Research Topics
| Carolina LuquezSummaryAffiliation: Centers for Disease Control and Prevention Country: USA Publications
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Detail Information
Publications
Genetic diversity among Clostridium botulinum strains harboring bont/A2 and bont/A3 genesCarolina Luquez
Enteric Diseases Laboratory Branch, Centers for Disease Control and Prevention, Atlanta, Georgia, USA
Appl Environ Microbiol 78:8712-8. 2012..Four groups of strains shared a similarity of at least 95% by PFGE; the largest group included 21 out of 46 strains. The strains analyzed in this study showed relatively limited genetic diversity using either MLST or PFGE...
Characterization of two virulent phages of Lactobacillus plantarumMariángeles Briggiler Marcó
Instituto de Lactología Industrial UNL CONICET, Facultad de Ingenieria Quimica, Santa Fe, Argentina
Appl Environ Microbiol 78:8719-34. 2012..Protein analysis revealed 13 (phage B1) and 9 (phage B2) structural proteins. To our knowledge, this is the first report describing such high identity between phage genomes infecting different genera of lactic acid bacteria...
Neurotoxin gene clusters in Clostridium botulinum type Ab strainsCarolina Luquez
Enteric Diseases Laboratory Branch, Centers for Disease Control and Prevention, Atlanta, Georgia 30333, USA
Appl Environ Microbiol 75:6094-101. 2009..The type Ab strains examined in this study had differences in their toxin gene cluster compositions and bont/A and bont/B nucleotide sequences, suggesting that they may have arisen from separate recombination events...
First report worldwide of an infant botulism case due to Clostridium botulinum type ECarolina Luquez
Centers for Disease Control and Prevention, 1600 Clifton Road, MS G 29, Atlanta, GA 30329, USA
J Clin Microbiol 48:326-8. 2010..Infant botulism type E cases have been associated with neurotoxigenic strains of C. butyricum. We report the first infant botulism case due to C. botulinum type E worldwide...
Detection and differentiation of Clostridium botulinum type A strains using a focused DNA microarrayBrian H Raphael
Enteric Diseases Laboratory Branch, Centers for Disease Control and Prevention, Atlanta, GA 30329, USA
Mol Cell Probes 24:146-53. 2010..The focused microarray format provides a rapid approach for neurotoxin gene detection and preliminary determination of the relatedness of strains isolated from different sources...
Sequence diversity of genes encoding botulinum neurotoxin type FBrian H Raphael
Centers for Disease Control and Prevention, Atlanta, GA 30329, USA
Appl Environ Microbiol 76:4805-12. 2010..These results demonstrate that extensive nucleotide diversity exists among genes encoding type F neurotoxins from strains with different phylogenetic backgrounds and from various geographical sources...
Genetic homogeneity of Clostridium botulinum type A1 strains with unique toxin gene clustersBrian H Raphael
Enteric Diseases Laboratory Branch, Centers for Disease Control and Prevention, 1600 Clifton Road, Atlanta, GA 30333, USA
Appl Environ Microbiol 74:4390-7. 2008..These results demonstrate surprising genomic homogeneity among a cluster of unique C. botulinum type A strains of diverse origin...
An alternative in vivo method to refine the mouse bioassay for botulinum toxin detectionTemeri D Wilder-Kofie
Division of Scientific Resources, National Center for Emerging and Zoonotic Infectious Diseases, Centers for Disease Control and Prevention, Atlanta, Georgia, USA
Comp Med 61:235-42. 2011..These results suggest that the mouse toe-spread reflex model may be a more humane alternative to the current mouse bioassay for laboratory investigations of botulism...
Analysis of a unique Clostridium botulinum strain from the Southern hemisphere producing a novel type E botulinum neurotoxin subtypeBrian H Raphael
Centers for Disease Control and Prevention, Atlanta, GA 30329, USA
BMC Microbiol 12:245. 2012..Previous studies showed that the amino acid sequences of BoNT/E produced by various strains differ by < 6% and that the type E neurotoxin gene cluster inserts into the rarA operon...
Initial recovery and rebound of type f intestinal colonization botulism after administration of investigational heptavalent botulinum antitoxinRyan P Fagan
Division of Foodborne, Waterborne, and Environmental Diseases, National Center for Emerging and Zoonotic Infectious Diseases, US Centers for Disease Control and Prevention, Atlanta, Georgia, USA
Clin Infect Dis 53:e125-8. 2011..Rebound botulism after antitoxin administration is not previously documented but occurred in our patient 10 days after HBAT administration...
