Research Topics
| A J ParkinsonSummaryAffiliation: Centers for Disease Control and Prevention Country: USA Publications
| Collaborators
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Detail Information
Publications
International Circumpolar Surveillance, an Arctic network for the surveillance of infectious diseasesAlan J Parkinson
Arctic Investigations Program, National Center for Preparedness, Detection, and Control of Infectious Diseases, Centers for Disease Control and Prevention, Anchorage, AK 99508, USA
Emerg Infect Dis 14:18-24. 2008....- The International Polar Year, 2007-2008, an opportunity to focus on infectious diseases in Arctic regionsAlan J Parkinson
Arctic Investigations Program, National Center for Preparedness, Detection, and Control of Infectious Diseases, Centers for Disease Control and Prevention, Anchorage, AK 99508, USA
Emerg Infect Dis 14:1-3. 2008..Notable achievements included launching the first satellite, measurement of atmospheric greenhouse gases, delineating the system of mid-ocean ridges, and confirming the theory of plate tectonics... 
The International Polar year 2007-2008; the Arctic human health legacyAlan J Parkinson
Arctic Investigations Program, Centers for Disease Control and Prevention, Anchorage, Alaska 995098, USA
Alaska Med 49:11-3. 2007....- Improving human health in the Arctic: the expanding role of the Arctic Council's Sustainable Development Working GroupAlan J Parkinson
Arctic Investigations Program, Centers for Disease Control and Prevention, Anchorage, AK 99508, USA
Int J Circumpolar Health 69:304-13. 2010.... - High prevalence of Helicobacter pylori in the Alaska native population and association with low serum ferritin levels in young adultsA J Parkinson
Arctic Investigations Program, National Center for Infectious Diseases, Centers for Disease Control and Prevention, Public Health Service, U S Department of Health and Human Services, Anchorage, Alaska 99508, USA
Clin Diagn Lab Immunol 7:885-8. 2000..pylori-specific IgG was found, particularly for people aged less than 20 years. H. pylori may be a factor contributing to the iron deficiency anemia in the Alaska Native population... - Bacterial pathogens in chronic otitis media with effusion in Alaska Native childrenA J Parkinson
Arctic Investigations Program, U S Department of Health and Human Services, Anchorage, Alaska 99508, USA
Alaska Med 41:27-33. 1999..However, 88% of infants in the study had their first acute otitis media episode before 1 year of age... - Serotype distribution and antimicrobial resistance patterns of invasive isolates of Streptococcus pneumoniae: Alaska, 1991-1998K M Rudolph
Arctic Investigations Program, National Center for Infectious Diseases, Centers for Disease Control and Prevention, Public Health Service, US Department of Health and Human Services, Anchorage, AK 99508, USA
J Infect Dis 182:490-6. 2000..Twelve percent of invasive isolates were resistant to >/=2 classes of antibiotics; of these, serotype 6B accounted for 33%, and 63% were recovered from children <5 years old... - Characterization of a multidrug-resistant clone of invasive Streptococcus pneumoniae serotype 6B in Alaska by using pulsed-field gel electrophoresis and PspA serotypingK M Rudolph
Molecular Diagnostics Lab, Arctic Investigations Program, Anchorage, AK 990508, USA
J Infect Dis 180:1577-83. 1999.... - A randomized trial of triple therapy for pediatric Helicobacter pylori infection and risk factors for treatment failure in a population with a high prevalence of infectionBradford D Gessner
Alaska Division of Public Health, National Center for Infectious Diseases, US Centers for Disease Control and Prevention, Anchorage, AK 99524, USA
Clin Infect Dis 41:1261-8. 2005..Few trials of treatment for Helicobacter pylori infection have been conducted in high-prevalence or pediatric populations, and risk factors for treatment failure are poorly understood... - Asymptomatic Helicobacter pylori infection and iron deficiency are not associated with decreased growth among Alaska Native children aged 7-11 yearsMarc-Andre R Chimonas
US Centers for Disease Control and Prevention, Office of Workforce and Career Development, Epidemic Intelligence Service Officer, Alaska Division of Public Health, Anchorage, Alaska 99524, USA
Helicobacter 11:159-67. 2006..CONCLUSIONS: H. pylori infection is not related to growth among Alaska Native children aged 7-11 years. Growth deficiency should not be considered an indication for H. pylori therapy... - A controlled, household-randomized, open-label trial of the effect that treatment of Helicobacter pylori infection has on iron deficiency in children in rural AlaskaBradford D Gessner
Section of Epidemiology, Alaska Division of Public Health, National Center for Infectious Diseases, US Centers for Disease Control and Prevention, Anchorage, 99524, USA
J Infect Dis 193:537-46. 2006..Previous small or uncontrolled studies have reported that successful treatment of H. pylori infection may resolve iron deficiency or anemia... - The international polar year 2007-2008; the Arctic human health legacyAlan J Parkinson
Arctic Investigations Program, Centers for Disease Control and Prevention, USA
Alaska Med 49:43-5. 2007.... 
Controlled, household-randomized, open-label trial of the effect of treatment of Helicobacter pylori infection on iron deficiency among children in rural Alaska: results at 40 monthsRyan P Fagan
Epidemic Intelligence Service, Centers for Disease Control and Prevention, Atlanta, Georgia and Alaska Division of Public Health, Anchorage, Alaska
J Infect Dis 199:652-60. 2009..We hypothesized that 14 months was to early to resolve H. pylori-induced gastric damage. Consequently, we conducted a 40-month follow-up...- Persistence of antibody to hepatitis B and protection from disease among Alaska natives immunized at birthCatherine M Dentinger
Arctic Investigations Program, National Center for Infectious Diseases, Centers for Disease Control and Prevention, Anchorage, AK, USA
Pediatr Infect Dis J 24:786-92. 2005..Transient anti-HBc appeared in a small percentage of children; however, none developed clinical signs of hepatitis or chronic HBV infection... - Reemergence, in southwestern Alaska, of invasive Haemophilus influenzae type b disease due to strains indistinguishable from those isolated from vaccinated childrenLynne A Lucher
Arctic Investigations Program, National Center for Infectious Diseases, Centers for Disease Control and Prevention, Anchorage, Alaska 99508, USA
J Infect Dis 186:958-65. 2002..Continued monitoring of Hib carriage may provide insights into the epidemiology of continued transmission in an era of widespread vaccination... - Emerging infectious diseases in Alaska and the Arctic: a review and a strategy for the 21st centuryJ C Butler
Arctic Investigations Program, National Center for Infectious Diseases, Centers for Disease Control and Prevention, Anchorage, AK, USA
Alaska Med 41:35-43. 1999.... - Dynamics of Helicobacter pylori-specific immunoglobulin G for 2 years after successful eradication of Helicobacter pylori infection in an American Indian and Alaska Native populationKaren M Miernyk
Alaska Native Tribal Health Consortium, Arctic Investigations Program, Centers for Disease Control and Prevention, 4055 Tudor Centre Dr, Anchorage, AK 99508, USA
Clin Vaccine Immunol 14:85-6. 2007..Two months after treatment, 82% of H. pylori-negative persons remained seropositive. While there were declines in H. pylori antibodies for 12 months, after 24 months 71% of persons remained seropositive... - Alaska sentinel surveillance for antimicrobial resistance in Helicobacter pylori isolates from Alaska native persons, 1999-2003Michael G Bruce
Arctic Investigations Program, National Center for Infectious Diseases, Centers for Disease Control and Prevention, Anchorage, AK 99508, USA
Helicobacter 11:581-8. 2006..Previous studies in Alaska have demonstrated elevated proportions of antimicrobial resistance among Helicobacter pylori isolates... - Invasive pneumococcal disease epidemiology and effectiveness of 23-valent pneumococcal polysaccharide vaccine in Alaska native adultsRosalyn J Singleton
Arctic Investigations Program, National Center for Infectious Diseases, Centers for Disease Control and Prevention, Anchorage, AK 99508, USA
Vaccine 25:2288-95. 2007..PPV-23 vaccine effectiveness was confirmed in younger Alaska Native adults but not among adults > or =55 years... - International Circumpolar Surveillance System for invasive pneumococcal disease, 1999-2005Michael G Bruce
Arctic Investigations Program, National Center for Preparedness, Detection, and Control of Infectious Diseases, Centers for Disease Control and Prevention, 4055 Tudor Circle Drive, Anchorage, AK 99508, USA
Emerg Infect Dis 14:25-33. 2008..IPD rates are high among indigenous persons and children in Arctic countries. After vaccine introduction, IPD caused by non-PCV7 serotypes increased in Alaska... - Epidemiology of Haemophilus influenzae serotype a, North American Arctic, 2000-2005Michael G Bruce
Arctic Investigations Program, National Center for Preparedness, Detection, and Control of Infectious Diseases, Centers for Disease Control and Prevention, 4055 Tudor Circle Drive, Anchorage, AK 99508, USA
Emerg Infect Dis 14:48-55. 2008..Serotype a is now the most common H. influenzae serotype in the North American Arctic; the highest rates are among indigenous children... - Potential impacts of climate change on infectious diseases in the ArcticAlan J Parkinson
Arctic Investigations Program, Centers for Disease Control and Prevention, Anchorage Alaska 99508, USA
Int J Circumpolar Health 64:478-86. 2005.... - Climate change: the importance of placeJeremy J Hess
National Center for Environmental Health, CDC, Atlanta, Georgia 30341 3717, USA
Am J Prev Med 35:468-78. 2008..In considering the importance of place, we highlight the concepts of community resilience and risk management, key aspects of a robust response to climate change in public health and other sectors... - Immunogenicity and reactogenicity of pneumococcal polysaccharide and conjugate vaccines in alaska native adults 55-70 years of ageKaren M Miernyk
Division of Emerging Infections and Surveillance Systems, Alaska Native Tribal Health Consortium, National Center for Preparedness, Detection, and Control of Infectious Diseases, Anchorage, Alaska 99508, USA
Clin Infect Dis 49:241-8. 2009.... - Immunogenicity and reactogenicity to Haemophilus influenzae type B (Hib) conjugate vaccine among rural Alaska adultsCatherine M Dentinger
Arctic Investigations Program, National Center for Infectious Diseases, Centers for Disease Control and Prevention, Anchorage, Alaska, USA
Hum Vaccin 2:24-8. 2006..As part of a project to eliminate Hib carriage in three rural villages, we evaluated a cohort of Alaska adults for antibody response and reactogenicity to a single dose of Hib conjugate vaccine (HbOC)... - Immunologic response to Haemophilus influenzae type b (Hib) conjugate vaccine and risk factors for carriage among Hib carriers and noncarriers in Southwestern AlaskaHenry C Baggett
CDC, Division of Global Migration and Quarantine, MS E03, 1600 Clifton Rd, Atlanta, GA 30333, USA
Clin Vaccine Immunol 13:620-6. 2006.... - The relationship among previous antimicrobial use, antimicrobial resistance, and treatment outcomes for Helicobacter pylori infectionsBrian J McMahon
Arctic Investigations Program, National Center for Infectious Diseases, Centers for Disease Control and Prevention, and Alaska Native Medical Center, Anchorage, Alaska 99508, USA
Ann Intern Med 139:463-9. 2003..The relationship between previous antimicrobial treatments and infection with drug-resistant Helicobacter pylori is unknown... - Antibody levels and protection after hepatitis B vaccination: results of a 15-year follow-upBrian J McMahon
Arctic Investigations Program, National Center for Infectious Diseases, Centers for Disease Control and Prevention, and the Alaska Native Medical Center, Anchorage, Alaska 99508, USA
Ann Intern Med 142:333-41. 2005..The duration of protection afforded by hepatitis B vaccination is unknown... - Evaluation of seaFAST, a rapid fluorescent in situ hybridization test, for detection of Helicobacter pylori and resistance to clarithromycin in paraffin-embedded biopsy sectionsJulie M Morris
Arctic Investigations Program, CDC, 4055 Tudor Centre Drive, Anchorage, AK 99508, USA
J Clin Microbiol 43:3494-6. 2005..The FISH method was found to be 97% sensitive, 94% specific for the detection of H. pylori and comparable to agar dilution for the detection of resistance to clarithromycin... - Impact of heptavalent pneumococcal conjugate vaccine on invasive disease, antimicrobial resistance and colonization in Alaska Natives: progress towards elimination of a health disparityThomas W Hennessy
Arctic Investigations Program, National Center for Infectious Diseases, Centers for Disease Control and Prevention, Anchorage, AK 99508, USA
Vaccine 23:5464-73. 2005..001 each). PCV7 vaccine has eliminated a longstanding disparity of vaccine-type IPD for AN children. Decreased vaccine-type colonization and IPD in adults demonstrate indirect vaccine effects... - Changes in antibiotic-prescribing practices and carriage of penicillin-resistant Streptococcus pneumoniae: A controlled intervention trial in rural AlaskaThomas W Hennessy
Arctic Investigations Program, National Center for Infectious Diseases, Centers for Disease Control and Prevention, Anchorage, AK, 99508, USA
Clin Infect Dis 34:1543-50. 2002..This suggests that reducing the carriage of serotypes associated with antibiotic resistance by use of pneumococcal conjugate vaccines may have a greater short-term impact than does decreasing antibiotic use... - Endemic iron deficiency associated with Helicobacter pylori infection among school-aged children in AlaskaHenry C Baggett
Alaska Division of Public Health, Anchorage, Alaska
Pediatrics 117:e396-404. 2006..The objective of this study was to estimate the prevalence of iron deficiency, iron-deficiency anemia, and active H pylori infection among school-aged children in rural Alaska... - Reinfection after successful eradication of Helicobacter pylori: a 2-year prospective study in Alaska NativesB J McMahon
Department of Internal Medicine, Alaska Native Medical Center, Anchorage, USA
Aliment Pharmacol Ther 23:1215-23. 2006..Limited information exists regarding risk factors for reinfection after cure of Helicobacter pylori infection... - The relationship between previous fluoroquinolone use and levofloxacin resistance in Helicobacter pylori infectionJohn J Carothers
Native Medical Center, Anchorage, Alaska, USA
Clin Infect Dis 44:e5-8. 2007..pylori isolates that were resistant to levofloxacin. Levofloxacin resistance was associated with any prior fluoroquinolone use over the previous 10 years and with the total number of fluoroquinolone courses prescribed (P<.001)... - Invasive pneumococcal disease among Navajo adults, 1989-1998James P Watt
Respiratory Diseases Branch, Division of Bacterial and Mycotic Diseases, Centers for Disease Control and Prevention, Atlanta, Georgia, USA
Clin Infect Dis 38:496-501. 2004..Navajo adults have rates of IPD that are 3-5-fold higher than those of the general US population. Additional research is needed to understand the reasons for this elevated risk and to develop prevention strategies... - Duration of hepatitis B immunity in low risk children receiving hepatitis B vaccinations from birthKenneth M Petersen
Arctic Investigations Program, National Center for Infectious Diseases, Centers for Disease Control and Prevention, Alaska Native Tribal Health Consortium, Anchorage, AK 99508, USA
Pediatr Infect Dis J 23:650-5. 2004..Additional long term studies of low risk infants are needed to determine duration of protection and the necessity for or timing of booster doses... - Immunogenicity of a heptavalent pneumococcal conjugate vaccine in Apache and Navajo Indian, Alaska native, and non-native American children aged <2 yearsK M Miernyk
Arctic Investigations Program, National Center for Infectious Diseases, Centers for Disease Control and Prevention, US Public Health Service, US Department of Health and Human Services, Anchorage, AK, 99508, USA
Clin Infect Dis 31:34-41. 2000.... - Evaluation of the response to a booster dose of hepatitis B vaccine in previously immunized healthcare workersJ L Williams
Alaska Native Medical Center, Viral Hepatitis Program, ANC HEP, 4315 Diplomacy Drive, Anchorage, AK 99508, USA
Vaccine 19:4081-5. 2001..However, the absolute duration of protection from immunization is unknown. The purpose of this randomized comparison trial was to determine how previously immunized HCW respond to different booster doses of hepatitis B vaccine... - Epidemiology of invasive Streptococcus pneumoniae among Navajo children in the era before use of conjugate pneumococcal vaccines, 1989-1996Katherine L O'Brien
Center for American Indian Health, Johns Hopkins Bloomberg School of Public Health, Baltimore, MD 21205, USA
Am J Epidemiol 160:270-8. 2004..These data are critical for assessing the impact of these vaccines in this high-risk population... - Changing epidemiology of invasive pneumococcal disease among White Mountain Apache persons in the era of the pneumococcal conjugate vaccineRochelle Lacapa
Center for American Indian Health, Bloomberg School of Public Health, Johns Hopkins University, Baltimore, Maryland, USA
Clin Infect Dis 47:476-84. 2008..We aimed to assess the impact of PCV7 and 23-valent pneumococcal polysaccharide vaccine on the rate of IPD among White Mountain Apache persons... - Effect of high-dose amoxicillin on the prevalence of penicillin-resistant Streptococcus pneumoniae in rural AlaskaThomas W Hennessy
JAMA 287:2078-9. 2002 - Impact of conjugate vaccine on transmission of antimicrobial-resistant Streptococcus pneumoniae among Alaskan childrenSarah Y Park
From the Office of Workforce and Career Development, Centers for Disease Control and Prevention CDC, Atlanta, GA, USA
Pediatr Infect Dis J 27:335-40. 2008..The impact of heptavalent pneumococcal conjugate vaccine (PCV7) on transmission of antimicrobial-resistant Streptococcus pneumoniae is an important concern for countries considering PCV7 introduction... - Transposable element ISHp608 of Helicobacter pylori: nonrandom geographic distribution, functional organization, and insertion specificityDangeruta Kersulyte
Department of Molecular Microbiology, Washington University School of Medicine, St. Louis, Missouri 63110, USA
J Bacteriol 184:992-1002. 2002..ISHp608 represents a widespread family of novel chimeric mobile DNA elements whose further analysis should provide new insights into transposition mechanisms and into microbial population genetic structure and genome evolution...