Research Topics

Taronna R Maines


Affiliation: Centers for Disease Control and Prevention
Country: USA


  1. Pulit Penaloza J, Jones J, Sun X, Jang Y, Thor S, Belser J, et al. Antigenically Diverse Swine Origin H1N1 Variant Influenza Viruses Exhibit Differential Ferret Pathogenesis and Transmission Phenotypes. J Virol. 2018;92: pubmed publisher
  2. Zeng H, Goldsmith C, Kumar A, Belser J, Sun X, Pappas C, et al. Tropism and Infectivity of a Seasonal A(H1N1) and a Highly Pathogenic Avian A(H5N1) Influenza Virus in Primary Differentiated Ferret Nasal Epithelial Cell Cultures. J Virol. 2019;: pubmed publisher
    ..Our findings offer significant insight into this first line defense against influenza virus infection and provide a model for the evaluation of emerging influenza viruses in a well-controlled in vitro environmental setting. ..
  3. Pulit Penaloza J, Belser J, Tumpey T, Maines T. Swine-origin H1 influenza viruses isolated from humans exhibit sustained infectivity in an aerosol state. Appl Environ Microbiol. 2019;: pubmed publisher
    ..Determination of molecular markers that affect longevity of airborne influenza viruses will improve our ability to quickly identify emerging strains that present the greatest threat to public health. ..
  4. Sun X, Belser J, Pappas C, Pulit Penaloza J, Brock N, Zeng H, et al. Risk Assessment of Fifth-Wave H7N9 Influenza A Viruses in Mammalian Models. J Virol. 2019;93: pubmed publisher
    ..Although the fifth-wave H7N9 viruses have not yet gained the ability to transmit efficiently by air, continuous surveillance and risk assessment remain essential parts of our pandemic preparedness efforts. ..
  5. Pulit Penaloza J, Pappas C, Belser J, Sun X, Brock N, Zeng H, et al. Comparative In Vitro and In Vivo Analysis of H1N1 and H1N2 Variant Influenza Viruses Isolated from Humans between 2011 and 2016. J Virol. 2018;92: pubmed publisher
    ..This investigation highlights the need for close monitoring of emerging variant influenza viruses for molecular changes that could facilitate efficient transmission among humans. ..
  6. Sun X, Pulit Penaloza J, Belser J, Pappas C, Pearce M, Brock N, et al. Pathogenesis and Transmission of Genetically Diverse Swine-Origin H3N2 Variant Influenza A Viruses from Multiple Lineages Isolated in the United States, 2011-2016. J Virol. 2018;92: pubmed publisher
    ..Extensive surveillance and risk assessment of H3N2v viruses should continue to be an essential component of our pandemic preparedness strategy. ..
  7. Sun X, Belser J, Pulit Penaloza J, Zeng H, Lewis A, Shieh W, et al. Pathogenesis and Transmission Assessments of Two H7N8 Influenza A Viruses Recently Isolated from Turkey Farms in Indiana Using Mouse and Ferret Models. J Virol. 2016;90:10936-10944 pubmed publisher
    ..Our findings offer important insight into the potential for emerging H7 avian influenza viruses to acquire the ability to cause disease and transmit among mammals. ..
  8. Belser J, Pulit Penaloza J, Sun X, Brock N, Pappas C, Creager H, et al. A Novel A(H7N2) Influenza Virus Isolated from a Veterinarian Caring for Cats in a New York City Animal Shelter Causes Mild Disease and Transmits Poorly in the Ferret Model. J Virol. 2017;91: pubmed publisher
    ..These data highlight the promiscuity of influenza viruses and the need for diligent surveillance across multiple species to quickly identify an emerging strain with pandemic potential. ..