Research Topics
Genomes and Genes
Species | Ajay YesupriyaSummaryAffiliation: Centers for Disease Control and Prevention Country: USA Publications
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Detail Information
Publications
Sodium intake and blood pressure among US children and adolescentsQuanhe Yang
Division for Heart Disease and Stroke Prevention, Centers for Disease Control and Prevention, 4770 Buford Highway, Mailstop F 72, Atlanta, GA 30341, USA
Pediatrics 130:611-9. 2012..To assess the association between usual dietary sodium intake and blood pressure among US children and adolescents, overall and by weight status...- Prospective study of methylenetetrahydrofolate reductase (MTHFR) variant C677T and risk of all-cause and cardiovascular disease mortality among 6000 US adultsQuanhe Yang
Office of Public Health Genomics, CDC, Atlanta, GA 30341, USA
Am J Clin Nutr 95:1245-53. 2012.... - Trends in cardiovascular health metrics and associations with all-cause and CVD mortality among US adultsQuanhe Yang
Division for Heart Disease and Stroke Prevention, Centers for Disease Control and Prevention, 4770 Buford Hwy NE, MS F 72, Atlanta, GA 30341, USA
JAMA 307:1273-83. 2012.... - Serum folate and cancer mortality among U.S. adults: findings from the Third National Health and Nutritional Examination Survey linked mortality fileQuanhe Yang
Centers for Disease Control and Prevention, Atlanta, GA 30333, USA
Cancer Epidemiol Biomarkers Prev 18:1439-47. 2009.... - Folic acid source, usual intake, and folate and vitamin B-12 status in US adults: National Health and Nutrition Examination Survey (NHANES) 2003-2006Quanhe Yang
Office of Public Health Genomics, Centers for Disease Control and Prevention, Atlanta, GA 30333, USA
Am J Clin Nutr 91:64-72. 2010..US adults have access to multiple sources of folic acid. The contribution of these sources to usual intakes above the tolerable upper intake level (UL) (1000 microg/d) and to folate and vitamin B-12 status is unknown... 
Using lifetime risk estimates in personal genomic profiles: estimation of uncertaintyQuanhe Yang
Office of Public Health Genomics, Centers for Disease Control and Prevention, Atlanta, GA 30333, USA
Am J Hum Genet 85:786-800. 2009..Epidemiologic parameters involved in computation of disease risk have substantial uncertainty, and cumulative uncertainty should be properly recognized. Reliance on point estimates alone could be seriously misleading...
The return of thalidomide: are birth defects surveillance systems ready?Q Yang
Division of Birth Defects and Developmental Disabilities, National Center for Environmental Health, Centers for Disease Control and Prevention, Atlanta, Georgia, USA
Am J Med Genet 73:251-8. 1997..Our findings highlight the importance of enlarging the monitored population and correct case classification in birth defects surveillance...- Improvements in ability to detect undiagnosed diabetes by using information on family history among adults in the United StatesQuanhe Yang
Centers for Disease Control and Prevention, Atlanta, GA 30333, USA
Am J Epidemiol 171:1079-89. 2010..Study findings suggest that adding family history of diabetes can provide significant improvements in detecting undiagnosed diabetes in the US population. Further research is needed to validate the authors' findings... - Racial/ethnic differences in association of fasting glucose-associated genomic loci with fasting glucose, HOMA-B, and impaired fasting glucose in the U.S. adult populationQuanhe Yang
Office of Public Health Genomics, Centers for Disease Control and Prevention, Atlanta, Georgia, USA
Diabetes Care 33:2370-7. 2010.... - Sodium and potassium intake and mortality among US adults: prospective data from the Third National Health and Nutrition Examination SurveyQuanhe Yang
Division for Heart Diseases and Stroke Prevention, Centers for Disease Control and Prevention, 4770 Buford Hwy NE, Mail Stop K 47, Atlanta, GA 30341, USA
Arch Intern Med 171:1183-91. 2011..Few studies have examined joint effects of dietary sodium and potassium intake on risk of mortality... - Prevalence and effects of gene-gene and gene-nutrient interactions on serum folate and serum total homocysteine concentrations in the United States: findings from the third National Health and Nutrition Examination Survey DNA BankQuan He Yang
National Center on Birth Defects and Developmental Disabilities, Centers for Disease Control and Prevention, Atlanta, GA 30341, USA
Am J Clin Nutr 88:232-46. 2008..Folate intake and genetic polymorphisms encoding folate-metabolizing enzymes influence blood folate and homocysteine concentrations, but the effects and interactions of these factors have not been studied on a population-wide basis... - Associations of maternal age- and parity-related factors with trends in low-birthweight rates: United States, 1980 through 2000Quanhe Yang
Division of Birth Defects and Developmental Disabilities, National Center on Birth Defects and Developmental Disabilities, Centers for Disease Control and Prevention, 1600 Clifton Rd, Mail Stop E 86, Atlanta, GA 30333, USA
Am J Public Health 96:856-61. 2006..We assessed the effects of changes in the maternal age-parity distribution and age-and parity-specific low-birthweight rates on low-birthweight trends in the United States... - Risk factors for trisomy 21: maternal cigarette smoking and oral contraceptive use in a population-based case-control studyQ Yang
Division of Birth Defects and Developmental Disabilities and the Office of Genetics and Disease Prevention, National Center for Environmental Health, Centers for Disease Control and Prevention, Atlanta, Georgia 30341, USA
Genet Med 1:80-8. 1999..This is the first epidemiological study to categorize cases of trisomy 21 by parent of origin and timing of the meiotic error before assessing possible risk factors... - How many genes underlie the occurrence of common complex diseases in the population?Quanhe Yang
National Center on Birth Defects and Developmental Disabilities, Centers for Disease Control and Prevention CDC, Atlanta, GA 30333, USA
Int J Epidemiol 34:1129-37. 2005..It is not clear how many genes are necessary to account for an appreciable population-attributable fraction of these diseases... - Improvement in stroke mortality in Canada and the United States, 1990 to 2002Quanhe Yang
National Center on Birth Defects and Developmental Disabilities, Centers for Disease Control and Prevention, Atlanta, GA 30333, USA
Circulation 113:1335-43. 2006..The resulting population-wide reduction in blood homocysteine concentrations might be expected to reduce stroke mortality if high homocysteine levels are an independent risk factor for stroke... - Method of weighted proportion of reproductive-aged women taking folic acid supplements to predict a neural tube defect rate declineQuanhe Yang
Division of Birth Defects and Developmental Disabilities, National Center on Birth Defects and Developmental Disabilities, Centers for Disease Control and Prevention, Atlanta, Georgia 30333, USA
Birth Defects Res A Clin Mol Teratol 67:959-67. 2003..In this study we examine the potential error in using the crude proportion to predict NTD risk reduction, and offer an alternative method... - Racial differences in infant mortality attributable to birth defects in the United States, 1989-2002Quanhe Yang
National Center on Birth Defects and Developmental Disabilities, Centers for Disease Control and Prevention CDC, Atlanta, Georgia 30333, USA
Birth Defects Res A Clin Mol Teratol 76:706-13. 2006..The objective is to study racial differences in infant mortality attributable to birth defects (IMBD) in the United States... - A Hardy-Weinberg equilibrium test for analyzing population genetic surveys with complex sample designsRamal Moonesinghe
Office of Minority Health and Health Disparities, 4770 Buford Highway, Mailstop E 67, Atlanta, GA 30341, USA
Am J Epidemiol 171:932-41. 2010.... - Genetic variants associated with fasting blood lipids in the U.S. population: Third National Health and Nutrition Examination SurveyMan Huei Chang
National Office of Public Health Genomics, Centers for Disease Control and Prevention, Atlanta, GA, USA
BMC Med Genet 11:62. 2010..S. population... - Racial/ethnic variation in the association of lipid-related genetic variants with blood lipids in the US adult populationMan Huei Chang
Office of Public Health Genomics, Centers for Disease Control and Prevention, Atlanta, GA 30333, USA
Circ Cardiovasc Genet 4:523-33. 2011..The individual and the cumulative effect of these SNPs on blood lipids are largely unclear for the US population... - Influence of familial risk on diabetes risk-reducing behaviors among U.S. adults without diabetesMan Huei Chang
Office of Public Health Genomics, Centers for Disease Control and Prevention, Atlanta, Georgia, USA
Diabetes Care 34:2393-9. 2011..To test the association of family history of diabetes with the adoption of diabetes risk-reducing behaviors and whether this association is strengthened by physician advice or commonly known factors associated with diabetes risk... - The ACE I/D polymorphism in US adults: limited evidence of association with hypertension-related traits and sex-specific effects by race/ethnicityRenee M Ned
Office of Public Health Genomics, Centers for Disease Control and Prevention, Atlanta, Georgia, USA
Am J Hypertens 25:209-15. 2012..The evidence to date, however, on an association of this variant with blood pressure-related outcomes has been inconclusive... - Prevalence in the United States of selected candidate gene variants: Third National Health and Nutrition Examination Survey, 1991-1994Man Huei Chang
National Office of Public Health Genomics, Centers for Disease Control and Prevention, Atlanta, GA 30341, USA
Am J Epidemiol 169:54-66. 2009..These nationally representative data on allele frequency and genotype prevalence provide a valuable resource for future epidemiologic studies in public health in the United States... - GAPscreener: an automatic tool for screening human genetic association literature in PubMed using the support vector machine techniqueWei Yu
National Office of Public Health Genomics, Coordinating Center for Health Promotion, Centers for Disease Control and Prevention, Atlanta, GA, USA
BMC Bioinformatics 9:205. 2008..The GAPscreener, a free SVM-based software tool, can be used to assist in screening PubMed abstracts for human genetic association studies... - Variants in ABCB1, TGFB1, and XRCC1 genes and susceptibility to viral hepatitis A infection in Mexican AmericansLyna Zhang
Office of Public Health Genomics, National Center for HIV AIDS, Viral Hepatitis, STD, and TB Prevention, Centers for Diseases Control and Prevention, 1600 Clifton Road NE, Atlanta, GA 30333, USA
Hepatology 55:1008-18. 2012..71-0.89; FDR-P = 0.0007). Conclusion: Genetic variants in ABCB1, TGFB1, and XRCC1 appear to be associated with susceptibility to HAV infection among Mexican Americans. Replication studies involving larger population samples are warranted... - An open source infrastructure for managing knowledge and finding potential collaborators in a domain-specific subset of PubMed, with an example from human genome epidemiologyWei Yu
National Office of Public Health Genomics, Coordinating Center for Health Promotion, Centers for Disease Control and Prevention, Atlanta, GA, USA
BMC Bioinformatics 8:436. 2007..The design of this infrastructure makes the system potentially extensible to other data sources... - GWAS Integrator: a bioinformatics tool to explore human genetic associations reported in published genome-wide association studiesWei Yu
Office of Public Health Genomics, Centers for Disease Control and Prevention, Atlanta, GA 30341, USA
Eur J Hum Genet 19:1095-9. 2011..hugenavigator.net/HuGENavigator/gWAHitStartPage.do). The GWAS Integrator may help enhance inference on potential genetic associations identified from GWAS studies... - Gene polymorphisms in association with emerging cardiovascular risk markers in adult womenAmy Z Fan
National Center for Chronic Disease Prevention and Health Promotion, Centers for Disease Control and Prevention, 1600 Clifton Road, Atlanta, GA 30333, USA
BMC Med Genet 11:6. 2010..This population-based study is aimed to determine the presence of associations between a wide array of genetic variants and emerging cardiovascular risk markers among adult US women... - Inflammation gene variants and susceptibility to albuminuria in the U.S. population: analysis in the Third National Health and Nutrition Examination Survey (NHANES III), 1991-1994Renee M Ned
Office of Public Health Genomics, Office of Surveillance, Epidemiology, and Laboratory Services, Centers for Disease Control and Prevention, Atlanta, GA, USA
BMC Med Genet 11:155. 2010..While the underlying etiology is unclear, chronic, low-grade inflammation is a suspected key factor. Genetic variants within genes involved in inflammatory processes may, therefore, contribute to the development of albuminuria... - Reporting of human genome epidemiology (HuGE) association studies: an empirical assessmentAjay Yesupriya
National Office of Public Health Genomics, Coordinating Center for Health Promotion, Centers for Disease Control and Prevention, Atlanta, USA
BMC Med Res Methodol 8:31. 2008..Transparent reporting of study methods and results allows readers to better assess the validity of study findings. Here, we document reporting practices of human genome epidemiology studies... - HuGE Watch: tracking trends and patterns of published studies of genetic association and human genome epidemiology in near-real timeWei Yu
National Office of Public Health Genomics, Coordinating Center for Health Promotion, Centers for Disease Control and Prevention, Atlanta, GA 30341, USA
Eur J Hum Genet 16:1155-8. 2008..The application allows users to display temporal trends and spatial distributions as line charts and google maps, providing a quick overview of progress in the field. http://www.hugenavigator.net/HuGENavigator/startPageWatch.do.. - Trends in population-based studies of human genetics in infectious diseasesJessica L Rowell
Office of Public Health Genomics, Office of Epidemiology, Surveillance, and Laboratory Services, Centers for Disease Control and Prevention, Atlanta, Georgia, United States of America
PLoS ONE 7:e25431. 2012..This approach offers new opportunities for understanding infectious disease susceptibility, severity, treatment, control, and prevention... - Modification by ALAD of the association between blood lead and blood pressure in the U.S. population: results from the Third National Health and Nutrition Examination SurveyFranco Scinicariello
Division of Toxicology and Environmental Medicine, Agency for Toxic Substances and Disease Registry, Atlanta, Georgia 30341, USA
Environ Health Perspect 118:259-64. 2010..Individuals vary greatly in susceptibility to lead toxicity, and genetic susceptibility has often been cited as the probable cause for such variation... - Lead and cognitive function in ALAD genotypes in the third National Health and Nutrition Examination SurveyEdward F Krieg
National Institute for Occupational Safety and Health, Robert A Taft Laboratories, Cincinnati, Ohio 45226, USA
Neurotoxicol Teratol 31:364-71. 2009..The mean blood lead concentration of children with the ALAD rs1800435 CC/CG genotype was less than that of children with the GG genotype... - Lead and cognitive function in VDR genotypes in the third National Health and Nutrition Examination SurveyEdward F Krieg
National Institute for Occupational Safety and Health, Cincinnati, Ohio 45226, USA
Neurotoxicol Teratol 32:262-72. 2010..The mean blood lead concentrations of the children and adults did not vary by VDR genotype... - An automatic method to generate domain-specific investigator networks using PubMed abstractsWei Yu
National Office of Public Health Genomics, Coordinating Center for Health Promotion, Centers for Disease Control and Prevention, Atlanta, GA, USA
BMC Med Inform Decis Mak 7:17. 2007..We present a novel strategy for building investigator networks dynamically and producing detailed investigator profiles using data available in PubMed abstracts...