P A Rota

Summary

Affiliation: Centers for Disease Control and Prevention
Country: USA

Publications

  1. pmc Genetic homogeneity of measles viruses associated with a measles outbreak, São Paulo, Brazil, 1997
    Maria I Oliveira
    Adolfo Lutz Institute, Sao Paulo, Brazil
    Emerg Infect Dis 8:808-13. 2002
  2. pmc Nipah virus-associated encephalitis outbreak, Siliguri, India
    Mandeep S Chadha
    National Institute of Virology, Pune, India
    Emerg Infect Dis 12:235-40. 2006
  3. pmc New measles genotype, Uganda
    Apollo Muwonge
    Uganda Virus Research Institute, Entebbe, Uganda
    Emerg Infect Dis 11:1522-6. 2005
  4. pmc Genetic characterization of Nipah virus, Bangladesh, 2004
    Brian H Harcourt
    Centers for Disease Control and Prevention, Atlanta, Georgia 30333, USA
    Emerg Infect Dis 11:1594-7. 2005
  5. doi request reprint Molecular virology of the henipaviruses
    Paul A Rota
    MS C 22, Centers for Disease Control and Prevention, Atlanta, GA 30333, USA
    Curr Top Microbiol Immunol 359:41-58. 2012
  6. pmc Adaptation to cell culture induces functional differences in measles virus proteins
    Bettina Bankamp
    Measles, Mumps, Rubella and Herpesvirus Laboratory Branch, Division of Viral Diseases, Centers for Disease Control and Prevention, MS C 22, 1600 Clifton Road, Atlanta, Georgia 30333, USA
    Virol J 5:129. 2008
  7. pmc Genetic characterization of wild-type measles viruses isolated in China, 2006-2007
    Yixin Ji
    WHO WPRO Regional Reference Measles Lab and State Key Laboratory for Molecular Virology and Genetic Engineering, National Institute for Viral Disease Control and Prevention, China Center for Disease Control and Prevention, Beijing, China
    Virol J 7:105. 2010
  8. pmc Genetic characterization of measles viruses isolated in Turkey during 2000 and 2001
    Gulay Korukluoglu
    National Measles Rubella Laboratory, Refik Saydam National Hygiene Center, Ankara, Turkey
    Virol J 2:58. 2005
  9. pmc Molecular epidemiology of measles viruses in China, 1995-2003
    Yan Zhang
    WHO Regional Reference Laboratory for Measles for the Western Pacific Region, National Institute for Viral Disease Control and Prevention, China Center for Disease Control and Prevention, Beijing 100050, China
    Virol J 4:14. 2007
  10. pmc Measles resurgence associated with continued circulation of genotype H1 viruses in China, 2005
    Yixin Ji
    WHO WPRO Regional Reference Measles Lab and State Key Laboratory for Molecular Virology and Genetic Engineering, National Institute for Viral Disease Control and Prevention, Chinese Center for Disease Control and Prevention, Beijing 100050, PR China
    Virol J 6:135. 2009

Detail Information

Publications79

  1. pmc Genetic homogeneity of measles viruses associated with a measles outbreak, São Paulo, Brazil, 1997
    Maria I Oliveira
    Adolfo Lutz Institute, Sao Paulo, Brazil
    Emerg Infect Dis 8:808-13. 2002
    ..Our findings extend the knowledge of the circulation patterns of measles virus in South America, contributing to measles control efforts in the Americas...
  2. pmc Nipah virus-associated encephalitis outbreak, Siliguri, India
    Mandeep S Chadha
    National Institute of Virology, Pune, India
    Emerg Infect Dis 12:235-40. 2006
    ..NiV infection has not been previously detected in India...
  3. pmc New measles genotype, Uganda
    Apollo Muwonge
    Uganda Virus Research Institute, Entebbe, Uganda
    Emerg Infect Dis 11:1522-6. 2005
    ..Therefore, Ugandan viruses should be considered a new, proposed genotype (d10). This new sequence information will expand the utility of molecular epidemiologic techniques for describing measles transmission patterns in eastern Africa...
  4. pmc Genetic characterization of Nipah virus, Bangladesh, 2004
    Brian H Harcourt
    Centers for Disease Control and Prevention, Atlanta, Georgia 30333, USA
    Emerg Infect Dis 11:1594-7. 2005
    ..We describe the genetic characterization of a new strain of NV isolated during outbreaks in Bangladesh (NV-B) in 2004, which confirms that NV was the etiologic agent responsible for these outbreaks...
  5. doi request reprint Molecular virology of the henipaviruses
    Paul A Rota
    MS C 22, Centers for Disease Control and Prevention, Atlanta, GA 30333, USA
    Curr Top Microbiol Immunol 359:41-58. 2012
    ..This chapter provides an overview of the molecular virology of NiV and HeV including comparisons to other, well-characterized paramyxoviruses. This chapter also describes the sequence diversity present among the henipaviruses...
  6. pmc Adaptation to cell culture induces functional differences in measles virus proteins
    Bettina Bankamp
    Measles, Mumps, Rubella and Herpesvirus Laboratory Branch, Division of Viral Diseases, Centers for Disease Control and Prevention, MS C 22, 1600 Clifton Road, Atlanta, Georgia 30333, USA
    Virol J 5:129. 2008
    ..The Vero-adapted virus (D-VI) had a mutation in the cytoplasmic tail of the hemagglutinin (H) protein...
  7. pmc Genetic characterization of wild-type measles viruses isolated in China, 2006-2007
    Yixin Ji
    WHO WPRO Regional Reference Measles Lab and State Key Laboratory for Molecular Virology and Genetic Engineering, National Institute for Viral Disease Control and Prevention, China Center for Disease Control and Prevention, Beijing, China
    Virol J 7:105. 2010
    ....
  8. pmc Genetic characterization of measles viruses isolated in Turkey during 2000 and 2001
    Gulay Korukluoglu
    National Measles Rubella Laboratory, Refik Saydam National Hygiene Center, Ankara, Turkey
    Virol J 2:58. 2005
    ..This report describes the genetic characterization of wild-type measles viruses isolated in Turkey in 2000 and 2001...
  9. pmc Molecular epidemiology of measles viruses in China, 1995-2003
    Yan Zhang
    WHO Regional Reference Laboratory for Measles for the Western Pacific Region, National Institute for Viral Disease Control and Prevention, China Center for Disease Control and Prevention, Beijing 100050, China
    Virol J 4:14. 2007
    ..This important baseline data will help to monitor the progress of measles control in China...
  10. pmc Measles resurgence associated with continued circulation of genotype H1 viruses in China, 2005
    Yixin Ji
    WHO WPRO Regional Reference Measles Lab and State Key Laboratory for Molecular Virology and Genetic Engineering, National Institute for Viral Disease Control and Prevention, Chinese Center for Disease Control and Prevention, Beijing 100050, PR China
    Virol J 6:135. 2009
    ..H1 genotype has the most inner variation within genotype, it could be divided into 2 clusters, and cluster 1 viruses were predominant in China throughout 2005...
  11. ncbi request reprint Characterization of a novel coronavirus associated with severe acute respiratory syndrome
    Paul A Rota
    National Center for Infectious Diseases, Centers for Disease Control and Prevention, Atlanta, GA 30333, USA
    Science 300:1394-9. 2003
    ..Phylogenetic analyses and sequence comparisons showed that SARS-CoV is not closely related to any of the previously characterized coronaviruses...
  12. ncbi request reprint Update on the global distribution of genotypes of wild type measles viruses
    Paul A Rota
    Measles Virus Section, National Center for Infectious Diseases, Centers for Disease Control and Prevention, Atlanta, Georgia 30333, USA
    J Infect Dis 187:S270-6. 2003
    ..This review provides updated information on the circulation patterns of measles genotypes and examples of the utility of virologic surveillance...
  13. ncbi request reprint Molecular epidemiology of measles virus
    P A Rota
    Measles, Mumps, Rubella and Herpesvirus Laboratory Branch, Centers for Disease Control and Prevention, Atlanta, GA, USA
    Curr Top Microbiol Immunol 330:129-50. 2009
    ....
  14. ncbi request reprint Genetic analysis of measles viruses isolated in the united states between 1989 and 2001: absence of an endemic genotype since 1994
    Paul A Rota
    Division of Viral and Rickettsial Diseases, National Center for Infectious Diseases, Centers for Disease Control and Prevention, Atlanta, Georgia 30333, USA
    J Infect Dis 189:S160-4. 2004
    ..Therefore, the data obtained from virological surveillance are consistent with the conclusions made by disease surveillance and epidemiological investigations that measles is no longer an endemic disease in the United States...
  15. pmc Molecular epidemiology of measles viruses in the United States, 1997-2001
    Paul A Rota
    Measles Virus Section, Centers for Disease Control and Prevention, Atlanta, Georgia 30333, USA
    Emerg Infect Dis 8:902-8. 2002
    ..Therefore, the diversity of Measles virus genotypes observed in the United States from 1997 to 2001 reflected multiple imported sources of virus and indicated that no strain of measles is endemic in the United States...
  16. doi request reprint Improving global virologic surveillance for measles and rubella
    Paul A Rota
    Centers for Disease Control and Prevention, Atlanta, Georgia 30333, USA
    J Infect Dis 204:S506-13. 2011
    ..In addition, baseline virologic surveillance, especially for rubella, needs to be improved in many countries. This report contains a summary of recent improvements to the methods used for virologic surveillance...
  17. doi request reprint Global distribution of measles genotypes and measles molecular epidemiology
    Paul A Rota
    World Health Organization WHO Global Specialized Laboratory, Atlanta, Georgia 30333, USA
    J Infect Dis 204:S514-23. 2011
    ..The future challenges will be to develop quality control programs for molecular methods and to continue to expand virologic surveillance activities in all regions...
  18. ncbi request reprint Molecular characterization of the polymerase gene and genomic termini of Nipah virus
    B H Harcourt
    Respiratory and Enteric Viruses Branch, National Center for Infectious Diseases, Centers for Disease Control and Prevention, Atlanta, Georgia 30333, USA
    Virology 287:192-201. 2001
    ..The comparison of the structures of the genomes of HV and NV is now complete and this information will help to establish the taxonomic position of these novel viruses within the family Paramyxoviridae...
  19. pmc Activity of polymerase proteins of vaccine and wild-type measles virus strains in a minigenome replication assay
    Bettina Bankamp
    Respiratory and Enteric Viruses Branch, National Center for Infectious Diseases, Centers for Disease Control and Prevention, Atlanta, Georgia 30333, USA
    J Virol 76:7073-81. 2002
    ..These data demonstrate that increased polymerase activity differentiates attenuated from wild-type viruses and suggest that functions involved in RNA synthesis contribute to the attenuated phenotype of MV vaccine strains...
  20. ncbi request reprint Molecular characterization of Nipah virus, a newly emergent paramyxovirus
    B H Harcourt
    Respiratory and Enteric Viruses Branch, Centers for Disease Control and Prevention, Atlanta, GA 30333, USA
    Virology 271:334-49. 2000
    ..Phylogenetic analysis demonstrated that although HV and NV are closely related, they are clearly distinct from any of the established genera within the Paramyxoviridae and should be considered a new genus...
  21. ncbi request reprint Monoclonal antibodies to SARS-associated coronavirus (SARS-CoV): identification of neutralizing and antibodies reactive to S, N, M and E viral proteins
    Ralph A Tripp
    National Centers for Infectious Diseases, Division of Viral and Rickettsial Diseases, Respiratory and Enteric Virus Branch, Centers for Disease Control and Prevention, 1600 Clifton Rd NE, Mailstop G 09, Atlanta, GA 30333, USA
    J Virol Methods 128:21-8. 2005
    ..The mAbs characterized should prove useful for developing SARS-CoV diagnostic assays and for studying the biology of infection and pathogenesis of disease...
  22. doi request reprint Investigation of a mumps outbreak among university students with two measles-mumps-rubella (MMR) vaccinations, Virginia, September-December 2006
    J S Rota
    National Center for Immunization and Respiratory Diseases, Centers for Disease Control and Prevention, Atlanta, Georgia 30333, USA
    J Med Virol 81:1819-25. 2009
    ..Our findings support the use of viral detection to improve laboratory diagnosis of mumps among persons who have received two doses of MMR...
  23. doi request reprint Genetic variability and mRNA editing frequencies of the phosphoprotein genes of wild-type measles viruses
    B Bankamp
    Centers for Disease Control and Prevention, Measles, Mumps, Rubella and Herpesvirus Laboratory Branch, 1600 Clifton Road, Atlanta, GA 30333, USA
    Virus Res 135:298-306. 2008
    ....
  24. ncbi request reprint Genetic characterization of contemporary wild-type measles viruses from Vietnam and the People's Republic of China: identification of two genotypes within clade H
    S L Liffick
    Division of Viral and Rickettsial Diseases, Centers for Disease Control and Prevention, 1600 Clifton Road, 30333, Atlanta, GA, USA
    Virus Res 77:81-7. 2001
    ..Sequence analysis of measles viruses imported into the United States from either China or Vietnam demonstrated that this designation of genotypes will be helpful in future measles surveillance activities...
  25. ncbi request reprint Nipah virus conforms to the rule of six in a minigenome replication assay
    Kim Halpin
    Measles Virus Section, National Center for Infectious Diseases, Centers for Disease Control and Prevention, 1600 Clifton Road, MS C22, Atlanta, GA 30333, USA
    J Gen Virol 85:701-7. 2004
    ..While these results suggest that NiV uses a replication strategy that is similar to those of other paramyxoviruses, they also support the inclusion of NiV and HeV in a separate genus within the subfamily Paramyxovirinae...
  26. ncbi request reprint Identification of naturally occurring amino acid variations that affect the ability of the measles virus C protein to regulate genome replication and transcription
    Bettina Bankamp
    Measles, Mumps, Rubella and Herpes Virus Team, Centers for Disease Control and Prevention, Mail Stop C 22, 1600 Clifton Road, Atlanta, GA 30333, USA
    Virology 336:120-9. 2005
    ..Though we did not find a link between the aa changes in MV C and attenuation, these data provide new information regarding the functions of this non-structural protein...
  27. doi request reprint Measles outbreak associated with an international youth sporting event in the United States, 2007
    Tai Ho Chen
    Epidemic Intelligence Service, Centers for Disease Control and Prevention, Atlanta, GA
    Pediatr Infect Dis J 29:794-800. 2010
    ..In 2007, the initiation of a multistate measles outbreak was associated with an imported case occurring in a participant at an international youth sporting event held in Pennsylvania...
  28. ncbi request reprint The genomic termini of wild-type and vaccine strains of measles virus
    Xin Liu
    Measles, Mumps, Rubella and Herpesvirus Branch, Centers for Disease Control and Prevention, MS C 22, 1600 Clifton Rd, Atlanta, GA 30333, USA
    Virus Res 122:78-84. 2006
    ..These results indicated that naturally occurring nucleotide variations in the 3' leader region can affect the levels of reporter protein synthesis, and presumably affected the level of replication of the virus...
  29. doi request reprint Inhibition of measles virus infections in cell cultures by peptide-conjugated morpholino oligomers
    Katrina Sleeman
    Measles, Mumps, Rubella, and Herpesviruses Laboratory Branch, Division of Viral Diseases, Centers for Disease Control and Prevention, Atlanta, GA, USA
    Virus Res 140:49-56. 2009
    ..This report provides evidence that PPMO treatment represents a promising approach for developing antiviral agents against measles and other paramyxoviruses...
  30. pmc Real-time reverse transcription-polymerase chain reaction assay for SARS-associated coronavirus
    Shannon L Emery
    Centers for Disease Control and Prevention, Atlanta, Georgia, USA
    Emerg Infect Dis 10:311-6. 2004
    ..The real-time RT-PCR assay was more sensitive than a conventional RT-PCR assay or culture isolation and proved suitable to detect SARS-CoV in clinical specimens. Application of this assay will aid in diagnosing SARS-CoV infection...
  31. doi request reprint Current status of diagnostic methods for henipavirus
    A Tamin
    Division of Viral Diseases, Centers for Disease Control and Prevention, Atlanta, GA, USA
    Dev Biol (Basel) 135:139-45. 2013
    ..This article presents a brief review on the currently available diagnostic methods for henipavirus infections, including advances achieved since the initial outbreak, and a gap analysis of areas needing improvement...
  32. pmc Spontaneous mutation rate of measles virus: direct estimation based on mutations conferring monoclonal antibody resistance
    S J Schrag
    Respiratory and Enteric Viruses Branch, National Center for Infectious Diseases, Centers for Disease Control and Prevention, Atlanta, Georgia 30033, USA
    J Virol 73:51-4. 1999
    ..In the field, however, measles virus shows marked genetic stability. We briefly discuss the evolutionary implications of these results...
  33. pmc Genetic diversity of wild-type measles viruses: implications for global measles elimination programs
    W J Bellini
    Centers for Disease Control and Prevention, Atlanta, Georgia 30333, USA
    Emerg Infect Dis 4:29-35. 1998
    ..We expect that molecular epidemiologic studies will become a powerful tool for evaluating strategies to control, eliminate, and eventually eradicate measles...
  34. ncbi request reprint Comparison of L proteins of vaccine and wild-type measles viruses
    B Bankamp
    Respiratory and Enteric Viruses Branch, National Center for Infectious Diseases, Centers for Disease Control and Prevention, Atlanta, GA 30333, USA
    J Gen Virol 80:1617-25. 1999
    ..While no set of amino acid substitutions associated consistently with wt or vaccine strains was identified, these data will provide a basis for the analysis of the activity of L proteins from vaccine and wt viruses in a functional assay...
  35. ncbi request reprint Subacute sclerosing panencephalitis: more cases of this fatal disease are prevented by measles immunization than was previously recognized
    William J Bellini
    Respiratory and Enteric Viruses Branch, National Center for Infectious Diseases, Centers for Disease Control and Prevention, Atlanta, Georgia 30333, USA
    J Infect Dis 192:1686-93. 2005
    ..The purpose of the present study was to identify cases of SSPE that were associated with the resurgence of measles and to calculate the risk of developing SSPE...
  36. pmc Detection of RNA of mumps virus during an outbreak in a population with a high level of measles, mumps, and rubella vaccine coverage
    Rebecca H Bitsko
    Epidemic Intelligence Service, Office of Workforce and Career Development, Centers for Disease Control and Prevention, Atlanta, GA 30333, USA
    J Clin Microbiol 46:1101-3. 2008
    ..Seven of the eight reverse transcription-PCR-positive specimens were collected during the first 3 days of parotitis, suggesting that viral shedding is minimal after the first 3 days of symptoms...
  37. doi request reprint Regulation of interferon signaling by the C and V proteins from attenuated and wild-type strains of measles virus
    Judith M Fontana
    Measles, Mumps, Rubella, and Herpesvirus Laboratory Branch, Centers for Disease Control and Prevention, Mailstop C 22, 1600 Clifton Road, Atlanta, Georgia 30333, USA
    Virology 374:71-81. 2008
    ....
  38. doi request reprint The C, V and W proteins of Nipah virus inhibit minigenome replication
    Katrina Sleeman
    Measles, Mumps, Rubella, and Herpesvirus Laboratory Branch, Division of Viral Diseases, Centers for Disease Control and Prevention, Atlanta, GA, USA
    J Gen Virol 89:1300-8. 2008
    ..Although there is very limited amino acid sequence similarity between the C, V and W proteins within the paramyxoviruses, the heterotypic inhibition of replication suggests that these proteins may share functional properties...
  39. ncbi request reprint Elucidation of Nipah virus morphogenesis and replication using ultrastructural and molecular approaches
    Cynthia S Goldsmith
    Division of Viral and Rickettsial Diseases, National Center for Infectious Diseases, Centers for Disease Control and Prevention, Mailstop G30, 1600 Clifton Road NE, Atlanta, GA 30333, USA
    Virus Res 92:89-98. 2003
    ..Ultrastructural ISH studies suggest these inclusions play an important role in the transcription process...
  40. pmc Target analysis of the experimental measles therapeutic AS-136A
    Jeong Joong Yoon
    Department of Pediatrics, Emory University School of Medicine and Children s Healthcare of Atlanta, Atlanta, GA 30322, USA
    Antimicrob Agents Chemother 53:3860-70. 2009
    ..Taken together, these data support the hypothesis that acquiring mutations in these L domains may reduce virus fitness...
  41. pmc Development of a neutralization assay for Nipah virus using pseudotype particles
    Azaibi Tamin
    Centers for Disease Control and Prevention, Atlanta, GA 30333, USA
    J Virol Methods 160:1-6. 2009
    ..Therefore, this new method has the potential to be a rapid and cost-effective diagnostic method, especially in locations that lack high containment facilities, and will provide a valuable tool for basic research and vaccine development...
  42. ncbi request reprint Functional properties of the fusion and attachment glycoproteins of Nipah virus
    Azaibi Tamin
    Respiratory and Enteric Viruses Branch, Centers for Disease Control and Prevention, Atlanta, Georgia 30333, USA
    Virology 296:190-200. 2002
    ..Data from these biological assays support the taxonomic grouping of both HV and NV in the new genus, Henipavirus, within the family Paramyxoviridae...
  43. doi request reprint Measles outbreak in a highly vaccinated population, San Diego, 2008: role of the intentionally undervaccinated
    David E Sugerman
    Epidemic Intelligence Service, Office of Workforce and Career Development, Centers for Disease Control and Prevention, 1600 Clifton Rd NE, Mail Stop E 05, Atlanta, GA 30333, USA
    Pediatrics 125:747-55. 2010
    ..We investigated the outbreak with the objective of understanding the effect of intentional undervaccination on measles transmission and its potential threat to measles elimination...
  44. pmc Enzyme-linked immunospot assay detection of mumps-specific antibody-secreting B cells as an alternative method of laboratory diagnosis
    Donald R Latner
    Division of Viral Diseases, National Center for Immunization and Respiratory Diseases, Centers for Disease Control and Prevention, Atlanta, GA 30333, USA
    Clin Vaccine Immunol 18:35-42. 2011
    ..In addition, it was determined that mumps-specific memory B cells are detected at a much lower frequency than measles- or rubella-specific cells, suggesting that mumps infection may not generate robust B-cell memory...
  45. ncbi request reprint Detection of measles virus RNA in whole blood stored on filter paper
    Russell S Katz
    Division of Viral and Rickettsial Diseases, National Center for Infectious Diseases, Centers for Disease Control and Prevention, Atlanta, Georgia 30333, USA
    J Med Virol 67:596-602. 2002
    ....
  46. doi request reprint Measles in the United States during the postelimination era
    Amy Parker Fiebelkorn
    Division of Viral Diseases, National Center for Immunization and Respiratory Diseases, Centers for Disease Control and Prevention, Atlanta, Georgia 30333, USA
    J Infect Dis 202:1520-8. 2010
    ..Measles affected entire birth cohorts in the prevaccine era but was declared eliminated in the United States in 2000 because of a successful measles vaccination program...
  47. ncbi request reprint Genetic changes that affect the virulence of measles virus in a rhesus macaque model
    Bettina Bankamp
    Measles, Mumps, Rubella and Herpes Viruses Laboratory Branch, Centers for Disease Control and Prevention, Atlanta, GA 30333, USA
    Virology 373:39-50. 2008
    ..These results identify a limited number of genetic changes in the genome of MV that lead to attenuation in vivo...
  48. pmc Design of a small-molecule entry inhibitor with activity against primary measles virus strains
    Richard K Plemper
    Department of Microbiology and Immunology, 3086 Rollins Research Center, 1510 Clifton Road, Emory University School of Medicine, Atlanta, GA 30322, USA
    Antimicrob Agents Chemother 49:3755-61. 2005
    ..6 to 3.0 microM, depending on the MV genotype) against a panel of wild-type MV strains representative of viruses that are currently endemic in the field...
  49. ncbi request reprint Development of quantitative gene-specific real-time RT-PCR assays for the detection of measles virus in clinical specimens
    Kimberly B Hummel
    Centers for Disease Control and Prevention, Division of Viral and Rickettsial Diseases, 1600 Clifton Road, Mailstop C 22, Atlanta, GA 30333, USA
    J Virol Methods 132:166-73. 2006
    ....
  50. ncbi request reprint Direct sequencing of SARS-coronavirus S and N genes from clinical specimens shows limited variation
    Suxiang Tong
    National Center for Infectious Diseases, Centers for Disease Control and Prevention, 1600 Clifton Road NE, MS G17, Atlanta, GA 30333, USA
    J Infect Dis 190:1127-31. 2004
    ..These findings are a part of the expanding investigation of the evolution of how this virus adapts to a new host...
  51. pmc Ultrastructural characterization of SARS coronavirus
    Cynthia S Goldsmith
    Infectious Disease Pathology Activity, Division of Viral and Rickettsial Diseases, National Center for Infectious Diseases, Centers for Disease Control and Prevention, Atlanta, Georgia 30333, USA
    Emerg Infect Dis 10:320-6. 2004
    ..Electron microscopic studies were critical in identifying the etiologic agent of the SARS outbreak and in guiding subsequent laboratory and epidemiologic investigations...
  52. ncbi request reprint Lack of evidence of measles virus shedding in people with inapparent measles virus infections
    Fabio A Lievano
    Measles Elimination Activity, Child Vaccine Preventable Diseases Branch, Epidemiology and Surveillance Division, National Immunization Program, Centers for Disease Control and Prevention, Atlanta, Georgia 30333, USA
    J Infect Dis 189:S165-70. 2004
    ..0; 95% confidence interval, 1.9-19.2). None of the 133 contacts had virological evidence of infection by culture or polymerase chain reaction. We found no evidence that persons with inapparent measles virus infections shed measles virus...
  53. ncbi request reprint Characterization of the antiviral and inflammatory responses against Nipah virus in endothelial cells and neurons
    Michael K Lo
    Measles, Mumps, Rubella, and Herpesvirus Laboratory Branch, Centers for Disease Control and Prevention, Atlanta, GA 30333, USA
    Virology 404:78-88. 2010
    ....
  54. pmc Evaluation of affymetrix severe acute respiratory syndrome resequencing GeneChips in characterization of the genomes of two strains of coronavirus infecting humans
    Irshad M Sulaiman
    Biotechnology Core Facility Branch, Scientific Resources Program, National Center for Infectious Diseases, Centers for Disease Control and Prevention, Mailstop G 36, 1600 Clifton Road, Atlanta, GA 30333, USA
    Appl Environ Microbiol 72:207-11. 2006
    ..Thus, SARS resequencing GeneChips may be employed as an alternate tool to obtain genome sequences of SARS-CoV strains pathogenic for humans in order to further understand the transmission dynamics of these viruses...
  55. ncbi request reprint Nipah virus: an emergent paramyxovirus causing severe encephalitis in humans
    William J Bellini
    Respiratory and Enteric Viruses Branch, Division of Viral and Rickettsial Diseases, National Center for Infectious Diseases, Centers for Disease Control and Prevention, Atlanta, Georgia 30333, USA
    J Neurovirol 11:481-7. 2005
    ..This review summarizes what is known about the virology, epidemiology, pathology, diagnosis and control of this novel pathogen...
  56. ncbi request reprint Incremental effectiveness of 2 doses of measles-containing vaccine compared with 1 dose among high school students during an outbreak
    Tracey V Lynn
    Alaska Division of Public Health, Anchorage, Alaska Epidemic Intelligence Service, Epidemiology Program Office, Centers for Disease Control and Prevention, Atlanta, Georgia, USA
    J Infect Dis 189:S86-90. 2004
    ..44; P<.001), yielding an estimated incremental vaccine efficacy of 94.1% (95% confidence interval, 55.9%-99.2%; P<.001). Rapid implementation of a mandatory second-dose MCV requirement probably limited the extent of this outbreak...
  57. doi request reprint The emergence of Nipah virus, a highly pathogenic paramyxovirus
    Michael K Lo
    Centers for Disease Control and Prevention, Atlanta, GA 30333, USA
    J Clin Virol 43:396-400. 2008
    ..Recent developments in diagnostics may expedite disease diagnosis and outbreak containment, while progress in understanding the molecular biology of Nipah virus could lead to novel therapeutics and vaccines for this deadly pathogen...
  58. pmc Use of monoclonal antibodies against Hendra and Nipah viruses in an antigen capture ELISA
    Cheng Feng Chiang
    Special Pathogens Branch, Division of Viral and Rickettsial Diseases, Centers for Disease Control and Prevention, Atlanta, Georgia, USA
    Virol J 7:115. 2010
    ..Outbreaks of Hendra (HeV) and Nipah (NiV) viruses have been reported starting in 1994 and 1998, respectively. Both viruses are capable of causing fatal disease in humans and effecting great economical loss in the livestock industry...
  59. pmc Identification of severe acute respiratory syndrome coronavirus replicase products and characterization of papain-like protease activity
    Brian H Harcourt
    Centers for Disease Control and Prevention, Atlanta, Georgia, USA
    J Virol 78:13600-12. 2004
    ..These studies revealed that PLpro can cleave in trans at the three predicted cleavage sites and that it requires membrane association to process the nsp3/4 cleavage site...
  60. ncbi request reprint Implications of a 2005 measles outbreak in Indiana for sustained elimination of measles in the United States
    Amy A Parker
    Epidemic Intelligence Service, Epidemiology Program Office, Centers for Disease Control and Prevention, Atlanta, GA 30333, USA
    N Engl J Med 355:447-55. 2006
    ..In 2005, a 17-year-old unvaccinated girl who was incubating measles returned from Romania, creating the largest documented outbreak of measles in the United States since 1996...
  61. doi request reprint Determination of the henipavirus phosphoprotein gene mRNA editing frequencies and detection of the C, V and W proteins of Nipah virus in virus-infected cells
    Michael K Lo
    Measles, Mumps, Rubella and Herpesviruses Laboratory Branch, Atlanta, GA 30333, USA
    J Gen Virol 90:398-404. 2009
    ..All proteins were detected in both infected cells and purified virions. In infected cells, the W protein was detected in the nucleus while P, V and C were found in the cytoplasm...
  62. ncbi request reprint The C protein of measles virus inhibits the type I interferon response
    Jessica A Shaffer
    Measles Virus Section, National Center for Infectious Diseases, Centers for Disease Control and Prevention, Atlanta, GA 30333, USA
    Virology 315:389-97. 2003
    ..While the mechanism of inhibition remains unclear, these data suggest that the MV C protein plays an important role in the pathogenesis of MV by inhibiting IFNalpha/beta signaling...
  63. doi request reprint Inhibition of interferon induction and signaling by paramyxoviruses
    Judith M Fontana
    Measles, Mumps, Rubella and Herpesvirus Laboratory Branch, Centers for Disease Control and Prevention, Emory University, Atlanta, GA 30333, USA
    Immunol Rev 225:46-67. 2008
    ..Hopefully this knowledge will support the development of more targeted vaccines and therapeutics to better prevent and control viral infection...
  64. doi request reprint Recent resurgence of mumps in the United States
    Gustavo H Dayan
    Division of Viral Diseases, National Center for Immunization and Respiratory Diseases, Centers for Disease Control and Prevention, Atlanta, GA 30333, USA
    N Engl J Med 358:1580-9. 2008
    ..S. schoolchildren beginning in 1990 was followed by historically low reports of mumps cases. A 2010 elimination goal was established, but in 2006 the largest mumps outbreak in two decades occurred in the United States...
  65. pmc Review of the temporal and geographical distribution of measles virus genotypes in the prevaccine and postvaccine eras
    Michaela A Riddell
    Department of Public Health, School of Population Health, University of Melbourne, Parkville 3010, Victoria, Australia
    Virol J 2:87. 2005
    ....
  66. ncbi request reprint Protection against challenge with measles virus (MV) in infant macaques by an MV DNA vaccine administered in the presence of neutralizing antibody
    Mary Premenko-Lanier
    California National Primate Research Center and Department of Pathology, School of Medicine, University of California, Davis, 95616, USA
    J Infect Dis 189:2064-71. 2004
    ..These results suggest that it is possible to develop an MV DNA vaccine that could protect infants in developing countries during the first months of life...
  67. ncbi request reprint Genetic analysis of measles viruses isolated in Morocco
    Amal Alla
    Institute of Health, Rabat, Morocco
    J Med Virol 68:441-4. 2002
    ..Knowledge of the indigenous strain of measles virus circulating in Morocco will help to describe viral transmission pathways and should contribute to efforts to evaluate the effectiveness of future vaccination campaigns...
  68. ncbi request reprint Genotyping of measles virus in Canada: 1979-2002
    Graham A Tipples
    Viral Exanthemata, National Microbiology Laboratory, Population and Public Health Branch, Health Canada, Winnipeg, Canada
    J Infect Dis 189:S171-6. 2004
    ....
  69. pmc Genotyping of measles virus in clinical specimens on the basis of oligonucleotide microarray hybridization patterns
    Alexander A Neverov
    Center for Biologics Evaluation and Research, Food and Drug Administration, Rockville, MD 20852 1448, USA
    J Clin Microbiol 44:3752-9. 2006
    ..In addition, the microarray demonstrated the ability to identify potential new genotypes of MV based on the similarity of their hybridization patterns with those of known MV genotypes...
  70. pmc Person-to-person transmission of Nipah virus in a Bangladeshi community
    Emily S Gurley
    Program on Infectious Diseases and Vaccine Sciences, ICDDR, B, Dhaka, Bangladesh
    Emerg Infect Dis 13:1031-7. 2007
    ..Capacity for person-to-person transmission increases the potential for wider spread of this highly lethal pathogen and highlights the need for infection control strategies for resource-poor settings...
  71. pmc High genetic diversity of measles virus, World Health Organization European Region, 2005-2006
    Jacques R Kremer
    World Health Organization WHO Regional Reference Laboratory for Measles and Rubella, Laboratoire National de Santé Immunology 20A, rue Auguste Lumiere, Luxembourg, Luxembourg
    Emerg Infect Dis 14:107-14. 2008
    ..Thus, despite the reduction of endemic MV circulation, importation of MV from other continents caused prolonged circulation and large outbreaks after their introduction into unvaccinated and highly mobile communities...
  72. doi request reprint Induction of neutralising antibodies and cellular immune responses against SARS coronavirus by recombinant measles viruses
    Matthias Liniger
    Berna Biotech a Crucell Company, Rehhagstrasse 79, CH 3018 Bern, Switzerland
    Vaccine 26:2164-74. 2008
    ..These data support the suitability of MV as a bivalent candidate vaccine vector against MV and emerging viruses such as SARS-CoV...
  73. ncbi request reprint Characterization of measles sequences from Pune, India
    Niteen Wairagkar
    National Institute of Virology, Pune, India
    J Med Virol 68:611-4. 2002
    ..Continued virologic surveillance in other areas of India as well as neighboring countries will indicate the extent of genetic diversity present among wild-type measles viruses circulating in India...
  74. doi request reprint Clinical presentation of nipah virus infection in Bangladesh
    M Jahangir Hossain
    International Centre for Diarrhoeal Disease Research, Dhaka, Bangladesh
    Clin Infect Dis 46:977-84. 2008
    ..In Bangladesh, 4 outbreaks of Nipah virus infection were identified during the period 2001-2004...
  75. doi request reprint Antibody induced by immunization with the Jeryl Lynn mumps vaccine strain effectively neutralizes a heterologous wild-type mumps virus associated with a large outbreak
    Steven A Rubin
    Division of Viral Products, Center for Biologics Evaluation and Research, United States Food and Drug Administration, Bethesda, Maryland 20892, USA
    J Infect Dis 198:508-15. 2008
    ....
  76. ncbi request reprint Genetic and antigenic characterization of measles viruses that circulated in Korea during the 2000-2001 epidemic
    Byoung Kuk Na
    Department of Virology, National Institute of Health, Seoul, Korea
    J Med Virol 70:649-54. 2003
    ....
  77. ncbi request reprint DNA vaccination of infants in the presence of maternal antibody: a measles model in the primate
    Mary Premenko-Lanier
    California National Primate Research Center and Department of Pathology, School of Medicine, University of California Davis, County Road 98, Davis, CA 95616 8542, USA
    Virology 307:67-75. 2003
    ..Further, the addition of a molecular IL-2 adjuvant augments this DNA vaccine...
  78. pmc Real-time reverse transcription-PCR assay for detection of mumps virus RNA in clinical specimens
    Jennifer D Boddicker
    University of Iowa Hygienic Laboratory, University of Iowa, 102 Oakdale Hall, H101 OH, Iowa City, IA 52242, USA
    J Clin Microbiol 45:2902-8. 2007
    ..Thus, we have developed and validated a molecular method for rapidly diagnosing mumps infection that may be used to complement existing techniques...
  79. ncbi request reprint Design and synthesis of peptidomimetic severe acute respiratory syndrome chymotrypsin-like protease inhibitors
    Arun K Ghosh
    Departments of Chemistry and Medicinal Chemistry, Purdue University, West Lafayette, IN 47907, USA
    J Med Chem 48:6767-71. 2005
    ..An X-ray crystal structure of our lead inhibitor (4) bound to SARS-3CLpro provided important drug-design templates for the design of small-molecule inhibitors...