E R Unger

Summary

Affiliation: Centers for Disease Control and Prevention
Country: USA

Publications

  1. pmc A pilot registry of unexplained fatiguing illnesses and chronic fatigue syndrome
    Dana J Brimmer
    Division of High Consequence Pathogens and Pathology, Centers for Disease Control and Prevention, 1600 Clifton Road, MS G41, Atlanta, GA 30033, USA
    BMC Res Notes 6:309. 2013
  2. pmc A population-based study of the clinical course of chronic fatigue syndrome
    Rosane Nisenbaum
    Division of Viral and Rickettsial Diseases, National Center for Infectious Diseases, Centers for Disease Control and Prevention, Atlanta, Georgia, USA
    Health Qual Life Outcomes 1:49. 2003
  3. pmc Exercise responsive genes measured in peripheral blood of women with chronic fatigue syndrome and matched control subjects
    Toni Whistler
    Viral Exanthems and Herpesvirus Branch, Centers for Disease Control and Prevention, Atlanta, GA 30333, USA
    BMC Physiol 5:5. 2005
  4. pmc Sleep characteristics of persons with chronic fatigue syndrome and non-fatigued controls: results from a population-based study
    William C Reeves
    Viral Exanthems and Herpesvirus Branch, Division of Viral and Rickettsial Diseases, National Center for Infectious Diseases, Centers for Disease Control and Prevention, Atlanta, GA, USA
    BMC Neurol 6:41. 2006
  5. pmc Perception versus polysomnographic assessment of sleep in CFS and non-fatigued control subjects: results from a population-based study
    Matthias Majer
    Department of Psychiatry and Behavioral Sciences, Emory University School of Medicine, Atlanta, USA
    BMC Neurol 7:40. 2007
  6. pmc Analysis of 16S rRNA gene sequences and circulating cell-free DNA from plasma of chronic fatigue syndrome and non-fatigued subjects
    Suzanne D Vernon
    Division of Viral and Rickettsial Diseases, National Center for Infectious Diseases, Centers for Disease Control and Prevention, Atlanta, GA 30333, USA
    BMC Microbiol 2:39. 2002
  7. pmc An evaluation of exclusionary medical/psychiatric conditions in the definition of chronic fatigue syndrome
    James F Jones
    Chronic Viral Diseases Branch, Coordinating Center for Infectious Diseases, Centers for Disease Control and Prevention, 1600 Clifton Road, MS A15, Atlanta, GA 30333, USA
    BMC Med 7:57. 2009
  8. pmc Chronic fatigue syndrome--a clinically empirical approach to its definition and study
    William C Reeves
    Division of Viral and Rickettsial Diseases, Centers for Disease Control and Prevention, Atlanta, GA, USA
    BMC Med 3:19. 2005
  9. pmc Bioelectronic DNA detection of human papillomaviruses using eSensor: a model system for detection of multiple pathogens
    Suzanne D Vernon
    Division of Viral and Rickettsial Diseases, National Center for Infectious Diseases, Centers for Disease Control and Prevention, Atlanta, Georgia 30333, USA
    BMC Infect Dis 3:12. 2003
  10. pmc Assessing the relationship between HIV infection and cervical cancer in Côte d'Ivoire: a case-control study
    Georgette Adjorlolo-Johnson
    Projet RETRO CI, Centers for Disease Control and Prevention, Global HIV AIDS Program, Abidjan, Cote d Ivoire
    BMC Infect Dis 10:242. 2010

Detail Information

Publications76

  1. pmc A pilot registry of unexplained fatiguing illnesses and chronic fatigue syndrome
    Dana J Brimmer
    Division of High Consequence Pathogens and Pathology, Centers for Disease Control and Prevention, 1600 Clifton Road, MS G41, Atlanta, GA 30033, USA
    BMC Res Notes 6:309. 2013
    ..If patients met registry criteria, they were invited to a one-day clinic for physical and laboratory evaluations. We classified patients based on the 1994 case definition...
  2. pmc A population-based study of the clinical course of chronic fatigue syndrome
    Rosane Nisenbaum
    Division of Viral and Rickettsial Diseases, National Center for Infectious Diseases, Centers for Disease Control and Prevention, Atlanta, Georgia, USA
    Health Qual Life Outcomes 1:49. 2003
    ..We conducted a longitudinal population-based study to characterize the clinical course of CFS...
  3. pmc Exercise responsive genes measured in peripheral blood of women with chronic fatigue syndrome and matched control subjects
    Toni Whistler
    Viral Exanthems and Herpesvirus Branch, Centers for Disease Control and Prevention, Atlanta, GA 30333, USA
    BMC Physiol 5:5. 2005
    ..To search for markers of CFS-associated post-exertional fatigue, we measured peripheral blood gene expression profiles of women with CFS and matched controls before and after exercise challenge...
  4. pmc Sleep characteristics of persons with chronic fatigue syndrome and non-fatigued controls: results from a population-based study
    William C Reeves
    Viral Exanthems and Herpesvirus Branch, Division of Viral and Rickettsial Diseases, National Center for Infectious Diseases, Centers for Disease Control and Prevention, Atlanta, GA, USA
    BMC Neurol 6:41. 2006
    ....
  5. pmc Perception versus polysomnographic assessment of sleep in CFS and non-fatigued control subjects: results from a population-based study
    Matthias Majer
    Department of Psychiatry and Behavioral Sciences, Emory University School of Medicine, Atlanta, USA
    BMC Neurol 7:40. 2007
    ..We conducted this study to determine whether alterations in objective sleep characteristics are associated with subjective measures of poor sleep quality in persons with CFS...
  6. pmc Analysis of 16S rRNA gene sequences and circulating cell-free DNA from plasma of chronic fatigue syndrome and non-fatigued subjects
    Suzanne D Vernon
    Division of Viral and Rickettsial Diseases, National Center for Infectious Diseases, Centers for Disease Control and Prevention, Atlanta, GA 30333, USA
    BMC Microbiol 2:39. 2002
    ..Plasma DNA from 34 CFS and 55 non-fatigued subjects was assessed to determine plasma DNA concentration and the presence of bacterial 16S ribosomal DNA (rDNA) sequences...
  7. pmc An evaluation of exclusionary medical/psychiatric conditions in the definition of chronic fatigue syndrome
    James F Jones
    Chronic Viral Diseases Branch, Coordinating Center for Infectious Diseases, Centers for Disease Control and Prevention, 1600 Clifton Road, MS A15, Atlanta, GA 30333, USA
    BMC Med 7:57. 2009
    ..This study compares illness parameters between individuals with CFS who have and those who do not have exclusionary conditions...
  8. pmc Chronic fatigue syndrome--a clinically empirical approach to its definition and study
    William C Reeves
    Division of Viral and Rickettsial Diseases, Centers for Disease Control and Prevention, Atlanta, GA, USA
    BMC Med 3:19. 2005
    ..The lack of standardized criteria for defining chronic fatigue syndrome (CFS) has constrained research. The objective of this study was to apply the 1994 CFS criteria by standardized reproducible criteria...
  9. pmc Bioelectronic DNA detection of human papillomaviruses using eSensor: a model system for detection of multiple pathogens
    Suzanne D Vernon
    Division of Viral and Rickettsial Diseases, National Center for Infectious Diseases, Centers for Disease Control and Prevention, Atlanta, Georgia 30333, USA
    BMC Infect Dis 3:12. 2003
    ..We used human papillomaviruses (HPV) as a model system to evaluate the utility of a nucleic acid, hybridization-based bioelectronic DNA detection platform (eSensor) in identifying multiple pathogens...
  10. pmc Assessing the relationship between HIV infection and cervical cancer in Côte d'Ivoire: a case-control study
    Georgette Adjorlolo-Johnson
    Projet RETRO CI, Centers for Disease Control and Prevention, Global HIV AIDS Program, Abidjan, Cote d Ivoire
    BMC Infect Dis 10:242. 2010
    ..We conducted a case-control study in a West African population to assess the relationship between HIV infection and invasive cervical cancer, taking into account HPV infection and other potential risk factors for cervical cancer...
  11. pmc Identification of ambiguities in the 1994 chronic fatigue syndrome research case definition and recommendations for resolution
    William C Reeves
    Centers for Disease Control and Prevention, Atlanta, Georgia, United States of America
    BMC Health Serv Res 3:25. 2003
    ..Difficulties with accurate case ascertainment contribute to this ignorance...
  12. pmc Implementation of exon arrays: alternative splicing during T-cell proliferation as determined by whole genome analysis
    Toni Whistler
    Chronic Viral Diseases Branch, National Center for Emerging and Zoonotic Infectious Diseases proposed, Centers for Disease Control and Prevention, Atlanta GA 30333, USA
    BMC Genomics 11:496. 2010
    ..We use this system to examine whole genome transcription and alternate exon usage events that are regulated during lymphocyte proliferation in an attempt to evaluate the exon arrays...
  13. pmc Sleep assessment in a population-based study of chronic fatigue syndrome
    Elizabeth R Unger
    Division of Viral and Rickettsial Diseases, National Center for Infectious Diseases, Centers for Disease Control and Prevention, Atlanta, Georgia, USA
    BMC Neurol 4:6. 2004
    ..Conversely, many sleep disorders present similarly to CFS. Few studies characterizing sleep in unselected CFS subjects have been published and none have been performed in cases identified from population-based studies...
  14. doi request reprint Optimization of SELDI-TOF protein profiling for analysis of cervical mucous
    Gitika Panicker
    Centers for Disease Control and Prevention, Coordinating Center for Infectious Diseases, Atlanta, Georgia 30333, USA
    J Proteomics 71:637-46. 2009
    ..Current data showed that optimizing pre-analytical parameters can help in standardization and reproducibility of protein profiles produced by cervical mucous, and thus can be used for protein biomarker discovery with the SELDI platform...
  15. ncbi request reprint In situ diagnosis of human papillomaviruses
    E R Unger
    Human Papillomavirus Section, Exanthems and Herpesvirus Branch, National Center for Infectious Diseases, Centers for Disease Control and Prevention, Atlanta, Georgia, USA
    Clin Lab Med 20:289-301, vi. 2000
    ..The major limitations of the method are the potential for error in HPV typing because of probe cross-hybridization and relatively low sensitivity if the method is not fully optimized...
  16. ncbi request reprint Detection of human papillomavirus in archival tissues. Comparison of in situ hybridization and polymerase chain reaction
    E R Unger
    Department of Pathology and Laboratory Medicine, Emory University School of Medicine, Atlanta, Georgia, USA
    J Histochem Cytochem 46:535-40. 1998
    ..This degree of concordance required individual optimization of assay conditions for each block. ISH and PCR assays for HPV yield complementary results, and both can be successfully applied to archival tissues...
  17. pmc Human papillomavirus (HPV) DNA copy number is dependent on grade of cervical disease and HPV type
    D C Swan
    National Center for Infectious Diseases, Centers for Disease Control and Prevention, Public Health Service, U S Department of Health and Human Services, Atlanta, Georgia 30333, USA
    J Clin Microbiol 37:1030-4. 1999
    ..This study suggests that the clinical usefulness of HPV quantitation requires reassessment and is assay dependent...
  18. pmc Comparison of human papillomavirus detection and typing by cycle sequencing, line blotting, and hybrid capture
    S D Vernon
    Centers for Disease Control and Prevention, Atlanta, Georgia 30333, USA
    J Clin Microbiol 38:651-5. 2000
    ....
  19. ncbi request reprint Real-time PCR-based fluorescent assay for quantitation of human papillomavirus types 6, 11, 16, and 18
    R A Tucker
    Human Papillomavirus Section, National Center for Infectious Diseases, Centers for Disease Control and Prevention, Public Health Service, US Department of Health and Human Services, Atlanta, GA 30333, USA
    Mol Diagn 6:39-47. 2001
    ..Quantitation of human papillomavirus (HPV) DNA in clinical samples may yield important clinical information...
  20. pmc Validation of array-based gene expression profiles by real-time (kinetic) RT-PCR
    M S Rajeevan
    Division of Viral and Rickettsial Diseases, National Center for Infectious Diseases, Centers for Disease Control and Prevention, U S Department of Health and Human Services, Atlanta, GA 30333, USA
    J Mol Diagn 3:26-31. 2001
    ..Real-time RT-PCR based on LightCycler technology is well-suited to validate DNA array results because it is quantitative, rapid, and requires 1000-fold less RNA than conventional assays...
  21. ncbi request reprint Latent Epstein-Barr virus infection is an unlikely event in the pathogenesis of immunoproliferative small intestinal disease
    F K Baddoura
    Department of Pathology and Laboratory Medicine, Emory University School of Medicine, Atlanta, Georgia
    Cancer 74:1699-705. 1994
    ..One such environmental factor, the Epstein-Barr virus (EBV), has been associated with other B-cell lymphoproliferative disorders...
  22. doi request reprint Factors associated with prevalent abnormal anal cytology in a large cohort of HIV-infected adults in the United States
    L Conley
    National Center for HIV AIDS, Viral Hepatitis, STD, and TB Prevention, Centers for Disease Control and Prevention, Atlanta, Georgia 30333, USA
    J Infect Dis 202:1567-76. 2010
    ..The prevalence of and risk factors for abnormal anal cytology among men and women with human immunodeficiency virus (HIV) infection have not been extensively investigated...
  23. ncbi request reprint Use of real-time quantitative PCR to validate the results of cDNA array and differential display PCR technologies
    M S Rajeevan
    Division of Viral and Rickettsial Diseases, National Center for Infectious Diseases, Ceners for Disease Control and Prevention, US Department of Health and Public Services, Atlanta, Georgia 30333, USA
    Methods 25:443-51. 2001
    ....
  24. ncbi request reprint Human papillomaviruses: into the new millennium
    E R Unger
    Division of Viral and Rickettsial Diseases, National Center for Infectious Diseases, Centers for Disease Control and Prevention, Atlanta, Georgia 30333, USA
    Obstet Gynecol Clin North Am 28:653-66, vii-viii. 2001
    ..Current knowledge about HPV virology, epidemiology, testing, and the prospects for vaccination and other prevention measures is summarized...
  25. doi request reprint Monitoring HPV type-specific prevalence over time through clinic-based surveillance: a perspective on vaccine effectiveness
    N H Gaffga
    Centers for Disease Control and Prevention, National Center for HIV, Viral Hepatitis, STD, and TB Prevention, Division of STD Prevention, Epidemiology and Surveillance Branch, Atlanta, GA 30333, United States
    Vaccine 30:1959-64. 2012
    ..With sufficient sample size and stable population characteristics, clinic-based surveillance systems can contribute to monitoring HPV vaccine impact in the cervical screening population...
  26. ncbi request reprint Glucocorticoid receptor polymorphisms and haplotypes associated with chronic fatigue syndrome
    M S Rajeevan
    Division of Viral and Rickettsial Diseases, National Center for Infectious Diseases, Centers for Disease Control and Prevention, Atlanta, GA 30333, USA
    Genes Brain Behav 6:167-76. 2007
    ....
  27. ncbi request reprint Improved detection of viral RNA isolated from liquid-based cytology samples
    T A Tarkowski
    Viral Exanthems and Herpesvirus Branch, Division of Viral and Rickettsial Diseases, Centers for Disease Control and Prevention, 1600 Clifton Road, Atlanta, GA 30333, USA
    Mol Diagn 6:125-30. 2001
    ..With chemiluminscent Southern blot detection, samples with one HPV-positive cell in 30,000 were consistently detected. CONCLUSION: PreservCyt-fixed cells can yield RNA suitable for molecular assays even after one year of storage...
  28. pmc Clinical determinants of survival from stage Ib cervical cancer in an inner-city hospital
    W W Thoms
    Department of Radiation Oncology, Emory University School of Medicine, Marietta, GA 30060, USA
    J Natl Med Assoc 90:303-8. 1998
    ..Age, race, histology, and cervical lesion size were not significantly associated with survival...
  29. ncbi request reprint Exploration of statistical dependence between illness parameters using the entropy correlation coefficient
    R Cameron Craddock
    Centers for Disease Control and Prevention, Viral Exanthems and Herpesvirus Branch, Atlanta, GA 30333, USA
    Pharmacogenomics 7:421-8. 2006
    ..Highly related variables are candidates for data reduction, and novel relationships could lead to hypotheses regarding the pathogenesis of CFS...
  30. ncbi request reprint Longitudinal measures of human papillomavirus 6 and 11 viral loads and antibody response in children with recurrent respiratory papillomatosis
    Elizabeth M Maloney
    Division of Viral and Rickettsial Diseases, Centers for Disease Control and Prevention, Atlanta, GA 30333, USA
    Arch Otolaryngol Head Neck Surg 132:711-5. 2006
    ....
  31. ncbi request reprint Gene expression correlates of unexplained fatigue
    Toni Whistler
    Centers for Disease Control and Prevention, Viral Exanthems and Herpesvirus Branch, Atlanta, GA 30333, USA
    Pharmacogenomics 7:395-405. 2006
    ..Gene expression correlates of other phenotypic measures in the CFS Computational Challenge (C3) data set could be useful. Future studies of CFS should include as many precise measures of disease phenotype as is practical...
  32. ncbi request reprint Identifying illness parameters in fatiguing syndromes using classical projection methods
    Gordon Broderick
    University of Alberta, Institute for Biomolecular Design, Edmonton, Alberta, T6G 2H7, Canada
    Pharmacogenomics 7:407-19. 2006
    ....
  33. ncbi request reprint Human papillomavirus type 16 variant assignment by pyrosequencing
    David C Swan
    Division of Viral and Rickettsial Diseases, National Center for Infectious Diseases, Centers for Disease Control and Prevention, Public Health Service, U S Department of Health and Human Services, Atlanta, GA 30333, USA
    J Virol Methods 136:166-70. 2006
    ..Pyrosequencing of 97 HPV16-positive exfoliated cervical samples confirmed the Sanger sequencing results; however pyrosequencing identified additional variants in several samples containing mixed variants...
  34. pmc Simultaneous amplification and identification of 25 human papillomavirus types with Templex technology
    Jian Han
    Genaco Biomedical Products, Inc, Huntsville, Alabama 35805, USA
    J Clin Microbiol 44:4157-62. 2006
    ..The entire Templex procedure, including DNA extraction, can be completed within 5 hours, providing a rapid and reliable diagnostic tool for HPV detection and typing that is amenable to automation...
  35. ncbi request reprint Coping styles in people with chronic fatigue syndrome identified from the general population of Wichita, KS
    Urs M Nater
    Viral Exanthems and Herpesvirus Branch, Division of Viral and Rickettsial Diseases, National Center for Infectious Diseases, Centers for Disease Control and Prevention, Atlanta, GA, USA
    J Psychosom Res 60:567-73. 2006
    ..We assessed coping styles in persons with unexplained fatigue and nonfatigued controls in a population-based study...
  36. ncbi request reprint Effect of specimen order on Chlamydia trachomatis and Neisseria gonorrhoeae test performance and adequacy of Papanicolaou smear
    Khalil G Ghanem
    Johns Hopkins University School of Medicine, Bayview Medical Center, 4940 Eastern Avenue B3 North, Baltimore, MD 21224, USA
    J Pediatr Adolesc Gynecol 19:23-30. 2006
    ..To evaluate the effect of specimen collection order on the performance of diagnostic tests for Chlamydia trachomatis (CT) and Neisseria gonorrhoeae (GC), and the specimen adequacy of ThinPrep Papanicolaou (Pap) smears...
  37. ncbi request reprint Quantitation of site-specific HPV 16 DNA methylation by pyrosequencing
    Mangalathu S Rajeevan
    Division of Viral and Rickettsial Diseases, National Center for Infectious Diseases, Centers for Disease Control and Prevention, 1600 Clifton Road, MSG41, Atlanta, GA 30333, USA
    J Virol Methods 138:170-6. 2006
    ..Pyrosequencing provides a quantitative site-specific assessment of methylation at multiple CpG sites without cloning, and is thus suited to large-scale molecular epidemiologic studies...
  38. ncbi request reprint Human papillomavirus infection and cervical cytology in women screened for cervical cancer in the United States, 2003-2005
    S Deblina Datta
    Centers for Disease Control and Prevention, Atlanta, Georgia 30333, USA
    Ann Intern Med 148:493-500. 2008
    ..Millions of women in the United States receive cervical screening in sexually transmitted disease (STD), family planning, and primary care clinical settings...
  39. ncbi request reprint Early adverse experience and risk for chronic fatigue syndrome: results from a population-based study
    Christine Heim
    Viral Exanthems and Herpesvirus Branch, Division of Viral and Rickettsial Diseases, National Center for Infectious Diseases, Centers for Disease Control and Prevention, Atlanta, GA 30322, USA
    Arch Gen Psychiatry 63:1258-66. 2006
    ..Identification of developmental risk factors for CFS is critical to inform pathophysiological research and devise targets for primary prevention...
  40. ncbi request reprint Seroepidemiology of human papillomavirus type 11 in the United States: results from the third National Health And Nutrition Examination Survey, 1991--1994
    Susan Hariri
    National Center for HIV AIDS, Viral Hepatitis, STD, and TB Prevention, Centers for Disease Control and Prevention, Atlanta, Georgia 30333, USA
    Sex Transm Dis 35:298-303. 2008
    ..The objectives of this study were to estimate the national seroprevalence and evaluate predictors of HPV-11 seropositivity...
  41. pmc Effect of storage temperatures on the stability of cytokines in cervical mucous
    Gitika Panicker
    Centers for Disease Control and Prevention, Division of Viral and Rickettsial Diseases, Viral Exanthems and Herpesvirus Branch, Atlanta, GA 30333, USA
    Cytokine 37:176-9. 2007
    ..The results suggest that refrigeration of mucous samples immediately after collection would allow for better conservation of the cytokines in cervical mucous...
  42. ncbi request reprint Quadrivalent Human Papillomavirus Vaccine: Recommendations of the Advisory Committee on Immunization Practices (ACIP)
    Lauri E Markowitz
    Division of STD Prevention, National Center for HIV AIDS, Viral Hepatitis, STD and TB Prevention Proposed, Atlanta, GA 30333, USA
    MMWR Recomm Rep 56:1-24. 2007
    ..Vaccination is not a substitute for routine cervical cancer screening, and vaccinated females should have cervical cancer screening as recommended...
  43. ncbi request reprint Prevalence of HPV infection among females in the United States
    Eileen F Dunne
    Centers for Disease Control and Prevention, Atlanta, GA 30333, USA
    JAMA 297:813-9. 2007
    ..Baseline population prevalence data for HPV infection in the United States before widespread availability of a prophylactic HPV vaccine would be useful...
  44. ncbi request reprint Evaluation of RNA markers for early detection of cervical neoplasia in exfoliated cervical cells
    Martin Steinau
    Division of Viral and Rickettsial Disease, Viral Exanthems and Herpesvirus Branch, Centers for Disease Control and Prevention, 1600 Clifton Road, MS G 41, Atlanta, GA 30333, USA
    Cancer Epidemiol Biomarkers Prev 16:295-301. 2007
    ....
  45. ncbi request reprint Cervical cancer incidence in a prevaccine era in the United States, 1998-2002
    Mona Saraiya
    Division of Cancer Prevention and Control, Centers for Disease Control and Prevention, 4770 Buford Highway, Atlanta, GA 30341, USA
    Obstet Gynecol 109:360-70. 2007
    ..To report the incidence of cervical cancer by geography, race or ethnicity, and histology...
  46. doi request reprint Type-specific reproducibility of the Roche linear array HPV genotyping test
    Martin Steinau
    Division of Viral and Rickettsial Diseases, National Center for Zoonotic, Vector Borne and Enteric Diseases, Coordinating Center for Infectious Diseases, Centers for Disease Control and Prevention, Atlanta, GA 30333, USA
    J Clin Virol 42:412-4. 2008
    ..Inter-assay comparability studies have been performed, but the robustness of type-specific results has neither been emphasized nor has the degree of intra-assay reproducibility been addressed...
  47. ncbi request reprint Molecular characterization of human papillomaviruses by PCR and in situ hybridization
    Suzanne D Vernon
    Centers of Disease Control and Prevention, Atlanta, GA, USA
    Methods Mol Med 97:159-80. 2004
  48. ncbi request reprint Seroprevalence of human papillomavirus type 16 infection in the United States
    Katherine M Stone
    Division of STD Prevention, National Center for HIV, STD and TB Prevention, Centers for Disease Control and Prevention, Atlanta, Georgia 30333, USA
    J Infect Dis 186:1396-402. 2002
    ..Information on HPV-16 seroepidemiology will be important for designing prevention efforts including vaccine programs...
  49. ncbi request reprint Utility of the blood for gene expression profiling and biomarker discovery in chronic fatigue syndrome
    Suzanne D Vernon
    Division of Viral and Rickettsial Diseases, National Center for Infectious Diseases, Centers for Disease Control and Prevention, 1600 Clifton Road, Atlanta, GA 30333, USA
    Dis Markers 18:193-9. 2002
    ..These results successfully demonstrate the utility of the blood for gene expression profiling to distinguish subjects with CFS from healthy controls and for identifying genes that could serve as CFS biomarkers...
  50. ncbi request reprint Factor analysis of symptoms among subjects with unexplained chronic fatigue: what can we learn about chronic fatigue syndrome?
    Rosane Nisenbaum
    Viral Exhanthems and Herpesvirus Branch, Division of Viral and Rickettsial Diseases, National Center for Infectious Diseases CDC, 1600 Clifton Road, Mail Stop A 15, Building 6, Room 116, Atlanta, GA 30333, USA
    J Psychosom Res 56:171-8. 2004
    ..Our objective was to compare the 1994 CFS case-defining symptoms with those identified by factor analysis...
  51. ncbi request reprint Molecular quality of exfoliated cervical cells: implications for molecular epidemiology and biomarker discovery
    Angelique H Habis
    Centers for Disease Control and Prevention, U S Public Health Service, U S Department of Health and Human Services, Atlanta, GA, USA
    Cancer Epidemiol Biomarkers Prev 13:492-6. 2004
    ..However, with a sensitive gold particle-based detection method, reproducible microarray results were obtained using this RNA...
  52. ncbi request reprint Epidemiology of human papillomavirus infection and abnormal cytologic test results in an urban adolescent population
    Trudee A Tarkowski
    National Center for Infectious Diseases, Centers for Disease Control and Prevention, Public Health Service, US Department of Health and Human Services, Atlanta, Georgia, USA
    J Infect Dis 189:46-50. 2004
    ..0% had high- or low-grade squamous intraepithelial lesions) and were significantly associated with detection of HPV (P=.0001); however, most (51.6%) subjects with HPV had normal cytologic test results...
  53. ncbi request reprint Predictors of remission in juvenile-onset recurrent respiratory papillomatosis
    Snehal Ruparelia
    Centers for Disease Control and Prevention, 1600 Clifton Road, Atlanta, GA 30333, USA
    Arch Otolaryngol Head Neck Surg 129:1275-8. 2003
    ..To determine factors associated with remission of juvenile-onset recurrent respiratory papillomatosis (JORRP)...
  54. ncbi request reprint Impact of RNA extraction from limited samples on microarray results
    Hanna Ojaniemi
    Karolinska Institutet at Huddinge University Hospital, Royal Institute of Technology, Stockholm, Sweden
    Biotechniques 35:968-73. 2003
    ..These experiments illustrate that microarray technology holds great promise for the use of limited clinical samples in the diagnostic setting...
  55. ncbi request reprint Global amplification of sense RNA: a novel method to replicate and archive mRNA for gene expression analysis
    Mangalathu S Rajeevan
    Viral Exanthems and Herpesvirus Branch, Division of Viral and Rickettsial Diseases, National Center for Infectious Diseases, Centers for Disease Control and Prevention, US Department of Health and Human Services, Atlanta, GA 30333, USA
    Genomics 82:491-7. 2003
    ..00001-0.1%). This reflects the high fidelity of sRNA synthesis for mRNA as low as 0.3 copies/cell. sRNA is amplified synthetic mRNA in the 5'-->3' direction; the appropriate template for any gene expression analysis...
  56. ncbi request reprint National registry for juvenile-onset recurrent respiratory papillomatosis
    William C Reeves
    Viral Exanthems and Herpesvirus Branch, Division of Viral and Rickettsial Diseases, National Center for Infectious Diseases, Centers for Disease Control and Prevention, Atlanta, GA 30333, USA
    Arch Otolaryngol Head Neck Surg 129:976-82. 2003
    ..Juvenile-onset recurrent respiratory papillomatosis (JORRP) is an infrequent but debilitating disease. Because JORRP is uncommon, it has proven difficult for studies at single institutions to accurately evaluate its natural history...
  57. ncbi request reprint Prevalence and incidence of chronic fatigue syndrome in Wichita, Kansas
    Michele Reyes
    Division of Viral and Rickettsial Diseases, National Center for Infectious Diseases, Centers for Disease Control and Prevention, Public Health Service, US Department of Health and Human Services, Atlanta, GA 30333, USA
    Arch Intern Med 163:1530-6. 2003
    ....
  58. ncbi request reprint Molecular markers for early detection of cervical neoplasia
    Elizabeth R Unger
    Division of Viral and Rickettsial Diseases, National Center for Infectious Diseases, Centers for Disease Control and Prevention, Public Health Service, US Department of Health and Human Services, Atlanta, GA 30333, USA
    Dis Markers 20:103-16. 2004
  59. ncbi request reprint Modifying differential display polymerase chain reaction to detect relative changes in gene expression profiles
    Daya G Ranamukhaarachchi
    Viral Exanthems and Herpesvirus Branch, Division of Viral and Rickettsial Diseases, National Center for Infectious Diseases, Centers for Disease Control and Prevention, U S Department of Health and Human Services, Atlanta, GA 30333, USA
    Anal Biochem 306:343-6. 2002
  60. ncbi request reprint Differential-display PCR of peripheral blood for biomarker discovery in chronic fatigue syndrome
    Martin Steinau
    Division of Viral and Rickettsial Diseases, National Center for Infectious Diseases, Centers for Disease Control and Prevention, 1600 Clifton Rd, MSG 41, Atlanta, GA 30333, USA
    J Mol Med (Berl) 82:750-5. 2004
    ..The real-time reverse-transcription PCR assays that we developed for assay of these biomarkers will facilitate high-throughput testing of these additional samples...
  61. ncbi request reprint Correlates of cervical mucosal antibodies to human papillomavirus 16: results from a case control study
    Cynthia Bierl
    Viral Exanthems and Herpesvirus Branch, Division of Viral and Rickettsial Diseases, Centers for Disease Control and Prevention, Atlanta, GA 30333, USA
    Gynecol Oncol 99:S262-8. 2005
    ..We performed this analysis to determine correlates of HPV-16-specific mucosal antibody response in women at high risk for infection with HPV...
  62. ncbi request reprint Association of Chlamydia trachomatis with persistence of high-risk types of human papillomavirus in a cohort of female adolescents
    Erika Samoff
    Division of Sexually Transmitted Disease Prevention, National Center for HIV, STD, and TB Prevention, Centers for Disease Control and Prevention, Atlanta, GA 30333, USA
    Am J Epidemiol 162:668-75. 2005
    ..8, 95% confidence interval: 1.6, 4.9). The association between chlamydia infection and cervical cancer may be due to an effect of chlamydia infection on persistence of high-risk HPV...
  63. pmc Human papillomavirus and cervical cancer
    Elizabeth R Unger
    Centers for Disease Control and Prevention, Atlanta, Georgia 30333, USA
    Emerg Infect Dis 10:2031-2. 2004
  64. ncbi request reprint The effect of correct and consistent condom use on chlamydial and gonococcal infection among urban adolescents
    Gabriela Paz-Bailey
    National Center for HIV, STD, and TB Prevention, Centers for Disease Control and Prevention, Atlanta, GA, USA
    Arch Pediatr Adolesc Med 159:536-42. 2005
    ..To evaluate the relationship between self-reported correct and consistent condom use and chlamydial and gonococcal infection...
  65. ncbi request reprint Gene expression profiling of dysplastic differentiation in cervical epithelial cells harboring human papillomavirus 16
    Daya G Ranamukhaarachchi
    Division of Viral and Rickettsial Diseases, National Center for Infectious Diseases, Centers for Disease Control and Prevention, Public Health Service US DHHS, Atlanta, GA 30333, USA
    Genomics 85:727-38. 2005
    ..Some of the genes with altered expression identified in this model of dysplastic differentiation may be useful biomarkers for early detection of cervical neoplasia and other HPV-associated oropharyngeal and anogenital cancers...
  66. pmc Gene expression profile of cervical tissue compared to exfoliated cells: impact on biomarker discovery
    Martin Steinau
    Centers for Disease Control and Prevention, Atlanta, GA, USA
    BMC Genomics 6:64. 2005
    ..However, because of keratinization and terminal differentiation it is not clear that these cells have an mRNA profile representative of cervical tissue, and that the profile can distinguish the lesions targeted for early detection...
  67. ncbi request reprint Seroprevalence of human papillomavirus type 16 in children
    Eileen F Dunne
    Division of STD Prevention, National Center for HIV, STD, and TB Prevention, National Center for Infectious Diseases, Centers for Disease Control and Prevention, Atlanta, Georgia 30333, USA
    J Infect Dis 191:1817-9. 2005
    ..To explain HPV-16 seropositivity in this population, further study is required...
  68. ncbi request reprint Human papillomavirus type 16 E2 and E6/E7 variants
    David C Swan
    U S Department of Health and Human Services, National Center for Infectious Diseases, Centers for Disease Control and Prevention, Public Health Service, Atlanta, GA 30333, USA
    Gynecol Oncol 96:695-700. 2005
    ....
  69. ncbi request reprint Epidemiologic and viral factors associated with cervical neoplasia in HPV-16-positive women
    Mangalathu S Rajeevan
    Centers for Disease Control and Prevention, Atlanta, GA 30333, USA
    Int J Cancer 115:114-20. 2005
    ..Cellular proliferation and differentiation pathways affected by HPV should be investigated as biomarkers for cervical cancer screening...
  70. ncbi request reprint Low-dose topical delivery of all-trans retinoic acid for cervical intraepithelial neoplasia II and III
    Mack T Ruffin
    Department of Family Medicine, University of Michigan, 1018 Fuller Street, Ann Arbor, MI 48109 0708, USA
    Cancer Epidemiol Biomarkers Prev 13:2148-52. 2004
    ..The objective of this study was to determine an effective dose for all-trans retinoic acid (atRA) delivered with a cervical cap and sponge for 4 days to women with cervical intraepithelial neoplasia (CIN) II/III...
  71. ncbi request reprint The effect of time interval between referral and colposcopy on detection of human papillomavirus DNA and on outcome of biopsy
    Zuzana Berkova
    Department of Molecular Virology and Microbiology, Baylor College of Medicine, Houston, TX 77030, USA
    Am J Obstet Gynecol 188:932-7. 2003
    ....
  72. ncbi request reprint Assessment of normal variability in peripheral blood gene expression
    Catherine Campbell
    Division of Viral and Rickettsial Diseases, National Center for Infectious Diseases, Centers for Disease Control and Prevention, 1600 Clifton Road, Atlanta, GA 30333, USA
    Dis Markers 18:201-6. 2002
    ..These results suggest that observed variation was due to experimental variability...
  73. pmc DNA and RNA references for qRT-PCR assays in exfoliated cervical cells
    Martin Steinau
    Human Papillomavirus Program, Centers for Disease Control and Prevention, 1600 Clifton Rd, MS G41, Atlanta, GA 30333, USA
    J Mol Diagn 8:113-8. 2006
    ..These genes also showed the highest correlation with DNA contents in the same samples. If special attention to intraepithelial lesions is appropriate, RPL4 and PGK1 are recommended as the best combination of two genes...
  74. pmc Short duration of elevated vIRF-1 expression during lytic replication of human herpesvirus 8 limits its ability to block antiviral responses induced by alpha interferon in BCBL-1 cells
    Veronika P Pozharskaya
    Winship Cancer Institute, Emory University, 1365 B Clifton Road N E, Atlanta, GA 30322, USA
    J Virol 78:6621-35. 2004
    ....
  75. ncbi request reprint Exploration of neuroendocrine and immune gene expression in peripheral blood mononuclear cells
    Ainsley C Nicholson
    Division of Viral and Rickettsial Diseases, National Center for Infectious Diseases, Centers for Disease Control and Prevention, 1600 Clifton Road, Atlanta, GA 30333, USA
    Brain Res Mol Brain Res 129:193-7. 2004
    ....
  76. doi request reprint Alterations in diurnal salivary cortisol rhythm in a population-based sample of cases with chronic fatigue syndrome
    Urs M Nater
    Chronic Viral Diseases Branch, Centers for Disease Control and Prevention, Mail Stop A 15, Atlanta, GA 30333, USA
    Psychosom Med 70:298-305. 2008
    ..Previous studies of CFS patients have implicated the hypothalamic-pituitary-adrenal axis and the immune system in the pathophysiology of CFS, although results have been equivocal...