Research Topics
Species | Quanhe YangSummaryAffiliation: Centers for Disease Control and Prevention Country: USA Publications
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Detail Information
Publications
Mortality associated with Down's syndrome in the USA from 1983 to 1997: a population-based studyQuanhe Yang
National Center on Birth Defects and Developmental Disabilities, Centers for Disease Control and Prevention, 4770 Buford Highway, MS F 45, Atlanta, GA 30341, USA
Lancet 359:1019-25. 2002..Down's syndrome is the most frequently identified cause of mental retardation, but information about mortality and comorbidity in people with Down's syndrome is limited...- Influence of reporting error on the relation between blood folate concentrations and reported folic acid-containing dietary supplement use among reproductive-aged women in the United StatesQuanhe Yang
National Center on Birth Defects and Developmental Disabilities, Centers for Disease Control and Prevention, Atlanta, GA 30341, USA
Am J Clin Nutr 77:196-203. 2003..Folic acid intake is the most important predictor of blood folate concentrations among nonpregnant women, but the reporting of folic acid-containing supplement use is subject to error... 
Improving the prediction of complex diseases by testing for multiple disease-susceptibility genesQuanhe Yang
National Center on Birth Defects and Developmental Disabilities, Centers for Disease Control and Prevention, Atlanta, GA 30341, USA
Am J Hum Genet 72:636-49. 2003..Multiplex genetic testing has the potential to improve the clinical validity of predictive testing for common multifactorial diseases...
Racial/ethnic variation in the association of lipid-related genetic variants with blood lipids in the US adult populationMan Huei Chang
Office of Public Health Genomics, Centers for Disease Control and Prevention, Atlanta, GA 30333, USA
Circ Cardiovasc Genet 4:523-33. 2011..The individual and the cumulative effect of these SNPs on blood lipids are largely unclear for the US population...- Influence of familial risk on diabetes risk-reducing behaviors among U.S. adults without diabetesMan Huei Chang
Office of Public Health Genomics, Centers for Disease Control and Prevention, Atlanta, Georgia, USA
Diabetes Care 34:2393-9. 2011..To test the association of family history of diabetes with the adoption of diabetes risk-reducing behaviors and whether this association is strengthened by physician advice or commonly known factors associated with diabetes risk... - Sodium intake and blood pressure among US children and adolescentsQuanhe Yang
Division for Heart Disease and Stroke Prevention, Centers for Disease Control and Prevention, 4770 Buford Highway, Mailstop F 72, Atlanta, GA 30341, USA
Pediatrics 130:611-9. 2012..To assess the association between usual dietary sodium intake and blood pressure among US children and adolescents, overall and by weight status... - Trends in cardiovascular health metrics and associations with all-cause and CVD mortality among US adultsQuanhe Yang
Division for Heart Disease and Stroke Prevention, Centers for Disease Control and Prevention, 4770 Buford Hwy NE, MS F 72, Atlanta, GA 30341, USA
JAMA 307:1273-83. 2012.... - Folic acid source, usual intake, and folate and vitamin B-12 status in US adults: National Health and Nutrition Examination Survey (NHANES) 2003-2006Quanhe Yang
Office of Public Health Genomics, Centers for Disease Control and Prevention, Atlanta, GA 30333, USA
Am J Clin Nutr 91:64-72. 2010..US adults have access to multiple sources of folic acid. The contribution of these sources to usual intakes above the tolerable upper intake level (UL) (1000 microg/d) and to folate and vitamin B-12 status is unknown... - Sodium and potassium intake and mortality among US adults: prospective data from the Third National Health and Nutrition Examination SurveyQuanhe Yang
Division for Heart Diseases and Stroke Prevention, Centers for Disease Control and Prevention, 4770 Buford Hwy NE, Mail Stop K 47, Atlanta, GA 30341, USA
Arch Intern Med 171:1183-91. 2011..Few studies have examined joint effects of dietary sodium and potassium intake on risk of mortality... - Prospective study of methylenetetrahydrofolate reductase (MTHFR) variant C677T and risk of all-cause and cardiovascular disease mortality among 6000 US adultsQuanhe Yang
Office of Public Health Genomics, CDC, Atlanta, GA 30341, USA
Am J Clin Nutr 95:1245-53. 2012.... - Estimating the contribution of genetic variants to difference in incidence of disease between population groupsRamal Moonesinghe
Office of Minority Health and Health Disparities, Centers for Disease Control and Prevention, Atlanta, GA 30341, USA
Eur J Hum Genet 20:831-6. 2012..Any estimate of genetic contribution to the disparity in incidence of disease between two populations at this stage seems to be an elusive goal... - Autosomal trisomy and maternal use of multivitamin supplementsLorenzo D Botto
National Center on Birth Defects and Developmental Disabilities, Centers for Disease Control and Prevention, Atlanta, Georgia 30333, USA
Am J Med Genet A 125:113-6. 2004..3) for Down syndrome and 1.4 (95% CI, 0.5-3.6) for trisomies 13 and 18, with little variation by maternal race or age. Periconceptional multivitamin use was not associated with a major reduction in the risk for common autosomal trisomies... - How many genes underlie the occurrence of common complex diseases in the population?Quanhe Yang
National Center on Birth Defects and Developmental Disabilities, Centers for Disease Control and Prevention CDC, Atlanta, GA 30333, USA
Int J Epidemiol 34:1129-37. 2005..It is not clear how many genes are necessary to account for an appreciable population-attributable fraction of these diseases... - Trends in the postfortification prevalence of spina bifida and anencephaly in the United StatesSheree L Boulet
National Center on Birth Defects and Developmental Disabilities, CDC, Atlanta, Georgia 30333, USA
Birth Defects Res A Clin Mol Teratol 82:527-32. 2008.... - Sodium and potassium intakes among US adults: NHANES 2003-2008Mary E Cogswell
Division for Heart Disease and Stroke Prevention, CDC, Atlanta, GA 30341, USA
Am J Clin Nutr 96:647-57. 2012.... - Genomic DNA methylation changes in response to folic acid supplementation in a population-based intervention study among women of reproductive ageKrista S Crider
Division of Birth Defects and Developmental Disabilities, National Center on Birth Defects and Developmental Disabilities, Centers for Disease Control and Prevention, Atlanta, Georgia, United States of America
PLoS ONE 6:e28144. 2011.... - Racial/ethnic differences in association of fasting glucose-associated genomic loci with fasting glucose, HOMA-B, and impaired fasting glucose in the U.S. adult populationQuanhe Yang
Office of Public Health Genomics, Centers for Disease Control and Prevention, Atlanta, Georgia, USA
Diabetes Care 33:2370-7. 2010.... - Improvement in stroke mortality in Canada and the United States, 1990 to 2002Quanhe Yang
National Center on Birth Defects and Developmental Disabilities, Centers for Disease Control and Prevention, Atlanta, GA 30333, USA
Circulation 113:1335-43. 2006..The resulting population-wide reduction in blood homocysteine concentrations might be expected to reduce stroke mortality if high homocysteine levels are an independent risk factor for stroke... - Using lifetime risk estimates in personal genomic profiles: estimation of uncertaintyQuanhe Yang
Office of Public Health Genomics, Centers for Disease Control and Prevention, Atlanta, GA 30333, USA
Am J Hum Genet 85:786-800. 2009..Epidemiologic parameters involved in computation of disease risk have substantial uncertainty, and cumulative uncertainty should be properly recognized. Reliance on point estimates alone could be seriously misleading... - Counterpoint: uncertainty in the economic analysis of school-based obesity prevention programs: urgent need for quality evaluationLi Yan Wang
Division of Adolescent and School Health and National Center on Birth Defects and Developmental Disability, Centers for Disease Control and Prevention, Atlanta, Georgia, USA
Obesity (Silver Spring) 14:1483-4. 2006 - Does the MTHFR 677C-->T variant affect the Recommended Dietary Allowance for folate in the US population?Julie Robitaille
National Center on Birth Defects and Developmental Disabilities, Centers for Diseases Control and Prevention, Atlanta, GA, USA
Am J Clin Nutr 89:1269-73. 2009..The effect of this variant on the Recommended Dietary Allowance (RDA) for folate is unclear... - Serum folate and cancer mortality among U.S. adults: findings from the Third National Health and Nutritional Examination Survey linked mortality fileQuanhe Yang
Centers for Disease Control and Prevention, Atlanta, GA 30333, USA
Cancer Epidemiol Biomarkers Prev 18:1439-47. 2009.... - Improvements in ability to detect undiagnosed diabetes by using information on family history among adults in the United StatesQuanhe Yang
Centers for Disease Control and Prevention, Atlanta, GA 30333, USA
Am J Epidemiol 171:1079-89. 2010..Study findings suggest that adding family history of diabetes can provide significant improvements in detecting undiagnosed diabetes in the US population. Further research is needed to validate the authors' findings... - Trends in pediatric sickle cell disease-related mortality in the United States, 1983-2002Emad Yanni
National Center on Birth Defects and Developmental Disabilities, Centers for Disease Control and Prevention, Atlanta, GA 30333, USA
J Pediatr 154:541-5. 2009..To analyze trends in sickle cell disease (SCD)-related mortality among black children during 1983-2002... - On the use of population attributable fraction to determine sample size for case-control studies of gene-environment interactionQuanhe Yang
National Center on Birth Defects and Developmental Disabilities, Centers for Disease Control and Prevention, Atlanta, GA 30341, USA
Epidemiology 14:161-7. 2003..In this case, the associated odds ratio for interaction will be weaker and a considerably larger sample size may be needed... - Trends and racial disparities in muscular dystrophy deaths in the United States, 1983-1998: an analysis of multiple cause mortality dataAileen Kenneson
National Center on Birth Defects and Developmental Disabilities, Centers for Disease Control and Prevention, Atlanta, Georgia 30333, USA
Am J Med Genet A 140:2289-97. 2006..We also present a method for estimating autosomal and X-linked contributions to the overall mortality rate of a genetically heterogeneous condition such as MD... - Population-based analyses of mortality in trisomy 13 and trisomy 18Sonja A Rasmussen
National Center on Birth Defects and Developmental Disabilities, Centers for Disease Control and Prevention, Atlanta, Georgia, USA
Pediatrics 111:777-84. 2003..Although trisomy 13 and trisomy 18 are generally considered to be lethal, long-term survival of patients has been reported. We sought to evaluate mortality in people with trisomy 13 or 18 using 2 population-based strategies... - Associations of maternal age- and parity-related factors with trends in low-birthweight rates: United States, 1980 through 2000Quanhe Yang
Division of Birth Defects and Developmental Disabilities, National Center on Birth Defects and Developmental Disabilities, Centers for Disease Control and Prevention, 1600 Clifton Rd, Mail Stop E 86, Atlanta, GA 30333, USA
Am J Public Health 96:856-61. 2006..We assessed the effects of changes in the maternal age-parity distribution and age-and parity-specific low-birthweight rates on low-birthweight trends in the United States... - An epidemiologic assessment of genomic profiling for measuring susceptibility to common diseases and targeting interventionsMuin J Khoury
Office of Genomics and Disease Prevention, Center on Birth Defects and Developmental Disabilities, Centers for Disease Control and Prevention, Atlanta, Georgia, USA
Genet Med 6:38-47. 2004..CONCLUSION: To assess the value of genomic profiling, well-designed epidemiologic studies are needed to quantify disease risks, in addition to costs, benefits, and risks for testing and interventions... - Status of cardiovascular health among adult Americans in the 50 States and the District of Columbia, 2009Jing Fang
Division for Heart Disease and Stroke Prevention, National Center for Chronic Disease Prevention and Health Promotion, Centers for Disease Control and Prevention, Atlanta, GA, USA
J Am Heart Assoc 1:e005371. 2012..Determining how the metrics vary by state is important to the individual states as well as to researchers and policy makers nationwide... - Method of weighted proportion of reproductive-aged women taking folic acid supplements to predict a neural tube defect rate declineQuanhe Yang
Division of Birth Defects and Developmental Disabilities, National Center on Birth Defects and Developmental Disabilities, Centers for Disease Control and Prevention, Atlanta, Georgia 30333, USA
Birth Defects Res A Clin Mol Teratol 67:959-67. 2003..In this study we examine the potential error in using the crude proportion to predict NTD risk reduction, and offer an alternative method... - Economic analysis of a school-based obesity prevention programLi Yan Wang
Division of Adolescent and School Health, Centers for Disease Control and Prevention, 4770 Buford Highway, MS K 33, Chamblee, GA 30341, USA
Obes Res 11:1313-24. 2003..To assess the cost-effectiveness and cost-benefit of Planet Health, a school-based intervention designed to reduce obesity in youth of middle-school age children... - Racial differences in infant mortality attributable to birth defects in the United States, 1989-2002Quanhe Yang
National Center on Birth Defects and Developmental Disabilities, Centers for Disease Control and Prevention CDC, Atlanta, Georgia 30333, USA
Birth Defects Res A Clin Mol Teratol 76:706-13. 2006..The objective is to study racial differences in infant mortality attributable to birth defects (IMBD) in the United States... - Cognitive impairment in older Americans in the age of folic acid fortificationRobert J Berry
Am J Clin Nutr 86:265-7; author reply 267-9. 2007