Research Topics
| Ann M PowersSummaryAffiliation: Centers for Disease Control and Prevention Country: USA Publications
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Detail Information
Publications
Genomic evolution and phenotypic distinctions of Chikungunya viruses causing the Indian Ocean outbreakAnn M Powers
Division of Vector Borne Infectious Diseases, Centers for Disease Control and Prevention, 3150 Rampart Road, Fort Collins, CO 80521, USA
Exp Biol Med (Maywood) 236:909-14. 2011..This review will highlight some of the most significant recent research developments obtained using these cutting edge approaches for CHIKV...
Changing patterns of chikungunya virus: re-emergence of a zoonotic arbovirusAnn M Powers
Division of Vector-Borne Infectious Diseases, Centers for Disease Control and Prevention, 3150 Rampart Road, Fort Collins, CO 80521, USA
J Gen Virol 88:2363-77. 2007
Genetic relationships among Mayaro and Una viruses suggest distinct patterns of transmissionAnn M Powers
Centers for Disease Control and Prevention, Division of Vector Borne Infectious Diseases, Fort Collins, Colorado 80522, USA
Am J Trop Med Hyg 75:461-9. 2006..These analyses provide possible explanations for the natural ecology and transmission of MAYV and UNAV...
ChikungunyaAnn M Powers
Centers for Disease Control and Prevention, Fort Collins, CO 80521, USA
Clin Lab Med 30:209-19. 2010..A discussion of the virus, its epidemiology, diagnostic criteria, and immunity are presented in this article...
Treatment with cationic liposome-DNA complexes (CLDCs) protects mice from lethal Western equine encephalitis virus (WEEV) challengeChristopher H Logue
Division of Vector Borne Infectious Diseases, Centers for Disease Control, Fort Collins, CO 80521, USA
Antiviral Res 87:195-203. 2010....
Chikungunya virus: possible impact on transfusion medicineLyle R Petersen
Division of Vector Borne Infectious Diseases, Centers for Disease Control and Prevention, Fort Collins, CO 80521, USA
Transfus Med Rev 24:15-21. 2010..Assays suitable for testing donations for CHIKV RNA are not yet available, and given the highly geographically and temporally sporadic nature of CHIKV outbreaks, there may be considerable reluctance to develop and implement them...
Japanese encephalitis virus remains an important cause of encephalitis in ThailandSonja J Olsen
Divison of Emerging Infections and Surveillance Services, Centers for Disease Control and Prevention Collaboration, 1600 Clifton Road, MS C 12, Atlanta, GA 30333, USA
Int J Infect Dis 14:e888-92. 2010..Japanese encephalitis virus (JEV) is endemic in Thailand and prevention strategies include vaccination, vector control, and health education...
West Nile virus-infected mosquitoes, Louisiana, 2002Marvin S Godsey
Division of Vector Borne Infectious Diseases, Centers for Disease Control and Prevention, Fort Collins, Colorado 80522, USA
Emerg Infect Dis 11:1399-404. 2005..Mosquito infection rates among sites ranged from 0.8/1,000 to 10.9/1,000. Results suggest that Cx. quinquefasciatus was the primary epizootic/epidemic vector, with other species possibly playing a secondary role...
O'nyong nyong virus molecular determinants of unique vector specificity reside in non-structural protein 3Kali D Saxton-Shaw
Division of Vector Borne Infectious Diseases, Centers for Disease Control and Prevention, Fort Collins, Colorado, United States of America
PLoS Negl Trop Dis 7:e1931. 2013..5%. No other single gene or viral region addition was able to restore infection rates. Thus, we have shown that a non-structural genome element involved in viral replication is a major element involved in ONNV's unique vector specificity...
Evaluation of widely used diagnostic tests to detect West Nile virus infections in horses previously infected with St. Louis encephalitis virus or dengue virus type 2Jeremy P Ledermann
Centers for Disease Control and Prevention, Division of Vector Borne Infectious Diseases, 3150 Rampart Road, Fort Collins, CO 80521, USA
Clin Vaccine Immunol 18:580-7. 2011..Of great importance, we demonstrated that timing of sample collection and the need for multiple samples are important, as the infecting etiology could be misdiagnosed if only a single sample is tested...
Zika virus outbreak on Yap Island, Federated States of MicronesiaMark R Duffy
Division of Vector Borne Infectious Diseases, National Center for Zoonotic, Vector Borne, and Enteric Diseases, Centers for Disease Control and Prevention, Fort Collins, CO 80521, USA
N Engl J Med 360:2536-43. 2009..No previous outbreaks and only 14 cases of Zika virus disease have been previously documented...
Chikungunya fever: an epidemiological review of a re-emerging infectious diseaseJ Erin Staples
Arboviral Diseases Branch, Division of Vector Borne Infectious Diseases, Centers for Disease Control and Prevention, Fort Collins, Colorado 80521, USA
Clin Infect Dis 49:942-8. 2009....
Virulence variation among isolates of western equine encephalitis virus in an outbred mouse modelChristopher H Logue
Division of Vector Borne Infectious Diseases, Centers for Disease Control and Prevention, Fort Collins, CO 80521, USA
J Gen Virol 90:1848-58. 2009....
Removal of species constraints in antibody detectionAlison Jane Basile
Division of Vector Borne Infectious Diseases, Centers for Disease Control and Prevention, 3150 Rampart Rd, Fort Collins, CO 80521, USA
Clin Vaccine Immunol 17:56-61. 2010..Agent-specific adaptations of this simple format should facilitate expanded surveillance and diagnostic capabilities regarding pathogens of human and veterinary importance...
Effects of an opal termination codon preceding the nsP4 gene sequence in the O'Nyong-Nyong virus genome on Anopheles gambiae infectivityKevin M Myles
Division of Vector Borne Infectious Diseases, Centers for Disease Control and Prevention, Fort Collins, CO, USA
J Virol 80:4992-7. 2006..Taken together, these results suggest that the primary fitness advantage provided to ONNV by the presence of an opal codon between nsP3 and nsP4 is related to mosquito infectivity...
Entomologic investigations of a chikungunya virus epidemic in the Union of the Comoros, 2005Rosemary C Sang
Kenya Medical Research Institute, Nairobi, Kenya
Am J Trop Med Hyg 78:77-82. 2008..This was supported by high container (31.1%), household (68%), and Breteau (126) indices, with discarded tires (58.8%) and small cooking and water storage vessels (31.1%) registering the highest container indices...
A single positively selected West Nile viral mutation confers increased virogenesis in American crowsAaron C Brault
Center for Vector Borne Diseases and Department of Pathology, Microbiology and Immunology, School of Veterinary Medicine, University of California, Davis, California 95616, USA
Nat Genet 39:1162-6. 2007..These phenotypic and evolutionary results provide compelling evidence for the positive selection of a mutation encoding increased viremia potential and virulence in the AMCR sentinel bird species...
Glycosaminoglycan binding properties of natural venezuelan equine encephalitis virus isolatesEryu Wang
Center for Tropical Diseases and Department of Pathology, University of Texas Medical Branch, Galveston 77555-0609, USA
J Virol 77:1204-10. 2003....
Differential infectivities of o'nyong-nyong and chikungunya virus isolates in Anopheles gambiae and Aedes aegypti mosquitoesDana L Vanlandingham
Department of Pathology, University of Texas Medical Branch, Galveston, Texas 77555-0609, USA
Am J Trop Med Hyg 72:616-21. 2005..gambiae and Ae. aegypti. The species specificity in vivo was reflected by in vitro experiments using culicine and anopheline-derived cell lines...
Drought-associated chikungunya emergence along coastal East AfricaJean Paul Chretien
Department of Defense Global Emerging Infections Surveillance and Response System DoD GEIS, Walter Reed Army Institute of Research, Silver Spring, Maryland 20910 7500, USA
Am J Trop Med Hyg 76:405-7. 2007..These results suggest that drought-affected populations may be at heightened risk for chikungunya fever, and underscore the need for safe water storage during drought relief operations...
Recombinant alphaviruses are safe and useful serological diagnostic toolsHaolin Ni
Center for Biodefense and Emerging Infectious Diseases, Department of Pathology, University of Texas Medical Branch, Galveston, Texas 77555, USA
Am J Trop Med Hyg 76:774-81. 2007..Chimeric viruses were produced efficiently in cell culture and were as effective as the parental virus for identifying infection of humans, horses, and rodents in these serological assays...
West Nile virus in horses, GuatemalaMaria Eugenia Morales-Betoulle
Emerg Infect Dis 12:1038-9. 2006
Seroprevalence of Chikungunya virus infection on Grande Comore Island, union of the Comoros, 2005Kibet Sergon
Epidemiology and Laboratory Training Program, Nairobi, Kenya Ministry of Health, Moroni, Comoros
Am J Trop Med Hyg 76:1189-93. 2007..The findings suggest that CHIKV was broadly transmitted during the outbreak with a high attack rate. Although not fatal during this outbreak, CHIKV infection caused significant morbidity and decreased economic productivity...
Short report: serological evidence of West Nile virus activity in El SalvadorLilian Cruz
Field Epidemiology Training Program, Ministry of Public Health and Social Welfare, San Salvador, El Salvador
Am J Trop Med Hyg 72:612-5. 2005..Ten of these infections were confirmed by plaque reduction neutralization tests, suggesting West Nile virus has extended its range and spread to Central America...
Venezuelan equine encephalitis emergence: enhanced vector infection from a single amino acid substitution in the envelope glycoproteinAaron C Brault
Center for Biodefense and Emerging Infectious Diseases and Department of Pathology, University of Texas Medical Branch, Galveston, TX 77555-0609, USA
Proc Natl Acad Sci U S A 101:11344-9. 2004..Our findings underscore the capacity of RNA viruses to alter their vector host range through minor genetic changes, resulting in the potential for disease emergence...
Serologic survey of domestic animals for zoonotic arbovirus infections in the Lacandón Forest region of Chiapas, MexicoArmando Ulloa
, Tapachula, Chiapas, Mexico
Vector Borne Zoonotic Dis 3:3-9. 2003..There was no evidence for transmission of the other viruses (ROC, ILH, EEE, WEE) in the study area...
Arbovirus evolution in vivo is constrained by host alternationLark L Coffey
Department of Pathology and Center for Tropical Diseases, University of Texas Medical Branch, Galveston, TX 77555, USA
Proc Natl Acad Sci U S A 105:6970-5. 2008..These results suggest that arbovirus adaptation and evolution is limited by obligate host alternation and predict that arboviral emergence via host range changes may be less frequent than that of single host animal RNA viruses...
Vector infection determinants of Venezuelan equine encephalitis virus reside within the E2 envelope glycoproteinAaron C Brault
Center for Tropical Diseases and Department of Pathology, University of Texas Medical Branch, Galveston, Texas 77555-0609, USA
J Virol 76:6387-92. 2002....
Positively charged amino acid substitutions in the e2 envelope glycoprotein are associated with the emergence of venezuelan equine encephalitis virusAaron C Brault
Center for Tropical Diseases and Department of Pathology, University of Texas Medical Branch, Galveston, Texas 77555-0609, USA
J Virol 76:1718-30. 2002..Maximum-likelihood analysis indicated that one change at E2 position 213 has been influenced by positive selection and convergent evolution of the epizootic phenotype...
