Research Topics
Species | Ramal MoonesingheSummaryAffiliation: Centers for Disease Control and Prevention Country: USA Publications
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Detail Information
Publications
Evaluation of family history as a risk factor and screening tool for detecting undiagnosed diabetes in a nationally representative survey populationSusan Hariri
Office of Workforce and Career Development, Centers for Disease Control and Prevention, Atlanta, Georgia, USA
Genet Med 8:752-9. 2006..CONCLUSIONS: There was a strong and proportional association between familial risk and undiagnosed diabetes, suggesting that a three-tiered assessment of familial diabetes risk may increase the effectiveness of diabetes screening...
Most published research findings are false-but a little replication goes a long wayRamal Moonesinghe
National Office of Public Health Genomics, Coordinating Center for Health Promotion, Centers for Disease Control and Prevention, Atlanta, Georgia, United States of America
PLoS Med 4:e28. 2007
Prevalence in the United States of selected candidate gene variants: Third National Health and Nutrition Examination Survey, 1991-1994Man Huei Chang
National Office of Public Health Genomics, Centers for Disease Control and Prevention, Atlanta, GA 30341, USA
Am J Epidemiol 169:54-66. 2009..These nationally representative data on allele frequency and genotype prevalence provide a valuable resource for future epidemiologic studies in public health in the United States...
The association between family history of asthma and the prevalence of asthma among US adults: National Health and Nutrition Examination Survey, 1999-2004Tiebin Liu
Coordinating Center for Health Promotion, Centers for Disease Control and Prevention, Atlanta, GA 30341, USA
Genet Med 11:323-8. 2009..To assess the overall prevalence of asthma and the association between family history of asthma and the prevalence of asthma among US adults...
Using lifetime risk estimates in personal genomic profiles: estimation of uncertaintyQuanhe Yang
Office of Public Health Genomics, Centers for Disease Control and Prevention, Atlanta, GA 30333, USA
Am J Hum Genet 85:786-800. 2009..Epidemiologic parameters involved in computation of disease risk have substantial uncertainty, and cumulative uncertainty should be properly recognized. Reliance on point estimates alone could be seriously misleading...
Estimating the contribution of genetic variants to difference in incidence of disease between population groupsRamal Moonesinghe
Office of Minority Health and Health Disparities, Centers for Disease Control and Prevention, Atlanta, GA 30341, USA
Eur J Hum Genet 20:831-6. 2012..Any estimate of genetic contribution to the disparity in incidence of disease between two populations at this stage seems to be an elusive goal...
Linear and non-linear associations of gonorrhea diagnosis rates with social determinants of healthRamal Moonesinghe
Centers for Disease Control and Prevention, National Center for HIV AIDS, Viral Hepatitis, STD, and TB Prevention, Atlanta, GA 30333, USA
Int J Environ Res Public Health 9:3149-65. 2012..With the availability of more SDH variables and methods that distinguish linear from non-linear associations, geographic area-based analysis of disease incidence and SDH can add value to public health prevention and control programs...
The effects on population health status of using dedicated property taxes to fund local public health agenciesPeggy A Honoré
Department of Community Health Sciences, University of Southern Mississippi, Hattiesburg, MS 39406, USA
BMC Public Health 11:471. 2011..We investigated for an association of locally dedicated property taxes to fund local public health agencies and improved health status in the eight states designated as the Mississippi Delta Region...
A Hardy-Weinberg equilibrium test for analyzing population genetic surveys with complex sample designsRamal Moonesinghe
Office of Minority Health and Health Disparities, 4770 Buford Highway, Mailstop E 67, Atlanta, GA 30341, USA
Am J Epidemiol 171:932-41. 2010....
Evaluation of the discriminative accuracy of genomic profiling in the prediction of common complex diseasesRamal Moonesinghe
Office of Minority Health and Health Disparities, Centers for Disease Control and Prevention, Mailstop E 67, 1600 Clifton Road, NE, Atlanta, GA 30333, USA
Eur J Hum Genet 18:485-9. 2010....
Discriminative accuracy of genomic profiling comparing multiplicative and additive risk modelsRamal Moonesinghe
Office of Minority Health and Health Disparities, Centers for Disease Control and Prevention, Atlanta, GA 30341, USA
Eur J Hum Genet 19:180-5. 2011..Unraveling the exact mode of biological interaction is important when effect sizes of genetic variants are moderate at the least, to prevent the incorrect estimation of risks...
The ACE I/D polymorphism in US adults: limited evidence of association with hypertension-related traits and sex-specific effects by race/ethnicityRenee M Ned
Office of Public Health Genomics, Centers for Disease Control and Prevention, Atlanta, Georgia, USA
Am J Hypertens 25:209-15. 2012..The evidence to date, however, on an association of this variant with blood pressure-related outcomes has been inconclusive...
Improvements in ability to detect undiagnosed diabetes by using information on family history among adults in the United StatesQuanhe Yang
Centers for Disease Control and Prevention, Atlanta, GA 30333, USA
Am J Epidemiol 171:1079-89. 2010..Study findings suggest that adding family history of diabetes can provide significant improvements in detecting undiagnosed diabetes in the US population. Further research is needed to validate the authors' findings...
Required sample size and nonreplicability thresholds for heterogeneous genetic associationsRamal Moonesinghe
National Office of Public Health Genomics, Coordinating Center for Health Promotion, Centers for Disease Control and Prevention, Atlanta, GA 30341, USA
Proc Natl Acad Sci U S A 105:617-22. 2008..Therefore, some true associations may not be practically possible to replicate with consistency, no matter how large studies are conducted. Efforts should be made to minimize between-study heterogeneity in targeted genetic effects...
Inflammation gene variants and susceptibility to albuminuria in the U.S. population: analysis in the Third National Health and Nutrition Examination Survey (NHANES III), 1991-1994Renee M Ned
Office of Public Health Genomics, Office of Surveillance, Epidemiology, and Laboratory Services, Centers for Disease Control and Prevention, Atlanta, GA, USA
BMC Med Genet 11:155. 2010..While the underlying etiology is unclear, chronic, low-grade inflammation is a suspected key factor. Genetic variants within genes involved in inflammatory processes may, therefore, contribute to the development of albuminuria...
Genomic medicine and racial/ethnic health disparities: promises, perils, and the challenges for health care and public health policyRamal Moonesinghe
Office of Minority Health and Health Disparities, Centers for Disease Control and Prevention, Atlanta, Georgia, USA
Ethn Dis 19:473-8. 2009....
Short report: Race and rickettsiae: a United States perspectiveF Scott Dahlgren
Rickettsial Zoonoses Branch, Division of Vectorborne Infectious Diseases, National Center for Emerging and Zoonotic Infectious Disease, Centers for Disease Control and Prevention, Atlanta, Georgia, USA
Am J Trop Med Hyg 85:1124-5. 2011..Determining the association between race and ethnicity with incidence of rickettsial infections requires targeted, active surveillance...
Rationale for regular reporting on health disparities and inequalities - United StatesBenedict I Truman
Epidemiology and Analysis Program Office, CDC, Atlanta, GA 30333, USA
MMWR Surveill Summ 60:3-10. 2011..S. federal laws and commonly used in the U.S. public health literature to refer to gaps in health between segments of the population...
