Ann M Powers

Summary

Affiliation: Centers for Disease Control and Prevention
Country: USA

Publications

  1. ncbi request reprint Genomic evolution and phenotypic distinctions of Chikungunya viruses causing the Indian Ocean outbreak
    Ann M Powers
    Division of Vector Borne Infectious Diseases, Centers for Disease Control and Prevention, 3150 Rampart Road, Fort Collins, CO 80521, USA
    Exp Biol Med (Maywood) 236:909-14. 2011
  2. pmc O'nyong nyong virus molecular determinants of unique vector specificity reside in non-structural protein 3
    Kali D Saxton-Shaw
    Division of Vector Borne Infectious Diseases, Centers for Disease Control and Prevention, Fort Collins, Colorado, United States of America
    PLoS Negl Trop Dis 7:e1931. 2013
  3. ncbi request reprint Changing patterns of chikungunya virus: re-emergence of a zoonotic arbovirus
    Ann M Powers
    Division of Vector Borne Infectious Diseases, Centers for Disease Control and Prevention, 3150 Rampart Road, Fort Collins, CO 80521, USA
    J Gen Virol 88:2363-77. 2007
  4. ncbi request reprint Genetic relationships among Mayaro and Una viruses suggest distinct patterns of transmission
    Ann M Powers
    Centers for Disease Control and Prevention, Division of Vector Borne Infectious Diseases, Fort Collins, Colorado 80522, USA
    Am J Trop Med Hyg 75:461-9. 2006
  5. ncbi request reprint Chikungunya
    Ann M Powers
    Centers for Disease Control and Prevention, Fort Collins, CO 80521, USA
    Clin Lab Med 30:209-19. 2010
  6. pmc Treatment with cationic liposome-DNA complexes (CLDCs) protects mice from lethal Western equine encephalitis virus (WEEV) challenge
    Christopher H Logue
    Division of Vector Borne Infectious Diseases, Centers for Disease Control, Fort Collins, CO 80521, USA
    Antiviral Res 87:195-203. 2010
  7. pmc Molecular determinants of mouse neurovirulence and mosquito infection for Western equine encephalitis virus
    Eric C Mossel
    Arthropod Borne and Infectious Diseases Laboratory, Department of Microbiology, Immunology and Pathology, Colorado State University, Fort Collins, Colorado, United States of America
    PLoS ONE 8:e60427. 2013
  8. ncbi request reprint Liposome-antigen-nucleic acid complexes protect mice from lethal challenge with western and eastern equine encephalitis viruses
    Aaron T Phillips
    Arthropod Borne and Infectious Disease Laboratory, Department of Microbiology, Immunology, and Pathology, Colorado State University, Fort Collins, Colorado, USA
    J Virol 88:1771-80. 2014
  9. doi request reprint Prevalence of antibodies to alphaviruses and flaviviruses in free-ranging game animals and nonhuman primates in the greater Congo basin
    Rebekah C Kading
    Centers for Disease Control and Prevention, Division of Vector Borne Diseases, Arbovirus Diseases Branch, Virology Activity, 3156 Rampart Road, Fort Collins, Colorado 80521, USA
    J Wildl Dis 49:587-99. 2013
  10. doi request reprint Chikungunya virus: possible impact on transfusion medicine
    Lyle R Petersen
    Division of Vector Borne Infectious Diseases, Centers for Disease Control and Prevention, Fort Collins, CO 80521, USA
    Transfus Med Rev 24:15-21. 2010

Collaborators

Detail Information

Publications35

  1. ncbi request reprint Genomic evolution and phenotypic distinctions of Chikungunya viruses causing the Indian Ocean outbreak
    Ann M Powers
    Division of Vector Borne Infectious Diseases, Centers for Disease Control and Prevention, 3150 Rampart Road, Fort Collins, CO 80521, USA
    Exp Biol Med (Maywood) 236:909-14. 2011
    ..This review will highlight some of the most significant recent research developments obtained using these cutting edge approaches for CHIKV...
  2. pmc O'nyong nyong virus molecular determinants of unique vector specificity reside in non-structural protein 3
    Kali D Saxton-Shaw
    Division of Vector Borne Infectious Diseases, Centers for Disease Control and Prevention, Fort Collins, Colorado, United States of America
    PLoS Negl Trop Dis 7:e1931. 2013
    ..5%. No other single gene or viral region addition was able to restore infection rates. Thus, we have shown that a non-structural genome element involved in viral replication is a major element involved in ONNV's unique vector specificity...
  3. ncbi request reprint Changing patterns of chikungunya virus: re-emergence of a zoonotic arbovirus
    Ann M Powers
    Division of Vector Borne Infectious Diseases, Centers for Disease Control and Prevention, 3150 Rampart Road, Fort Collins, CO 80521, USA
    J Gen Virol 88:2363-77. 2007
  4. ncbi request reprint Genetic relationships among Mayaro and Una viruses suggest distinct patterns of transmission
    Ann M Powers
    Centers for Disease Control and Prevention, Division of Vector Borne Infectious Diseases, Fort Collins, Colorado 80522, USA
    Am J Trop Med Hyg 75:461-9. 2006
    ..These analyses provide possible explanations for the natural ecology and transmission of MAYV and UNAV...
  5. ncbi request reprint Chikungunya
    Ann M Powers
    Centers for Disease Control and Prevention, Fort Collins, CO 80521, USA
    Clin Lab Med 30:209-19. 2010
    ..A discussion of the virus, its epidemiology, diagnostic criteria, and immunity are presented in this article...
  6. pmc Treatment with cationic liposome-DNA complexes (CLDCs) protects mice from lethal Western equine encephalitis virus (WEEV) challenge
    Christopher H Logue
    Division of Vector Borne Infectious Diseases, Centers for Disease Control, Fort Collins, CO 80521, USA
    Antiviral Res 87:195-203. 2010
    ....
  7. pmc Molecular determinants of mouse neurovirulence and mosquito infection for Western equine encephalitis virus
    Eric C Mossel
    Arthropod Borne and Infectious Diseases Laboratory, Department of Microbiology, Immunology and Pathology, Colorado State University, Fort Collins, Colorado, United States of America
    PLoS ONE 8:e60427. 2013
    ....
  8. ncbi request reprint Liposome-antigen-nucleic acid complexes protect mice from lethal challenge with western and eastern equine encephalitis viruses
    Aaron T Phillips
    Arthropod Borne and Infectious Disease Laboratory, Department of Microbiology, Immunology, and Pathology, Colorado State University, Fort Collins, Colorado, USA
    J Virol 88:1771-80. 2014
    ..We discuss plausible mechanisms as well the potential utility of our LANAC formulation as a pan-alphavirus vaccine. ..
  9. doi request reprint Prevalence of antibodies to alphaviruses and flaviviruses in free-ranging game animals and nonhuman primates in the greater Congo basin
    Rebekah C Kading
    Centers for Disease Control and Prevention, Division of Vector Borne Diseases, Arbovirus Diseases Branch, Virology Activity, 3156 Rampart Road, Fort Collins, Colorado 80521, USA
    J Wildl Dis 49:587-99. 2013
    ..Overall, our results demonstrate a high prevalence of neutralizing antibodies against multiple arboviruses in wildlife in equatorial Africa...
  10. doi request reprint Chikungunya virus: possible impact on transfusion medicine
    Lyle R Petersen
    Division of Vector Borne Infectious Diseases, Centers for Disease Control and Prevention, Fort Collins, CO 80521, USA
    Transfus Med Rev 24:15-21. 2010
    ..Assays suitable for testing donations for CHIKV RNA are not yet available, and given the highly geographically and temporally sporadic nature of CHIKV outbreaks, there may be considerable reluctance to develop and implement them...
  11. ncbi request reprint Sunguru virus: a novel virus in the family Rhabdoviridae isolated from a chicken in north-western Uganda
    Jeremy P Ledermann
    Division of Vector Borne Diseases, Centers for Disease Control and Prevention, 3156 Rampart Rd, Fort Collins, CO 80521, USA
    J Gen Virol 95:1436-43. 2014
    ..4 % infection rate in the body but no dissemination of the virus to the salivary glands; this suggests that this novel virus is not arthropod borne as some other members of the family Rhabdoviridae. ..
  12. pmc Virulence variation among isolates of western equine encephalitis virus in an outbred mouse model
    Christopher H Logue
    Division of Vector Borne Infectious Diseases, Centers for Disease Control and Prevention, Fort Collins, CO 80521, USA
    J Gen Virol 90:1848-58. 2009
    ....
  13. pmc Evaluation of widely used diagnostic tests to detect West Nile virus infections in horses previously infected with St. Louis encephalitis virus or dengue virus type 2
    Jeremy P Ledermann
    Centers for Disease Control and Prevention, Division of Vector Borne Infectious Diseases, 3150 Rampart Road, Fort Collins, CO 80521, USA
    Clin Vaccine Immunol 18:580-7. 2011
    ..Of great importance, we demonstrated that timing of sample collection and the need for multiple samples are important, as the infecting etiology could be misdiagnosed if only a single sample is tested...
  14. doi request reprint Japanese encephalitis virus remains an important cause of encephalitis in Thailand
    Sonja J Olsen
    Divison of Emerging Infections and Surveillance Services, Centers for Disease Control and Prevention Collaboration, 1600 Clifton Road, MS C 12, Atlanta, GA 30333, USA
    Int J Infect Dis 14:e888-92. 2010
    ..Japanese encephalitis virus (JEV) is endemic in Thailand and prevention strategies include vaccination, vector control, and health education...
  15. pmc West Nile virus-infected mosquitoes, Louisiana, 2002
    Marvin S Godsey
    Division of Vector Borne Infectious Diseases, Centers for Disease Control and Prevention, Fort Collins, Colorado 80522, USA
    Emerg Infect Dis 11:1399-404. 2005
    ..Mosquito infection rates among sites ranged from 0.8/1,000 to 10.9/1,000. Results suggest that Cx. quinquefasciatus was the primary epizootic/epidemic vector, with other species possibly playing a secondary role...
  16. doi request reprint Chikungunya fever: an epidemiological review of a re-emerging infectious disease
    J Erin Staples
    Arboviral Diseases Branch, Division of Vector Borne Infectious Diseases, Centers for Disease Control and Prevention, Fort Collins, Colorado 80521, USA
    Clin Infect Dis 49:942-8. 2009
    ....
  17. pmc Effects of an opal termination codon preceding the nsP4 gene sequence in the O'Nyong-Nyong virus genome on Anopheles gambiae infectivity
    Kevin M Myles
    Division of Vector Borne Infectious Diseases, Centers for Disease Control and Prevention, Fort Collins, CO, USA
    J Virol 80:4992-7. 2006
    ..Taken together, these results suggest that the primary fitness advantage provided to ONNV by the presence of an opal codon between nsP3 and nsP4 is related to mosquito infectivity...
  18. pmc Bioluminescent imaging and histopathologic characterization of WEEV neuroinvasion in outbred CD-1 mice
    Aaron T Phillips
    Department of Microbiology, Immunology, and Pathology, Colorado State University, Fort Collins, Colorado, United States of America
    PLoS ONE 8:e53462. 2013
    ..BLM provides a quantifiable measure of alphaviral neural disease progression and a method for evaluating antiviral strategies...
  19. pmc Search strategy has influenced the discovery rate of human viruses
    Ronald Rosenberg
    Division of Vector Borne Diseases, Centers for Disease Control and Prevention, Fort Collins, CO 80521, USA
    Proc Natl Acad Sci U S A 110:13961-4. 2013
    ..The productivity of this strategy illustrates the importance of location, approach, long-term commitment, and sponsorship in the discovery of emerging pathogens. ..
  20. doi request reprint Zika virus outbreak on Yap Island, Federated States of Micronesia
    Mark R Duffy
    Division of Vector Borne Infectious Diseases, National Center for Zoonotic, Vector Borne, and Enteric Diseases, Centers for Disease Control and Prevention, Fort Collins, CO 80521, USA
    N Engl J Med 360:2536-43. 2009
    ..No previous outbreaks and only 14 cases of Zika virus disease have been previously documented...
  21. pmc Removal of species constraints in antibody detection
    Alison Jane Basile
    Division of Vector Borne Infectious Diseases, Centers for Disease Control and Prevention, 3150 Rampart Rd, Fort Collins, CO 80521, USA
    Clin Vaccine Immunol 17:56-61. 2010
    ..Agent-specific adaptations of this simple format should facilitate expanded surveillance and diagnostic capabilities regarding pathogens of human and veterinary importance...
  22. pmc Glycosaminoglycan binding properties of natural venezuelan equine encephalitis virus isolates
    Eryu Wang
    Center for Tropical Diseases and Department of Pathology, University of Texas Medical Branch, Galveston 77555 0609, USA
    J Virol 77:1204-10. 2003
    ....
  23. ncbi request reprint Differential infectivities of o'nyong-nyong and chikungunya virus isolates in Anopheles gambiae and Aedes aegypti mosquitoes
    Dana L Vanlandingham
    Department of Pathology, University of Texas Medical Branch, Galveston, Texas 77555 0609, USA
    Am J Trop Med Hyg 72:616-21. 2005
    ..gambiae and Ae. aegypti. The species specificity in vivo was reflected by in vitro experiments using culicine and anopheline-derived cell lines...
  24. pmc A single positively selected West Nile viral mutation confers increased virogenesis in American crows
    Aaron C Brault
    Center for Vector Borne Diseases and Department of Pathology, Microbiology and Immunology, School of Veterinary Medicine, University of California, Davis, California 95616, USA
    Nat Genet 39:1162-6. 2007
    ..These phenotypic and evolutionary results provide compelling evidence for the positive selection of a mutation encoding increased viremia potential and virulence in the AMCR sentinel bird species...
  25. ncbi request reprint Entomologic investigations of a chikungunya virus epidemic in the Union of the Comoros, 2005
    Rosemary C Sang
    Kenya Medical Research Institute, Nairobi, Kenya
    Am J Trop Med Hyg 78:77-82. 2008
    ..This was supported by high container (31.1%), household (68%), and Breteau (126) indices, with discarded tires (58.8%) and small cooking and water storage vessels (31.1%) registering the highest container indices...
  26. ncbi request reprint Drought-associated chikungunya emergence along coastal East Africa
    Jean Paul Chretien
    Department of Defense Global Emerging Infections Surveillance and Response System DoD GEIS, Walter Reed Army Institute of Research, Silver Spring, Maryland 20910 7500, USA
    Am J Trop Med Hyg 76:405-7. 2007
    ..These results suggest that drought-affected populations may be at heightened risk for chikungunya fever, and underscore the need for safe water storage during drought relief operations...
  27. pmc Arbovirus evolution in vivo is constrained by host alternation
    Lark L Coffey
    Department of Pathology and Center for Tropical Diseases, University of Texas Medical Branch, Galveston, TX 77555, USA
    Proc Natl Acad Sci U S A 105:6970-5. 2008
    ..These results suggest that arbovirus adaptation and evolution is limited by obligate host alternation and predict that arboviral emergence via host range changes may be less frequent than that of single host animal RNA viruses...
  28. ncbi request reprint Seroprevalence of Chikungunya virus infection on Grande Comore Island, union of the Comoros, 2005
    Kibet Sergon
    Epidemiology and Laboratory Training Program, Nairobi, Kenya Ministry of Health, Moroni, Comoros
    Am J Trop Med Hyg 76:1189-93. 2007
    ..The findings suggest that CHIKV was broadly transmitted during the outbreak with a high attack rate. Although not fatal during this outbreak, CHIKV infection caused significant morbidity and decreased economic productivity...
  29. ncbi request reprint Recombinant alphaviruses are safe and useful serological diagnostic tools
    Haolin Ni
    Center for Biodefense and Emerging Infectious Diseases, Department of Pathology, University of Texas Medical Branch, Galveston, Texas 77555, USA
    Am J Trop Med Hyg 76:774-81. 2007
    ..Chimeric viruses were produced efficiently in cell culture and were as effective as the parental virus for identifying infection of humans, horses, and rodents in these serological assays...
  30. pmc West Nile virus in horses, Guatemala
    Maria Eugenia Morales-Betoulle
    Emerg Infect Dis 12:1038-9. 2006
  31. ncbi request reprint Short report: serological evidence of West Nile virus activity in El Salvador
    Lilian Cruz
    Field Epidemiology Training Program, Ministry of Public Health and Social Welfare, San Salvador, El Salvador
    Am J Trop Med Hyg 72:612-5. 2005
    ..Ten of these infections were confirmed by plaque reduction neutralization tests, suggesting West Nile virus has extended its range and spread to Central America...
  32. pmc Venezuelan equine encephalitis emergence: enhanced vector infection from a single amino acid substitution in the envelope glycoprotein
    Aaron C Brault
    Center for Biodefense and Emerging Infectious Diseases and Department of Pathology, University of Texas Medical Branch, Galveston, TX 77555 0609, USA
    Proc Natl Acad Sci U S A 101:11344-9. 2004
    ..Our findings underscore the capacity of RNA viruses to alter their vector host range through minor genetic changes, resulting in the potential for disease emergence...
  33. ncbi request reprint Serologic survey of domestic animals for zoonotic arbovirus infections in the Lacandón Forest region of Chiapas, Mexico
    Armando Ulloa
    Centro de Investigacion de Paludismo, Tapachula, Chiapas, Mexico
    Vector Borne Zoonotic Dis 3:3-9. 2003
    ..There was no evidence for transmission of the other viruses (ROC, ILH, EEE, WEE) in the study area...
  34. pmc Vector infection determinants of Venezuelan equine encephalitis virus reside within the E2 envelope glycoprotein
    Aaron C Brault
    Center for Tropical Diseases and Department of Pathology, University of Texas Medical Branch, Galveston, Texas 77555 0609, USA
    J Virol 76:6387-92. 2002
    ....
  35. pmc Positively charged amino acid substitutions in the e2 envelope glycoprotein are associated with the emergence of venezuelan equine encephalitis virus
    Aaron C Brault
    Center for Tropical Diseases and Department of Pathology, University of Texas Medical Branch, Galveston, Texas 77555 0609, USA
    J Virol 76:1718-30. 2002
    ..Maximum-likelihood analysis indicated that one change at E2 position 213 has been influenced by positive selection and convergent evolution of the epizootic phenotype...