Research Topics
Genomes and Genes
Species | Ajay YesupriyaSummaryAffiliation: Centers for Disease Control and Prevention Country: USA Publications
| Collaborators
|
Detail Information
Publications
Reporting of human genome epidemiology (HuGE) association studies: an empirical assessmentAjay Yesupriya
National Office of Public Health Genomics, Coordinating Center for Health Promotion, Centers for Disease Control and Prevention, Atlanta, USA
BMC Med Res Methodol 8:31. 2008..Transparent reporting of study methods and results allows readers to better assess the validity of study findings. Here, we document reporting practices of human genome epidemiology studies...
Racial/ethnic variation in the association of lipid-related genetic variants with blood lipids in the US adult populationMan Huei Chang
Office of Public Health Genomics, Centers for Disease Control and Prevention, Atlanta, GA 30333, USA
Circ Cardiovasc Genet 4:523-33. 2011..The individual and the cumulative effect of these SNPs on blood lipids are largely unclear for the US population...
A Hardy-Weinberg equilibrium test for analyzing population genetic surveys with complex sample designsRamal Moonesinghe
Office of Minority Health and Health Disparities, 4770 Buford Highway, Mailstop E 67, Atlanta, GA 30341, USA
Am J Epidemiol 171:932-41. 2010....
GAPscreener: an automatic tool for screening human genetic association literature in PubMed using the support vector machine techniqueWei Yu
National Office of Public Health Genomics, Coordinating Center for Health Promotion, Centers for Disease Control and Prevention, Atlanta, GA, USA
BMC Bioinformatics 9:205. 2008..The GAPscreener, a free SVM-based software tool, can be used to assist in screening PubMed abstracts for human genetic association studies...
The ACE I/D polymorphism in US adults: limited evidence of association with hypertension-related traits and sex-specific effects by race/ethnicityRenee M Ned
Office of Public Health Genomics, Centers for Disease Control and Prevention, Atlanta, Georgia, USA
Am J Hypertens 25:209-15. 2012..The evidence to date, however, on an association of this variant with blood pressure-related outcomes has been inconclusive...
Variants in ABCB1, TGFB1, and XRCC1 genes and susceptibility to viral hepatitis A infection in Mexican AmericansLyna Zhang
Office of Public Health Genomics, National Center for HIV AIDS, Viral Hepatitis, STD, and TB Prevention, Centers for Diseases Control and Prevention, 1600 Clifton Road NE, Atlanta, GA 30333, USA
Hepatology 55:1008-18. 2012..71-0.89; FDR-P = 0.0007). Conclusion: Genetic variants in ABCB1, TGFB1, and XRCC1 appear to be associated with susceptibility to HAV infection among Mexican Americans. Replication studies involving larger population samples are warranted...
Genetic variants associated with fasting blood lipids in the U.S. population: Third National Health and Nutrition Examination SurveyMan Huei Chang
National Office of Public Health Genomics, Centers for Disease Control and Prevention, Atlanta, GA, USA
BMC Med Genet 11:62. 2010..S. population...
Racial/ethnic differences in association of fasting glucose-associated genomic loci with fasting glucose, HOMA-B, and impaired fasting glucose in the U.S. adult populationQuanhe Yang
Office of Public Health Genomics, Centers for Disease Control and Prevention, Atlanta, Georgia, USA
Diabetes Care 33:2370-7. 2010....
Inflammation gene variants and susceptibility to albuminuria in the U.S. population: analysis in the Third National Health and Nutrition Examination Survey (NHANES III), 1991-1994Renee M Ned
Office of Public Health Genomics, Office of Surveillance, Epidemiology, and Laboratory Services, Centers for Disease Control and Prevention, Atlanta, GA, USA
BMC Med Genet 11:155. 2010..While the underlying etiology is unclear, chronic, low-grade inflammation is a suspected key factor. Genetic variants within genes involved in inflammatory processes may, therefore, contribute to the development of albuminuria...
Influence of familial risk on diabetes risk-reducing behaviors among U.S. adults without diabetesMan Huei Chang
Office of Public Health Genomics, Centers for Disease Control and Prevention, Atlanta, Georgia, USA
Diabetes Care 34:2393-9. 2011..To test the association of family history of diabetes with the adoption of diabetes risk-reducing behaviors and whether this association is strengthened by physician advice or commonly known factors associated with diabetes risk...
An open source infrastructure for managing knowledge and finding potential collaborators in a domain-specific subset of PubMed, with an example from human genome epidemiologyWei Yu
National Office of Public Health Genomics, Coordinating Center for Health Promotion, Centers for Disease Control and Prevention, Atlanta, GA, USA
BMC Bioinformatics 8:436. 2007..The design of this infrastructure makes the system potentially extensible to other data sources...
HuGE Watch: tracking trends and patterns of published studies of genetic association and human genome epidemiology in near-real timeWei Yu
National Office of Public Health Genomics, Coordinating Center for Health Promotion, Centers for Disease Control and Prevention, Atlanta, GA 30341, USA
Eur J Hum Genet 16:1155-8. 2008..The application allows users to display temporal trends and spatial distributions as line charts and google maps, providing a quick overview of progress in the field. http://www.hugenavigator.net/HuGENavigator/startPageWatch.do..
GWAS Integrator: a bioinformatics tool to explore human genetic associations reported in published genome-wide association studiesWei Yu
Office of Public Health Genomics, Centers for Disease Control and Prevention, Atlanta, GA 30341, USA
Eur J Hum Genet 19:1095-9. 2011..hugenavigator.net/HuGENavigator/gWAHitStartPage.do). The GWAS Integrator may help enhance inference on potential genetic associations identified from GWAS studies...
Prospective study of methylenetetrahydrofolate reductase (MTHFR) variant C677T and risk of all-cause and cardiovascular disease mortality among 6000 US adultsQuanhe Yang
Office of Public Health Genomics, CDC, Atlanta, GA 30341, USA
Am J Clin Nutr 95:1245-53. 2012....
Trends in population-based studies of human genetics in infectious diseasesJessica L Rowell
Office of Public Health Genomics, Office of Epidemiology, Surveillance, and Laboratory Services, Centers for Disease Control and Prevention, Atlanta, Georgia, United States of America
PLoS ONE 7:e25431. 2012..This approach offers new opportunities for understanding infectious disease susceptibility, severity, treatment, control, and prevention...
Lead and cognitive function in VDR genotypes in the third National Health and Nutrition Examination SurveyEdward F Krieg
National Institute for Occupational Safety and Health, Cincinnati, Ohio 45226, USA
Neurotoxicol Teratol 32:262-72. 2010..The mean blood lead concentrations of the children and adults did not vary by VDR genotype...
Lead and cognitive function in ALAD genotypes in the third National Health and Nutrition Examination SurveyEdward F Krieg
National Institute for Occupational Safety and Health, Robert A Taft Laboratories, Cincinnati, Ohio 45226, USA
Neurotoxicol Teratol 31:364-71. 2009..The mean blood lead concentration of children with the ALAD rs1800435 CC/CG genotype was less than that of children with the GG genotype...
Gene polymorphisms in association with emerging cardiovascular risk markers in adult womenAmy Z Fan
National Center for Chronic Disease Prevention and Health Promotion, Centers for Disease Control and Prevention, 1600 Clifton Road, Atlanta, GA 30333, USA
BMC Med Genet 11:6. 2010..This population-based study is aimed to determine the presence of associations between a wide array of genetic variants and emerging cardiovascular risk markers among adult US women...
Modification by ALAD of the association between blood lead and blood pressure in the U.S. population: results from the Third National Health and Nutrition Examination SurveyFranco Scinicariello
Division of Toxicology and Environmental Medicine, Agency for Toxic Substances and Disease Registry, Atlanta, Georgia 30341, USA
Environ Health Perspect 118:259-64. 2010..Individuals vary greatly in susceptibility to lead toxicity, and genetic susceptibility has often been cited as the probable cause for such variation...
An automatic method to generate domain-specific investigator networks using PubMed abstractsWei Yu
National Office of Public Health Genomics, Coordinating Center for Health Promotion, Centers for Disease Control and Prevention, Atlanta, GA, USA
BMC Med Inform Decis Mak 7:17. 2007..We present a novel strategy for building investigator networks dynamically and producing detailed investigator profiles using data available in PubMed abstracts...
Prevalence in the United States of selected candidate gene variants: Third National Health and Nutrition Examination Survey, 1991-1994Man Huei Chang
National Office of Public Health Genomics, Centers for Disease Control and Prevention, Atlanta, GA 30341, USA
Am J Epidemiol 169:54-66. 2009..These nationally representative data on allele frequency and genotype prevalence provide a valuable resource for future epidemiologic studies in public health in the United States...
A navigator for human genome epidemiologyWei Yu
Nat Genet 40:124-5. 2008
