Research Topics
| Christopher D PaddockSummaryAffiliation: Centers for Disease Control and Prevention Country: USA Publications
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Detail Information
Publications
Rickettsia parkeri rickettsiosis and its clinical distinction from Rocky Mountain spotted feverChristopher D Paddock
Infectious Diseases Pathology Branch, Mailstop G 32, Centers for Disease Control and Prevention, 1600 Clifton Rd, Atlanta, GA 30333, USA
Clin Infect Dis 47:1188-96. 2008..parkeri and comment on distinctions between R. parkeri rickettsiosis and other United States rickettsioses...
Rocky Mountain spotted fever in ArgentinaChristopher D Paddock
Infectious Disease Pathology Branch, Division of Viral and Rickettsial Diseases, Centers for Disease Control and Prevention, Atlanta, Georgia 30333, USA
Am J Trop Med Hyg 78:687-92. 2008..These findings show the existence of RMSF in Argentina and emphasize the need for clinicians throughout the Americas to consider RMSF in patients with febrile rash illnesses...
The science and fiction of emerging rickettsiosesChristopher D Paddock
Infectious Disease Pathology Branch, Division of Viral and Rickettsial Diseases, Centers for Disease Control and Prevention, Atlanta, Georgia 30333, USA
Ann N Y Acad Sci 1166:133-43. 2009..Close inspection of mild or atypical forms of historically recognized rickettsioses and a greater emphasis on culture- and molecular-based diagnostic techniques are the keys to identifying future rickettsial agents of disease...
Rickettsia parkeri: a newly recognized cause of spotted fever rickettsiosis in the United StatesChristopher D Paddock
Division of Viral and Rickettsial Diseases, Infectious Disease Pathology Activity, Centers for Disease Control and Prevention, Atlanta, Georgia 30333, USA
Clin Infect Dis 38:805-11. 2004..parkeri rickettsiosis and possibly other novel SFG rickettsioses in the United States...
Isolation of Rickettsia akari from eschars of patients with rickettsialpoxChristopher D Paddock
Viral and Rickettsial Zoonoses Branch and Infectious Disease Pathology Activity, Division of Viral and Rickettsial Diseases, Centers for Disease Control and Prevention, Atlanta, GA 30333, USA
Am J Trop Med Hyg 75:732-8. 2006..This work emphasizes the importance and utility of culture-and molecular-based methods for the diagnosis of rickettsialpox and other eschar-associated illnesses...
Pathology and pathogenesis of fatal Bordetella pertussis infection in infantsChristopher D Paddock
Infectious Disease Pathology Branch, Centers for Disease Control and Prevention, Atlanta, Georgia 30333, USA
Clin Infect Dis 47:328-38. 2008....
Fatal hemorrhagic fever caused by West Nile virus in the United StatesChristopher D Paddock
Infectious Disease Pathology Activity, Division of Viral and Rickettsial Diseases, National Center for Infectious Diseases, Centers for Disease Control and Prevention, Atlanta, GA 30333, USA
Clin Infect Dis 42:1527-35. 2006..We describe a case of fulminant WNV infection in a 59-year-old Florida man who died following a brief illness that resembled hemorrhagic disease caused by Rickettsia reckettsii, dengue virus or yellow fever virus...
Detection of West Nile virus in formalin-fixed, paraffin-embedded human tissues by RT-PCR: a useful adjunct to conventional tissue-based diagnostic methodsJulu Bhatnagar
Infectious Disease Pathology Activity, Centers for Disease Control and Prevention, 1600 Clifton Road, N E, Mailstop G32, Atlanta, GA 30333, United States
J Clin Virol 38:106-11. 2007....
Molecular detection and typing of dengue viruses from archived tissues of fatal cases by rt-PCR and sequencing: diagnostic and epidemiologic implicationsJulu Bhatnagar
Infectious Diseases Pathology Branch, National Center for Emerging and Zoonotic Infectious Diseases, Centers for Disease Control and Prevention, Atlanta, Georgia 30333, USA
Am J Trop Med Hyg 86:335-40. 2012..The IHC detected DENV antigens in 50 (40%) cases. The RT-PCR using FFPE tissue improves detection of DENV in fatal cases and provides sequence information useful for typing and epidemiologic studies...
Myocardial injury and bacterial pneumonia contribute to the pathogenesis of fatal influenza B virus infectionChristopher D Paddock
Infectious Diseases Pathology Branch, Centers for Disease Control and Prevention, Atlanta, GA, USA
J Infect Dis 205:895-905. 2012....
Rickettsialpox in New York City: a persistent urban zoonosisChristopher D Paddock
Viral and Rickettsial Zoonoses Branch, National Center for Infectious Diseases, Centers for Disease Control and Prevention, Atlanta, Georgia 30333, USA
Ann N Y Acad Sci 990:36-44. 2003....
Molecular diagnosis of Bordetella pertussis infection by evaluation of formalin-fixed tissue specimensKathleen M Tatti
Centers for Disease Control and Prevention, National Center for Infectious Diseases, Division of Viral and Rickettsial Disease, Infectious Disease Pathology Activity, 1600 Clifton Rd, NE, Mailstop G30, Atlanta, Georgia 30333, USA
J Clin Microbiol 44:1074-6. 2006..B. pertussis was confirmed in all cases. PCR can be an invaluable retrospective diagnostic tool for evaluating archival tissues from patients with suspected fatal pertussis...
Seasonal pulses of Marburg virus circulation in juvenile Rousettus aegyptiacus bats coincide with periods of increased risk of human infectionBrian R Amman
Viral Special Pathogens Branch, Centers for Disease Control and Prevention, Atlanta, Georgia, United States of America
PLoS Pathog 8:e1002877. 2012..aegyptiacus bats existing as a large meta-population with associated virus circulation over broad geographic ranges. These findings provide a basis for developing Marburg hemorrhagic fever risk reduction strategies...
Diagnosis of invasive group a streptococcal infections by using immunohistochemical and molecular assaysJeannette Guarner
Infectious Disease Pathology Activity, National Centers for Infectious Diseases, Centers for Disease Control and Prevention, Atlanta, GA 30333, USA
Am J Clin Pathol 126:148-55. 2006..Eighteen patients had systemic infection. Immunohistochemical analysis and PCR can be used for diagnosis of GAS infections in formalin-fixed, paraffin-embedded samples...
Rocky Mountain spotted fever from an unexpected tick vector in ArizonaLinda J Demma
National Center for Infectious Diseases, Division of Viral and Rickettsial Diseases, The Centers for Disease Control and Prevention, Atlanta, GA 30333, USA
N Engl J Med 353:587-94. 2005..This disease is rarely reported in Arizona, and the principal vectors, Dermacentor species ticks, are uncommon in the state. From 2002 through 2004, a focus of Rocky Mountain spotted fever was investigated in rural eastern Arizona...
Diagnosis and management of tickborne rickettsial diseases: Rocky Mountain spotted fever, ehrlichioses, and anaplasmosis--United States: a practical guide for physicians and other health-care and public health professionalsAlice S Chapman
National Center for Infectious Diseases, CDC, Atlanta, GA 30333, USA
MMWR Recomm Rep 55:1-27. 2006....
Localization of pandemic 2009 H1N1 influenza A virus RNA in lung and lymph nodes of fatal influenza cases by in situ hybridization: new insights on virus replication and pathogenesisJulu Bhatnagar
Infectious Diseases Pathology Branch, Division of High Consequence Pathogens and Pathology, National Center for Emerging and Zoonotic Infectious Diseases, Centers for Disease Control and Prevention, Atlanta, GA 30333, USA
J Clin Virol 56:232-7. 2013..Although pH1N1 viral antigens have been demonstrated in various human tissues by immunohistochemistry (IHC), cellular localization of pH1N1 RNA in these tissues has largely remained uninvestigated...
Isolation and characterization of Bartonella bacilliformis from an expatriate EcuadorianShari L Lydy
Rickettsial Zoonoses Branch, Mail Stop G 13, Centers for Disease Control and Prevention, 1600 Clifton Road NE, Atlanta, GA 30333, USA
J Clin Microbiol 46:627-37. 2008..bacilliformis was not thought to be endemic. This study suggests that the range of B. bacilliformis may be expanding from areas of endemicity in Ecuador and that infection may present as atypical clinical disease...
Usefulness of immunohistochemical diagnosis of streptococcus pneumoniae in formalin-fixed, paraffin-embedded specimens compared with culture and gram stain techniquesJeannette Guarner
Infectious Diseases Pathology Activity, Centers for Disease Control and Prevention, Atlanta, GA 30333, USA
Am J Clin Pathol 127:612-8. 2007..Compared with culture, the immunohistochemical assay showed 100% sensitivity and 71% specificity. Immunohistochemical analysis has the diagnostic advantage of correlating host inflammatory reaction with presence of pneumococci...
Novel deer-associated parapoxvirus infection in deer huntersAmira A Roess
Epidemic Intelligence Service, Epidemiology Program Office, and the Division of High Consequence Pathogens and Pathology, National Center for Emerging and Zoonotic Infectious Diseases, Centers for Disease Control and Prevention, Atlanta, GA, USA
N Engl J Med 363:2621-7. 2010..Deer populations continue to increase, leading to the possibility that there will be more deer-associated parapoxvirus infections...
Immunohistochemical, in situ hybridization, and ultrastructural localization of SARS-associated coronavirus in lung of a fatal case of severe acute respiratory syndrome in TaiwanWun-Ju Shieh
Infectious Disease Pathology Activity, Division of Viral and Rickettsial Diseases, Center for Disease Control and Prevention, Atlanta, GA 30333, USA
Hum Pathol 36:303-9. 2005..These techniques represent valuable laboratory diagnostic modalities and provide insights into the pathogenesis of this emerging infection...
Ultrastructural characterization of pandemic (H1N1) 2009 virusCynthia S Goldsmith
Centers for Disease Control and Prevention, Atlanta, Georgia 30333, USA
Emerg Infect Dis 17:2056-9. 2011..Many morphologic characteristics were similar to those previously described for influenza virus. One of the distinctive features was dense tubular structures in the nuclei of infected cells...
Isolation of genetically diverse Marburg viruses from Egyptian fruit batsJonathan S Towner
Special Pathogens Branch, Centers for Disease Control and Prevention, Atlanta, GA, USA
PLoS Pathog 5:e1000536. 2009..These data indicate common Egyptian fruit bats can represent a major natural reservoir and source of Marburg virus with potential for spillover into humans...
Monkeypox transmission and pathogenesis in prairie dogsJeannette Guarner
Infectious Disease Pathology Activity, Centers for Disease Control and Prevention, Mailstop G32, 1600 Clifton Road NE, Atlanta, GA 30333, USA
Emerg Infect Dis 10:426-31. 2004..Prairie dogs offer insights into transmission, pathogenesis, and new vaccine and treatment trials because they are susceptible to severe monkeypox infection...
Solid organ transplant-associated lymphocytic choriomeningitis, United States, 2011Adam MacNeil
Centers for Disease Control and Prevention, Atlanta, Georgia, USA
Emerg Infect Dis 18:1256-62. 2012..In this cluster, all recipients developed severe illness, but 2 survived. LCMV infection should be considered as a possible cause of severe posttransplant illness...
Imported spotted fever rickettsioses in United States travelers returning from Africa: a summary of cases confirmed by laboratory testing at the Centers for Disease Control and Prevention, 1999-2002Jennifer H McQuiston
Viral and Rickettsial Zoonoses Branch, and Infectious Disease Pathology Activity, Division of Viral and Rickettsial Diseases, National Center for Infectious Disease, Centers for Disease Control and Prevention, Atlanta, Georgia 30333, USA
Am J Trop Med Hyg 70:98-101. 2004....
Fatal malaria infection in travelers: novel immunohistochemical assays for the detection of Plasmodium falciparum in tissues and implications for pathogenesisGillian L Genrich
Infectious Disease Pathology and Malaria Branches, Centers for Disease Control and Prevention, Atlanta, Georgia 30333, USA
Am J Trop Med Hyg 76:251-9. 2007..vivax. Immunostaining patterns were predominately cytoplasmic and membranous. P. falciparum antigens were detected in a variety of organs but were most abundant in the blood vessels of brain, heart, and lung tissues...
Gulf Coast ticks (Amblyomma maculatum) and Rickettsia parkeri, United StatesJohn W Sumner
Infectious Disease Pathology Branch, Centers for Disease Control and Prevention, Atlanta, GA 30333, USA
Emerg Infect Dis 13:751-3. 2007..maculatum may be responsible for additional cases of R. parkeri rickettsiosis throughout much of its US range...
Flying squirrel-associated typhus, United StatesMary G Reynolds
Centers for Disease Control and Prevention, 1600 Clifton Road, Mail Stop G13, Atlanta, GA 30338, USA
Emerg Infect Dis 9:1341-3. 2003
Fatal Rocky Mountain spotted fever in the United States, 1999-2007F Scott Dahlgren
Rickettsial Zoonoses Branch, Division of Vectorborne Infectious Diseases, National Center for Emerging and Zoonotic Infectious Disease, Atlanta, Georgia, USA
Am J Trop Med Hyg 86:713-9. 2012..4). Delaying treatment of RMSF was also associated with increased deaths. These results may indicate a gap between recommendations and practice...
Rapid, simultaneous detection of Clostridium sordellii and Clostridium perfringens in archived tissues by a novel PCR-based microsphere assay: diagnostic implications for pregnancy-associated toxic shock syndrome casesJulu Bhatnagar
Infectious Diseases Pathology Branch, Division of High Consequence Pathogens and Pathology, Centers for Disease Control and Prevention, Atlanta, GA 30333, USA
Infect Dis Obstet Gynecol 2012:972845. 2012..The microsphere assay is a rapid, specific, and cost-effective method for the diagnosis of CTS and offers the advantage of simultaneous testing for C. sordellii and C. perfringens in FFPE tissues using a limited amount of DNA...
Human monkeypox infection: a family cluster in the midwestern United StatesJames J Sejvar
Division of Viral and Rickettsial Diseases, National Center for Infectious Diseases, Centers for Disease Control and Prevention, Atlanta, Georgia 30033, USA
J Infect Dis 190:1833-40. 2004..We describe a cluster of monkeypox in a family with a spectrum of clinical illness, including encephalitis, and outline the laboratory confirmation of monkeypox...
Diagnosis of influenza from respiratory autopsy tissues: detection of virus by real-time reverse transcription-PCR in 222 casesAmy M Denison
Infectious Diseases Pathology Branch, Centers for Disease Control and Prevention, Atlanta, Georgia, USA
J Mol Diagn 13:123-8. 2011..We also determined that testing of all available respiratory tissues is critical for optimal detection of influenza virus in postmortem tissues...
Isolation of Rickettsia parkeri and identification of a novel spotted fever group Rickettsia sp. from Gulf Coast ticks (Amblyomma maculatum) in the United StatesChristopher D Paddock
Infectious Diseases Pathology Branch, Centers for Disease Control and Prevention, Atlanta, Georgia 30333, USA
Appl Environ Microbiol 76:2689-96. 2010..This study considerably expanded the number of low-passage, A. maculatum-derived isolates of R. parkeri and characterized a second, sympatric Rickettsia sp. found in Gulf Coast ticks...
Adrenal gland hemorrhage in patients with fatal bacterial infectionsJeannette Guarner
Department of Pathology and Laboratory Medicine, Emory University School of Medicine, Atlanta, GA 30322, USA
Mod Pathol 21:1113-20. 2008..Although N. meningitidis is the most frequent bacteria associated with adrenal gland pathology, a broad collection of bacteria can also cause adrenal lesions...
Rocky Mountain spotted fever in Arizona: documentation of heavy environmental infestations of Rhipicephalus sanguineus at an endemic siteWilliam L Nicholson
Viral and Rickettsial Zoonoses Branch, Centers for Disease Control and Prevention, Mail Stop G 13, 1600 Clifton Road, Atlanta, GA 30333, USA
Ann N Y Acad Sci 1078:338-41. 2006..It is evident that under certain circumstances, this species does transmit Rickettsia rickettsii to humans and deserves reconsideration as a vector in other geographic areas...
Blastomycosis in man after kinkajou biteJulie R Harris
Centers for Disease Control and Prevention, Atlanta, Georgia 30333, USA
Emerg Infect Dis 17:268-70. 2011..When treating a patient with a recalcitrant infection and a history of an animal bite, early and complete animal necropsy and consideration of nonbacterial etiologies are needed...
Histopathologic spectrum and immunohistochemical diagnosis of amebic meningoencephalitisJeannette Guarner
Infectious Disease Pathology Branch, National Center for Infectious Diseases, Centers for Disease Control and Prevention, 1405 Clifton Road NE, Atlanta, GA 30322, USA
Mod Pathol 20:1230-7. 2007..The term amebic meningoencephalitis describes better the histopathologic findings than the currently used classification of primary amebic meningoencephalitis and granulomatous amebic encephalitis...
Pet rodents and fatal lymphocytic choriomeningitis in transplant patientsBrian R Amman
Centers for Disease Control and Prevention, Atlanta, Georgia 30333, USA
Emerg Infect Dis 13:719-25. 2007..This report details the animal traceback and the supporting laboratory investigations...
Histopathologic and immunohistochemical features of fatal influenza virus infection in children during the 2003-2004 seasonJeannette Guarner
Infectious Disease Pathology Activity, Centers for Disease Control and Prevention, Atlanta, GA 30333, USA
Clin Infect Dis 43:132-40. 2006..The Centers for Disease Control and Prevention enhanced national surveillance for influenza-associated deaths among children because of early reports of pediatric deaths during the 2003-2004 influenza season...
Clinicopathologic study and laboratory diagnosis of 23 cases with West Nile virus encephalomyelitisJeannette Guarner
Centers for Disease Control and Prevention, Atlanta, GA 30333, USA
Hum Pathol 35:983-90. 2004..Differences in the amount of viral antigen may be related to underlying medical conditions and length of survival. IHC can be an important diagnostic method, particularly during the 1st week of illness, when antigen levels are high...
Detection of Ehrlichia chaffeensis in adult and nymphal Amblyomma americanum (Acari: Ixodidae) ticks from Long Island, New YorkTonya R Mixson
Viral and Rickettsial Zoonoses Branch, Division of Viral and Rickettsial Disease, Centers for Disease Control and Prevention, Atlanta, GA 30333, USA
J Med Entomol 41:1104-10. 2004..chaffeensis is endemic to many areas of Long Island and that HME should be considered among the differential diagnoses of the many distinct tick-borne diseases that occur in this region...
Risk factors for lower respiratory tract infection death among infants in the United States, 1999-2004Rosalyn J Singleton
Alaska Native Tribal Health Consortium, Anchorage, Alaska, USA
Pediatrics 124:e768-76. 2009..To describe maternal and birth-related risk factors associated with lower respiratory tract infection (LRTI) deaths among infants...
Influenza-associated deaths among children in the United States, 2003-2004Niranjan Bhat
Epidemic Intelligence Service, Career Development Division, Office of Workforce and Career Development National Center for Infectious Diseases, Centers for Disease Control and Prevention, Atlanta, GA 30333, USA
N Engl J Med 353:2559-67. 2005..Although influenza is common among children, pediatric mortality related to laboratory-confirmed influenza has not been assessed nationally...
Infant and maternal risk factors for pertussis-related infant mortality in the United States, 1999 to 2004Dana L Haberling
Division of Viral and Rickettsial Diseases, National Center for Zoonotic, Vector Borne, and Enteric Diseases, Centers for Disease Control and Prevention, Atlanta, GA 30333, USA
Pediatr Infect Dis J 28:194-8. 2009..Infants aged <12 months have the highest rates of complications and death from pertussis of any age group. Factors that increase the risk of pertussis-related death in infants are not well defined...
A novel coronavirus associated with severe acute respiratory syndromeThomas G Ksiazek
Special Pathogens Branch, National Center for Infectious Diseases, Centers for Disease Control and Prevention, Atlanta, USA
N Engl J Med 348:1953-66. 2003..Because of the death of Dr. Carlo Urbani, we propose that our first isolate be named the Urbani strain of SARS-associated coronavirus...
Ehrlichia chaffeensis: a prototypical emerging pathogenChristopher D Paddock
Viral and Rickettsial Zoonoses Branch, Division of Viral and Rickettsial Diseases, National Center for Infectious Diseases, Centers for Disease Control and Prevention, Atlanta, Georgia 30333, USA
Clin Microbiol Rev 16:37-64. 2003..americanum, and improvements in confirmatory diagnostic methods, are also explored...
Transmission of rabies virus from an organ donor to four transplant recipientsArjun Srinivasan
Division of Healthcare Quality Promotion, National Center for Infectious Diseases, and the Epidemic Intelligence Service Branch, Centers for Disease Control and Prevention, Atlanta, USA
N Engl J Med 352:1103-11. 2005..CONCLUSIONS: This report documenting the transmission of rabies virus from an organ donor to multiple recipients underscores the challenges of preventing and detecting transmission of unusual pathogens through transplantation...
Assessing the magnitude of fatal Rocky Mountain spotted fever in the United States: comparison of two national data sourcesChristopher D Paddock
Viral and Rickettsial Zoonoses Branch, and Office of the Director, Division of Viral and Rickettsial Diseases, National Center for Infectious Diseases, Centers for Disease Control and Prevention, Atlanta, Georgia 30333, USA
Am J Trop Med Hyg 67:349-54. 2002....
The ascendancy of Amblyomma americanum as a vector of pathogens affecting humans in the United StatesJames E Childs
Viral and Rickettsial Zoonoses Branch, Division of Viral and Rickettsial Diseases, National Center for Infectious Diseases, Centers for Disease Control and Prevention, Atlanta, Georgia 30333, USA
Annu Rev Entomol 48:307-37. 2003....
Short report: concurrent Rocky Mountain spotted fever in a dog and its ownerChristopher D Paddock
Division of Viral and Rickettsial Diseases, Centers for Disease Control and Prevention, Atlanta, Georgia 30333, USA
Am J Trop Med Hyg 66:197-9. 2002..Previous reports of concurrent RMSF in dogs and their owners are reviewed, and the epidemiologic significance of this occurrence is discussed...
Rickettsia parkeri as a paradigm for multiple causes of tick-borne spotted fever in the western hemisphereChristopher D Paddock
Infectious Disease Pathology Activity, Division of Viral and Rickettsial Diseases, Centers for Disease Control and Prevention, Atlanta, GA 30333, USA
Ann N Y Acad Sci 1063:315-26. 2005..parkeri as a cause of disease in humans will hopefully encourage a closer examination for specific etiologies of tick-borne spotted fever rickettsioses in the United States and other countries of the Western Hemisphere...
Passive surveillance as an instrument to identify risk factors for fatal Rocky Mountain spotted fever: is there more to learn?James E Childs
Division of Viral and Rickettsial Diseases, National Center for Infectious Diseases, Centers for Disease Control and Prevention, Atlanta, Georgia 30333, USA
Am J Trop Med Hyg 66:450-7. 2002..Modified surveillance activities could focus on evaluating the risk for fatal RMSF among special populations, monitoring appropriate antibiotic use, and assessing new diagnostic tests...
Leptospirosis outbreak following severe flooding: a rapid assessment and mass prophylaxis campaign; Guyana, January-February 2005Amy M Dechet
Centers for Disease Control and Prevention, Atlanta, Georgia, United States of America
PLoS ONE 7:e39672. 2012..Rapid testing for the disease and large-scale interventions are necessary to identify and control infection. We describe a leptospirosis outbreak following severe flooding and a mass chemoprophylaxis campaign in Guyana...
Progressive ORF virus infection in a patient with lymphoma: successful treatment using imiquimodEdith R Lederman
Division of Viral and Rickettsial Diseases, Centers for Disease Control and Prevention, Atlanta, GA 30333, USA
Clin Infect Dis 44:e100-3. 2007..The patient's orf virus infection was successfully treated with topical imiquimod despite progression of her malignancy...
Clinical, epidemiologic, histopathologic and molecular features of an unexplained dermopathyMichele L Pearson
Division of TB Elimination, Centers for Disease Control and Prevention, Atlanta, Georgia, United States of America
PLoS ONE 7:e29908. 2012..We conducted an investigation of this unexplained dermopathy to characterize the clinical and epidemiologic features and explore potential etiologies...
Ischemic cardiac events during the Department of Health and Human Services Smallpox Vaccination Program, 2003David L Swerdlow
Smallpox Vaccine Adverse Events Monitoring and Response Activity, National Immunization Program, Centers for Disease Control and Prevention, Atlanta, Georgia, USA
Clin Infect Dis 46:S234-41. 2008..10; 95% PI, 3.5-15.7). After persons with >/=3 cardiac risk factors or known heart disease were deferred from vaccination, no ICEs were reported among an additional 6638 vaccinees...
Molecular heterogeneity of Ehrlichia chaffeensis isolates determined by sequence analysis of the 28-kilodalton outer membrane protein genes and other regions of the genomeChuanmin Cheng
Department of Diagnostic Medicine Pathobiology, College of Veterinary Medicine, Kansas State University, Manhattan, Kansas 66506, USA
Infect Immun 71:187-95. 2003..chaffeensis genome. Diversity in different genomic regions could be the result of a selection process or of independently evolved genes...
Increased detection of rickettsialpox in a New York City hospital following the anthrax outbreak of 2001: use of immunohistochemistry for the rapid confirmation of cases in an era of bioterrorismTamara Koss
Department of Dermatology, Columbia University College of Physicians and Surgeons, New York, NY 10032, USA
Arch Dermatol 139:1545-52. 2003..The cluster of cutaneous anthrax cases from bioterrorism in October 2001 likely heightened awareness of and concern for cutaneous eschars...
Predominance of Ehrlichia ewingii in Missouri dogsAllison M Liddell
Department of Internal Medicine, Washington University School of Medicine, St. Louis, Missouri, USA
J Clin Microbiol 41:4617-22. 2003..E. canis, a widely recognized agent of canine ehrlichiosis, was not detected in any animal. The finding of E. ewingii in asymptomatic dogs suggests that dogs could be a reservoir for this Ehrlichia species...
Reinfection with Ehrlichia chaffeensis in a liver transplant recipientAllison M Liddell
Department of Medicine, Washington University School of Medicine, St. Louis, MO, 63110, USA
Clin Infect Dis 34:1644-7. 2002..We report a case of reinfection with E. chaffeensis after a 2-year interval in a 56-year-old liver transplant recipient with frequent tick attachments...
Survey of ticks collected in Mississippi for Rickettsia, Ehrlichia, and Borrelia speciesJerome Goddard
Mississippi Department of Health, Jackson, MS 39215-1700, USA
J Vector Ecol 28:184-9. 2003..The significance of this finding remains undetermined...
Rocky Mountain spotted fever, PanamaDora Estripeaut
Hospital del Nino, Panama City, Panama
Emerg Infect Dis 13:1763-5. 2007..Molecular typing demonstrated strong relatedness of the isolate to strains of R. rickettsii from Central and South America...
Rickettsia parkeri infection and other spotted fevers in the United StatesDidier Raoult
N Engl J Med 353:626-7. 2005
Observations on distribution and seasonal activity of the Gulf Coast tick in MississippiJerome Goddard
Bureau of General Environmental Services, Mississippi Department of Health, P.O. Box 1700, Jackson, MS 39215, USA
J Med Entomol 42:176-9. 2005..Nymphs were collected during February through August, and larvae were collected once during each of June, September, and October. Small sample sizes of the immature stages precluded determination of their peak activity...
Rickettsia parkeri infection after tick bite, VirginiaTimothy J Whitman
US Navy Infectious Diseases Department, National Naval Medical Center, Bethesda, Maryland 20889, USA
Emerg Infect Dis 13:334-6. 2007..Rickettsia parkeri was detected and isolated from the eschar. This report represents the second documented case of R. parkeri rickettsiosis in a US serviceman in eastern Virginia...
A new arenavirus in a cluster of fatal transplant-associated diseasesGustavo Palacios
Center for Infection and Immunity, Mailman School of Public Health, Columbia University, New York, NY 10032, USA
N Engl J Med 358:991-8. 2008..Culture, polymerase-chain-reaction (PCR) and serologic assays, and oligonucleotide microarray analysis for a wide range of infectious agents were not informative...
Tick-borne rickettsioses around the world: emerging diseases challenging old conceptsPhilippe Parola
, CNRS UMR 6020, IFR 48, , , 13385 Marseille Cedex 5, France
Clin Microbiol Rev 18:719-56. 2005..We present here the tick-borne rickettsioses described through 2005 and focus on the epidemiological circumstances that have played a role in the emergence of the newly recognized diseases...
Transmission of lymphocytic choriomeningitis virus by organ transplantationStaci A Fischer
Rhode Island Hospital and Brown Medical School, Providence, USA
N Engl J Med 354:2235-49. 2006..One recipient, who received ribavirin and reduced levels of immunosuppressive therapy, survived. CONCLUSIONS: We document two clusters of LCMV infection transmitted through organ transplantation...
Pseudoepidemic of Q fever at an animal research facilityLisa A Conti
Florida Department of Health, Tallahassee, Florida, USA
Vector Borne Zoonotic Dis 4:343-350. 2004..This pseudoepidemic resulted from a lapse in laboratory quality control for testing. Similar errors can be avoided through standardization and improved review of laboratory procedures...
Fatal Rickettsia conorii subsp. israelensis infection, IsraelMiriam Weinberger
Infectious Diseases Unit, Assaf Harofeh Medical Center, Zerifin 70300, Israel
Emerg Infect Dis 14:821-4. 2008..israelensis in a traveler returning to Israel from India...
Fatal spotted fever rickettsiosis, KenyaJeremiah S Rutherford
United States Army Medical Research Unit, Nairobi, Kenya
Emerg Infect Dis 10:910-3. 2004..Immunohistochemical staining of skin, kidney, and liver demonstrated spotted fever group rickettsiae. The clinical findings, severity, and fatal outcome are most consistent with Rickettsia conorii infection...
Utility of the aged BALB/c mouse model to demonstrate prevention and control strategies for severe acute respiratory syndrome coronavirus (SARS-CoV)Leatrice N Vogel
Laboratory of Infectious Diseases, NIAID, NIH, Bethesda, MD 20892, USA
Vaccine 25:2173-9. 2007..This study validates the utility of the aged BALB/c mouse model for evaluation of the efficacy of vaccines and immunoprophylaxis...
Q fever endocarditis in HIV-infected patientMiguel G Madariaga
Division of Infectious Disease, Cook County Hospital, Rush Medical College, Chicago, IL 60612, USA
Emerg Infect Dis 10:501-4. 2004..We review the current literature on Q fever endocarditis, with an emphasis on the co-infection of HIV and Coxiella burnetii...
Rocky Mountain spotted fever: a clinician's dilemmaEdwin J Masters
Department of Pediatrics, St Francis Medical Center and Southeast Missouri Hospital, Cape Girardeau, MO, USA
Arch Intern Med 163:769-74. 2003..Early diagnosis and proper treatment save lives...
Rickettsialpox in a patient with HIV infectionScott Sanders
Department of Dermatology, Cornell University Weill Medical Center and Lincoln Hospital, Bronx, NY, USA
J Am Acad Dermatol 48:286-9. 2003..Rickettsialpox is easily treated and may resemble more serious cutaneous eruptions in patients infected with HIV. This diagnosis should be considered in immunocompromised city-dwellers, with fever and a papulovesicular rash...
Fatal case of Brazilian spotted fever confirmed by immunohistochemical staining and sequencing methods on fixed tissuesTatiana Rozental
Lab de Hantaviroses e Rickettsioses, Depto Virologia, Pav Rocha Lima 5 andar, Fiocruz Av Brasil, 4365, Manguinhos, Rio de Janeiro, RJ, Brazil CEP 21045 900
Ann N Y Acad Sci 1078:257-9. 2006..The authors describe the first characterization of Rickettsia rickettsii in a fatal case occurring in Rio de Janeiro State, Brazil...
