Research Topics
Species | P A RotaSummaryAffiliation: Centers for Disease Control and Prevention Country: USA Publications
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Detail Information
Publications
Molecular virology of the henipavirusesPaul A Rota
MS C 22, Centers for Disease Control and Prevention, Atlanta, GA 30333, USA
Curr Top Microbiol Immunol 359:41-58. 2012..This chapter provides an overview of the molecular virology of NiV and HeV including comparisons to other, well-characterized paramyxoviruses. This chapter also describes the sequence diversity present among the henipaviruses...
Adaptation to cell culture induces functional differences in measles virus proteinsBettina Bankamp
Measles, Mumps, Rubella and Herpesvirus Laboratory Branch, Division of Viral Diseases, Centers for Disease Control and Prevention, MS C 22, 1600 Clifton Road, Atlanta, Georgia 30333, USA
Virol J 5:129. 2008..The Vero-adapted virus (D-VI) had a mutation in the cytoplasmic tail of the hemagglutinin (H) protein...- Genetic characterization of wild-type measles viruses isolated in China, 2006-2007Yixin Ji
WHO WPRO Regional Reference Measles Lab and State Key Laboratory for Molecular Virology and Genetic Engineering, National Institute for Viral Disease Control and Prevention, China Center for Disease Control and Prevention, Beijing, China
Virol J 7:105. 2010.... - Genetic characterization of measles viruses isolated in Turkey during 2000 and 2001Gulay Korukluoglu
National Measles Rubella Laboratory, Refik Saydam National Hygiene Center, Ankara, Turkey
Virol J 2:58. 2005..This report describes the genetic characterization of wild-type measles viruses isolated in Turkey in 2000 and 2001... - Molecular epidemiology of measles viruses in China, 1995-2003Yan Zhang
WHO Regional Reference Laboratory for Measles for the Western Pacific Region, National Institute for Viral Disease Control and Prevention, China Center for Disease Control and Prevention, Beijing 100050, China
Virol J 4:14. 2007..This important baseline data will help to monitor the progress of measles control in China... - Measles resurgence associated with continued circulation of genotype H1 viruses in China, 2005Yixin Ji
WHO WPRO Regional Reference Measles Lab and State Key Laboratory for Molecular Virology and Genetic Engineering, National Institute for Viral Disease Control and Prevention, Chinese Center for Disease Control and Prevention, Beijing 100050, PR China
Virol J 6:135. 2009..H1 genotype has the most inner variation within genotype, it could be divided into 2 clusters, and cluster 1 viruses were predominant in China throughout 2005... 
Update on the global distribution of genotypes of wild type measles virusesPaul A Rota
Measles Virus Section, National Center for Infectious Diseases, Centers for Disease Control and Prevention, Atlanta, Georgia 30333, USA
J Infect Dis 187:S270-6. 2003..This review provides updated information on the circulation patterns of measles genotypes and examples of the utility of virologic surveillance...- Characterization of a novel coronavirus associated with severe acute respiratory syndromePaul A Rota
National Center for Infectious Diseases, Centers for Disease Control and Prevention, Atlanta, GA 30333, USA
Science 300:1394-9. 2003..Phylogenetic analyses and sequence comparisons showed that SARS-CoV is not closely related to any of the previously characterized coronaviruses... - Molecular epidemiology of measles viruses in the United States, 1997-2001Paul A Rota
Measles Virus Section, Centers for Disease Control and Prevention, Atlanta, Georgia 30333, USA
Emerg Infect Dis 8:902-8. 2002..Therefore, the diversity of Measles virus genotypes observed in the United States from 1997 to 2001 reflected multiple imported sources of virus and indicated that no strain of measles is endemic in the United States... - Improving global virologic surveillance for measles and rubellaPaul A Rota
Centers for Disease Control and Prevention, Atlanta, Georgia 30333, USA
J Infect Dis 204:S506-13. 2011..In addition, baseline virologic surveillance, especially for rubella, needs to be improved in many countries. This report contains a summary of recent improvements to the methods used for virologic surveillance... - Genetic analysis of measles viruses isolated in the united states between 1989 and 2001: absence of an endemic genotype since 1994Paul A Rota
Division of Viral and Rickettsial Diseases, National Center for Infectious Diseases, Centers for Disease Control and Prevention, Atlanta, Georgia 30333, USA
J Infect Dis 189:S160-4. 2004..Therefore, the data obtained from virological surveillance are consistent with the conclusions made by disease surveillance and epidemiological investigations that measles is no longer an endemic disease in the United States... - Global distribution of measles genotypes and measles molecular epidemiologyPaul A Rota
World Health Organization WHO Global Specialized Laboratory, Atlanta, Georgia 30333, USA
J Infect Dis 204:S514-23. 2011..The future challenges will be to develop quality control programs for molecular methods and to continue to expand virologic surveillance activities in all regions... - Molecular epidemiology of measles virusP A Rota
Measles, Mumps, Rubella and Herpesvirus Laboratory Branch, Centers for Disease Control and Prevention, Atlanta, GA, USA
Curr Top Microbiol Immunol 330:129-50. 2009.... - Molecular characterization of the polymerase gene and genomic termini of Nipah virusB H Harcourt
Respiratory and Enteric Viruses Branch, National Center for Infectious Diseases, Centers for Disease Control and Prevention, Atlanta, Georgia 30333, USA
Virology 287:192-201. 2001..The comparison of the structures of the genomes of HV and NV is now complete and this information will help to establish the taxonomic position of these novel viruses within the family Paramyxoviridae... - Activity of polymerase proteins of vaccine and wild-type measles virus strains in a minigenome replication assayBettina Bankamp
Respiratory and Enteric Viruses Branch, National Center for Infectious Diseases, Centers for Disease Control and Prevention, Atlanta, Georgia 30333, USA
J Virol 76:7073-81. 2002..These data demonstrate that increased polymerase activity differentiates attenuated from wild-type viruses and suggest that functions involved in RNA synthesis contribute to the attenuated phenotype of MV vaccine strains... - Monoclonal antibodies to SARS-associated coronavirus (SARS-CoV): identification of neutralizing and antibodies reactive to S, N, M and E viral proteinsRalph A Tripp
National Centers for Infectious Diseases, Division of Viral and Rickettsial Diseases, Respiratory and Enteric Virus Branch, Centers for Disease Control and Prevention, 1600 Clifton Rd. NE, Mailstop G-09, Atlanta, GA 30333, USA
J Virol Methods 128:21-8. 2005..The mAbs characterized should prove useful for developing SARS-CoV diagnostic assays and for studying the biology of infection and pathogenesis of disease... - Genetic variability and mRNA editing frequencies of the phosphoprotein genes of wild-type measles virusesB Bankamp
Centers for Disease Control and Prevention, Measles, Mumps, Rubella and Herpesvirus Laboratory Branch, 1600 Clifton Road, Atlanta, GA 30333, USA
Virus Res 135:298-306. 2008.... - Molecular characterization of Nipah virus, a newly emergent paramyxovirusB H Harcourt
Respiratory and Enteric Viruses Branch, Centers for Disease Control and Prevention, Atlanta, GA 30333, USA
Virology 271:334-49. 2000..Phylogenetic analysis demonstrated that although HV and NV are closely related, they are clearly distinct from any of the established genera within the Paramyxoviridae and should be considered a new genus... - Identification of naturally occurring amino acid variations that affect the ability of the measles virus C protein to regulate genome replication and transcriptionBettina Bankamp
Measles, Mumps, Rubella and Herpes Virus Team, Centers for Disease Control and Prevention, Mail Stop C 22, 1600 Clifton Road, Atlanta, GA 30333, USA
Virology 336:120-9. 2005..Though we did not find a link between the aa changes in MV C and attenuation, these data provide new information regarding the functions of this non-structural protein... - Genetic characterization of Nipah virus, Bangladesh, 2004Brian H Harcourt
Centers for Disease Control and Prevention, Atlanta, Georgia 30333, USA
Emerg Infect Dis 11:1594-7. 2005..We describe the genetic characterization of a new strain of NV isolated during outbreaks in Bangladesh (NV-B) in 2004, which confirms that NV was the etiologic agent responsible for these outbreaks... - Nipah virus conforms to the rule of six in a minigenome replication assayKim Halpin
Measles Virus Section, National Center for Infectious Diseases, Centers for Disease Control and Prevention, 1600 Clifton Road, MS-C22, Atlanta, GA 30333, USA
J Gen Virol 85:701-7. 2004..While these results suggest that NiV uses a replication strategy that is similar to those of other paramyxoviruses, they also support the inclusion of NiV and HeV in a separate genus within the subfamily Paramyxovirinae... - Genetic characterization of contemporary wild-type measles viruses from Vietnam and the People's Republic of China: identification of two genotypes within clade HS L Liffick
Division of Viral and Rickettsial Diseases, Centers for Disease Control and Prevention, 1600 Clifton Road, 30333, Atlanta, GA, USA
Virus Res 77:81-7. 2001..Sequence analysis of measles viruses imported into the United States from either China or Vietnam demonstrated that this designation of genotypes will be helpful in future measles surveillance activities... - Inhibition of measles virus infections in cell cultures by peptide-conjugated morpholino oligomersKatrina Sleeman
Measles, Mumps, Rubella, and Herpesviruses Laboratory Branch, Division of Viral Diseases, Centers for Disease Control and Prevention, Atlanta, GA, USA
Virus Res 140:49-56. 2009..This report provides evidence that PPMO treatment represents a promising approach for developing antiviral agents against measles and other paramyxoviruses... - The genomic termini of wild-type and vaccine strains of measles virusXin Liu
Measles, Mumps, Rubella and Herpesvirus Branch, Centers for Disease Control and Prevention, MS-C-22, 1600 Clifton Rd, Atlanta, GA 30333, USA
Virus Res 122:78-84. 2006..These results indicated that naturally occurring nucleotide variations in the 3' leader region can affect the levels of reporter protein synthesis, and presumably affected the level of replication of the virus... - Real-time reverse transcription-polymerase chain reaction assay for SARS-associated coronavirusShannon L Emery
Centers for Disease Control and Prevention, Atlanta, Georgia, USA
Emerg Infect Dis 10:311-6. 2004..The real-time RT-PCR assay was more sensitive than a conventional RT-PCR assay or culture isolation and proved suitable to detect SARS-CoV in clinical specimens. Application of this assay will aid in diagnosing SARS-CoV infection... - Measles outbreak associated with an international youth sporting event in the United States, 2007Tai Ho Chen
Epidemic Intelligence Service, Centers for Disease Control and Prevention, Atlanta, GA
Pediatr Infect Dis J 29:794-800. 2010..In 2007, the initiation of a multistate measles outbreak was associated with an imported case occurring in a participant at an international youth sporting event held in Pennsylvania... - Genetic diversity of wild-type measles viruses: implications for global measles elimination programsW J Bellini
Centers for Disease Control and Prevention, Atlanta, Georgia 30333, USA
Emerg Infect Dis 4:29-35. 1998..We expect that molecular epidemiologic studies will become a powerful tool for evaluating strategies to control, eliminate, and eventually eradicate measles... - Spontaneous mutation rate of measles virus: direct estimation based on mutations conferring monoclonal antibody resistanceS J Schrag
Respiratory and Enteric Viruses Branch, National Center for Infectious Diseases, Centers for Disease Control and Prevention, Atlanta, Georgia 30033, USA
J Virol 73:51-4. 1999..In the field, however, measles virus shows marked genetic stability. We briefly discuss the evolutionary implications of these results... - Comparison of L proteins of vaccine and wild-type measles virusesB Bankamp
Respiratory and Enteric Viruses Branch, National Center for Infectious Diseases, Centers for Disease Control and Prevention, Atlanta, GA 30333, USA
J Gen Virol 80:1617-25. 1999..While no set of amino acid substitutions associated consistently with wt or vaccine strains was identified, these data will provide a basis for the analysis of the activity of L proteins from vaccine and wt viruses in a functional assay... - Subacute sclerosing panencephalitis: more cases of this fatal disease are prevented by measles immunization than was previously recognizedWilliam J Bellini
Respiratory and Enteric Viruses Branch, National Center for Infectious Diseases, Centers for Disease Control and Prevention, Atlanta, Georgia 30333, USA
J Infect Dis 192:1686-93. 2005..The estimated risk of developing SSPE was 10-fold higher than the previous estimate reported for the United States in 1982. CONCLUSIONS: Vaccination against measles prevents more cases of SSPE than was originally estimated... - Detection of RNA of mumps virus during an outbreak in a population with a high level of measles, mumps, and rubella vaccine coverageRebecca H Bitsko
Epidemic Intelligence Service, Office of Workforce and Career Development, Centers for Disease Control and Prevention, Atlanta, GA 30333, USA
J Clin Microbiol 46:1101-3. 2008..Seven of the eight reverse transcription-PCR-positive specimens were collected during the first 3 days of parotitis, suggesting that viral shedding is minimal after the first 3 days of symptoms... - Investigation of a mumps outbreak among university students with two measles-mumps-rubella (MMR) vaccinations, Virginia, September-December 2006J S Rota
National Center for Immunization and Respiratory Diseases, Centers for Disease Control and Prevention, Atlanta, Georgia 30333, USA
J Med Virol 81:1819-25. 2009..Our findings support the use of viral detection to improve laboratory diagnosis of mumps among persons who have received two doses of MMR... - Characterization of the antiviral and inflammatory responses against Nipah virus in endothelial cells and neuronsMichael K Lo
Measles, Mumps, Rubella, and Herpesvirus Laboratory Branch, Centers for Disease Control and Prevention, Atlanta, GA 30333, USA
Virology 404:78-88. 2010.... - Development of a neutralization assay for Nipah virus using pseudotype particlesAzaibi Tamin
Centers for Disease Control and Prevention, Atlanta, GA 30333, USA
J Virol Methods 160:1-6. 2009..Therefore, this new method has the potential to be a rapid and cost-effective diagnostic method, especially in locations that lack high containment facilities, and will provide a valuable tool for basic research and vaccine development... - Genetic changes that affect the virulence of measles virus in a rhesus macaque modelBettina Bankamp
Measles, Mumps, Rubella and Herpes Viruses Laboratory Branch, Centers for Disease Control and Prevention, Atlanta, GA 30333, USA
Virology 373:39-50. 2008..These results identify a limited number of genetic changes in the genome of MV that lead to attenuation in vivo... - Regulation of interferon signaling by the C and V proteins from attenuated and wild-type strains of measles virusJudith M Fontana
Measles, Mumps, Rubella, and Herpesvirus Laboratory Branch, Centers for Disease Control and Prevention, Mailstop C 22, 1600 Clifton Road, Atlanta, Georgia 30333, USA
Virology 374:71-81. 2008.... - The C, V and W proteins of Nipah virus inhibit minigenome replicationKatrina Sleeman
Measles, Mumps, Rubella, and Herpesvirus Laboratory Branch, Division of Viral Diseases, Centers for Disease Control and Prevention, Atlanta, GA, USA
J Gen Virol 89:1300-8. 2008..Although there is very limited amino acid sequence similarity between the C, V and W proteins within the paramyxoviruses, the heterotypic inhibition of replication suggests that these proteins may share functional properties... - Enzyme-linked immunospot assay detection of mumps-specific antibody-secreting B cells as an alternative method of laboratory diagnosisDonald R Latner
Division of Viral Diseases, National Center for Immunization and Respiratory Diseases, Centers for Disease Control and Prevention, Atlanta, GA 30333, USA
Clin Vaccine Immunol 18:35-42. 2011..In addition, it was determined that mumps-specific memory B cells are detected at a much lower frequency than measles- or rubella-specific cells, suggesting that mumps infection may not generate robust B-cell memory... - Measles in the United States during the postelimination eraAmy Parker Fiebelkorn
Division of Viral Diseases, National Center for Immunization and Respiratory Diseases, Centers for Disease Control and Prevention, Atlanta, Georgia 30333, USA
J Infect Dis 202:1520-8. 2010..Measles affected entire birth cohorts in the prevaccine era but was declared eliminated in the United States in 2000 because of a successful measles vaccination program... - Target analysis of the experimental measles therapeutic AS-136AJeong Joong Yoon
Department of Pediatrics, Emory University School of Medicine and Children s Healthcare of Atlanta, Atlanta, GA 30322, USA
Antimicrob Agents Chemother 53:3860-70. 2009..Taken together, these data support the hypothesis that acquiring mutations in these L domains may reduce virus fitness... - Evaluation of affymetrix severe acute respiratory syndrome resequencing GeneChips in characterization of the genomes of two strains of coronavirus infecting humansIrshad M Sulaiman
Biotechnology Core Facility Branch, Scientific Resources Program, National Center for Infectious Diseases, Centers for Disease Control and Prevention, Mailstop G 36, 1600 Clifton Road, Atlanta, GA 30333, USA
Appl Environ Microbiol 72:207-11. 2006..Thus, SARS resequencing GeneChips may be employed as an alternate tool to obtain genome sequences of SARS-CoV strains pathogenic for humans in order to further understand the transmission dynamics of these viruses... - Development of quantitative gene-specific real-time RT-PCR assays for the detection of measles virus in clinical specimensKimberly B Hummel
Centers for Disease Control and Prevention, Division of Viral and Rickettsial Diseases, 1600 Clifton Road, Mailstop C 22, Atlanta, GA 30333, USA
J Virol Methods 132:166-73. 2006.... - Lack of evidence of measles virus shedding in people with inapparent measles virus infectionsFabio A Lievano
Measles Elimination Activity, Child Vaccine Preventable Diseases Branch, Epidemiology and Surveillance Division, National Immunization Program, Centers for Disease Control and Prevention, Atlanta, Georgia 30333, USA
J Infect Dis 189:S165-70. 2004..0; 95% confidence interval, 1.9-19.2). None of the 133 contacts had virological evidence of infection by culture or polymerase chain reaction. We found no evidence that persons with inapparent measles virus infections shed measles virus... - Nipah virus: an emergent paramyxovirus causing severe encephalitis in humansWilliam J Bellini
Respiratory and Enteric Viruses Branch, Division of Viral and Rickettsial Diseases, National Center for Infectious Diseases, Centers for Disease Control and Prevention, Atlanta, Georgia 30333, USA
J Neurovirol 11:481-7. 2005..This review summarizes what is known about the virology, epidemiology, pathology, diagnosis and control of this novel pathogen... - Direct sequencing of SARS-coronavirus S and N genes from clinical specimens shows limited variationSuxiang Tong
National Center for Infectious Diseases, Centers for Disease Control and Prevention, 1600 Clifton Road NE, MS G17, Atlanta, GA 30333, USA
J Infect Dis 190:1127-31. 2004..These findings are a part of the expanding investigation of the evolution of how this virus adapts to a new host... - Elucidation of Nipah virus morphogenesis and replication using ultrastructural and molecular approachesCynthia S Goldsmith
Division of Viral and Rickettsial Diseases, National Center for Infectious Diseases, Centers for Disease Control and Prevention, Mailstop G30, 1600 Clifton Road NE, Atlanta, GA 30333, USA
Virus Res 92:89-98. 2003..Ultrastructural ISH studies suggest these inclusions play an important role in the transcription process... - Detection of measles virus RNA in whole blood stored on filter paperRussell S Katz
Division of Viral and Rickettsial Diseases, National Center for Infectious Diseases, Centers for Disease Control and Prevention, Atlanta, Georgia 30333, USA
J Med Virol 67:596-602. 2002.... - Functional properties of the fusion and attachment glycoproteins of Nipah virusAzaibi Tamin
Respiratory and Enteric Viruses Branch, Centers for Disease Control and Prevention, Atlanta, Georgia 30333, USA
Virology 296:190-200. 2002..Data from these biological assays support the taxonomic grouping of both HV and NV in the new genus, Henipavirus, within the family Paramyxoviridae... - Measles outbreak in a highly vaccinated population, San Diego, 2008: role of the intentionally undervaccinatedDavid E Sugerman
Epidemic Intelligence Service, Office of Workforce and Career Development, Centers for Disease Control and Prevention, 1600 Clifton Rd NE, Mail Stop E 05, Atlanta, GA 30333, USA
Pediatrics 125:747-55. 2010..We investigated the outbreak with the objective of understanding the effect of intentional undervaccination on measles transmission and its potential threat to measles elimination... - Design of a small-molecule entry inhibitor with activity against primary measles virus strainsRichard K Plemper
Department of Microbiology and Immunology, 3086 Rollins Research Center, 1510 Clifton Road, Emory University School of Medicine, Atlanta, GA 30322, USA
Antimicrob Agents Chemother 49:3755-61. 2005..6 to 3.0 microM, depending on the MV genotype) against a panel of wild-type MV strains representative of viruses that are currently endemic in the field... - Ultrastructural characterization of SARS coronavirusCynthia S Goldsmith
Infectious Disease Pathology Activity, Division of Viral and Rickettsial Diseases, National Center for Infectious Diseases, Centers for Disease Control and Prevention, Atlanta, Georgia 30333, USA
Emerg Infect Dis 10:320-6. 2004..Electron microscopic studies were critical in identifying the etiologic agent of the SARS outbreak and in guiding subsequent laboratory and epidemiologic investigations... - Incremental effectiveness of 2 doses of measles-containing vaccine compared with 1 dose among high school students during an outbreakTracey V Lynn
Alaska Division of Public Health, Anchorage, Alaska Epidemic Intelligence Service, Epidemiology Program Office, Centers for Disease Control and Prevention, Atlanta, Georgia, USA
J Infect Dis 189:S86-90. 2004..44; P<.001), yielding an estimated incremental vaccine efficacy of 94.1% (95% confidence interval, 55.9%-99.2%; P<.001). Rapid implementation of a mandatory second-dose MCV requirement probably limited the extent of this outbreak... - Identification of severe acute respiratory syndrome coronavirus replicase products and characterization of papain-like protease activityBrian H Harcourt
Centers for Disease Control and Prevention, Atlanta, Georgia, USA
J Virol 78:13600-12. 2004..These studies revealed that PLpro can cleave in trans at the three predicted cleavage sites and that it requires membrane association to process the nsp3/4 cleavage site... - Use of monoclonal antibodies against Hendra and Nipah viruses in an antigen capture ELISACheng Feng Chiang
Special Pathogens Branch, Division of Viral and Rickettsial Diseases, Centers for Disease Control and Prevention, Atlanta, Georgia, USA
Virol J 7:115. 2010..Outbreaks of Hendra (HeV) and Nipah (NiV) viruses have been reported starting in 1994 and 1998, respectively. Both viruses are capable of causing fatal disease in humans and effecting great economical loss in the livestock industry... - Implications of a 2005 measles outbreak in Indiana for sustained elimination of measles in the United StatesAmy A Parker
Epidemic Intelligence Service, Epidemiology Program Office, Centers for Disease Control and Prevention, Atlanta, GA 30333, USA
N Engl J Med 355:447-55. 2006..Maintenance of high rates of vaccination coverage, including improved strategies of communication with persons who refuse vaccination, is necessary to prevent future outbreaks and sustain the elimination of measles in the United States... - The emergence of Nipah virus, a highly pathogenic paramyxovirusMichael K Lo
Centers for Disease Control and Prevention, Atlanta, GA 30333, USA
J Clin Virol 43:396-400. 2008..Recent developments in diagnostics may expedite disease diagnosis and outbreak containment, while progress in understanding the molecular biology of Nipah virus could lead to novel therapeutics and vaccines for this deadly pathogen... - Determination of the henipavirus phosphoprotein gene mRNA editing frequencies and detection of the C, V and W proteins of Nipah virus in virus-infected cellsMichael K Lo
Measles, Mumps, Rubella and Herpesviruses Laboratory Branch, Atlanta, GA 30333, USA
J Gen Virol 90:398-404. 2009..All proteins were detected in both infected cells and purified virions. In infected cells, the W protein was detected in the nucleus while P, V and C were found in the cytoplasm... - The C protein of measles virus inhibits the type I interferon responseJessica A Shaffer
Measles Virus Section, National Center for Infectious Diseases, Centers for Disease Control and Prevention, Atlanta, GA 30333, USA
Virology 315:389-97. 2003..While the mechanism of inhibition remains unclear, these data suggest that the MV C protein plays an important role in the pathogenesis of MV by inhibiting IFNalpha/beta signaling... - Inhibition of interferon induction and signaling by paramyxovirusesJudith M Fontana
Measles, Mumps, Rubella and Herpesvirus Laboratory Branch, Centers for Disease Control and Prevention, Emory University, Atlanta, GA 30333, USA
Immunol Rev 225:46-67. 2008..Hopefully this knowledge will support the development of more targeted vaccines and therapeutics to better prevent and control viral infection... - Recent resurgence of mumps in the United StatesGustavo H Dayan
Division of Viral Diseases, National Center for Immunization and Respiratory Diseases, Centers for Disease Control and Prevention, Atlanta, GA 30333, USA
N Engl J Med 358:1580-9. 2008..S. schoolchildren beginning in 1990 was followed by historically low reports of mumps cases. A 2010 elimination goal was established, but in 2006 the largest mumps outbreak in two decades occurred in the United States... - DNA vaccination of infants in the presence of maternal antibody: a measles model in the primateMary Premenko-Lanier
California National Primate Research Center and Department of Pathology, School of Medicine, University of California-Davis, County Road 98, Davis, CA 95616-8542, USA
Virology 307:67-75. 2003..Further, the addition of a molecular IL-2 adjuvant augments this DNA vaccine... - Review of the temporal and geographical distribution of measles virus genotypes in the prevaccine and postvaccine erasMichaela A Riddell
Department of Public Health, School of Population Health, University of Melbourne, Parkville 3010, Victoria, Australia
Virol J 2:87. 2005.... - Real-time reverse transcription-PCR assay for detection of mumps virus RNA in clinical specimensJennifer D Boddicker
University of Iowa Hygienic Laboratory, University of Iowa, 102 Oakdale Hall, H101 OH, Iowa City, IA 52242, USA
J Clin Microbiol 45:2902-8. 2007..Thus, we have developed and validated a molecular method for rapidly diagnosing mumps infection that may be used to complement existing techniques... - Antibody induced by immunization with the Jeryl Lynn mumps vaccine strain effectively neutralizes a heterologous wild-type mumps virus associated with a large outbreakSteven A Rubin
Division of Viral Products, Center for Biologics Evaluation and Research, United States Food and Drug Administration, Bethesda, Maryland 20892, USA
J Infect Dis 198:508-15. 2008.... - Characterization of measles sequences from Pune, IndiaNiteen Wairagkar
National Institute of Virology, Pune, India
J Med Virol 68:611-4. 2002..Continued virologic surveillance in other areas of India as well as neighboring countries will indicate the extent of genetic diversity present among wild-type measles viruses circulating in India... - Genetic analysis of measles viruses isolated in MoroccoAmal Alla
Institute of Health, Rabat, Morocco
J Med Virol 68:441-4. 2002..Knowledge of the indigenous strain of measles virus circulating in Morocco will help to describe viral transmission pathways and should contribute to efforts to evaluate the effectiveness of future vaccination campaigns... - New measles genotype, UgandaApollo Muwonge
Uganda Virus Research Institute, Entebbe, Uganda
Emerg Infect Dis 11:1522-6. 2005..Therefore, Ugandan viruses should be considered a new, proposed genotype (d10). This new sequence information will expand the utility of molecular epidemiologic techniques for describing measles transmission patterns in eastern Africa... - Genotyping of measles virus in clinical specimens on the basis of oligonucleotide microarray hybridization patternsAlexander A Neverov
Center for Biologics Evaluation and Research, Food and Drug Administration, Rockville, MD 20852 1448, USA
J Clin Microbiol 44:3752-9. 2006..In addition, the microarray demonstrated the ability to identify potential new genotypes of MV based on the similarity of their hybridization patterns with those of known MV genotypes... - Genetic and antigenic characterization of measles viruses that circulated in Korea during the 2000-2001 epidemicByoung-Kuk Na
Department of Virology, National Institute of Health, Seoul, Korea
J Med Virol 70:649-54. 2003.... - Person-to-person transmission of Nipah virus in a Bangladeshi communityEmily S Gurley
Program on Infectious Diseases and Vaccine Sciences, ICDDR, B, Dhaka, Bangladesh
Emerg Infect Dis 13:1031-7. 2007..Capacity for person-to-person transmission increases the potential for wider spread of this highly lethal pathogen and highlights the need for infection control strategies for resource-poor settings... - Genetic homogeneity of measles viruses associated with a measles outbreak, São Paulo, Brazil, 1997Maria I Oliveira
Adolfo Lutz Institute, , Brazil
Emerg Infect Dis 8:808-13. 2002..Our findings extend the knowledge of the circulation patterns of measles virus in South America, contributing to measles control efforts in the Americas... - High genetic diversity of measles virus, World Health Organization European Region, 2005-2006Jacques R Kremer
World Health Organization WHO Regional Reference Laboratory for Measles and Rubella, Laboratoire National de Santé Immunology 20A, rue Auguste Lumiere, Luxembourg, Luxembourg
Emerg Infect Dis 14:107-14. 2008..Thus, despite the reduction of endemic MV circulation, importation of MV from other continents caused prolonged circulation and large outbreaks after their introduction into unvaccinated and highly mobile communities... - Induction of neutralising antibodies and cellular immune responses against SARS coronavirus by recombinant measles virusesMatthias Liniger
Berna Biotech a Crucell Company, Rehhagstrasse 79, CH 3018 Bern, Switzerland
Vaccine 26:2164-74. 2008..These data support the suitability of MV as a bivalent candidate vaccine vector against MV and emerging viruses such as SARS-CoV... - Genotyping of measles virus in Canada: 1979-2002Graham A Tipples
Viral Exanthemata, National Microbiology Laboratory, Population and Public Health Branch, Health Canada, Winnipeg, Canada
J Infect Dis 189:S171-6. 2004.... - Protection against challenge with measles virus (MV) in infant macaques by an MV DNA vaccine administered in the presence of neutralizing antibodyMary Premenko-Lanier
California National Primate Research Center and Department of Pathology, School of Medicine, University of California, Davis, 95616, USA
J Infect Dis 189:2064-71. 2004..These results suggest that it is possible to develop an MV DNA vaccine that could protect infants in developing countries during the first months of life... - Clinical presentation of nipah virus infection in BangladeshM Jahangir Hossain
International Centre for Diarrhoeal Disease Research, Dhaka, Bangladesh
Clin Infect Dis 46:977-84. 2008..In Bangladesh, 4 outbreaks of Nipah virus infection were identified during the period 2001-2004... - Nipah virus-associated encephalitis outbreak, Siliguri, IndiaMandeep S Chadha
National Institute of Virology, Pune, India
Emerg Infect Dis 12:235-40. 2006..NiV infection has not been previously detected in India... - Design and synthesis of peptidomimetic severe acute respiratory syndrome chymotrypsin-like protease inhibitorsArun K Ghosh
Departments of Chemistry and Medicinal Chemistry, Purdue University, West Lafayette, IN 47907, USA
J Med Chem 48:6767-71. 2005..An X-ray crystal structure of our lead inhibitor (4) bound to SARS-3CLpro provided important drug-design templates for the design of small-molecule inhibitors...