Christine M Pfeiffer


Affiliation: Centers for Disease Control and Prevention
Country: USA


  1. Pfeiffer C, Zhang M, Lacher D, Molloy A, Tamura T, Yetley E, et al. Comparison of serum and red blood cell folate microbiologic assays for national population surveys. J Nutr. 2011;141:1402-9 pubmed publisher
    ..These findings indicate how assay variations influence MA folate results and how those variations can affect population data. To ensure data comparability, better assay harmonization is needed. ..
  2. Pfeiffer C, Hughes J, Lacher D, Bailey R, Berry R, Zhang M, et al. Estimation of trends in serum and RBC folate in the U.S. population from pre- to postfortification using assay-adjusted data from the NHANES 1988-2010. J Nutr. 2012;142:886-93 pubmed publisher
    ..The MBA-equivalent pre- and postfortification reference concentrations will inform countries that plan folic acid fortification or that need to evaluate its impact. ..
  3. request reprint
    Pfeiffer C, Cook J, Mei Z, Cogswell M, Looker A, Lacher D. Evaluation of an automated soluble transferrin receptor (sTfR) assay on the Roche Hitachi analyzer and its comparison to two ELISA assays. Clin Chim Acta. 2007;382:112-6 pubmed
    ..sTfR data measured with an immunoturbidimetric assay can be compared to a commonly used ELISA assay, and can be used in the body iron model through regression equations obtained in the present study. ..
  4. Whitehead R, Zhang M, Sternberg M, Schleicher R, Drammeh B, Mapango C, et al. Effects of preanalytical factors on hemoglobin measurement: A comparison of two HemoCue® point-of-care analyzers. Clin Biochem. 2017;50:513-520 pubmed publisher
    ..While the Hb-301 performed better in high humidity conditions, the Hb-201+ provided more user flexibility regarding delayed Hb reading. ..
  5. Pfeiffer C, Sternberg M, Schleicher R, Haynes B, Rybak M, Pirkle J. The CDC's Second National Report on Biochemical Indicators of Diet and Nutrition in the U.S. Population is a valuable tool for researchers and policy makers. J Nutr. 2013;143:938S-47S pubmed publisher
    ..Tabulation and graphical presentation of NHANES data in the Second Nutrition Report benefits those organizations involved in developing and evaluating nutrition policy. ..
  6. Fazili Z, Sternberg M, Paladugula N, Whitehead R, Chen H, Pfeiffer C. The loss of 5-methyltetrahydrofolate in human serum under suboptimal preanalytical conditions can only partially be recovered by an oxidation product. J Nutr. 2014;144:1873-9 pubmed publisher
    ..Folic acid generally showed good stability. To avoid folate losses, unprocessed whole blood should be protected from elevated temperatures and serum should not be refrigerated for >2 d or for a long term stored at -20°C. ..
  7. Pfeiffer C, Sternberg M, Fazili Z, Yetley E, Lacher D, Bailey R, et al. Unmetabolized folic acid is detected in nearly all serum samples from US children, adolescents, and adults. J Nutr. 2015;145:520-31 pubmed publisher
    ..These new UMFA data in US persons ≥1 y of age provide much-needed information on this vitamer in a fortified population with relatively high use of dietary supplements. ..
  8. Pfeiffer C, Sternberg M, Caldwell K, Pan Y. Race-ethnicity is related to biomarkers of iron and iodine status after adjusting for sociodemographic and lifestyle variables in NHANES 2003-2006. J Nutr. 2013;143:977S-85S pubmed publisher
  9. Schleicher R, Sternberg M, Looker A, Yetley E, Lacher D, Sempos C, et al. National Estimates of Serum Total 25-Hydroxyvitamin D and Metabolite Concentrations Measured by Liquid Chromatography-Tandem Mass Spectrometry in the US Population during 2007-2010. J Nutr. 2016;146:1051-61 pubmed publisher
    ..The strong correlation between C3-epi-25(OH)D3 and 25(OH)D3 may be because the epimer is a metabolite of 25(OH)D3. The presence of 25(OH)D2 mainly in older persons is likely a result of high-dose prescription vitamin D2. ..

More Information


  1. Pfeiffer C, Looker A. Laboratory methodologies for indicators of iron status: strengths, limitations, and analytical challenges. Am J Clin Nutr. 2017;106:1606S-1614S pubmed publisher
    ..Additional consideration of methodologies, interpretation of indicators, and analytic standardization is important for further improvements in iron status assessment. ..
  2. Pfeiffer C, Sternberg M, Schleicher R, Rybak M. Dietary supplement use and smoking are important correlates of biomarkers of water-soluble vitamin status after adjusting for sociodemographic and lifestyle variables in a representative sample of U.S. adults. J Nutr. 2013;143:957S-65S pubmed publisher
    ..Supplement use and smoking were important correlates of biomarkers of WSV status. ..