Michael A Purdy

Summary

Affiliation: Centers for Disease Control and Prevention
Country: USA

Publications

  1. pmc Hepatitis B virus S gene escape mutants
    Michael A Purdy
    Division of Viral Hepatitis, MS A33, Centers for Disease Control and Prevention, 1600 Clifton Rd NE, Atlanta, GA 30329, USA
    Asian J Transfus Sci 1:62-70. 2007
  2. pmc The hepatitis E virus polyproline region is involved in viral adaptation
    Michael A Purdy
    Centers for Disease Control and Prevention, National Center for HIV Hepatitis STD TB Prevention, Division of Viral Hepatitis, Atlanta, Georgia, United States of America
    PLoS ONE 7:e35974. 2012
  3. pmc Evolutionary history and population dynamics of hepatitis E virus
    Michael A Purdy
    Division of Viral Hepatitis, Centers for Disease Control and Prevention, Atlanta, Georgia, United States of America
    PLoS ONE 5:e14376. 2010
  4. doi request reprint The molecular epidemiology of hepatitis E virus infection
    Michael A Purdy
    Centers for Disease Control and Prevention, National Center for HIV Hepatitis STD TB Prevention, Division of Viral Hepatitis, Atlanta, GA 30333, USA
    Virus Res 161:31-9. 2011
  5. doi request reprint Supragenotypic groups of the hepatitis B virus genome
    Michael A Purdy
    Division of Viral Hepatitis, MS A33, Centers for Disease Control and Prevention, 1600 Clifton Road NE, Atlanta, GA 30329 4018, USA
    J Gen Virol 89:1179-83. 2008
  6. pmc Evolution of the hepatitis E virus polyproline region: order from disorder
    Michael A Purdy
    Centers for Disease Control and Prevention, Office of Infectious Diseases, National Center for HIV Hepatitis STD TB Prevention, Division of Viral Hepatitis, MS A33, Atlanta, Georgia, USA
    J Virol 86:10186-93. 2012
  7. doi request reprint Epidemic history of hepatitis C virus infection in two remote communities in Nigeria, West Africa
    Joseph C Forbi
    Molecular Epidemiology and Bioinformatics Laboratory, Division of Viral Hepatitis, Centers for Disease Control and Prevention, Atlanta, GA 30333, USA
    J Gen Virol 93:1410-21. 2012
  8. pmc Temporal variations in the hepatitis C virus intrahost population during chronic infection
    Sumathi Ramachandran
    Molecular Epidemiology and Bioinformatics Laboratory, Division of Viral Hepatitis, Centers for Disease Control and Prevention, 1600 Clifton Rd, Atlanta, GA 30333, USA
    J Virol 85:6369-80. 2011
  9. doi request reprint Intra-host diversity and evolution of hepatitis C virus endemic to Côte d'Ivoire
    Joseph C Forbi
    Division of Viral Hepatitis, National Center for HIV, Hepatitis, STD, and TB Prevention, Centers for Disease Control and Prevention, Atlanta, Georgia
    J Med Virol 86:765-71. 2014
  10. pmc Epidemic history and evolutionary dynamics of hepatitis B virus infection in two remote communities in rural Nigeria
    Joseph C Forbi
    Division of Viral Hepatitis, Centers for Disease Control and Prevention, Atlanta, Georgia, United States of America
    PLoS ONE 5:e11615. 2010

Collaborators

Detail Information

Publications16

  1. pmc Hepatitis B virus S gene escape mutants
    Michael A Purdy
    Division of Viral Hepatitis, MS A33, Centers for Disease Control and Prevention, 1600 Clifton Rd NE, Atlanta, GA 30329, USA
    Asian J Transfus Sci 1:62-70. 2007
    ..The inability to detect occult infections means that these individuals may become blood donors. This suggests that new strategies for donor evaluation and selection may need to be developed to protect the blood supply...
  2. pmc The hepatitis E virus polyproline region is involved in viral adaptation
    Michael A Purdy
    Centers for Disease Control and Prevention, National Center for HIV Hepatitis STD TB Prevention, Division of Viral Hepatitis, Atlanta, Georgia, United States of America
    PLoS ONE 7:e35974. 2012
    ..Particularly as an IDR, the PPR likely contributes to fine tuning of viral replication through protein-protein interactions and should be considered as a target for development of novel anti-viral drugs...
  3. pmc Evolutionary history and population dynamics of hepatitis E virus
    Michael A Purdy
    Division of Viral Hepatitis, Centers for Disease Control and Prevention, Atlanta, Georgia, United States of America
    PLoS ONE 5:e14376. 2010
    ..It has been suggested that hepatitis E is zoonotic, but no study has analyzed the evolutionary history of HEV. We present here an analysis of the evolutionary history of HEV...
  4. doi request reprint The molecular epidemiology of hepatitis E virus infection
    Michael A Purdy
    Centers for Disease Control and Prevention, National Center for HIV Hepatitis STD TB Prevention, Division of Viral Hepatitis, Atlanta, GA 30333, USA
    Virus Res 161:31-9. 2011
    ..The rate and mechanisms of human-to-human transmission and zoonotic transmission to humans vary geographically, thus contributing to the complexity of HEV molecular evolution...
  5. doi request reprint Supragenotypic groups of the hepatitis B virus genome
    Michael A Purdy
    Division of Viral Hepatitis, MS A33, Centers for Disease Control and Prevention, 1600 Clifton Road NE, Atlanta, GA 30329 4018, USA
    J Gen Virol 89:1179-83. 2008
    ..Present-day genotype G is postulated to be a recombinant with the non-polymerase region of group III virus and the polymerase gene of an ancestral virus belonging to group I...
  6. pmc Evolution of the hepatitis E virus polyproline region: order from disorder
    Michael A Purdy
    Centers for Disease Control and Prevention, Office of Infectious Diseases, National Center for HIV Hepatitis STD TB Prevention, Division of Viral Hepatitis, MS A33, Atlanta, Georgia, USA
    J Virol 86:10186-93. 2012
    ....
  7. doi request reprint Epidemic history of hepatitis C virus infection in two remote communities in Nigeria, West Africa
    Joseph C Forbi
    Molecular Epidemiology and Bioinformatics Laboratory, Division of Viral Hepatitis, Centers for Disease Control and Prevention, Atlanta, GA 30333, USA
    J Gen Virol 93:1410-21. 2012
    ..The data suggest a massive introduction of numerous HCV variants to the communities during the 20th century in the background of a dynamic evolutionary history of the hepatitis C epidemic in Nigeria over the past three centuries...
  8. pmc Temporal variations in the hepatitis C virus intrahost population during chronic infection
    Sumathi Ramachandran
    Molecular Epidemiology and Bioinformatics Laboratory, Division of Viral Hepatitis, Centers for Disease Control and Prevention, 1600 Clifton Rd, Atlanta, GA 30333, USA
    J Virol 85:6369-80. 2011
    ..The data suggest specific staging of HCV intrahost evolution...
  9. doi request reprint Intra-host diversity and evolution of hepatitis C virus endemic to Côte d'Ivoire
    Joseph C Forbi
    Division of Viral Hepatitis, National Center for HIV, Hepatitis, STD, and TB Prevention, Centers for Disease Control and Prevention, Atlanta, Georgia
    J Med Virol 86:765-71. 2014
    ..Collectively, the results indicate a complex HCV evolution in Côte d'Ivoire, similar to the rest of West Africa, and suggest a unique HCV epidemic history in the country...
  10. pmc Epidemic history and evolutionary dynamics of hepatitis B virus infection in two remote communities in rural Nigeria
    Joseph C Forbi
    Division of Viral Hepatitis, Centers for Disease Control and Prevention, Atlanta, Georgia, United States of America
    PLoS ONE 5:e11615. 2010
    ..It was expected that only a few, if any, HBV strains could have been introduced and effectively transmitted among these residents, reflecting limited contacts of these communities with the general population in the country...
  11. doi request reprint Hepatitis A virus: host interactions, molecular epidemiology and evolution
    Gilberto Vaughan
    Division of Viral Hepatitis, Centers for Disease Control and Prevention, Atlanta, GA, United States Electronic address
    Infect Genet Evol 21:227-43. 2014
    ..Here, we present up-to-date information on the HAV molecular epidemiology and evolution, and highlight the most relevant features of the HAV-host interactions. ..
  12. pmc Genetic relatedness among hepatitis A virus strains associated with food-borne outbreaks
    Gilberto Vaughan
    Division of Viral Hepatitis, Centers for Diseases Control and Prevention, Atlanta, Georgia, United States of America
    PLoS ONE 8:e74546. 2013
    ..Thus, accurate tracking of HAV strains can be accomplished using HAV WG sequences, while short subgenomic regions are useful for identification of transmissions only among cases with known epidemiological association. ..
  13. ncbi request reprint Genetic host specificity of hepatitis E virus
    James Lara
    Division of Viral Hepatitis, Centers for Disease Control and Prevention, Atlanta, GA, USA Electronic address
    Infect Genet Evol 24:127-39. 2014
    ....
  14. ncbi request reprint A new algorithm for deduction of hepatitis B surface antigen subtype determinants from the amino acid sequence
    Michael A Purdy
    Division of Viral Hepatitis, National Center for Infectious Diseases, Centers for Disease Control and Prevention, Atlanta, GA 30333, USA
    Intervirology 50:45-51. 2007
    ..We have reexamined hepatitis B virus subtypes to determine the role of specific HBsAg amino acids in serologic reactivity because of problematic genotype/subtype associations seen in a set of geographically diverse serum specimens...
  15. pmc Restricted enzooticity of hepatitis E virus genotypes 1 to 4 in the United States
    Chen Dong
    Division of Viral Hepatitis, Centers for Disease Control and Prevention, Atlanta, Georgia, USA
    J Clin Microbiol 49:4164-72. 2011
    ..HEV infected farmed swine primarily, and the role of other animals as reservoirs of its zoonotic spread appears to be limited...