach
    Arch Pathol Lab Med 138:189-203. 2014
    ..To date, however, there has been no report, to our knowledge, of longitudinal trends in national laboratory test use...