Toni Whistler

Summary

Affiliation: Centers for Disease Control and Prevention
Country: USA

Publications

  1. ncbi request reprint Gene expression correlates of unexplained fatigue
    Toni Whistler
    Centers for Disease Control and Prevention, Viral Exanthems and Herpesvirus Branch, Atlanta, GA 30333, USA
    Pharmacogenomics 7:395-405. 2006
  2. pmc The comparison of different pre- and post-analysis filters for determination of exon-level alternative splicing events using Affymetrix arrays
    Toni Whistler
    Chronic Viral Diseases Branch, Division of Viral and Rickettsial Diseases, Centers for Disease Control and Prevention, Atlanta, Georgia 30329, USA
    J Biomol Tech 21:44-53. 2010
  3. pmc A method for improving SELDI-TOF mass spectrometry data quality
    Toni Whistler
    Chronic Viral Diseases Branch, Centers for Disease Control and Prevention, 1600 Clifton Rd, G41, Atlanta, Georgia, 30329, USA
    Proteome Sci 5:14. 2007
  4. pmc Integrated weighted gene co-expression network analysis with an application to chronic fatigue syndrome
    Angela P Presson
    Biostatistics, University of California, Los Angeles, CA, USA
    BMC Syst Biol 2:95. 2008
  5. pmc Exercise responsive genes measured in peripheral blood of women with chronic fatigue syndrome and matched control subjects
    Toni Whistler
    Viral Exanthems and Herpesvirus Branch, Centers for Disease Control and Prevention, Atlanta, GA 30333, USA
    BMC Physiol 5:5. 2005
  6. pmc Impaired immune function in Gulf War Illness
    Toni Whistler
    Chronic Viral Diseases Branch, Centers for Disease Control and Prevention, Atlanta, GA, USA
    BMC Med Genomics 2:12. 2009
  7. pmc Implementation of exon arrays: alternative splicing during T-cell proliferation as determined by whole genome analysis
    Toni Whistler
    Chronic Viral Diseases Branch, National Center for Emerging and Zoonotic Infectious Diseases proposed, Centers for Disease Control and Prevention, Atlanta GA 30333, USA
    BMC Genomics 11:496. 2010
  8. ncbi request reprint Cell proliferation and inflammation on biopsy samples with multifocal atrophic gastritis before and 1 year after Helicobacter pylori eradication
    Jeannette Guarner
    Infectious Diseases Pathology Activity, National Center for Infectious Diseases, Centers for Disease Control and Prevention, Atlanta, GA 30333, USA
    Arch Pathol Lab Med 129:1451-6. 2005
  9. ncbi request reprint Exploration of statistical dependence between illness parameters using the entropy correlation coefficient
    R Cameron Craddock
    Centers for Disease Control and Prevention, Viral Exanthems and Herpesvirus Branch, Atlanta, GA 30333, USA
    Pharmacogenomics 7:421-8. 2006
  10. pmc Preliminary evidence of mitochondrial dysfunction associated with post-infective fatigue after acute infection with Epstein Barr virus
    Suzanne D Vernon
    Centers for Disease Control and Prevention, Atlanta, Georgia 30333, USA
    BMC Infect Dis 6:15. 2006

Collaborators

Detail Information

Publications19

  1. ncbi request reprint Gene expression correlates of unexplained fatigue
    Toni Whistler
    Centers for Disease Control and Prevention, Viral Exanthems and Herpesvirus Branch, Atlanta, GA 30333, USA
    Pharmacogenomics 7:395-405. 2006
    ..Gene expression correlates of other phenotypic measures in the CFS Computational Challenge (C3) data set could be useful. Future studies of CFS should include as many precise measures of disease phenotype as is practical...
  2. pmc The comparison of different pre- and post-analysis filters for determination of exon-level alternative splicing events using Affymetrix arrays
    Toni Whistler
    Chronic Viral Diseases Branch, Division of Viral and Rickettsial Diseases, Centers for Disease Control and Prevention, Atlanta, Georgia 30329, USA
    J Biomol Tech 21:44-53. 2010
    ..We propose new approaches to data filtration that would reduce the number of technical false-positives and therefore, impact the time spent performing visual inspection of the exon arrays...
  3. pmc A method for improving SELDI-TOF mass spectrometry data quality
    Toni Whistler
    Chronic Viral Diseases Branch, Centers for Disease Control and Prevention, 1600 Clifton Rd, G41, Atlanta, Georgia, 30329, USA
    Proteome Sci 5:14. 2007
    ..However, the events that occur between the first and last sample run are likely to introduce technical variation in the results...
  4. pmc Integrated weighted gene co-expression network analysis with an application to chronic fatigue syndrome
    Angela P Presson
    Biostatistics, University of California, Los Angeles, CA, USA
    BMC Syst Biol 2:95. 2008
    ..Here we show that the additional inclusion of genetic marker data allows one to characterize network relationships as causal or reactive in a chronic fatigue syndrome (CFS) data set...
  5. pmc Exercise responsive genes measured in peripheral blood of women with chronic fatigue syndrome and matched control subjects
    Toni Whistler
    Viral Exanthems and Herpesvirus Branch, Centers for Disease Control and Prevention, Atlanta, GA 30333, USA
    BMC Physiol 5:5. 2005
    ..To search for markers of CFS-associated post-exertional fatigue, we measured peripheral blood gene expression profiles of women with CFS and matched controls before and after exercise challenge...
  6. pmc Impaired immune function in Gulf War Illness
    Toni Whistler
    Chronic Viral Diseases Branch, Centers for Disease Control and Prevention, Atlanta, GA, USA
    BMC Med Genomics 2:12. 2009
    ..Our results do not necessarily elucidate the cause of GWI, but they do reveal a role for immune cell dysfunction in sustaining illness...
  7. pmc Implementation of exon arrays: alternative splicing during T-cell proliferation as determined by whole genome analysis
    Toni Whistler
    Chronic Viral Diseases Branch, National Center for Emerging and Zoonotic Infectious Diseases proposed, Centers for Disease Control and Prevention, Atlanta GA 30333, USA
    BMC Genomics 11:496. 2010
    ..We use this system to examine whole genome transcription and alternate exon usage events that are regulated during lymphocyte proliferation in an attempt to evaluate the exon arrays...
  8. ncbi request reprint Cell proliferation and inflammation on biopsy samples with multifocal atrophic gastritis before and 1 year after Helicobacter pylori eradication
    Jeannette Guarner
    Infectious Diseases Pathology Activity, National Center for Infectious Diseases, Centers for Disease Control and Prevention, Atlanta, GA 30333, USA
    Arch Pathol Lab Med 129:1451-6. 2005
    ..Trial results would be more compelling if cell proliferation and inflammatory markers improved simultaneously with histopathologic lesions...
  9. ncbi request reprint Exploration of statistical dependence between illness parameters using the entropy correlation coefficient
    R Cameron Craddock
    Centers for Disease Control and Prevention, Viral Exanthems and Herpesvirus Branch, Atlanta, GA 30333, USA
    Pharmacogenomics 7:421-8. 2006
    ..Highly related variables are candidates for data reduction, and novel relationships could lead to hypotheses regarding the pathogenesis of CFS...
  10. pmc Preliminary evidence of mitochondrial dysfunction associated with post-infective fatigue after acute infection with Epstein Barr virus
    Suzanne D Vernon
    Centers for Disease Control and Prevention, Atlanta, Georgia 30333, USA
    BMC Infect Dis 6:15. 2006
    ..The objective of this pilot study was to determine the gene expression correlates of post-infective fatigue following acute Epstein Barr virus (EBV) infection...
  11. ncbi request reprint Challenges for molecular profiling of chronic fatigue syndrome
    Suzanne D Vernon
    Center for Infectious Diseases, Division of Viral and Rickettsial Diseases, National Centers for Disease Control and Prevention, Atlanta, GA 30333, USA
    Pharmacogenomics 7:211-8. 2006
    ..Successful molecular profiling of CFS will require the integration of genetic, genomic and proteomic data with environmental and behavioral data to define the heterogeneity in order to optimize intervention...
  12. doi request reprint Impact of acute psychosocial stress on peripheral blood gene expression pathways in healthy men
    Urs M Nater
    Chronic Viral Diseases Branch, National Center for Zoonotic, Vector Borne and Enteric Diseases, Centers for Disease Control and Prevention, 1600 Clifton Rd, MS G41, Atlanta, GA 30329, USA
    Biol Psychol 82:125-32. 2009
    ..These results have relevance for understanding molecular mechanisms of the physiological stress response, and might be used to further study adverse health outcomes of psychosocial stress...
  13. pmc Comparison of target labeling methods for use with Affymetrix GeneChips
    William Lonergan
    Chronic Viral Diseases Branch, Division of Viral and Rickettsial Diseases, Centers for Disease Control and Prevention, Atlanta, GA 30329, USA
    BMC Biotechnol 7:24. 2007
    ....
  14. ncbi request reprint Two optimized combination assays to examine apoptosis pathways in clinical samples
    Mark Hollier
    Chronic Viral Diseases Branch, Division of Viral and Rickettsial Diseases, Centers for Disease Control and Prevention, Atlanta, Georgia 30329, USA
    Cytometry A 71:675-85. 2007
    ..This hinders studies on clinical samples that have limited cell numbers. Our objective was to combine and optimize assays that target specific stages of apoptosis for use in a typical clinical blood sample...
  15. ncbi request reprint Microarray technology for use in molecular epidemiology
    Suzanne D Vernon
    Division of Viral and Rickettsial Diseases, National Centers for Infectious Diseases, Center for Disease Control and Prevention, Atlanta, GA, USA
    Methods Mol Biol 382:97-113. 2007
    ..This reproducible and reliable approach for using microarrays should be applicable to any biological questions asked...
  16. ncbi request reprint Correlation of psycho-neuroendocrine-immune (PNI) gene expression with symptoms of acute infectious mononucleosis
    Suzanne D Vernon
    Viral Exanthems and Herpesvirus Branch, National Center for Infectious Diseases, Centers for Disease Control and Prevention, 1600 Clifton Road MSA15, Atlanta, GA 30333, USA
    Brain Res 1068:1-6. 2006
    ..Thus, investigation of the PNI response in peripheral blood may provide novel insights into the complex pathophysiology of centrally mediated disease states...
  17. pmc Identification of Phosphoglycerate Kinase 1 (PGK1) as a reference gene for quantitative gene expression measurements in human blood RNA
    Virginia R Falkenberg
    Division of High Consequence Pathogens and Pathology, Centers for Disease Control and Prevention, Atlanta, GA, 30333, USA
    BMC Res Notes 4:324. 2011
    ..abstract:..
  18. pmc Convergent genomic studies identify association of GRIK2 and NPAS2 with chronic fatigue syndrome
    Alicia K Smith
    Division of High Consequence Pathogens and Pathology, Centers for Disease Control and Prevention, Atlanta, GA 30333, USA
    Neuropsychobiology 64:183-94. 2011
    ....
  19. ncbi request reprint Can pre-neoplastic lesions be detected in gastric biopsies of children with Helicobacter pylori infection?
    Jeannette Guarner
    Infectious Disease Pathology Activity, National Center for Infectious Diseases, Centers for Disease Control and Prevention, Atlanta GA 30333, USA
    J Pediatr Gastroenterol Nutr 37:309-14. 2003
    ..Active gastritis, gastric mucosal atrophy and intestinal metaplasia are lesions associated with Helicobacter pylori infection. Atrophy and intestinal metaplasia are only seen in adults...