Xin Wang

Summary

Affiliation: Centers for Disease Control and Prevention
Country: USA

Publications

  1. doi request reprint Detection of bacterial pathogens in Mongolia meningitis surveillance with a new real-time PCR assay to detect Haemophilus influenzae
    Xin Wang
    Meningitis and Vaccine Preventable Diseases Branch, Division of Bacterial Diseases, National Center of Immunization and Respiratory Diseases, Centers for Disease Control and Prevention, Atlanta, GA 30333, USA
    Int J Med Microbiol 301:303-9. 2011
  2. pmc Clinical validation of multiplex real-time PCR assays for detection of bacterial meningitis pathogens
    Xin Wang
    Division of Bacterial Diseases, Centers for Disease Control and Prevention, Atlanta, Georgia, USA
    J Clin Microbiol 50:702-8. 2012
  3. pmc Evaluation of new biomarker genes for differentiating Haemophilus influenzae from Haemophilus haemolyticus
    M Jordan Theodore
    Meningitis and Vaccine Preventable Diseases Branch, Centers for Disease Control and Prevention CDC, Atlanta, Georgia, USA
    J Clin Microbiol 50:1422-4. 2012
  4. pmc Using single-nucleotide polymorphisms to discriminate disease-associated from carried genomes of Neisseria meningitidis
    Lee S Katz
    School of Biology, Georgia Institute of Technology, Atlanta, GA 30332, USA
    J Bacteriol 193:3633-41. 2011
  5. doi request reprint Absence of high molecular weight proteins 1 and/or 2 is associated with decreased adherence among non-typeable Haemophilus influenzae clinical isolates
    Jeni Vuong
    1Meningitis and Vaccine Preventable Diseases Branch, Division of Bacterial Diseases, Centers for Disease Control and Prevention, Atlanta, GA 30333, USA
    J Med Microbiol 62:1649-56. 2013
  6. pmc sodC-based real-time PCR for detection of Neisseria meningitidis
    Jennifer Dolan Thomas
    Meningitis and Vaccine Preventable Diseases Branch, Division of Bacterial Diseases, National Center for Immunization and Respiratory Diseases, Centers for Disease Control and Prevention, Atlanta, Georgia, United States of America
    PLoS ONE 6:e19361. 2011
  7. doi request reprint Prevalence and genetic diversity of candidate vaccine antigens among invasive Neisseria meningitidis isolates in the United States
    Xin Wang
    Meningitis and Vaccine Preventable Disease Branch, Division of Bacterial Diseases, National Center of Immunization and Respiratory Diseases, Centers for Disease Control and Prevention, Atlanta, GA 30333, United States
    Vaccine 29:4739-44. 2011
  8. pmc Haemophilus haemolyticus isolates causing clinical disease
    Raydel Anderson
    Meningitis and Vaccine Preventable Disease Branch, Division of Bacterial Diseases, National Center for Infectious and Respiratory Diseases, Centers for Disease Control and Prevention, Atlanta, Georgia, USA
    J Clin Microbiol 50:2462-5. 2012
  9. ncbi request reprint Emergence of ciprofloxacin-resistant Neisseria meningitidis in North America
    Henry M Wu
    Office of Workforce and Career Development, and the Division of Bacterial Diseases, National Center for Immunization and Respiratory Diseases, Centers for Disease Control and Prevention, Atlanta, GA 30333, USA
    N Engl J Med 360:886-92. 2009
  10. doi request reprint Prolonged university outbreak of meningococcal disease associated with a serogroup B strain rarely seen in the United States
    Sema Mandal
    Meningitis and Vaccine Preventable Diseases Branch, Division of Bacterial Diseases, National Center for Immunization and Respiratory Diseases, Centers for Disease Control and Prevention, 1600 Clifton Rd NE, MS C 25, Atlanta, GA 30329, USA
    Clin Infect Dis 57:344-8. 2013

Collaborators

Detail Information

Publications11

  1. doi request reprint Detection of bacterial pathogens in Mongolia meningitis surveillance with a new real-time PCR assay to detect Haemophilus influenzae
    Xin Wang
    Meningitis and Vaccine Preventable Diseases Branch, Division of Bacterial Diseases, National Center of Immunization and Respiratory Diseases, Centers for Disease Control and Prevention, Atlanta, GA 30333, USA
    Int J Med Microbiol 301:303-9. 2011
    ..A sensitive rt-PCR assay to detect both typeable and non-typeable Hi is a useful tool for improving Hi disease surveillance especially after Hib vaccine introduction...
  2. pmc Clinical validation of multiplex real-time PCR assays for detection of bacterial meningitis pathogens
    Xin Wang
    Division of Bacterial Diseases, Centers for Disease Control and Prevention, Atlanta, Georgia, USA
    J Clin Microbiol 50:702-8. 2012
    ..There were no substantial differences in sensitivity and specificity between these multiplex and singleplex real-time PCR assays...
  3. pmc Evaluation of new biomarker genes for differentiating Haemophilus influenzae from Haemophilus haemolyticus
    M Jordan Theodore
    Meningitis and Vaccine Preventable Diseases Branch, Centers for Disease Control and Prevention CDC, Atlanta, Georgia, USA
    J Clin Microbiol 50:1422-4. 2012
    ..haemolyticus. Phylogenetic analysis using the 16S rRNA gene demonstrated two distinct groups for H. influenzae and H. haemolyticus...
  4. pmc Using single-nucleotide polymorphisms to discriminate disease-associated from carried genomes of Neisseria meningitidis
    Lee S Katz
    School of Biology, Georgia Institute of Technology, Atlanta, GA 30332, USA
    J Bacteriol 193:3633-41. 2011
    ..A number of overrepresented functional categories related to virulence were uncovered among SNP-associated genes, including genes related to the category "symbiosis, encompassing mutualism through parasitism."..
  5. doi request reprint Absence of high molecular weight proteins 1 and/or 2 is associated with decreased adherence among non-typeable Haemophilus influenzae clinical isolates
    Jeni Vuong
    1Meningitis and Vaccine Preventable Diseases Branch, Division of Bacterial Diseases, Centers for Disease Control and Prevention, Atlanta, GA 30333, USA
    J Med Microbiol 62:1649-56. 2013
    ..Among the high-adherence isolates (nā€Š=ā€Š69), 72ā€Š% reacted with 3D6 and 21ā€Š% with 10C5. Our data indicate that the absence of Hmw1 and/or Hmw2 was associated with decreased adherence to D562 cells. ..
  6. pmc sodC-based real-time PCR for detection of Neisseria meningitidis
    Jennifer Dolan Thomas
    Meningitis and Vaccine Preventable Diseases Branch, Division of Bacterial Diseases, National Center for Immunization and Respiratory Diseases, Centers for Disease Control and Prevention, Atlanta, Georgia, United States of America
    PLoS ONE 6:e19361. 2011
    ..This sodC rt-PCR assay is a highly sensitive and specific method for detection of Nm, especially in carriage studies where many meningococcal isolates lack capsule genes...
  7. doi request reprint Prevalence and genetic diversity of candidate vaccine antigens among invasive Neisseria meningitidis isolates in the United States
    Xin Wang
    Meningitis and Vaccine Preventable Disease Branch, Division of Bacterial Diseases, National Center of Immunization and Respiratory Diseases, Centers for Disease Control and Prevention, Atlanta, GA 30333, United States
    Vaccine 29:4739-44. 2011
    ....
  8. pmc Haemophilus haemolyticus isolates causing clinical disease
    Raydel Anderson
    Meningitis and Vaccine Preventable Disease Branch, Division of Bacterial Diseases, National Center for Infectious and Respiratory Diseases, Centers for Disease Control and Prevention, Atlanta, Georgia, USA
    J Clin Microbiol 50:2462-5. 2012
    ..All cases had different symptoms and presentations. Our study suggests that a testing scheme that includes reliable PCR assays and standard microbiological methods should be used in order to improve H. haemolyticus identification...
  9. ncbi request reprint Emergence of ciprofloxacin-resistant Neisseria meningitidis in North America
    Henry M Wu
    Office of Workforce and Career Development, and the Division of Bacterial Diseases, National Center for Immunization and Respiratory Diseases, Centers for Disease Control and Prevention, Atlanta, GA 30333, USA
    N Engl J Med 360:886-92. 2009
    ..Ciprofloxacin-resistant N. meningitidis has emerged in North America...
  10. doi request reprint Prolonged university outbreak of meningococcal disease associated with a serogroup B strain rarely seen in the United States
    Sema Mandal
    Meningitis and Vaccine Preventable Diseases Branch, Division of Bacterial Diseases, National Center for Immunization and Respiratory Diseases, Centers for Disease Control and Prevention, 1600 Clifton Rd NE, MS C 25, Atlanta, GA 30329, USA
    Clin Infect Dis 57:344-8. 2013
    ..Unlike that for serogroups prevented by quadrivalent meningococcal vaccines, public health response to outbreaks of serogroup B meningococcal disease is limited by lack of a US licensed vaccine...
  11. pmc Meningococcus genome informatics platform: a system for analyzing multilocus sequence typing data
    Lee S Katz
    School of Biology, Georgia Institute of Technology, Atlanta, GA 30332, USA
    Nucleic Acids Res 37:W606-11. 2009
    ....