Genomes and Genes
Anita K McElroy
Affiliation: Centers for Disease Control and Prevention
- Rift Valley fever virus inhibits a pro-inflammatory response in experimentally infected human monocyte derived macrophages and a pro-inflammatory cytokine response may be associated with patient survival during natural infectionAnita K McElroy
Viral Special Pathogens Branch, Division of High Consequence Pathogens and Pathology, Centers for Disease Control, MS G14, Atlanta, GA 30333, USA
Virology 422:6-12. 2012..Finally, analysis of RVF patient samples demonstrated an association between a pro-inflammatory cytokine response and patient survival...
- Development of a RVFV ELISA that can distinguish infected from vaccinated animalsAnita K McElroy
Special Pathogens Branch, Division of Viral and Rickettsial Diseases, Centers for Disease Control and Prevention, Atlanta, GA 30333, USA
Virol J 6:125. 2009..However, the ability to distinguish infected from vaccinated animals is important for vaccine acceptance by national and international authorities, given regulations restricting movement and export of infected animals...
- Rift Valley fever virus clearance and protection from neurologic disease are dependent on CD4+ T cell and virus-specific antibody responsesKimberly A Dodd
Viral Special Pathogens Branch, Division of High Consequence Pathogens and Pathology, Centers for Disease Control and Prevention, Atlanta, Georgia, USA
J Virol 87:6161-71. 2013..Together, these results indicate CD4(+) T cells are critical determinants of RVFV pathogenesis and play an important role in preventing onset of neurologic disease...
- Rift Valley fever virus vaccine lacking the NSs and NSm genes is safe, nonteratogenic, and confers protection from viremia, pyrexia, and abortion following challenge in adult and pregnant sheepBrian H Bird
Viral Special Pathogens Branch, Division of High Consequence Pathogens and Pathology, Centers for Disease Control and Prevention, 1600 Clifton Road, MS G 14, Atlanta, GA 30329, USA
J Virol 85:12901-9. 2011..As expected, all 3 sham-vaccinated controls experienced viremia, fetal death, and abortion postchallenge. These results demonstrate that the ΔNSs-ΔNSm rRVFV vaccine is safe and nonteratogenic and confers high-level protection in sheep...