Research Topics
| A M RuderSummaryAffiliation: Centers for Disease Control and Prevention Country: USA Publications
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Detail Information
Publications
The Upper Midwest Health Study: gliomas and occupational exposure to chlorinated solventsAvima M Ruder
National Institute for Occupational Safety and Health, Centers for Disease Control and Prevention, Cincinnati, OH, USA
Occup Environ Med 70:73-80. 2013..Individuals with functional GST genes might convert chlorinated solvents crossing the blood-brain barrier into cytotoxic metabolites...- The Upper Midwest Health Study: industry and occupation of glioma cases and controlsAvima M Ruder
Division of Surveillance, Hazard Evaluations, and Field Studies, National Institute for Occupational Safety and Health, Cincinnati, Ohio 45226, USA
Am J Ind Med 55:747-55. 2012..Upper Midwest Health Study case-control participant work histories collected 1995-1998 were evaluated for occupational associations with glioma. "Exposures of interest" from our study protocol comprise our a priori hypotheses... 
Cytogenetic analysis of an exposed-referent study: perchloroethylene-exposed dry cleaners compared to unexposed laundry workersJames D Tucker
Department of Biological Sciences, 2117 Biological Sciences Building, 5047 Gullen Mall, Wayne State University, Detroit, MI 48202 3917, USA
Environ Health 10:16. 2011..Adverse health effects have been associated with PCE exposure. However, investigations of possible cumulative cytogenetic damage resulting from PCE exposure are lacking...- Update: cohort mortality study of workers highly exposed to polychlorinated biphenyls (PCBs) during the manufacture of electrical capacitors, 1940-1998Mary M Prince
Centers for Disease Control and Prevention, National Institute for Occupational Safety and Health, Division of Surveillance, Hazard Evaluation and Field Studies, Industrywide Studies Branch, Cincinnati, Ohio 45226, USA
Environ Health 5:13. 2006.... 
Gliomas and farm pesticide exposure in men: the upper midwest health studyAvima M Ruder
Division of Surveillance, Hazard Evaluations and Field Studies, The National Institute for Occupational Safety and Health, Centers for Disease Control and Prevention, Cincinnati, Ohio 45226, USA
Arch Environ Health 59:650-7. 2004..0. No positive association of farm pesticide exposure and glioma was found. Other farm exposures may explain the excess brain cancer risk seen in previous studies...- Potential health effects of occupational chlorinated solvent exposureAvima M Ruder
National Institute for Occupational Safety and Health, Centers for Disease Control and Prevention, Cincinnati, OH 45226, USA
Ann N Y Acad Sci 1076:207-27. 2006..The definitive studies, which should be prospective biomarker studies incorporating body burden of solvents as well as markers of effect, remain to be done... - The Upper Midwest Health Study: a case-control study of primary intracranial gliomas in farm and rural residentsA M Ruder
National Institute for Occupational Safety and Health, Mailstop R 16, 4676 Columbia Parkway, Cincinnati, OH 45226, USA
J Agric Saf Health 12:255-74. 2006..However, nonparticipation by never-farming eligible controls could have affected results. Comparisons of farm chemical exposures may clarify associations between farming and glioma that others have reported... - Exposure to farm crops, livestock, and farm tasks and risk of glioma: the Upper Midwest Health StudyAvima M Ruder
Division of Surveillance, Hazard Evaluations and Field Studies, National Institute for Occupational Safety and Health, Cincinnati, Ohio 45226, USA
Am J Epidemiol 169:1479-91. 2009..Farmers' increased risk of glioma may be due to work practices, other activities, or an inverse association with allergies (reported by other investigators)... - The NIOSH Retrospective Pesticide Reference DatabaseA M Ruder
Division of Surveillance, Hazard Evaluations, and Field Studies, National Institute for Occupational Safety and Health, Centers for Disease Control and Prevention, Cincinnati, Ohio 45226, USA
J Agric Saf Health 15:143-56. 2009..5 years) before those pesticides actually were marketed. The NIOSH-RPRD, now available to other investigators, has been a useful tool for us and other researchers to evaluate, group, and correct pesticide responses... - Mortality among workers exposed to polychlorinated biphenyls (PCBs) in an electrical capacitor manufacturing plant in Indiana: an updateAvima M Ruder
National Institute for Occupational Safety and Health, Cincinnati, Ohio 45226, USA
Environ Health Perspect 114:18-23. 2006..Melanoma mortality was not associated with estimated cumulative exposure. Brain cancer mortality did not demonstrate a clear dose-response relationship with estimated cumulative exposure... - Mortality patterns among workers exposed to styrene in the reinforced plastic boatbuilding industry: an updateAvima M Ruder
The National Institute for Occupational Safety and Health, Cincinnati, Ohio 45226, USA
Am J Ind Med 45:165-76. 2004..Mortality was updated through 1998 for 5,204 workers exposed to styrene between 1959 and 1978 at two reinforced plastic boatbuilding plants. The a priori hypothesis: leukemia and lymphoma excesses would be found... - Mortality in dry-cleaning workers: an updateA M Ruder
National Institute for Occupational Safety and Health, Cincinnati, Ohio 45226, USA
Am J Ind Med 39:121-32. 2001..Many workers also had exposure to Stoddard solvent, a petroleum-based dry-cleaning solvent... - Gliomas and farm pesticide exposure in women: the Upper Midwest Health StudyTania Carreon
Divion of Surveillance, Hazard Evaluations and Field Studies, National Institute for Occupational Safety and Health, 4676 Columbia Parkway, Cincinnati, OH 45226, USA
Environ Health Perspect 113:546-51. 2005..Results show that exposure to pesticides was not associated with an increased risk of intracranial gliomas in women. Other farm-related factors could be etiologic factors and will be discussed in future reports... - Mortality among rubber chemical manufacturing workersM M Prince
National Institute for Occupational Safety and Health NIOSH, Division of Surveillance, Hazard Evaluation, and Field Studies, Industrywide Studies Branch, 4676 Columbia Parkway, Cincinnati, Ohio 45226, USA
Am J Ind Med 37:590-8. 2000..A previous study at the plant found elevated chest pain and angina among workers in this department... - Proportionate mortality among unionized roofers and waterproofersF B Stern
Division of Surveillance, Hazard Evaluations, and Field Studies, National Institute for Occupational Safety and Health, 4676 Columbia Parkway, Cincinnati, Ohio 45226, USA
Am J Ind Med 37:478-92. 2000..Excess deaths from occupational injuries are also of concern... - Mortality and exposure response among 14,458 electrical capacitor manufacturing workers exposed to polychlorinated biphenyls (PCBs)Mary M Prince
National Institute for Occupational Safety and Health, Centers for Disease Control and Prevention, U.S. Department of Health and Human Services, Cincinnati, Ohio 45226, USA
Environ Health Perspect 114:1508-14. 2006..This is the first PCB cohort showing a strong exposure-response relationship for prostate cancer mortality... - The genetic and environmental factors involved in benzidine metabolism and bladder carcinogenesis in exposed workersTania Carreon
National Institute for Occupational Safety and Health, Cincinnati, Ohio 45226, USA
Front Biosci 11:2889-902. 2006..Additional studies and pooled analyses of existing data are needed to establish if individuals are at higher risk of bladder cancer given the presence of certain alleles that make them more susceptible to this disease... - Maternal exposure to polychlorinated biphenyls and the secondary sex ratio: an occupational cohort studyCarissa M Rocheleau
Division of Surveillance, Hazard Evaluations and Field Studies, Centers for Disease Control and Prevention, National Institute for Occupational Safety and Health, Cincinnati, Ohio, USA
Environ Health 10:20. 2011..Several studies have examined the association between environmental polychlorinated biphenyl exposure and modulations of the secondary sex ratio, with conflicting results... - NAT2 slow acetylation and bladder cancer in workers exposed to benzidineTania Carreon
Division of Surveillance, Hazard Evaluations and Field Studies, National Institute for Occupational Safety and Health, Cincinnati, OH 45226, USA
Int J Cancer 118:161-8. 2006..Study findings suggest the existence of key differences in the metabolism of mono- and diarylamines... - Biological exposure assessment to tetrachloroethylene for workers in the dry cleaning industryLauralynn T McKernan
Centers for Disease Control and Prevention CDC National Institute for Occupational Safety and Health, 4676 Columbia Parkway, R 15, Cincinnati, OH 45226, USA
Environ Health 7:12. 2008..The purpose of this study was to assess the feasibility of conducting biological tetrachloroethylene (perchloroethylene, PCE) exposure assessments of dry cleaning employees in conjunction with evaluation of possible PCE health effects... - Occupational exposure to polychlorinated biphenyls and risk of breast cancerSharon R Silver
National Institute for Occupational Safety and Health, Division of Surveillance, Hazard Evaluations and Field Studies, Cincinnati, Ohio 45226, USA
Environ Health Perspect 117:276-82. 2009..Despite the endocrine system activity exhibited by polychlorinated biphenyls (PCBs), recent studies have shown little association between PCB exposure and breast cancer mortality... - Statistical modeling of occupational chlorinated solvent exposures for case-control studies using a literature-based databaseMisty J Hein
Division of Surveillance, Hazard Evaluations and Field Studies, National Institute for Occupational Safety and Health, Cincinnati, OH 45226, USA
Ann Occup Hyg 54:459-72. 2010.... - Increased bladder cancer risk among workers exposed to o-toluidine and aniline: a reanalysisTania Carreon
Division of Surveillance, Hazard Evaluations and Field Studies, National Institute for Occupational Safety and Health, Cincinnati, Ohio, USA
Occup Environ Med 67:348-50. 2010..As additional information showed that workers in certain departments had been misclassified regarding o-toluidine exposure, we therefore conducted a reanalysis of the data using updated exposure categories... - An evaluation of retrofit engineering control interventions to reduce perchloroethylene exposures in commercial dry-cleaning shopsG Scott Earnest
Division of Applied Research and Technology, National Institute for Occupational Safety and Health, Cincinnati, Ohio, USA
Appl Occup Environ Hyg 17:104-11. 2002..Retrofit engineering controls are also likely to enable many dry-cleaning workers to lower their overall personal TWA exposures to perchloroethylene... - Effects of retrofit emission controls and work practices on perchloroethylene exposures in small dry-cleaning shopsLynda M Ewers
National Institute for Occupational Safety and Health, Cincinnati, Ohio, USA
Appl Occup Environ Hyg 17:112-20. 2002..If machines are in poor condition, a new machine or alternative technology should be considered. Shop owners and employees should never circumvent safety features on dry-cleaning machines... - Cumulative exposure estimates for polychlorinated biphenyls using a job-exposure matrixNancy Brenna Hopf
National Institute for Occupational Safety and Health NIOSH, Centers for Disease Control and Prevention, Cincinnati, OH, USA
Chemosphere 76:185-93. 2009..The purpose of this work was to develop a period-specific job-exposure matrix (JEM) for a follow-up epidemiologic study investigating the increased risks for cancer previously observed in the cohort... - Development of a retrospective job exposure matrix for PCB-exposed workers in capacitor manufacturingNancy B Hopf
Centers for Disease Control and Prevention, National Institute for Occupational Safety and Health, Division of Surveillance, Hazard Evaluation and Field Studies, Industry wide Studies Branch, USA
J Occup Health 52:199-208. 2010..A period-specific job exposure matrix (JEM) was developed for former PCB-exposed capacitor manufacturing workers (n=12,605) (1938-1977)... - Reproductive factors and risk of glioma in womenKui Huang
National Institute for Occupational Safety and Health, 4676 Columbia Parkway, Cincinnati, OH 45226, USA
Cancer Epidemiol Biomarkers Prev 13:1583-8. 2004..7; 95% confidence interval, 0.5-1.1). CONCLUSION: These results support the hypothesis that reproductive hormones play a role in the etiology of glioma among women... - Background levels of polychlorinated biphenyls in the U.S. populationNancy B Hopf
University of Cincinnati, Department of Environmental Health, Cincinnati, Ohio 45267 0056, USA
Sci Total Environ 407:6109-19. 2009..Therefore, our aim was to model serum PCB levels in the US general population over time using published data... - Indoor particles and symptoms among office workers: results from a double-blind cross-over studyMark J Mendell
National Institute for Occupational Safety and Health, Cincinnati, OH, USA
Epidemiology 13:296-304. 2002..We studied the effects of removing small airborne particles in an office building without unusual contaminant sources or occupant complaints... - Reply to the letter to the Editor: "N-Acetyltransferases and the susceptibility to benzidine-induced bladder carcinogenesis"Tania Carreon
Int J Cancer 121:1637-9; author reply 1640-1. 2007 - Polychlorinated biphenyls and neurodegenerative disease mortality in an occupational cohortKyle Steenland
Rollins School of Public Health, Emory University, 1518 Clifton Rd, Atlanta, Georgia 30322, USA
Epidemiology 17:8-13. 2006..PCBs decrease dopamine levels in rats and monkeys. Loss of dopamine is the hallmark of Parkinson disease, a neurodegenerative disease. There are no epidemiologic studies of PCBs and neurodegenerative disease...