Research Topics
| Jeffrey S ReynoldsSummaryAffiliation: Centers for Disease Control and Prevention Country: USA Publications
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Detail Information
Publications
Nonlinear model for offline correction of pulmonary waveform generatorsJeffrey S Reynolds
Engineering and Controls Technology Branch, Health Effects Laboratory Division, National Institute for Occupational Safety and Health, Morgantown, WV 26505, USA
IEEE Trans Biomed Eng 49:1567-73. 2002..0%. When loaded with the Micro DiaryCard meter, the uncorrected pump outputs included six waveforms with MSE higher than 0.001 L2/s2. Pump corrections for these six waveforms resulted in a mean decrease in MSE of 58.4%...
Noninvasive pulmonary function screening in spontaneously breathing rodents: an engineering systems perspectiveJeffrey S Reynolds
Pathology and Physiology Research Branch, National Institute for Occupational Safety and Health, Centers for Disease Control and Prevention, 1095 Willowdale Road, Morgantown, WV 26505, USA
Pharmacol Ther 131:359-68. 2011..This model is used as a basis to demonstrate the relationship between pulmonary parameters derived from circuit analysis...
Pulmonary effects after acute inhalation of oil dispersant (COREXIT EC9500A) in ratsJenny R Roberts
Health Effects Laboratory Division, National Institute for Occupational Safety and Health, Morgantown, West Virginia 26505, USA
J Toxicol Environ Health A 74:1381-96. 2011..COREXIT inhibited neurogenic contractile responses of strips to electrical field stimulation. Our findings suggest that COREXIT inhalation did not initiate lung inflammation, but may transiently increase the difficulty of breathing...
Model predictions of the recruitment of lung units and the lung surface area-volume relationship during inflationDavid G Frazer
Health Effects Laboratory Division, National Institute for Occupational Safety and Health, Morgantown, WV 26505, USA
Ann Biomed Eng 32:756-63. 2004..86 and 1. This result supports the theory that, for inflation from EEPs below 4 cmH2O, lung expansion occurs in part by the recruitment of lung units and not solely by the expansion of open units...
Unrestrained acoustic plethysmograph for measuring specific airway resistance in miceJeffrey S Reynolds
Pathology and Physiology Research Branch, Health Effects Laboratory Division, National Institute for Occupational Safety and Health, 1095 Willowdale Rd, ms L2101, Morgantown, WV 26505, USA
J Appl Physiol 105:711-7. 2008..s. A dose-dependent increase in sRaw was shown, with an approximate tripling of sRaw at the highest dose. These results demonstrate the ability of the system to estimate sRaw based on plethysmograph airflow and acoustic amplitude...
Effects of titanium dioxide nanoparticle exposure on neuroimmune responses in rat airwaysMario Scuri
Department of Pediatrics, West Virginia University School of Medicine, Morgantown, West Virginia 26506, USA
J Toxicol Environ Health A 73:1353-69. 2010..These results suggest the presence of a critical window of vulnerability in earlier stages of lung development, which may lead to a higher risk of developing asthma...
Determining when enhanced pause (Penh) is sensitive to changes in specific airway resistanceDavid G Frazer
Pathology and Physiology Research Branch, Health Effects Laboratory Division, National Institute for Occupational Safety and Health, Morgantown, West Virginia 26505, USA
J Toxicol Environ Health A 74:287-95. 2011..That relationship is used to describe the conditions under which whole-body plethysmograph Penh measurements can be used to detect changes in sRaw...
Dispersion and exposure to a cough-generated aerosol in a simulated medical examination roomWilliam G Lindsley
National Institute for Occupational Safety and Health, Health Effects Laboratory Division, 1095 Willowdale Road, Morgantown, WV 26505 2845, USA
J Occup Environ Hyg 9:681-90. 2012....
Inhalation of ortho-phthalaldehyde vapor causes respiratory sensitization in miceVictor J Johnson
Toxicology and Molecular Biology Branch, Health Effects Laboratory Division, National Institute for Occupational Safety and Health, Centers for Disease Control and Prevention, Morgantown, WV 26505 2888, USA
J Allergy (Cairo) 2011:751052. 2011..Mice exposed to the higher concentrations of OPA-produced OPA-specific IgG(1) antibodies indicating systemic sensitization. These findings provide evidence that OPA has the potential to cause respiratory sensitization in mice...
Unrestrained acoustic plethysmograph for measuring tidal volume in miceJeffrey S Reynolds
Pathology and Physiology Research Branch, Health Effects Laboratory Division, National Institute for Occupational Safety and Health, Morgantown, WV 26505, USA
Ann Biomed Eng 34:1494-9. 2006..The RMS error between measured and delivered volume was 4.43 microL. A volume step test, performed to assess the response time of the system, showed that the plethysmograph responded in less than one millisecond...
Metal working fluids: sub-chronic effects on pulmonary functions in B6C3F1 mice given vitamin E deficient and sufficient dietsAnna A Shvedova
Pathology and Physiology Research Branch, Engineering Control and Technology Branch, National Institute for Occupational Safety and Health, Centers for Disease Control and Prevention, Morgantown, WV 26505, USA
Toxicology 177:285-97. 2002..This is the first report that describes the increase of oxidative stress in the lungs after MWF exposure...
