Suzanne D Vernon

Summary

Affiliation: Centers for Disease Control and Prevention
Country: USA

Publications

  1. ncbi request reprint Correlation of psycho-neuroendocrine-immune (PNI) gene expression with symptoms of acute infectious mononucleosis
    Suzanne D Vernon
    Viral Exanthems and Herpesvirus Branch, National Center for Infectious Diseases, Centers for Disease Control and Prevention, 1600 Clifton Road MSA15, Atlanta, GA 30333, USA
    Brain Res 1068:1-6. 2006
  2. ncbi request reprint Microarray technology for use in molecular epidemiology
    Suzanne D Vernon
    Division of Viral and Rickettsial Diseases, National Centers for Infectious Diseases, Center for Disease Control and Prevention, Atlanta, GA, USA
    Methods Mol Biol 382:97-113. 2007
  3. ncbi request reprint Challenges for molecular profiling of chronic fatigue syndrome
    Suzanne D Vernon
    Center for Infectious Diseases, Division of Viral and Rickettsial Diseases, National Centers for Disease Control and Prevention, Atlanta, GA 30333, USA
    Pharmacogenomics 7:211-8. 2006
  4. pmc Analysis of 16S rRNA gene sequences and circulating cell-free DNA from plasma of chronic fatigue syndrome and non-fatigued subjects
    Suzanne D Vernon
    Division of Viral and Rickettsial Diseases, National Center for Infectious Diseases, Centers for Disease Control and Prevention, Atlanta, GA 30333, USA
    BMC Microbiol 2:39. 2002
  5. pmc Utility of the blood for gene expression profiling and biomarker discovery in chronic fatigue syndrome
    Suzanne D Vernon
    Division of Viral and Rickettsial Diseases, National Center for Infectious Diseases, Centers for Disease Control and Prevention, 1600 Clifton Road, Atlanta, GA 30333, USA
    Dis Markers 18:193-9. 2002
  6. pmc Bioelectronic DNA detection of human papillomaviruses using eSensor: a model system for detection of multiple pathogens
    Suzanne D Vernon
    Division of Viral and Rickettsial Diseases, National Center for Infectious Diseases, Centers for Disease Control and Prevention, Atlanta, Georgia 30333, USA
    BMC Infect Dis 3:12. 2003
  7. pmc Preliminary evidence of mitochondrial dysfunction associated with post-infective fatigue after acute infection with Epstein Barr virus
    Suzanne D Vernon
    Centers for Disease Control and Prevention, Atlanta, Georgia 30333, USA
    BMC Infect Dis 6:15. 2006
  8. ncbi request reprint Evaluation of RNA markers for early detection of cervical neoplasia in exfoliated cervical cells
    Martin Steinau
    Division of Viral and Rickettsial Disease, Viral Exanthems and Herpesvirus Branch, Centers for Disease Control and Prevention, 1600 Clifton Road, MS G 41, Atlanta, GA 30333, USA
    Cancer Epidemiol Biomarkers Prev 16:295-301. 2007
  9. pmc Gene expression profile of cervical tissue compared to exfoliated cells: impact on biomarker discovery
    Martin Steinau
    Centers for Disease Control and Prevention, Atlanta, GA, USA
    BMC Genomics 6:64. 2005
  10. ncbi request reprint Epidemiologic and viral factors associated with cervical neoplasia in HPV-16-positive women
    Mangalathu S Rajeevan
    Centers for Disease Control and Prevention, Atlanta, GA 30333, USA
    Int J Cancer 115:114-20. 2005

Detail Information

Publications35

  1. ncbi request reprint Correlation of psycho-neuroendocrine-immune (PNI) gene expression with symptoms of acute infectious mononucleosis
    Suzanne D Vernon
    Viral Exanthems and Herpesvirus Branch, National Center for Infectious Diseases, Centers for Disease Control and Prevention, 1600 Clifton Road MSA15, Atlanta, GA 30333, USA
    Brain Res 1068:1-6. 2006
    ..Thus, investigation of the PNI response in peripheral blood may provide novel insights into the complex pathophysiology of centrally mediated disease states...
  2. ncbi request reprint Microarray technology for use in molecular epidemiology
    Suzanne D Vernon
    Division of Viral and Rickettsial Diseases, National Centers for Infectious Diseases, Center for Disease Control and Prevention, Atlanta, GA, USA
    Methods Mol Biol 382:97-113. 2007
    ..This reproducible and reliable approach for using microarrays should be applicable to any biological questions asked...
  3. ncbi request reprint Challenges for molecular profiling of chronic fatigue syndrome
    Suzanne D Vernon
    Center for Infectious Diseases, Division of Viral and Rickettsial Diseases, National Centers for Disease Control and Prevention, Atlanta, GA 30333, USA
    Pharmacogenomics 7:211-8. 2006
    ..Successful molecular profiling of CFS will require the integration of genetic, genomic and proteomic data with environmental and behavioral data to define the heterogeneity in order to optimize intervention...
  4. pmc Analysis of 16S rRNA gene sequences and circulating cell-free DNA from plasma of chronic fatigue syndrome and non-fatigued subjects
    Suzanne D Vernon
    Division of Viral and Rickettsial Diseases, National Center for Infectious Diseases, Centers for Disease Control and Prevention, Atlanta, GA 30333, USA
    BMC Microbiol 2:39. 2002
    ..Plasma DNA from 34 CFS and 55 non-fatigued subjects was assessed to determine plasma DNA concentration and the presence of bacterial 16S ribosomal DNA (rDNA) sequences...
  5. pmc Utility of the blood for gene expression profiling and biomarker discovery in chronic fatigue syndrome
    Suzanne D Vernon
    Division of Viral and Rickettsial Diseases, National Center for Infectious Diseases, Centers for Disease Control and Prevention, 1600 Clifton Road, Atlanta, GA 30333, USA
    Dis Markers 18:193-9. 2002
    ..These results successfully demonstrate the utility of the blood for gene expression profiling to distinguish subjects with CFS from healthy controls and for identifying genes that could serve as CFS biomarkers...
  6. pmc Bioelectronic DNA detection of human papillomaviruses using eSensor: a model system for detection of multiple pathogens
    Suzanne D Vernon
    Division of Viral and Rickettsial Diseases, National Center for Infectious Diseases, Centers for Disease Control and Prevention, Atlanta, Georgia 30333, USA
    BMC Infect Dis 3:12. 2003
    ..We used human papillomaviruses (HPV) as a model system to evaluate the utility of a nucleic acid, hybridization-based bioelectronic DNA detection platform (eSensor) in identifying multiple pathogens...
  7. pmc Preliminary evidence of mitochondrial dysfunction associated with post-infective fatigue after acute infection with Epstein Barr virus
    Suzanne D Vernon
    Centers for Disease Control and Prevention, Atlanta, Georgia 30333, USA
    BMC Infect Dis 6:15. 2006
    ..The objective of this pilot study was to determine the gene expression correlates of post-infective fatigue following acute Epstein Barr virus (EBV) infection...
  8. ncbi request reprint Evaluation of RNA markers for early detection of cervical neoplasia in exfoliated cervical cells
    Martin Steinau
    Division of Viral and Rickettsial Disease, Viral Exanthems and Herpesvirus Branch, Centers for Disease Control and Prevention, 1600 Clifton Road, MS G 41, Atlanta, GA 30333, USA
    Cancer Epidemiol Biomarkers Prev 16:295-301. 2007
    ....
  9. pmc Gene expression profile of cervical tissue compared to exfoliated cells: impact on biomarker discovery
    Martin Steinau
    Centers for Disease Control and Prevention, Atlanta, GA, USA
    BMC Genomics 6:64. 2005
    ..However, because of keratinization and terminal differentiation it is not clear that these cells have an mRNA profile representative of cervical tissue, and that the profile can distinguish the lesions targeted for early detection...
  10. ncbi request reprint Epidemiologic and viral factors associated with cervical neoplasia in HPV-16-positive women
    Mangalathu S Rajeevan
    Centers for Disease Control and Prevention, Atlanta, GA 30333, USA
    Int J Cancer 115:114-20. 2005
    ..Cellular proliferation and differentiation pathways affected by HPV should be investigated as biomarkers for cervical cancer screening...
  11. ncbi request reprint Gene expression profiling of dysplastic differentiation in cervical epithelial cells harboring human papillomavirus 16
    Daya G Ranamukhaarachchi
    Division of Viral and Rickettsial Diseases, National Center for Infectious Diseases, Centers for Disease Control and Prevention, Public Health Service US DHHS, Atlanta, GA 30333, USA
    Genomics 85:727-38. 2005
    ..Some of the genes with altered expression identified in this model of dysplastic differentiation may be useful biomarkers for early detection of cervical neoplasia and other HPV-associated oropharyngeal and anogenital cancers...
  12. doi request reprint Impact of acute psychosocial stress on peripheral blood gene expression pathways in healthy men
    Urs M Nater
    Chronic Viral Diseases Branch, National Center for Zoonotic, Vector Borne and Enteric Diseases, Centers for Disease Control and Prevention, 1600 Clifton Rd, MS G41, Atlanta, GA 30329, USA
    Biol Psychol 82:125-32. 2009
    ..These results have relevance for understanding molecular mechanisms of the physiological stress response, and might be used to further study adverse health outcomes of psychosocial stress...
  13. ncbi request reprint Genetic evaluation of the serotonergic system in chronic fatigue syndrome
    Alicia K Smith
    Division of Viral and Rickettsial Diseases, National Center for Infectious Diseases, Centers for Disease Control and Prevention, 1600 Clifton Road, MSG41, Atlanta, GA 30333, USA
    Psychoneuroendocrinology 33:188-97. 2008
    ..These data indicate that sequence variation in HTR2A, potentially resulting in its enhanced activity, may be involved in the pathophysiology of CFS...
  14. ncbi request reprint The challenge of integrating disparate high-content data: epidemiological, clinical and laboratory data collected during an in-hospital study of chronic fatigue syndrome
    Suzanne D Vernon
    Centers for Disease Control and Prevention, National Center for Infectious Diseases, Atlanta, GA, USA
    Pharmacogenomics 7:345-54. 2006
    ....
  15. ncbi request reprint Global amplification of sense RNA: a novel method to replicate and archive mRNA for gene expression analysis
    Mangalathu S Rajeevan
    Viral Exanthems and Herpesvirus Branch, Division of Viral and Rickettsial Diseases, National Center for Infectious Diseases, Centers for Disease Control and Prevention, US Department of Health and Human Services, Atlanta, GA 30333, USA
    Genomics 82:491-7. 2003
    ..00001-0.1%). This reflects the high fidelity of sRNA synthesis for mRNA as low as 0.3 copies/cell. sRNA is amplified synthetic mRNA in the 5'-->3' direction; the appropriate template for any gene expression analysis...
  16. pmc Identification of ambiguities in the 1994 chronic fatigue syndrome research case definition and recommendations for resolution
    William C Reeves
    Centers for Disease Control and Prevention, Atlanta, Georgia, United States of America
    BMC Health Serv Res 3:25. 2003
    ..Difficulties with accurate case ascertainment contribute to this ignorance...
  17. pmc Chronic fatigue syndrome--a clinically empirical approach to its definition and study
    William C Reeves
    Division of Viral and Rickettsial Diseases, Centers for Disease Control and Prevention, Atlanta, GA, USA
    BMC Med 3:19. 2005
    ..The lack of standardized criteria for defining chronic fatigue syndrome (CFS) has constrained research. The objective of this study was to apply the 1994 CFS criteria by standardized reproducible criteria...
  18. pmc Exercise responsive genes measured in peripheral blood of women with chronic fatigue syndrome and matched control subjects
    Toni Whistler
    Viral Exanthems and Herpesvirus Branch, Centers for Disease Control and Prevention, Atlanta, GA 30333, USA
    BMC Physiol 5:5. 2005
    ..To search for markers of CFS-associated post-exertional fatigue, we measured peripheral blood gene expression profiles of women with CFS and matched controls before and after exercise challenge...
  19. pmc Molecular markers for early detection of cervical neoplasia
    Elizabeth R Unger
    Division of Viral and Rickettsial Diseases, National Center for Infectious Diseases, Centers for Disease Control and Prevention, Public Health Service, US Department of Health and Human Services, Atlanta, GA 30333, USA
    Dis Markers 20:103-16. 2004
  20. ncbi request reprint Exploration of neuroendocrine and immune gene expression in peripheral blood mononuclear cells
    Ainsley C Nicholson
    Division of Viral and Rickettsial Diseases, National Center for Infectious Diseases, Centers for Disease Control and Prevention, 1600 Clifton Road, Atlanta, GA 30333, USA
    Brain Res Mol Brain Res 129:193-7. 2004
    ....
  21. ncbi request reprint Differential-display PCR of peripheral blood for biomarker discovery in chronic fatigue syndrome
    Martin Steinau
    Division of Viral and Rickettsial Diseases, National Center for Infectious Diseases, Centers for Disease Control and Prevention, 1600 Clifton Rd, MSG 41, Atlanta, GA 30333, USA
    J Mol Med (Berl) 82:750-5. 2004
    ..The real-time reverse-transcription PCR assays that we developed for assay of these biomarkers will facilitate high-throughput testing of these additional samples...
  22. pmc Transcriptional control of complement activation in an exercise model of chronic fatigue syndrome
    Bristol Sorensen
    Division of Viral and Rickettsial Diseases, National Center for Zoonotic, Vector Borne, and Enteric Diseases, Centers for Disease Control and Prevention, Atlanta, Georgia 30333, United States of America
    Mol Med 15:34-42. 2009
    ..MASP2 down-regulation may act as an antiinflammatory acute-phase response in healthy subjects, whereas its elevated level may account for increased C4a and inflammation-mediated postexertional malaise in CFS subjects...
  23. ncbi request reprint Molecular quality of exfoliated cervical cells: implications for molecular epidemiology and biomarker discovery
    Angelique H Habis
    Centers for Disease Control and Prevention, U S Public Health Service, U S Department of Health and Human Services, Atlanta, GA, USA
    Cancer Epidemiol Biomarkers Prev 13:492-6. 2004
    ..However, with a sensitive gold particle-based detection method, reproducible microarray results were obtained using this RNA...
  24. pmc Inclusion of the glucocorticoid receptor in a hypothalamic pituitary adrenal axis model reveals bistability
    Shakti Gupta
    Division of Viral and Rickettsial Diseases, National Center for Zoonotic, Vector Borne, and Enteric Diseases, Centers for Disease Control and Prevention, Atlanta, Georgia 30333, USA
    Theor Biol Med Model 4:8. 2007
    ..The HPA axis responds to physical and mental challenge to maintain homeostasis in part by controlling the body's cortisol level. Dysregulation of the HPA axis is implicated in numerous stress-related diseases...
  25. pmc Comparison of target labeling methods for use with Affymetrix GeneChips
    William Lonergan
    Chronic Viral Diseases Branch, Division of Viral and Rickettsial Diseases, Centers for Disease Control and Prevention, Atlanta, GA 30329, USA
    BMC Biotechnol 7:24. 2007
    ....
  26. ncbi request reprint Two optimized combination assays to examine apoptosis pathways in clinical samples
    Mark Hollier
    Chronic Viral Diseases Branch, Division of Viral and Rickettsial Diseases, Centers for Disease Control and Prevention, Atlanta, Georgia 30329, USA
    Cytometry A 71:675-85. 2007
    ..This hinders studies on clinical samples that have limited cell numbers. Our objective was to combine and optimize assays that target specific stages of apoptosis for use in a typical clinical blood sample...
  27. pmc Assessment of normal variability in peripheral blood gene expression
    Catherine Campbell
    Division of Viral and Rickettsial Diseases, National Center for Infectious Diseases, Centers for Disease Control and Prevention, 1600 Clifton Road, Atlanta, GA 30333, USA
    Dis Markers 18:201-6. 2002
    ..These results suggest that observed variation was due to experimental variability...
  28. ncbi request reprint Molecular characterization of human papillomaviruses by PCR and in situ hybridization
    Suzanne D Vernon
    Centers of Disease Control and Prevention, Atlanta, GA, USA
    Methods Mol Med 97:159-80. 2004
  29. pmc Impaired immune function in Gulf War Illness
    Toni Whistler
    Chronic Viral Diseases Branch, Centers for Disease Control and Prevention, Atlanta, GA, USA
    BMC Med Genomics 2:12. 2009
    ..Our results do not necessarily elucidate the cause of GWI, but they do reveal a role for immune cell dysfunction in sustaining illness...
  30. pmc Live sequence charts to model medical information
    Eric Aslakson
    Poiema, LLC, 375 Chelsea Cir NE, Atlanta, GA 30307, USA
    Theor Biol Med Model 9:22. 2012
    ..The purpose of this study was to develop an object modeling technique as a first step towards a formal database of medical records...
  31. pmc A method for improving SELDI-TOF mass spectrometry data quality
    Toni Whistler
    Chronic Viral Diseases Branch, Centers for Disease Control and Prevention, 1600 Clifton Rd, G41, Atlanta, Georgia, 30329, USA
    Proteome Sci 5:14. 2007
    ..However, the events that occur between the first and last sample run are likely to introduce technical variation in the results...
  32. ncbi request reprint Modifying differential display polymerase chain reaction to detect relative changes in gene expression profiles
    Daya G Ranamukhaarachchi
    Viral Exanthems and Herpesvirus Branch, Division of Viral and Rickettsial Diseases, National Center for Infectious Diseases, Centers for Disease Control and Prevention, U S Department of Health and Human Services, Atlanta, GA 30333, USA
    Anal Biochem 306:343-6. 2002
  33. pmc Post-infective and chronic fatigue syndromes precipitated by viral and non-viral pathogens: prospective cohort study
    Ian Hickie
    Brain and Mind Research Institute, Sydney University, Sydney, NSW 2050, Australia
    BMJ 333:575. 2006
    ..To delineate the risk factors, symptom patterns, and longitudinal course of prolonged illnesses after a variety of acute infections...
  34. ncbi request reprint Impact of RNA extraction from limited samples on microarray results
    Hanna Ojaniemi
    Karolinska Institutet at Huddinge University Hospital, Royal Institute of Technology, Stockholm, Sweden
    Biotechniques 35:968-73. 2003
    ..These experiments illustrate that microarray technology holds great promise for the use of limited clinical samples in the diagnostic setting...
  35. ncbi request reprint Absence of Mycoplasma species DNA in chronic fatigue syndrome
    Suzanne D Vernon
    J Med Microbiol 52:1027-8. 2003