Carolina Luquez

Summary

Affiliation: Centers for Disease Control and Prevention
Country: USA

Publications

  1. pmc First report worldwide of an infant botulism case due to Clostridium botulinum type E
    Carolina Luquez
    Centers for Disease Control and Prevention, 1600 Clifton Road, MS G 29, Atlanta, GA 30329, USA
    J Clin Microbiol 48:326-8. 2010
  2. doi request reprint Molecular subtyping of Clostridium botulinum by pulsed-field gel electrophoresis
    Carolina Luquez
    Enteric Diseases Laboratory Branch, Centers for Disease Control and Prevention, 1600 Clifton Road, MS G 29, Atlanta, GA, 30329, USA
    Methods Mol Biol 1301:103-13. 2015
  3. pmc Genetic diversity among Clostridium botulinum strains harboring bont/A2 and bont/A3 genes
    Carolina Luquez
    Enteric Diseases Laboratory Branch, Centers for Disease Control and Prevention, Atlanta, Georgia, USA
    Appl Environ Microbiol 78:8712-8. 2012
  4. pmc Characterization of two virulent phages of Lactobacillus plantarum
    Mariángeles Briggiler Marcó
    Instituto de Lactología Industrial UNL CONICET, Facultad de Ingenieria Quimica, Santa Fe, Argentina
    Appl Environ Microbiol 78:8719-34. 2012
  5. pmc Neurotoxin gene clusters in Clostridium botulinum type Ab strains
    Carolina Luquez
    Enteric Diseases Laboratory Branch, Centers for Disease Control and Prevention, Atlanta, Georgia 30333, USA
    Appl Environ Microbiol 75:6094-101. 2009
  6. pmc Analysis of a unique Clostridium botulinum strain from the Southern hemisphere producing a novel type E botulinum neurotoxin subtype
    Brian H Raphael
    Centers for Disease Control and Prevention, Atlanta, GA 30329, USA
    BMC Microbiol 12:245. 2012
  7. doi request reprint Detection and differentiation of Clostridium botulinum type A strains using a focused DNA microarray
    Brian H Raphael
    Enteric Diseases Laboratory Branch, Centers for Disease Control and Prevention, Atlanta, GA 30329, USA
    Mol Cell Probes 24:146-53. 2010
  8. pmc Sequence diversity of genes encoding botulinum neurotoxin type F
    Brian H Raphael
    Centers for Disease Control and Prevention, Atlanta, GA 30329, USA
    Appl Environ Microbiol 76:4805-12. 2010
  9. pmc Clostridium botulinum strains producing BoNT/F4 or BoNT/F5
    Brian H Raphael
    Centers for Disease Control and Prevention, Atlanta, Georgia, USA
    Appl Environ Microbiol 80:3250-7. 2014
  10. doi request reprint A Novel Botulinum Neurotoxin, Previously Reported as Serotype H, Has a Hybrid-Like Structure With Regions of Similarity to the Structures of Serotypes A and F and Is Neutralized With Serotype A Antitoxin
    Susan E Maslanka
    Centers for Disease Control and Prevention, Atlanta, Georgia
    J Infect Dis 213:379-85. 2016

Collaborators

Detail Information

Publications18

  1. pmc First report worldwide of an infant botulism case due to Clostridium botulinum type E
    Carolina Luquez
    Centers for Disease Control and Prevention, 1600 Clifton Road, MS G 29, Atlanta, GA 30329, USA
    J Clin Microbiol 48:326-8. 2010
    ..Infant botulism type E cases have been associated with neurotoxigenic strains of C. butyricum. We report the first infant botulism case due to C. botulinum type E worldwide...
  2. doi request reprint Molecular subtyping of Clostridium botulinum by pulsed-field gel electrophoresis
    Carolina Luquez
    Enteric Diseases Laboratory Branch, Centers for Disease Control and Prevention, 1600 Clifton Road, MS G 29, Atlanta, GA, 30329, USA
    Methods Mol Biol 1301:103-13. 2015
    ..Here, we describe a standardized laboratory protocol for molecular subtyping of C. botulinum by PFGE...
  3. pmc Genetic diversity among Clostridium botulinum strains harboring bont/A2 and bont/A3 genes
    Carolina Luquez
    Enteric Diseases Laboratory Branch, Centers for Disease Control and Prevention, Atlanta, Georgia, USA
    Appl Environ Microbiol 78:8712-8. 2012
    ..Four groups of strains shared a similarity of at least 95% by PFGE; the largest group included 21 out of 46 strains. The strains analyzed in this study showed relatively limited genetic diversity using either MLST or PFGE...
  4. pmc Characterization of two virulent phages of Lactobacillus plantarum
    Mariángeles Briggiler Marcó
    Instituto de Lactología Industrial UNL CONICET, Facultad de Ingenieria Quimica, Santa Fe, Argentina
    Appl Environ Microbiol 78:8719-34. 2012
    ..Protein analysis revealed 13 (phage B1) and 9 (phage B2) structural proteins. To our knowledge, this is the first report describing such high identity between phage genomes infecting different genera of lactic acid bacteria...
  5. pmc Neurotoxin gene clusters in Clostridium botulinum type Ab strains
    Carolina Luquez
    Enteric Diseases Laboratory Branch, Centers for Disease Control and Prevention, Atlanta, Georgia 30333, USA
    Appl Environ Microbiol 75:6094-101. 2009
    ..The type Ab strains examined in this study had differences in their toxin gene cluster compositions and bont/A and bont/B nucleotide sequences, suggesting that they may have arisen from separate recombination events...
  6. pmc Analysis of a unique Clostridium botulinum strain from the Southern hemisphere producing a novel type E botulinum neurotoxin subtype
    Brian H Raphael
    Centers for Disease Control and Prevention, Atlanta, GA 30329, USA
    BMC Microbiol 12:245. 2012
    ..Previous studies showed that the amino acid sequences of BoNT/E produced by various strains differ by < 6% and that the type E neurotoxin gene cluster inserts into the rarA operon...
  7. doi request reprint Detection and differentiation of Clostridium botulinum type A strains using a focused DNA microarray
    Brian H Raphael
    Enteric Diseases Laboratory Branch, Centers for Disease Control and Prevention, Atlanta, GA 30329, USA
    Mol Cell Probes 24:146-53. 2010
    ..The focused microarray format provides a rapid approach for neurotoxin gene detection and preliminary determination of the relatedness of strains isolated from different sources...
  8. pmc Sequence diversity of genes encoding botulinum neurotoxin type F
    Brian H Raphael
    Centers for Disease Control and Prevention, Atlanta, GA 30329, USA
    Appl Environ Microbiol 76:4805-12. 2010
    ..These results demonstrate that extensive nucleotide diversity exists among genes encoding type F neurotoxins from strains with different phylogenetic backgrounds and from various geographical sources...
  9. pmc Clostridium botulinum strains producing BoNT/F4 or BoNT/F5
    Brian H Raphael
    Centers for Disease Control and Prevention, Atlanta, Georgia, USA
    Appl Environ Microbiol 80:3250-7. 2014
    ..Finally, these data support a role for the mobility of a bont/F5-carrying plasmid among strains of diverse genomic backgrounds. ..
  10. doi request reprint A Novel Botulinum Neurotoxin, Previously Reported as Serotype H, Has a Hybrid-Like Structure With Regions of Similarity to the Structures of Serotypes A and F and Is Neutralized With Serotype A Antitoxin
    Susan E Maslanka
    Centers for Disease Control and Prevention, Atlanta, Georgia
    J Infect Dis 213:379-85. 2016
    ..The toxic effects of this hybrid-like BoNT were completely eliminated by existing serotype A antitoxins, including those contained in multivalent therapeutic antitoxin products that are the mainstay of human botulism treatment. ..
  11. pmc Functional characterization of botulinum neurotoxin serotype H as a hybrid of known serotypes F and A (BoNT F/A)
    Suzanne R Kalb
    Centers for Disease Control and Prevention, National Center for Environmental Health, Division of Laboratory Sciences, 4770 Buford Hwy NE, Atlanta, Georgia 30341, United States
    Anal Chem 87:3911-7. 2015
    ..This work suggests that the newly reported serotype H may actually be a hybrid of previously known BoNT serotype A and serotype F, specifically subtype F5. ..
  12. pmc Genetic homogeneity of Clostridium botulinum type A1 strains with unique toxin gene clusters
    Brian H Raphael
    Enteric Diseases Laboratory Branch, Centers for Disease Control and Prevention, 1600 Clifton Road, Atlanta, GA 30333, USA
    Appl Environ Microbiol 74:4390-7. 2008
    ..These results demonstrate surprising genomic homogeneity among a cluster of unique C. botulinum type A strains of diverse origin...
  13. pmc National outbreak of type a foodborne botulism associated with a widely distributed commercially canned hot dog chili sauce
    Patricia C Juliao
    Enteric Diseases Epidemiology Branch, Centers for Disease Control and Prevention, Atlanta, GA, USA
    Clin Infect Dis 56:376-82. 2013
    ..Foodborne botulism is a rare and sometimes fatal illness caused by consuming foods containing botulinum neurotoxin...
  14. pmc An alternative in vivo method to refine the mouse bioassay for botulinum toxin detection
    Temeri D Wilder-Kofie
    Division of Scientific Resources, National Center for Emerging and Zoonotic Infectious Diseases, Centers for Disease Control and Prevention, Atlanta, Georgia, USA
    Comp Med 61:235-42. 2011
    ..These results suggest that the mouse toe-spread reflex model may be a more humane alternative to the current mouse bioassay for laboratory investigations of botulism...
  15. doi request reprint Laboratory Investigation of the First Case of Botulism Caused by Clostridium butyricum Type E Toxin in the United States
    Janet K Dykes
    Enteric Diseases Laboratory Branch, Centers for Disease Control and Prevention, Atlanta, Georgia, USA
    J Clin Microbiol 53:3363-5. 2015
    ..This investigation demonstrates the importance of extensive microbiological examination of specimens, which resulted in the isolation of this organism. ..
  16. doi request reprint Characterizing the fecal microbiota of infants with botulism
    T Brian Shirey
    Enteric Diseases Laboratory Branch, Centers for Disease Control and Prevention, Atlanta, GA, 30329, USA
    Microbiome 3:54. 2015
    ..To address this uncertainty, we employed 16S rRNA gene profiling to characterize the fecal microbiota in 14 stool samples among laboratory-confirmed and non-confirmed infant botulism cases...
  17. pmc Distinguishing highly-related outbreak-associated Clostridium botulinum type A(B) strains
    Brian H Raphael
    Enteric Diseases Laboratory Branch, Centers for Disease Control and Prevention, Atlanta, GA 30329, USA
    BMC Microbiol 14:192. 2014
    ..botulinum PulseNet database is composed of A(B) strains. The purpose of this study was to evaluate the ability of genome sequencing and multi-loci variable number of tandem repeat analysis (MLVA) to differentiate such strains...
  18. doi request reprint Initial recovery and rebound of type f intestinal colonization botulism after administration of investigational heptavalent botulinum antitoxin
    Ryan P Fagan
    Division of Foodborne, Waterborne, and Environmental Diseases, National Center for Emerging and Zoonotic Infectious Diseases, US Centers for Disease Control and Prevention, Atlanta, Georgia, USA
    Clin Infect Dis 53:e125-8. 2011
    ..Rebound botulism after antitoxin administration is not previously documented but occurred in our patient 10 days after HBAT administration...