Brandi N Snyder-Talkington

Summary

Affiliation: Centers for Disease Control and Prevention
Country: USA

Publications

  1. pmc Systematic analysis of multiwalled carbon nanotube-induced cellular signaling and gene expression in human small airway epithelial cells
    Brandi N Snyder-Talkington
    Pathology and Physiology Research Branch, Health Effects Laboratory Division, National Institute for Occupational Safety and Health, Morgantown, West Virginia 26505, USA
    Toxicol Sci 133:79-89. 2013
  2. pmc Multi-walled carbon nanotubes induce human microvascular endothelial cellular effects in an alveolar-capillary co-culture with small airway epithelial cells
    Brandi N Snyder-Talkington
    Pathology and Physiology Research Branch, Health Effects Laboratory Division, National Institute for Occupational Safety and Health, 1095 Willowdale Road, Morgantown, WV 26505 2888, USA
    Part Fibre Toxicol 10:35. 2013
  3. pmc Multi-walled carbon nanotube-induced gene expression in vitro: concordance with in vivo studies
    Brandi N Snyder-Talkington
    Pathology and Physiology Research Branch, Health Effects Laboratory Division, National Institute for Occupational Safety and Health, Morgantown, WV 26505, USA
    Toxicology 328:66-74. 2015
  4. pmc mRNA and miRNA regulatory networks reflective of multi-walled carbon nanotube-induced lung inflammatory and fibrotic pathologies in mice
    Julian Dymacek
    Lane Department of Computer Science and Electrical Engineering, West Virginia University, Morgantown, West Virginia 26506 6070, Pathology and Physiology Research Branch, Health Effects Laboratory Division, National Institute for Occupational Safety and Health, Morgantown, West Virginia 26505, Department of Pharmaceutical Sciences, School of Pharmacy, West Virginia University, Morgantown, West Virginia 26506 and Department of Occupational and Environmental Health Science, School of Public Health, Mary Babb Randolph Cancer Center, West Virginia University, Morgantown, West Virginia 26506 9300
    Toxicol Sci 144:51-64. 2015
  5. pmc System-based identification of toxicity pathways associated with multi-walled carbon nanotube-induced pathological responses
    Brandi N Snyder-Talkington
    Pathology and Physiology Research Branch, Health Effects Laboratory Division, National Institute for Occupational Safety and Health, Morgantown, WV 26505, USA
    Toxicol Appl Pharmacol 272:476-89. 2013
  6. pmc New perspectives for in vitro risk assessment of multiwalled carbon nanotubes: application of coculture and bioinformatics
    Brandi N Snyder-Talkington
    Pathology and Physiology Research Branch, Health Effects Laboratory Division, National Institute for Occupational Safety and Health, Morgantown, WV 26505, USA
    J Toxicol Environ Health B Crit Rev 15:468-92. 2012
  7. doi request reprint Effects of nitrogen-doped multi-walled carbon nanotubes compared to pristine multi-walled carbon nanotubes on human small airway epithelial cells
    Amy L Mihalchik
    Pharmaceutical and Pharmacological Sciences, West Virginia University School of Pharmacy, Morgantown, WV 26505, United States Pathology and Physiology Research Branch, Health Effects Laboratory Division, National Institute for Occupational Safety and Health, Morgantown, WV 26505, United States
    Toxicology 333:25-36. 2015

Collaborators

Detail Information

Publications7

  1. pmc Systematic analysis of multiwalled carbon nanotube-induced cellular signaling and gene expression in human small airway epithelial cells
    Brandi N Snyder-Talkington
    Pathology and Physiology Research Branch, Health Effects Laboratory Division, National Institute for Occupational Safety and Health, Morgantown, West Virginia 26505, USA
    Toxicol Sci 133:79-89. 2013
    ..Gene expression data derived from MWCNT exposure provide information that may be used to elucidate the underlying mode of action of MWCNT in the small airway and suggest potential prognostic gene signatures for risk assessment...
  2. pmc Multi-walled carbon nanotubes induce human microvascular endothelial cellular effects in an alveolar-capillary co-culture with small airway epithelial cells
    Brandi N Snyder-Talkington
    Pathology and Physiology Research Branch, Health Effects Laboratory Division, National Institute for Occupational Safety and Health, 1095 Willowdale Road, Morgantown, WV 26505 2888, USA
    Part Fibre Toxicol 10:35. 2013
    ..This study aimed to determine if an alveolar-capillary co-culture model could determine changes in the vascular endothelium after epithelial exposure to MWCNT...
  3. pmc Multi-walled carbon nanotube-induced gene expression in vitro: concordance with in vivo studies
    Brandi N Snyder-Talkington
    Pathology and Physiology Research Branch, Health Effects Laboratory Division, National Institute for Occupational Safety and Health, Morgantown, WV 26505, USA
    Toxicology 328:66-74. 2015
    ..As coculture gene expression better correlated with in vivo gene expression, we suggest that cellular cocultures may offer enhanced in vitro models for nanoparticle risk assessment and the reduction of in vivo toxicological testing. ..
  4. pmc mRNA and miRNA regulatory networks reflective of multi-walled carbon nanotube-induced lung inflammatory and fibrotic pathologies in mice
    Julian Dymacek
    Lane Department of Computer Science and Electrical Engineering, West Virginia University, Morgantown, West Virginia 26506 6070, Pathology and Physiology Research Branch, Health Effects Laboratory Division, National Institute for Occupational Safety and Health, Morgantown, West Virginia 26505, Department of Pharmaceutical Sciences, School of Pharmacy, West Virginia University, Morgantown, West Virginia 26506 and Department of Occupational and Environmental Health Science, School of Public Health, Mary Babb Randolph Cancer Center, West Virginia University, Morgantown, West Virginia 26506 9300
    Toxicol Sci 144:51-64. 2015
    ....
  5. pmc System-based identification of toxicity pathways associated with multi-walled carbon nanotube-induced pathological responses
    Brandi N Snyder-Talkington
    Pathology and Physiology Research Branch, Health Effects Laboratory Division, National Institute for Occupational Safety and Health, Morgantown, WV 26505, USA
    Toxicol Appl Pharmacol 272:476-89. 2013
    ....
  6. pmc New perspectives for in vitro risk assessment of multiwalled carbon nanotubes: application of coculture and bioinformatics
    Brandi N Snyder-Talkington
    Pathology and Physiology Research Branch, Health Effects Laboratory Division, National Institute for Occupational Safety and Health, Morgantown, WV 26505, USA
    J Toxicol Environ Health B Crit Rev 15:468-92. 2012
    ....
  7. doi request reprint Effects of nitrogen-doped multi-walled carbon nanotubes compared to pristine multi-walled carbon nanotubes on human small airway epithelial cells
    Amy L Mihalchik
    Pharmaceutical and Pharmacological Sciences, West Virginia University School of Pharmacy, Morgantown, WV 26505, United States Pathology and Physiology Research Branch, Health Effects Laboratory Division, National Institute for Occupational Safety and Health, Morgantown, WV 26505, United States
    Toxicology 333:25-36. 2015
    ..Our results indicate that ND-MWCNT induce effects in SAEC over a time and dose-related manner which differ from MWCNT-7. Therefore, the physicochemical characteristics of the materials appear to alter their biological effects. ..