William M Switzer

Summary

Affiliation: Centers for Disease Control and Prevention
Country: USA

Publications

  1. doi request reprint Human T cell lymphotropic virus type 1 infection among U.S. thalassemia patients
    William M Switzer
    Laboratory Branch, Division of HIV AIDS Prevention, National Center for HIV, Hepatitis, STD, and TB Prevention, Centers for Disease Control and Prevention, Atlanta, GA 30333, USA
    AIDS Res Hum Retroviruses 29:1006-9. 2013
  2. pmc No association of xenotropic murine leukemia virus-related viruses with prostate cancer
    William M Switzer
    Laboratory Branch, Division of HIV AIDS Prevention, National Center for HIV AIDS, Viral Hepatitis, STD, and TB Prevention, Centers for Disease Control and Prevention, Atlanta, Georgia, United States of America
    PLoS ONE 6:e19065. 2011
  3. ncbi request reprint Polymerase chain reaction assays for the diagnosis of infection with the porcine endogenous retrovirus and the detection of pig cells in human and nonhuman recipients of pig xenografts
    W M Switzer
    Division of AIDS, Sexually Transmitted Diseases, Centers for Disease Control and Prevention, Public Health Service, U S Department of Health and Human Services, Atlanta, Georgia 30333, USA
    Transplantation 68:183-8. 1999
  4. doi request reprint Coinfection with HIV-1 and simian foamy virus in West Central Africans
    William M Switzer
    Division of HIV AIDS Prevention, National Center for HIV AIDS, Viral Hepatitis, Sexually Transmitted Diseases, and Tuberculosis Prevention, Centers for Disease Control and Prevention, Atlanta, Georgia
    J Infect Dis 197:1389-93. 2008
  5. pmc Ancient origin and molecular features of the novel human T-lymphotropic virus type 3 revealed by complete genome analysis
    William M Switzer
    Laboratory Branch, Division of HIV AIDS Prevention, National Center for HIV, STD, and TB Prevention, Centers for Disease Control and Prevention, 1600 Clifton Road, MS G 45, Atlanta, GA 30333, USA
    J Virol 80:7427-38. 2006
  6. ncbi request reprint The epidemiology of simian immunodeficiency virus infection in a large number of wild- and captive-born chimpanzees: evidence for a recent introduction following chimpanzee divergence
    William M Switzer
    HIV and Retrovirology Branch, Division of HIV AIDS Prevention, National Center for HIV, STD, and TB Prevention, Centers for Disease Control and Prevention, Atlanta, Georgia 30333, USA
    AIDS Res Hum Retroviruses 21:335-42. 2005
  7. ncbi request reprint Ancient co-speciation of simian foamy viruses and primates
    William M Switzer
    HIV and Retrovirology Branch, Division of HIV AIDS Prevention, National Center for HIV, STD, and TB Prevention, Centers for Disease Control and Prevention, 1600 Clifton Road, MS G 19, Atlanta, Georgia 30333, USA
    Nature 434:376-80. 2005
  8. pmc Frequent simian foamy virus infection in persons occupationally exposed to nonhuman primates
    William M Switzer
    HIV and Retrovirology Branch, Division of AIDS, STD, and TB Laboratory Research, National Center for HIV, STD, and TB Prevention, Centers for Disease Control and Prevention, Atlanta, Georgia 30333, USA
    J Virol 78:2780-9. 2004
  9. pmc Conference highlights of the 15th International Conference on Human Retrovirology: HTLV and related retroviruses, 4-8 June 2011, Leuven, Gembloux, Belgium
    Fabiola Martin
    Centre for Immunology and Infection, Department of Biology, Hull and York Medical School, University of York, York, UK
    Retrovirology 8:86. 2011
  10. pmc Serologic and PCR testing of persons with chronic fatigue syndrome in the United States shows no association with xenotropic or polytropic murine leukemia virus-related viruses
    Brent C Satterfield
    Cooperative Diagnostics, LLC, Greenwood, SC 29646, USA
    Retrovirology 8:12. 2011

Collaborators

Detail Information

Publications24

  1. doi request reprint Human T cell lymphotropic virus type 1 infection among U.S. thalassemia patients
    William M Switzer
    Laboratory Branch, Division of HIV AIDS Prevention, National Center for HIV, Hepatitis, STD, and TB Prevention, Centers for Disease Control and Prevention, Atlanta, GA 30333, USA
    AIDS Res Hum Retroviruses 29:1006-9. 2013
    ..In addition, appropriate counseling and follow-up of HTLV-infected patients are warranted...
  2. pmc No association of xenotropic murine leukemia virus-related viruses with prostate cancer
    William M Switzer
    Laboratory Branch, Division of HIV AIDS Prevention, National Center for HIV AIDS, Viral Hepatitis, STD, and TB Prevention, Centers for Disease Control and Prevention, Atlanta, Georgia, United States of America
    PLoS ONE 6:e19065. 2011
    ..We used broadly reactive PCR and Western blot (WB) assays to detect infection with XMRV and related murine leukemia viruses (MLV)...
  3. ncbi request reprint Polymerase chain reaction assays for the diagnosis of infection with the porcine endogenous retrovirus and the detection of pig cells in human and nonhuman recipients of pig xenografts
    W M Switzer
    Division of AIDS, Sexually Transmitted Diseases, Centers for Disease Control and Prevention, Public Health Service, U S Department of Health and Human Services, Atlanta, Georgia 30333, USA
    Transplantation 68:183-8. 1999
    ..The ability of PERV to infect human cells in vitro has heightened safety concerns regarding the transmission of PERV to pig xenograft recipients...
  4. doi request reprint Coinfection with HIV-1 and simian foamy virus in West Central Africans
    William M Switzer
    Division of HIV AIDS Prevention, National Center for HIV AIDS, Viral Hepatitis, Sexually Transmitted Diseases, and Tuberculosis Prevention, Centers for Disease Control and Prevention, Atlanta, Georgia
    J Infect Dis 197:1389-93. 2008
    ..The findings of the present study suggest opportunities for bloodborne and sexual transmission of SFV and highlight the importance of defining the clinical consequences of dual infections...
  5. pmc Ancient origin and molecular features of the novel human T-lymphotropic virus type 3 revealed by complete genome analysis
    William M Switzer
    Laboratory Branch, Division of HIV AIDS Prevention, National Center for HIV, STD, and TB Prevention, Centers for Disease Control and Prevention, 1600 Clifton Road, MS G 45, Atlanta, GA 30333, USA
    J Virol 80:7427-38. 2006
    ..The ancient origin of HTLV-3, the broad distribution of STLV-3 in Africa, and the propensity of STLVs to cross species into humans all suggest that HTLV-3 may be prevalent and support the need for expanded surveillance for this virus...
  6. ncbi request reprint The epidemiology of simian immunodeficiency virus infection in a large number of wild- and captive-born chimpanzees: evidence for a recent introduction following chimpanzee divergence
    William M Switzer
    HIV and Retrovirology Branch, Division of HIV AIDS Prevention, National Center for HIV, STD, and TB Prevention, Centers for Disease Control and Prevention, Atlanta, Georgia 30333, USA
    AIDS Res Hum Retroviruses 21:335-42. 2005
    ..The absence of SIVcpz infection in P. t. verus suggests that SIVcpz may not be endemic to this subspecies and implies that SIVcpz may have been introduced more recently into the chimpanzee subspecies following divergence...
  7. ncbi request reprint Ancient co-speciation of simian foamy viruses and primates
    William M Switzer
    HIV and Retrovirology Branch, Division of HIV AIDS Prevention, National Center for HIV, STD, and TB Prevention, Centers for Disease Control and Prevention, 1600 Clifton Road, MS G 19, Atlanta, Georgia 30333, USA
    Nature 434:376-80. 2005
    ..These results indicate that SFVs might have co-speciated with Old World primates for at least 30 million years, making them the oldest known vertebrate RNA viruses...
  8. pmc Frequent simian foamy virus infection in persons occupationally exposed to nonhuman primates
    William M Switzer
    HIV and Retrovirology Branch, Division of AIDS, STD, and TB Laboratory Research, National Center for HIV, STD, and TB Prevention, Centers for Disease Control and Prevention, Atlanta, Georgia 30333, USA
    J Virol 78:2780-9. 2004
    ..Our data highlight the importance of studies to better define the public health implications of zoonotic SFV infections...
  9. pmc Conference highlights of the 15th International Conference on Human Retrovirology: HTLV and related retroviruses, 4-8 June 2011, Leuven, Gembloux, Belgium
    Fabiola Martin
    Centre for Immunology and Infection, Department of Biology, Hull and York Medical School, University of York, York, UK
    Retrovirology 8:86. 2011
    ....
  10. pmc Serologic and PCR testing of persons with chronic fatigue syndrome in the United States shows no association with xenotropic or polytropic murine leukemia virus-related viruses
    Brent C Satterfield
    Cooperative Diagnostics, LLC, Greenwood, SC 29646, USA
    Retrovirology 8:12. 2011
    ..Our findings, together with previous negative reports, do not suggest an association of XMRV or MuLV in the majority of CFS cases...
  11. pmc Ancient, independent evolution and distinct molecular features of the novel human T-lymphotropic virus type 4
    William M Switzer
    Laboratory Branch, Division of HIV AIDS Prevention, National Center for HIV AIDS, Viral Hepatitis, STD, and TB Prevention, Centers for Disease Control and Prevention, Atlanta, GA 30333, USA
    Retrovirology 6:9. 2009
    ..Analysis of full-length genomes can provide basic information on the evolutionary history and replication and pathogenic potential of new viruses...
  12. pmc Genetic characterization of the complete genome of a highly divergent simian T-lymphotropic virus (STLV) type 3 from a wild Cercopithecus mona monkey
    David M Sintasath
    Department of International Health, Johns Hopkins Bloomberg School of Public Health, Baltimore MD 21205, USA
    Retrovirology 6:97. 2009
    ....
  13. doi request reprint Clinical and virological characterization of persistent human infection with simian foamy viruses
    Roumiana S Boneva
    HIV and Retrovirology Branch, Division of AIDS, STD and TB Laboratory Research, National Center for Infectious Diseases, Centers for Disease Control and Prevention, Atlanta, Georgia 30333, USA
    AIDS Res Hum Retroviruses 23:1330-7. 2007
    ..SFV likely transmits to humans through both percutaneous and mucocutaneous exposures to NHP body fluids. Limited follow-up has not identified SFV-associated illness and secondary transmission among humans...
  14. ncbi request reprint Screening for simian foamy virus infection by using a combined antigen Western blot assay: evidence for a wide distribution among Old World primates and identification of four new divergent viruses
    Althaf I Hussain
    HIV and Retrovirology Branch, Division of AIDS, STD, and TB Laboratory Research, Centers for Disease Control and Prevention, Atlanta, GA 30333, USA
    Virology 309:248-57. 2003
    ..These results demonstrate the ability of the CA-WB assay to detect infection in a large number of NHP species, including previously uncharacterized infections with divergent SFVs...
  15. pmc Novel simian foamy virus infections from multiple monkey species in women from the Democratic Republic of Congo
    William M Switzer
    Division of HIV AIDS Prevention, National Center for HIV AIDS, Viral Hepatitis, STD, and TB Prevention, Centers for Disease Control and Prevention, Atlanta, GA 30333, USA
    Retrovirology 9:100. 2012
    ..Phylogenetic analysis was used to define the NHP species origin of SFV. Participants completed questionnaires to capture NHP exposure information...
  16. pmc Absence of evidence of xenotropic murine leukemia virus-related virus infection in persons with chronic fatigue syndrome and healthy controls in the United States
    William M Switzer
    Laboratory Branch, Division of HIV AIDS Prevention, National Center for HIV AIDS, Viral Hepatitis, STD, and TB Prevention, Centers for Disease Control and Prevention, Atlanta, GA 30333, USA
    Retrovirology 7:57. 2010
    ..Blinded PCR and serologic testing were performed at the US Centers for Disease Control and Prevention (CDC) and at two additional laboratories...
  17. pmc Emergence of a novel and highly divergent HTLV-3 in a primate hunter in Cameroon
    Haoqiang Zheng
    Laboratory Branch, Division of HIV AIDS Prevention, National Center for HIV AIDS, Viral Hepatitis, STD, and TB Prevention, Centers for Disease Control and Prevention, Atlanta, GA 30333, USA
    Virology 401:137-45. 2010
    ....
  18. doi request reprint Short communication: Absence of evidence of HTLV-3 and HTLV-4 in patients with large granular lymphocyte (LGL) leukemia
    Yen T Duong
    Laboratory Branch, Division of HIV AIDS Prevention, National Center for HIV, Viral Hepatitis, STD, and TB Prevention, Centers for Disease Control and Prevention, 1600 Clifton Road, Atlanta, GA 30333, USA
    AIDS Res Hum Retroviruses 24:1503-5. 2008
    ..These results suggest that HTLV-3 and HTLV-4 are not the causative agent of LGL leukemia...
  19. pmc Mucosal and systemic antibody responses in humans infected with simian foamy virus
    James E Cummins
    HIV and Retrovirology Branch, Division of AIDS, STD, Centers for Disease Control and Prevention, Atlanta, Georgia 30333, USA
    J Virol 79:13186-9. 2005
    ..These results provide a first comparative evaluation of SFV-specific host mucosal humoral immunity in infected humans and chimpanzees that is characterized by a predominant IgG response and a virtually absent IgA response...
  20. pmc Detection of murine leukemia virus or mouse DNA in commercial RT-PCR reagents and human DNAs
    Haoqiang Zheng
    Laboratory Branch, Division of HIV AIDS Prevention, National Center for HIV AIDS, Viral Hepatitis, STD, and TB Prevention, Centers for Disease Control and Prevention, Atlanta, Georgia, United States of America
    PLoS ONE 6:e29050. 2011
    ..These results identify new sources of MLV contamination and highlight the importance of careful pre-screening of commercial specimens and diagnostic reagents to avoid false-positive MLV PCR results...
  21. pmc No evidence of murine leukemia virus-related viruses in live attenuated human vaccines
    William M Switzer
    Laboratory Branch, Division of HIV AIDS Prevention, National Center for HIV AIDS, Viral Hepatitis, STD, and TB Prevention, Centers for Disease Control and Prevention, Atlanta, Georgia, USA
    PLoS ONE 6:e29223. 2011
    ..To address this possibility, we tested eight live attenuated human vaccines using generic PCR for XMRV and MLV sequences. Viral metagenomics using deep sequencing was also done to identify the possibility of other adventitious agents...
  22. pmc Limited SHIV env diversification in macaques failing oral antiretroviral pre-exposure prophylaxis
    Qi Zheng
    National Center for HIV, Hepatitis, STD, and Prevention, Centers for Disease Control and Prevention, Atlanta, GA, USA
    Retrovirology 9:40. 2012
    ..We investigated viral evolution dynamics in a macaque model of PrEP consisting of repeated rectal exposures to SHIV162P3 in the presence of PrEP...
  23. pmc Development and application of a high-throughput microneutralization assay: lack of xenotropic murine leukemia virus-related virus and/or murine leukemia virus detection in blood donors
    Yanchen Zhou
    Blood Systems Research Institute, Department of Laboratory Medicine, University of California at San Francisco, San Francisco, California 94118, USA
    Transfusion 52:332-42. 2012
    ..Several laboratories have utilized microneutralization assays as a surrogate marker for detection of anti-MLV serologic responses--with up to 25% of prostate cancer patients reported to harbor neutralizing antibody responses...
  24. doi request reprint Demographic but not geographic insularity in HIV transmission among young black MSM
    Alexandra M Oster
    Epidemic Intelligence Service, Scientific Education and Professional Development Program Office, Centers for Disease Control and Prevention, Atlanta, GA, USA
    AIDS 25:2157-65. 2011
    ..To understand patterns of HIV transmission among young black MSM and others in Mississippi...