Michael C Thigpen
Affiliation: Centers for Disease Control and Prevention
- Antiretroviral preexposure prophylaxis for heterosexual HIV transmission in BotswanaMichael C Thigpen
Division of HIV AIDS Prevention, Centers for Disease Control and Prevention, Atlanta, USA
N Engl J Med 367:423-34. 2012..Preexposure prophylaxis with antiretroviral agents has been shown to reduce the transmission of human immunodeficiency virus (HIV) among men who have sex with men; however, the efficacy among heterosexuals is uncertain...
- Nursing home outbreak of invasive group a streptococcal infections caused by 2 distinct strainsMichael C Thigpen
Respiratory Diseases Branch, Division of Bacterial and Mycotic Diseases, National Center for Infectious Diseases, Atlanta, GA 30333, USA
Infect Control Hosp Epidemiol 28:68-74. 2007..To identify factors contributing to a cluster of deaths from invasive group A streptococcus (GAS) infection in a nursing home facility and to prevent additional cases...
- Bacterial meningitis in the United States, 1998-2007Michael C Thigpen
Centers for Disease Control and Prevention, Atlanta, USA
N Engl J Med 364:2016-25. 2011..More recent prevention measures such as the pneumococcal conjugate vaccine and universal screening of pregnant women for group B streptococcus (GBS) have further changed the epidemiology of bacterial meningitis...
- Invasive group A streptococcal infection in older adults in long-term care facilities and the community, United States, 1998-2003Michael C Thigpen
Centers for Disease Control and Prevention, Atlanta, Georgia, USA
Emerg Infect Dis 13:1852-9. 2007..95%, p<0.01). In multivariate logistic regression modeling, LTCF residence remained an independent predictor of death. Additional prevention strategies against GAS infection in this high-risk population are urgently needed...
- Associations between peripheral Plasmodium falciparum malaria parasitemia, human immunodeficiency virus, and concurrent helminthic infection among pregnant women in MalawiMichael C Thigpen
Malaria Branch, Division of Parasitic Diseases, Centers for Disease Control and Prevention, Atlanta, GA, USA
Am J Trop Med Hyg 84:379-85. 2011..2-3.0 for HIV; adjusted odds ratio = 1.9 and 95% confidence interval = 1.03-3.5 for hookworm). Concurrent helminthic infection had both positive and negative effects on malaria parasitemia among pregnant women in Malawi...
- Legionnaires' disease among residents of a long-term care facility: the sentinel event in a community outbreakChristina R Phares
Epidemic Intelligence Service Program, National Center for Infectious Diseases, Centers for Disease Control and Prevention, Atlanta, GA 30333, USA
Am J Infect Control 35:319-23. 2007..A long-term care facility (LTCF) reported an outbreak of Legionnaires' disease (LD) in September 2004...
- Group a streptococcal disease in long-term care facilities: descriptive epidemiology and potential control measuresHannah T Jordan
Respiratory Diseases Branch, National Center for Immunization and Respiratory Diseases, Centers for Disease Control and Prevention, Atlanta, GA, USA
Clin Infect Dis 45:742-52. 2007..We highlight well-accepted prevention and control strategies that can be employed during investigation and control of GAS infection outbreaks in LTCFs...
- Triple-antiretroviral prophylaxis to prevent mother-to-child HIV transmission through breastfeeding--the Kisumu Breastfeeding Study, Kenya: a clinical trialTimothy K Thomas
Division of HIV AIDS Prevention, Us centers for Disease Control and Prevention CDC, Atlanta, Georgia, USA
PLoS Med 8:e1001015. 2011....
- Effect of a point-of-use water treatment and safe water storage intervention on diarrhea in infants of HIV-infected mothersJulie R Harris
Epidemic Intelligence Service, Office of Workforce and Career Development, Centers for Disease Control and Prevention, Atlanta, Georgia, USA
J Infect Dis 200:1186-93. 2009..Among infants who were weaned early, provision of safe water may be insufficient to prevent weaning-associated diarrhea...
- CD4(+) cell count, viral load, and drug resistance patterns among heterosexual breakthrough HIV infections in a study of oral preexposure prophylaxisLovemore I Chirwa
aCDC BOTUSA, Gaborone, Botswana bDivision of HIV AIDS Prevention, Centers for Disease Control and Prevention, Atlanta, Georgia, USA
AIDS 28:223-6. 2014..Of the four participants who seroconverted on-study while receiving tenofovir/emtricitabine, none became infected as a result of drug-resistant HIV; moreover, no resistance mutations emerged following seroconversion. ..
- Effectiveness of repeat single-dose nevirapine for prevention of mother-to-child transmission of HIV-1 in repeat pregnancies in UgandaMichelle McConnell
Global AIDS Program, Centers for Disease Control and Prevention, Atlanta, GA, USA
J Acquir Immune Defic Syndr 46:291-6. 2007..Given detection of resistant mutants among women who receive SDNVP, concerns have arisen over the efficacy of SDNVP in repeat pregnancies...
- HIV-1 drug resistance emergence among breastfeeding infants born to HIV-infected mothers during a single-arm trial of triple-antiretroviral prophylaxis for prevention of mother-to-child transmission: a secondary analysisClement Zeh
Division of HIV AIDS Prevention, US Centers for Disease Control and Prevention, Kisumu, Kenya
PLoS Med 8:e1000430. 2011..Here, we present findings from a KiBS trial secondary analysis that evaluated the emergence of maternal ARV-associated resistance among 32 HIV-infected breastfed infants...
- Safety and toxicity of sulfadoxine/pyrimethamine: implications for malaria prevention in pregnancy using intermittent preventive treatmentPhilip J Peters
Division of Infectious Diseases, Emory University School of Medicine, Atlanta, Georgia 30303, USA
Drug Saf 30:481-501. 2007..Given the documented benefits of IPTp-SP in malaria endemic areas of Africa, access to this treatment for pregnant women should continue to expand...
- Prevention of human immunodeficiency virus-1 transmission to the infant through breastfeeding: new developmentsAthena P Kourtis
Division of Reproductive Health, National Center for Chronic Disease Prevention and Health Promotion, Centers for Disease Control and Prevention, Atlanta, GA, USA
Am J Obstet Gynecol 197:S113-22. 2007..Passive (antibodies) and active (vaccine) immunoprophylaxis will also soon begin to be tested. This paper focuses on current and planned research on strategies to prevent breastfeeding transmission of HIV...
- Extended antiretroviral prophylaxis to reduce breast-milk HIV-1 transmissionNewton I Kumwenda
Bloomberg School of Public Health, Johns Hopkins University, Baltimore, MD 21205, USA
N Engl J Med 359:119-29. 2008..Effective strategies are urgently needed to reduce mother-to-child transmission of human immunodeficiency virus type 1 (HIV-1) through breast-feeding in resource-limited settings...
- Nevirapine resistance in women and infants after first versus repeated use of single-dose nevirapine for prevention of HIV-1 vertical transmissionTamara S Flys
Department of Pathology, Johns Hopkins University School of Medicine, Baltimore, Maryland 21205, USA
J Infect Dis 198:465-9. 2008..NVP resistance was detected in a similar proportion of infants born to SD NVP-naive versus SD NVP-experienced women. Repeated use of SD NVP to prevent HIV transmission does not appear to influence NVP resistance...