W E Secor

Summary

Affiliation: Centers for Disease Control and Prevention
Country: USA

Publications

  1. ncbi request reprint Mice deficient for 5-lipoxygenase, but not leukocyte-type 12-lipoxygenase, display altered immune responses during infection with Schistosoma mansoni
    W E Secor
    Division of Parasitic Diseases, National Center for Infectious Diseases, Centers for Disease Control and Prevention, Atlanta, Georgia 30341, USA
    Prostaglandins Other Lipid Mediat 56:291-304. 1998
  2. doi request reprint The effects of schistosomiasis on HIV/AIDS infection, progression and transmission
    W Evan Secor
    Division of Parasitic Diseases and Malaria, Center for Global Health, Centers for Disease Control and Prevention, Atlanta, Georgia, USA
    Curr Opin HIV AIDS 7:254-9. 2012
  3. pmc High prevalence of schistosomiasis in Mbita and its adjacent islands of Lake Victoria, western Kenya
    Maurice R Odiere
    Neglected Tropical Diseases Branch, Centre for Global Health Research, Kenya Medical Research Institute, P, O, Box 1578 40100, Kisumu, Kenya
    Parasit Vectors 5:278. 2012
  4. pmc Integrated community-directed intervention for schistosomiasis and soil transmitted helminths in western Kenya - a pilot study
    Pauline N M Mwinzi
    Center for Global Health Research, Kenya Medical Research Institute, Kisumu, Kenya
    Parasit Vectors 5:182. 2012
  5. ncbi request reprint Below the belt: new insights into potential complications of HIV-1/schistosome coinfections
    W Evan Secor
    Division of Parasitic Diseases, Centers for Disease Control and Prevention, Atlanta, Georgia 30341 3724, USA
    Curr Opin Infect Dis 20:519-23. 2007
  6. ncbi request reprint Interactions between schistosomiasis and infection with HIV-1
    W E Secor
    Division of Parasitic Diseases, Centers for Disease Control and Prevention, Public Health Service, Department of Health and Human Services, Atlanta, Georgia, USA
    Parasite Immunol 28:597-603. 2006
  7. ncbi request reprint Immunology of human schistosomiasis: off the beaten path
    W E Secor
    Division of Parasitic Diseases, National Center for Infectious Diseases, Centers for Disease Control and Prevention, Public Health Service, Department of Health and Human Services, Atlanta, GA 30341 3724, USA
    Parasite Immunol 27:309-16. 2005
  8. ncbi request reprint Interactions between schistosomiasis and human immunodeficiency virus in Western Kenya
    W Evan Secor
    Division of Parasitic Diseases, Department of Health and Human Services, Public Health Service, National Center for Infectious Diseases, CDC, Atlanta, GA, USA
    Mem Inst Oswaldo Cruz 99:93-5. 2004
  9. pmc Differential Vbeta T-cell receptor usage during chronic experimental schistosomiasis corresponds with distinct pathological presentations
    W E Secor
    Immunology Branch, Division of Parasitic Diseases, National Center for Infectious Diseases, Centers for Disease Control and Prevention, U S Department of Health and Human Services, Atlanta, Georgia 30341 3724, USA
    Infect Immun 69:4177-9. 2001
  10. pmc Increased density of human immunodeficiency virus type 1 coreceptors CCR5 and CXCR4 on the surfaces of CD4(+) T cells and monocytes of patients with Schistosoma mansoni infection
    W Evan Secor
    Division of Parasitic Diseases, National Center for Infectious Diseases, Centers for Disease Control and Prevention, Public Health Service, U S Department of Health and Human Services, Atlanta, Georgia 30341, USA
    Infect Immun 71:6668-71. 2003

Collaborators

  • DANIEL COLLEY
  • J Guarner
  • T A Wynn
  • C D Funk
  • J Bruce Sundstrom
  • M Fernandez
  • Jan Mead
  • Gernot Schmid
  • Pauline N M Mwinzi
  • Diana M S Karanja
  • Maurice R Odiere
  • Z Kucerova
  • G L Freeman
  • C B CĂȘtre-Sossah
  • L M Ganley-Leal
  • H N Ehigiator
  • Kimberly Won
  • Kayla F Laserson
  • Maurice Ombok
  • Erick M Muchiri
  • Susan P Montgomery
  • Patrick J Lammie
  • Fredrick O Rawago
  • John G Ayisi
  • Erick M Muok
  • Chrispin O Owaga
  • Mariam Mwanje
  • O I Sokolova
  • M Kvac
  • B Sak
  • A V Demyanov
  • D Kvetonova
  • V H Secor
  • M T Willard
  • M A Montesano
  • N McNair
  • C W Todd
  • D A Harn
  • K Borgelt
  • A E Boyer
  • P Romagnoli
  • A A Da'Dara
  • S C Bosshardt
  • M A Brown
  • C A Gutekunst

Detail Information

Publications17

  1. ncbi request reprint Mice deficient for 5-lipoxygenase, but not leukocyte-type 12-lipoxygenase, display altered immune responses during infection with Schistosoma mansoni
    W E Secor
    Division of Parasitic Diseases, National Center for Infectious Diseases, Centers for Disease Control and Prevention, Atlanta, Georgia 30341, USA
    Prostaglandins Other Lipid Mediat 56:291-304. 1998
    ..These data suggest that 5-LO plays a role in host responses to schistosomiasis via a mechanism that cannot be explained solely by changes in expression of these cytokines...
  2. doi request reprint The effects of schistosomiasis on HIV/AIDS infection, progression and transmission
    W Evan Secor
    Division of Parasitic Diseases and Malaria, Center for Global Health, Centers for Disease Control and Prevention, Atlanta, Georgia, USA
    Curr Opin HIV AIDS 7:254-9. 2012
    ..The recent findings pertaining to the public health impact of schistosomiasis on the epidemiology of HIV/AIDS are summarized...
  3. pmc High prevalence of schistosomiasis in Mbita and its adjacent islands of Lake Victoria, western Kenya
    Maurice R Odiere
    Neglected Tropical Diseases Branch, Centre for Global Health Research, Kenya Medical Research Institute, P, O, Box 1578 40100, Kisumu, Kenya
    Parasit Vectors 5:278. 2012
    ..Consequently, there is a paucity of data on prevalence of schistosomiasis and soil-transmitted helminth (STH) infections that are endemic in this region...
  4. pmc Integrated community-directed intervention for schistosomiasis and soil transmitted helminths in western Kenya - a pilot study
    Pauline N M Mwinzi
    Center for Global Health Research, Kenya Medical Research Institute, Kisumu, Kenya
    Parasit Vectors 5:182. 2012
    ..This study evaluated the effectiveness and feasibility of the CDI strategy in the control of schistosomiasis and STHs, in East Uyoma location, Rarieda district, a community of western Kenya that is highly endemic for both infections...
  5. ncbi request reprint Below the belt: new insights into potential complications of HIV-1/schistosome coinfections
    W Evan Secor
    Division of Parasitic Diseases, Centers for Disease Control and Prevention, Atlanta, Georgia 30341 3724, USA
    Curr Opin Infect Dis 20:519-23. 2007
    ..In this review, the 'gut wrenching' consequences of schistosome infection on HIV disease progression that may ensue during coinfection are considered...
  6. ncbi request reprint Interactions between schistosomiasis and infection with HIV-1
    W E Secor
    Division of Parasitic Diseases, Centers for Disease Control and Prevention, Public Health Service, Department of Health and Human Services, Atlanta, Georgia, USA
    Parasite Immunol 28:597-603. 2006
    ....
  7. ncbi request reprint Immunology of human schistosomiasis: off the beaten path
    W E Secor
    Division of Parasitic Diseases, National Center for Infectious Diseases, Centers for Disease Control and Prevention, Public Health Service, Department of Health and Human Services, Atlanta, GA 30341 3724, USA
    Parasite Immunol 27:309-16. 2005
    ....
  8. ncbi request reprint Interactions between schistosomiasis and human immunodeficiency virus in Western Kenya
    W Evan Secor
    Division of Parasitic Diseases, Department of Health and Human Services, Public Health Service, National Center for Infectious Diseases, CDC, Atlanta, GA, USA
    Mem Inst Oswaldo Cruz 99:93-5. 2004
    ..Additional key questions with important public health implications remain unanswered, but hopefully not unanswerable...
  9. pmc Differential Vbeta T-cell receptor usage during chronic experimental schistosomiasis corresponds with distinct pathological presentations
    W E Secor
    Immunology Branch, Division of Parasitic Diseases, National Center for Infectious Diseases, Centers for Disease Control and Prevention, U S Department of Health and Human Services, Atlanta, Georgia 30341 3724, USA
    Infect Immun 69:4177-9. 2001
    ..The groups had significantly different expression of several Vbetas, suggesting a relationship between the T-cell repertoire and schistosomiasis pathology...
  10. pmc Increased density of human immunodeficiency virus type 1 coreceptors CCR5 and CXCR4 on the surfaces of CD4(+) T cells and monocytes of patients with Schistosoma mansoni infection
    W Evan Secor
    Division of Parasitic Diseases, National Center for Infectious Diseases, Centers for Disease Control and Prevention, Public Health Service, U S Department of Health and Human Services, Atlanta, Georgia 30341, USA
    Infect Immun 71:6668-71. 2003
    ..Patients with active schistosomiasis displayed higher cell surface densities of these receptors than did cured schistosomiasis patients...
  11. ncbi request reprint IL-10 deficit correlates with chronic, hypersplenomegaly syndrome in male CBA/J mice infected with Schistosoma mansoni
    S C Bosshardt
    Immunology Branch, Centers for Disease Control and Prevention, USA Public Health Service, Atlanta, GA 30341, USA
    Parasite Immunol 19:347-53. 1997
    ..This association of low levels of antigen-induced IL-10 with severe pathology is consistent with the theory that IL-10 plays a role in the immunoregulation that occurs in chronic schistosomiasis...
  12. ncbi request reprint Early responses associated with chronic pathology in murine schistosomiasis
    C B CĂȘtre-Sossah
    Division of Parasitic Diseases, Centers for Disease Control and Prevention, Public Health Service, U S Department of Health and Human Services, 4770 Buford Highway NE, Atlanta, GA 30341, USA
    Parasite Immunol 29:241-9. 2007
    ..Surprisingly, IL-10 and IFN-gamma were not correlated with CRI levels. These studies link chronic pathology to certain immunological responses during the acute phase of schistosomiasis...
  13. ncbi request reprint Comparison of Schistosoma mansoni irradiated cercariae and Sm23 DNA vaccines
    L M Ganley-Leal
    Division of Parasitic Diseases, National Center for Infectious Diseases, Centers for Disease Control and Prevention, Atlanta, Georgia 30341, USA
    Parasite Immunol 27:341-9. 2005
    ..Thus, although Sm23 DNA vaccination effectively induced parasite-specific IFN-gamma and antibody responses, it failed to evoke other critical responses needed for optimal vaccine efficacy...
  14. ncbi request reprint Mucosal cytokine and antigen-specific responses to Cryptosporidium parvum in IL-12p40 KO mice
    H N Ehigiator
    Veterans Affairs Medical Center, Decatur, Georgia, USA
    Parasite Immunol 27:17-28. 2005
    ..These observations delineate the cellular immune responses during acute C. parvum infection of the IL-12p40(-/-)mouse model...
  15. ncbi request reprint Prevalence of metronidazole-resistant Trichomonas vaginalis in a gynecology clinic
    G Schmid
    Centers for Disease Control and Prevention and Grady Memorial Hospital, Emory University School of Medicine, Atlanta, Georgia, USA
    J Reprod Med 46:545-9. 2001
    ..To determine the prevalence of in vitro resistance to metronidazole among unselected isolates of Trichomonas vaginalis and correlate in vitro findings with response to metronidazole therapy...
  16. doi request reprint Microsporidiosis and Cryptosporidiosis in HIV/AIDS Patients in St. Petersburg, Russia: Serological identification of microsporidia and Cryptosporidium parvum in sera samples from HIV/AIDS patients
    Z Kucerova
    Centers for Disease Control and Prevention, Atlanta, Georgia, USA
    AIDS Res Hum Retroviruses 27:13-5. 2011
    ..bieneusi, 4 (8.7%) for E. intestinalis, and 9 (19.6%) for E. hellem. This study is the first report to estimate the prevalence of infection with Cryptosporidium and microsporidia among Russian HIV/AIDS patients...
  17. pmc Mast cells are essential for early onset and severe disease in a murine model of multiple sclerosis
    V H Secor
    Graduate Program in Immunology and Molecular Pathogenesis, Emory University School of Medicine, Atlanta, Georgia 30322, USA
    J Exp Med 191:813-22. 2000
    ..These data provide a new mechanism for immune destruction in EAE and indicate that mast cells play a broader role in neurologic inflammation...