Linda K McDougal

Summary

Affiliation: Centers for Disease Control and Prevention
Country: USA

Publications

  1. pmc Pulsed-field gel electrophoresis typing of oxacillin-resistant Staphylococcus aureus isolates from the United States: establishing a national database
    Linda K McDougal
    Division of Healthcare Quality Promotion, Centers for Disease Control and Prevention, Atlanta, Georgia 30333, USA
    J Clin Microbiol 41:5113-20. 2003
  2. pmc Emergence of resistance among USA300 methicillin-resistant Staphylococcus aureus isolates causing invasive disease in the United States
    Linda K McDougal
    Division of Healthcare Quality Promotion G 08, Centers for Disease Control and Prevention, 1600 Clifton Rd NE, Atlanta, GA 30333, USA
    Antimicrob Agents Chemother 54:3804-11. 2010
  3. pmc Vancomycin-resistant Staphylococcus aureus isolates associated with Inc18-like vanA plasmids in Michigan
    Wenming Zhu
    Division of Healthcare Quality Promotion, Centers for Disease Control and Prevention, 1600 Clifton Rd, MS G08, Atlanta, GA 30333, USA
    Antimicrob Agents Chemother 52:452-7. 2008
  4. doi request reprint Changes in the prevalence of nasal colonization with Staphylococcus aureus in the United States, 2001-2004
    Rachel J Gorwitz
    National Center for Preparedness, Detection, and Control of Infectious Diseases, Centers for Disease Control and Prevention, Atlanta, GA 30333, USA
    J Infect Dis 197:1226-34. 2008
  5. ncbi request reprint Invasive methicillin-resistant Staphylococcus aureus infections in the United States
    R Monina Klevens
    Division of Healthcare Quality Promotion, Centers for Disease Control and Prevention, Atlanta, Georgia, USA
    JAMA 298:1763-71. 2007
  6. ncbi request reprint Prevalence of Staphylococcus aureus nasal colonization in the United States, 2001-2002
    Matthew J Kuehnert
    National Center for Infectious Diseases, Centers for Disease Control and Prevention, Atlanta, Georgia 30333, USA
    J Infect Dis 193:172-9. 2006
  7. pmc Vancomycin-resistant Staphylococcus aureus isolate from a patient in Pennsylvania
    Fred C Tenover
    Division of Healthcare Quality Promotion, Centers for Disease Control and Prevention, Atlanta, Georgia 30333, USA
    Antimicrob Agents Chemother 48:275-80. 2004
  8. pmc High-level vancomycin-resistant Staphylococcus aureus isolates associated with a polymicrobial biofilm
    Linda M Weigel
    NCID DHQP ELB MS G 08, Centers for Disease Control and Prevention, 1600 Clifton Road, N E, Atlanta, GA 30333, USA
    Antimicrob Agents Chemother 51:231-8. 2007
  9. pmc Characterization of a strain of community-associated methicillin-resistant Staphylococcus aureus widely disseminated in the United States
    Fred C Tenover
    Division of Healthcare Quality Promotion, Centers for Disease Control and Prevention, Atlanta, GA 30333, USA
    J Clin Microbiol 44:108-18. 2006
  10. pmc Multicenter study to determine disk diffusion and broth microdilution criteria for prediction of high- and low-level mupirocin resistance in Staphylococcus aureus
    Jana M Swenson
    Division of Healthcare Quality Promotion, Centers for Disease Control and Prevention, Atlanta, GA 30333, USA
    J Clin Microbiol 48:2469-75. 2010

Detail Information

Publications34

  1. pmc Pulsed-field gel electrophoresis typing of oxacillin-resistant Staphylococcus aureus isolates from the United States: establishing a national database
    Linda K McDougal
    Division of Healthcare Quality Promotion, Centers for Disease Control and Prevention, Atlanta, Georgia 30333, USA
    J Clin Microbiol 41:5113-20. 2003
    ..Noticeably absent from the U.S. database were isolates with the previously described Brazilian and EMRSA15 PFGE patterns. These data suggest that there are a limited number of ORSA genotypes present in the United States...
  2. pmc Emergence of resistance among USA300 methicillin-resistant Staphylococcus aureus isolates causing invasive disease in the United States
    Linda K McDougal
    Division of Healthcare Quality Promotion G 08, Centers for Disease Control and Prevention, 1600 Clifton Rd NE, Atlanta, GA 30333, USA
    Antimicrob Agents Chemother 54:3804-11. 2010
    ....
  3. pmc Vancomycin-resistant Staphylococcus aureus isolates associated with Inc18-like vanA plasmids in Michigan
    Wenming Zhu
    Division of Healthcare Quality Promotion, Centers for Disease Control and Prevention, 1600 Clifton Rd, MS G08, Atlanta, GA 30333, USA
    Antimicrob Agents Chemother 52:452-7. 2008
    ..An Inc18-like vanA plasmid was identified in the VRSA isolate from case patient 7. These findings suggest a role of Inc18-like plasmids as vanA donors...
  4. doi request reprint Changes in the prevalence of nasal colonization with Staphylococcus aureus in the United States, 2001-2004
    Rachel J Gorwitz
    National Center for Preparedness, Detection, and Control of Infectious Diseases, Centers for Disease Control and Prevention, Atlanta, GA 30333, USA
    J Infect Dis 197:1226-34. 2008
    ..Staphylococcus aureus is a common cause of infection, particularly in persons colonized by this organism. Virulent strains of methicillin-resistant S. aureus (MRSA) have emerged in the general community...
  5. ncbi request reprint Invasive methicillin-resistant Staphylococcus aureus infections in the United States
    R Monina Klevens
    Division of Healthcare Quality Promotion, Centers for Disease Control and Prevention, Atlanta, Georgia, USA
    JAMA 298:1763-71. 2007
    ..As the epidemiology of infections with methicillin-resistant Staphylococcus aureus (MRSA) changes, accurate information on the scope and magnitude of MRSA infections in the US population is needed...
  6. ncbi request reprint Prevalence of Staphylococcus aureus nasal colonization in the United States, 2001-2002
    Matthew J Kuehnert
    National Center for Infectious Diseases, Centers for Disease Control and Prevention, Atlanta, Georgia 30333, USA
    J Infect Dis 193:172-9. 2006
    ..Although methicillin-resistant S. aureus (MRSA) infection has become increasingly reported, population-based S. aureus and MRSA colonization estimates are lacking...
  7. pmc Vancomycin-resistant Staphylococcus aureus isolate from a patient in Pennsylvania
    Fred C Tenover
    Division of Healthcare Quality Promotion, Centers for Disease Control and Prevention, Atlanta, Georgia 30333, USA
    Antimicrob Agents Chemother 48:275-80. 2004
    ..The vanA sequence was identical to the vanA sequence present in Tn1546. A DNA probe for vanA hybridized to the 120-kb plasmid. This is the second VRSA isolate reported in the United States...
  8. pmc High-level vancomycin-resistant Staphylococcus aureus isolates associated with a polymicrobial biofilm
    Linda M Weigel
    NCID DHQP ELB MS G 08, Centers for Disease Control and Prevention, 1600 Clifton Road, N E, Atlanta, GA 30333, USA
    Antimicrob Agents Chemother 51:231-8. 2007
    ..The potential for interspecies transfer of antimicrobial resistance genes, including resistance to vancomycin, may be enhanced by the microenvironment of a biofilm...
  9. pmc Characterization of a strain of community-associated methicillin-resistant Staphylococcus aureus widely disseminated in the United States
    Fred C Tenover
    Division of Healthcare Quality Promotion, Centers for Disease Control and Prevention, Atlanta, GA 30333, USA
    J Clin Microbiol 44:108-18. 2006
    ..Comparative genomics between USA300-0114 and three other S. aureus lineages (USA100, USA400, and USA500) defined a set of USA300-0114-specific genes, which may facilitate the strain's pathogenesis within diverse environments...
  10. pmc Multicenter study to determine disk diffusion and broth microdilution criteria for prediction of high- and low-level mupirocin resistance in Staphylococcus aureus
    Jana M Swenson
    Division of Healthcare Quality Promotion, Centers for Disease Control and Prevention, Atlanta, GA 30333, USA
    J Clin Microbiol 48:2469-75. 2010
    ..Use of standardized MIC or disk tests could enable the detection of emerging high- and low-level mupirocin resistance in S. aureus...
  11. pmc Testing for induction of clindamycin resistance in erythromycin-resistant isolates of Staphylococcus aureus
    Christine D Steward
    Division of Healthcare Quality Promotion, Centers for Disease Control and Prevention, 1600 Clifton Road, NE, Atlanta, GA 30333, USA
    J Clin Microbiol 43:1716-21. 2005
    ..Thus, at present, disk diffusion is the preferred method for testing S. aureus isolates for inducible CLI resistance...
  12. pmc Methamphetamine use and methicillin-resistant Staphylococcus aureus skin infections
    Adam L Cohen
    Respiratory Diseases Brabch, Division of Bacterial Diseases, Centers for Disease Control and Prevention, Atlanta, Georgia 30333, USA
    Emerg Infect Dis 13:1707-13. 2007
    ..10, 95% confidence interval 1.55-16.79). MRSA caused most SSTIs in this population. Transmission of MRSA may be occurring among methamphetamine users in this community...
  13. pmc Characterization of Staphylococcus aureus isolates from nasal cultures collected from individuals in the United States in 2001 to 2004
    Fred C Tenover
    Division of Healthcare Quality Promotion G 08, Centers for Disease Control and Prevention, 1600 Clifton Rd, NE, Atlanta, GA 30333, USA
    J Clin Microbiol 46:2837-41. 2008
    ..In contrast, the proportions of MRSA isolates that were susceptible to chloramphenicol, clindamycin, and erythromycin were lower in 2003 and 2004 than in 2001 and 2002, although none of these differences was statistically significant...
  14. pmc Dissemination of an Enterococcus Inc18-Like vanA plasmid associated with vancomycin-resistant Staphylococcus aureus
    Wenming Zhu
    Division of Healthcare Quality Promotion1 and Division of Scientific Resources, 4 Centers for Disease Control and Prevention, MS G08, 1600 Clifton Road, Atlanta, Georgia 30333, USA
    Antimicrob Agents Chemother 54:4314-20. 2010
    ..Although VRE isolates with the VRSA-associated Inc18-like vanA plasmid were more common in Michigan, they remain rare. Periodic surveillance of VRE isolates for the plasmid may be useful in predicting the occurrence of VRSA...
  15. ncbi request reprint Emergence of community-associated methicillin resistant Staphylococcus aureus in Hawaii, 2001-2003
    Concepcion F Estivariz
    Division of Healthcare Quality Promotion, National Center for Infectious Diseases, Centers for Disease Control and Prevention, US Department of Health and Human Services, Atlanta, GA 30333, USA
    J Infect 54:349-57. 2007
    ..We conducted a retrospective study to determine trends and characteristics of community-associated methicillin-resistant Staphylococcus aureus (CA-MRSA) in Hawaii...
  16. ncbi request reprint Genetic analysis of a high-level vancomycin-resistant isolate of Staphylococcus aureus
    Linda M Weigel
    Division of Healthcare Quality Promotion, Centers for Disease Control and Prevention, Atlanta, GA 30333, USA
    Science 302:1569-71. 2003
    ..Genetic analyses suggest that the long-anticipated transfer of vancomycin resistance to a methicillin-resistant S. aureus occurred in vivo by interspecies transfer of Tn1546 from a co-isolate of Enterococcus faecalis...
  17. pmc Severe community-acquired pneumonia due to Staphylococcus aureus, 2003-04 influenza season
    Jeffrey C Hageman
    Centers for Disease Control and Prevention, Atlanta, Georgia 30333, USA
    Emerg Infect Dis 12:894-9. 2006
    ..In communities with a high prevalence of MRSA, empiric therapy of severe CAP during periods of high influenza activity should include consideration for MRSA...
  18. pmc Multiple-locus variable-number tandem-repeat assay analysis of methicillin-resistant Staphylococcus aureus strains
    Fred C Tenover
    Division of Healthcare Quality Promotion G 08, Centers for Disease Control and Prevention, 1600 Clifton Rd NE, Atlanta, GA 30333, USA
    J Clin Microbiol 45:2215-9. 2007
    ..The ability of MLVA to differentiate among strains that are indistinguishable by PFGE may be of epidemiologic value and warrants further study...
  19. ncbi request reprint Risk factors for colonization with methicillin-resistant Staphylococcus aureus (MRSA) in patients admitted to an urban hospital: emergence of community-associated MRSA nasal carriage
    Alicia I Hidron
    Division of Infectious Diseases, Department of Medicine, Emory University School of Medicine, Atlanta, GA 30303, USA
    Clin Infect Dis 41:159-66. 2005
    ..We determined the prevalence of and risk factors for MRSA colonization at the time of hospital admission among patients cared for at a public urban hospital...
  20. pmc Community strains of methicillin-resistant Staphylococcus aureus as potential cause of healthcare-associated infections, Uruguay, 2002-2004
    Stephen R Benoit
    Centers for Disease Control and Prevention, Atlanta, Georgia 30333, USA
    Emerg Infect Dis 14:1216-23. 2008
    ..In addition, CA-MRSA appears to cause healthcare-onset infections, a finding that emphasizes the need for infection control measures to prevent transmission within healthcare settings...
  21. pmc Detection of inducible clindamycin resistance in staphylococci by broth microdilution using erythromycin-clindamycin combination wells
    Jana M Swenson
    Antimicrobial Resistance Team, Division of Healthcare Quality Promotion, Centers for Disease Control and Prevention, Atlanta, GA 30333, USA
    J Clin Microbiol 45:3954-7. 2007
    ..After a 24-h incubation, the ERY-CC combinations of 4 and 0.5, 6 and 1, and 8 and 1.5 microg/ml correlated well with the D-zone test...
  22. pmc Community-associated methicillin-resistant Staphylococcus aureus and healthcare risk factors
    R Monina Klevens
    Centers for Disease Control and Prevention, Atlanta, Georgia 30333, USA
    Emerg Infect Dis 12:1991-3. 2006
    ..Of patients with HRFs, 18%-28% had a "community-associated" strain, primarily USA300; of patients without HRFs, 26% had a "healthcare-associated" strain, typically USA100...
  23. ncbi request reprint Epidemiological and microbiological characterization of infections caused by Staphylococcus aureus with reduced susceptibility to vancomycin, United States, 1997-2001
    Scott K Fridkin
    Division of Healthcare Quality Promotion, National Center for Infectious Diseases, Centers for Disease Control and Prevention, Atlanta, GA 30333, USA
    Clin Infect Dis 36:429-39. 2003
    ..Independent risk factors for being a case patient included antecedent vancomycin use and prior oxacillin-resistant S. aureus infection 2 or 3 months before the current infection...
  24. ncbi request reprint A clone of methicillin-resistant Staphylococcus aureus among professional football players
    Sophia V Kazakova
    Division of Healthcare Quality Promotion, National Center for Infectious Diseases, Atlanta, GA 30333, USA
    N Engl J Med 352:468-75. 2005
    ..We investigated an outbreak of abscesses due to MRSA among members of a professional football team and examined the transmission and microbiologic characteristics of the outbreak strain...
  25. pmc Methicillin-resistant Staphylococcus aureus colonization of the groin and risk for clinical infection among HIV-infected adults
    Philip J Peters
    Division of HIV AIDS Prevention, Centers for Disease Control and Prevention, Atlanta, Georgia 30333, USA
    Emerg Infect Dis 19:623-9. 2013
    ..8) and a history of MRSA infection (adjusted risk ratio 3.1). MRSA prevention strategies that can effectively prevent or eliminate groin colonization are likely necessary to reduce clinical infections in this population...
  26. ncbi request reprint Macrolide-resistant pneumococcal endocarditis and epidural abscess that develop during erythromycin therapy
    Jay C Butler
    Arctic Investigations Program, National Center for Infectious Diseases, Centers for Disease Control and Prevention, Anchorage, Alaska 99508, USA
    Clin Infect Dis 36:e19-25. 2003
    ..Clinicians should be alert to the possibility of the emergence of resistance during macrolide therapy for community-acquired pneumonia, particularly if suppurative complications of pneumococcal infection are suspected...
  27. pmc Epidemiologic distribution of the arginine catabolic mobile element among selected methicillin-resistant and methicillin-susceptible Staphylococcus aureus isolates
    Richard V Goering
    Department of Medical Microbiology and Immunology, Creighton University School of Medicine, Omaha, NE 68178, USA
    J Clin Microbiol 45:1981-4. 2007
    ..arcA was also detected in selected methicillin-susceptible USA300 and methicillin-resistant USA100 isolates. DNA sequence analysis confirmed the integration of ACME in orfX...
  28. ncbi request reprint Emergence of multidrug-resistant, community-associated, methicillin-resistant Staphylococcus aureus clone USA300 in men who have sex with men
    Binh An Diep
    University of California, San Francisco, San Francisco, CA 94110, USA
    Ann Intern Med 148:249-57. 2008
    ..Infection with multidrug-resistant, community-associated, methicillin-resistant Staphylococcus aureus (MRSA) has been reported but seems to be isolated...
  29. pmc High frequencies of clindamycin and tetracycline resistance in methicillin-resistant Staphylococcus aureus pulsed-field type USA300 isolates collected at a Boston ambulatory health center
    Linda L Han
    State Laboratory Institute, 305 South St, Jamaica Plain, MA 02130, USA
    J Clin Microbiol 45:1350-2. 2007
    ..The clindamycin, tetracycline, and mupirocin resistance genes identified in these isolates are commonly associated with plasmids...
  30. ncbi request reprint Methicillin-resistant S. aureus infections among patients in the emergency department
    Gregory J Moran
    Department of Emergency Medicine, Olive View UCLA Medical Center, Sylmar, Calif 91342, USA
    N Engl J Med 355:666-74. 2006
    ..Methicillin-resistant Staphylococcus aureus (MRSA) is increasingly recognized in infections among persons in the community without established risk factors for MRSA...
  31. ncbi request reprint Re-emergence of early pandemic Staphylococcus aureus as a community-acquired meticillin-resistant clone
    D Ashley Robinson
    Department of Biology and Biochemistry, University of Bath, Bath, UK
    Lancet 365:1256-8. 2005
    ....
  32. ncbi request reprint Emergence of community-associated methicillin-resistant Staphylococcus aureus at a Memphis, Tennessee Children's Hospital
    Steven C Buckingham
    Department of Pediatrics, University of Tennessee Health Science Center, Memphis, TN, USA
    Pediatr Infect Dis J 23:619-24. 2004
    ..An epidemiologic investigation was performed because of a perceived increase in infections caused by community-associated methicillin-resistant Staphylococcus aureus (MRSA) among children in the greater Memphis area...
  33. ncbi request reprint Vancomycin-resistant Staphylococcus aureus in the absence of vancomycin exposure
    Cynthia J Whitener
    The Penn State Milton S Hershey Medical Center, Hershey, Pennsylvania 17033, USA
    Clin Infect Dis 38:1049-55. 2004
    ..For clinical and public health reasons, it is essential that microbiology laboratories adequately test for vancomycin-resistance in S. aureus...
  34. pmc Rapid multiplex PCR assay for identification of USA300 community-associated methicillin-resistant Staphylococcus aureus isolates
    Kristin K Bonnstetter
    Department of Medical Microbiology and Immunology, Creighton University School of Medicine, Omaha, NE 68178, USA
    J Clin Microbiol 45:141-6. 2007
    ..Multiplex results were 100% concordant with DNA sequencing, suggesting that the method has promise as a means of rapidly identifying USA300 isolates...