J Y Ma

Summary

Affiliation: Centers for Disease Control and Prevention
Country: USA

Publications

  1. pmc Inhalation exposure of rats to asphalt fumes generated at paving temperatures alters pulmonary xenobiotic metabolism pathways without lung injury
    Jane Y C Ma
    Health Effects Laboratory Division, National Institute for Occupational Safety and Health, Morgantown, West Virginia 26505 2888, USA
    Environ Health Perspect 111:1215-21. 2003
  2. doi request reprint Induction of pulmonary fibrosis by cerium oxide nanoparticles
    Jane Y Ma
    Health Effects Laboratory Division, National Institute for Occupational Safety and Health, Morgantown, WV 26505, USA
    Toxicol Appl Pharmacol 262:255-64. 2012
  3. doi request reprint Cerium oxide nanoparticle-induced pulmonary inflammation and alveolar macrophage functional change in rats
    Jane Y Ma
    Health Effects Laboratory Division, National Institute for Occupational Safety and Health, Morgantown, West Virginia 26505 2888, USA
    Nanotoxicology 5:312-25. 2011
  4. ncbi request reprint Effects of asphalt fume condensate exposure on acute pulmonary responses
    J Y Ma
    Health Effects Laboratory Division, National Institute for Occupational Safety and Health, Morgantown, West Virginia 26505 2888, USA
    Arch Toxicol 74:452-9. 2000
  5. pmc Diesel exhaust particles suppress macrophage function and slow the pulmonary clearance of Listeria monocytogenes in rats
    H M Yang
    Health Effects Laboratory Division, National Institute for Occupational Safety and Health, Morgantown, West Virginia 26505, USA
    Environ Health Perspect 109:515-21. 2001
  6. ncbi request reprint Subchronic silica exposure enhances respiratory defense mechanisms and the pulmonary clearance of Listeria monocytogenes in rats
    J M Antonini
    Health Effects Laboratory Division, National Institute for Occupational Safety and Health, 1095 Willowdale Road, Morgantown, WV 26505, USA
    Inhal Toxicol 12:1017-36. 2000
  7. pmc Augmentation of pulmonary reactions to quartz inhalation by trace amounts of iron-containing particles
    V Castranova
    Health Effects Laboratory Division, National Institute for Occupational Safety and Health, Morgantown, West Virginia 26505, USA
    Environ Health Perspect 105:1319-24. 1997
  8. ncbi request reprint Effect of age on respiratory defense mechanisms: pulmonary bacterial clearance in Fischer 344 rats after intratracheal instillation of Listeria monocytogenes
    J M Antonini
    Health Effects Laboratory Division, National Institute for Occupational Safety and Health, Morgantown, WV 26505, USA
    Chest 120:240-9. 2001
  9. ncbi request reprint Comparative pulmonary toxicity of 6 abrasive blasting agents
    A F Hubbs
    Health Effects Laboratory Division, National Institute for Occupational Safety and Health, Centers for Disease Control and Prevention, 1095 Willowdale Road, Morgantown, West Virginia 26505, USA
    Toxicol Sci 61:135-43. 2001
  10. pmc Effect of exposure to diesel exhaust particles on the susceptibility of the lung to infection
    V Castranova
    National Institute for Occupational Safety and Health, Morgantown, West Virginia 26505, USA
    Environ Health Perspect 109:609-12. 2001

Collaborators

Detail Information

Publications11

  1. pmc Inhalation exposure of rats to asphalt fumes generated at paving temperatures alters pulmonary xenobiotic metabolism pathways without lung injury
    Jane Y C Ma
    Health Effects Laboratory Division, National Institute for Occupational Safety and Health, Morgantown, West Virginia 26505 2888, USA
    Environ Health Perspect 111:1215-21. 2003
    ..This induction of CYP1A1 and QR with the concomitant down-regulation of CYP2B1 after asphalt fume exposure could alter PAH metabolism and may lead to potential toxic effects in the lung...
  2. doi request reprint Induction of pulmonary fibrosis by cerium oxide nanoparticles
    Jane Y Ma
    Health Effects Laboratory Division, National Institute for Occupational Safety and Health, Morgantown, WV 26505, USA
    Toxicol Appl Pharmacol 262:255-64. 2012
    ..5mg/kg CeO(2) and euthanized at 28 days post-exposure. Collectively, our studies show that CeO(2) induced fibrotic lung injury in rats, suggesting it may cause potential health effects...
  3. doi request reprint Cerium oxide nanoparticle-induced pulmonary inflammation and alveolar macrophage functional change in rats
    Jane Y Ma
    Health Effects Laboratory Division, National Institute for Occupational Safety and Health, Morgantown, West Virginia 26505 2888, USA
    Nanotoxicology 5:312-25. 2011
    ..CeO2 induced inflammation, cytotoxicity, air/blood barrier damage, and phospholipidosis with enlarged AM. Thus, CeO2 induced lung inflammation and injury in lungs which may lead to fibrosis...
  4. ncbi request reprint Effects of asphalt fume condensate exposure on acute pulmonary responses
    J Y Ma
    Health Effects Laboratory Division, National Institute for Occupational Safety and Health, Morgantown, West Virginia 26505 2888, USA
    Arch Toxicol 74:452-9. 2000
    ..The present study was carried out to characterize the effects of in vitro exposure to paving asphalt fume condensate (AFC) on alveolar macrophage (AM) functions and to monitor acute pulmonary responses to in vivo AFC exposure in rats...
  5. pmc Diesel exhaust particles suppress macrophage function and slow the pulmonary clearance of Listeria monocytogenes in rats
    H M Yang
    Health Effects Laboratory Division, National Institute for Occupational Safety and Health, Morgantown, West Virginia 26505, USA
    Environ Health Perspect 109:515-21. 2001
    ..This DEP-induced suppression is caused partially by chemicals adsorbed onto the carbon core of DEP, because impaired macrophage function and decreased Listeria clearance were not observed following exposure to CB...
  6. ncbi request reprint Subchronic silica exposure enhances respiratory defense mechanisms and the pulmonary clearance of Listeria monocytogenes in rats
    J M Antonini
    Health Effects Laboratory Division, National Institute for Occupational Safety and Health, 1095 Willowdale Road, Morgantown, WV 26505, USA
    Inhal Toxicol 12:1017-36. 2000
    ..These elevations in pulmonary immune response are likely responsible for the increase in pulmonary clearance of L. monocytogenes observed with preexposure to silica...
  7. pmc Augmentation of pulmonary reactions to quartz inhalation by trace amounts of iron-containing particles
    V Castranova
    Health Effects Laboratory Division, National Institute for Occupational Safety and Health, Morgantown, West Virginia 26505, USA
    Environ Health Perspect 105:1319-24. 1997
    ..These results suggest that inhalation of freshly fractured quartz contaminated with trace levels of Fe may be more pathogenic than inhalation of quartz alone...
  8. ncbi request reprint Effect of age on respiratory defense mechanisms: pulmonary bacterial clearance in Fischer 344 rats after intratracheal instillation of Listeria monocytogenes
    J M Antonini
    Health Effects Laboratory Division, National Institute for Occupational Safety and Health, Morgantown, WV 26505, USA
    Chest 120:240-9. 2001
    ..To examine the lung defense mechanisms of both young and aged rats before and after pulmonary challenge with a bacterial pathogen...
  9. ncbi request reprint Comparative pulmonary toxicity of 6 abrasive blasting agents
    A F Hubbs
    Health Effects Laboratory Division, National Institute for Occupational Safety and Health, Centers for Disease Control and Prevention, 1095 Willowdale Road, Morgantown, West Virginia 26505, USA
    Toxicol Sci 61:135-43. 2001
    ..In contrast, specular hematite did not significantly elevate LDH or PMN levels and did not stimulate macrophage activity 4 weeks postexposure...
  10. pmc Effect of exposure to diesel exhaust particles on the susceptibility of the lung to infection
    V Castranova
    National Institute for Occupational Safety and Health, Morgantown, West Virginia 26505, USA
    Environ Health Perspect 109:609-12. 2001
    ..This inhibitory effect appears to be due to adsorbed organic chemicals rather than the carbonaceous core of the diesel particles...
  11. ncbi request reprint Pulmonary microsomal metabolism of benzo[a]pyrene following exposure of rats to silica
    P R Miles
    Division of Respiratory Disease Studies, National Institute for Occupational Safety, Morgantown, WV 26505, USA
    J Toxicol Environ Health 48:501-14. 1996
    ..5-fold. These results demonstrate that exposure of rats to silica may alter the capacity of the lungs to metabolize benzo[a]pyrene, and the greatest effect seems to be enhanced accumulation of BaP 7,8-diol and the BaP quinones...