Research Topics
| Naomi W LucchiSummaryAffiliation: Centers for Disease Control and Prevention Country: USA Publications
| Collaborators
|
Detail Information
Publications
Molecular diagnosis of malaria by photo-induced electron transfer fluorogenic primers: PET-PCRNaomi W Lucchi
Division of Parasitic Diseases and Malaria, Center for Global Health, Centers for Disease Control and Prevention, Atlanta, Georgia, USA
PLoS ONE 8:e56677. 2013..Further validation of this technique in the field will help to assess its utility for large scale screening in malaria control and elimination programs...
Comparison of molecular tests for the diagnosis of malaria in HondurasGustavo A Fontecha
MEIZ Microbiology School, National Autonomous University of Honduras UNAH, Tegucigalpa, Honduras
Malar J 11:119. 2012..The present study investigated the utility of different molecular tests for the diagnosis of malaria in Honduras...
Real-time fluorescence loop mediated isothermal amplification for the diagnosis of malariaNaomi W Lucchi
Malaria Branch, Division of Parasitic Diseases and Malaria, Center for Global Health, Centers for Disease Control and Prevention, Atlanta, Georgia, United States of America
PLoS ONE 5:e13733. 2010..This tool can provide an alternative to conventional PCR based diagnostic methods for field use in clinical and operational programs...
A new single-step PCR assay for the detection of the zoonotic malaria parasite Plasmodium knowlesiNaomi W Lucchi
Atlanta Research and Education Foundation, Decatur, Georgia, United States of America
PLoS ONE 7:e31848. 2012..knowlesi genomic sequence targets was able to accurately detect P. knowlesi. Additional laboratory and field-based testing of this assay will be necessary to further validate its utility for clinical diagnosis of P. knowlesi...
Real-time loop-mediated isothermal amplification (RealAmp) for the species-specific identification of Plasmodium vivaxJaymin C Patel
Division of Parasitic Diseases and Malaria, Center for Global Health, Centers for Disease Control and Prevention, Atlanta, Georgia, USA
PLoS ONE 8:e54986. 2013..40-100%) compared to the gold standard nested-PCR method. The new primers also proved to be more sensitive than the published species-specific primers specifically developed for the LAMP method in detecting P. vivax...
Potential serological biomarkers of cerebral malariaNaomi W Lucchi
Atlanta Research and Education Foundation, Decatur, GA, USA
Dis Markers 31:327-35. 2011..We propose three main areas in which researchers can attempt to identify CM biomarkers: 1) early biomarkers, 2) diagnostic biomarkers and 3) prognostic biomarkers...
Immunologic activation of human syncytiotrophoblast by Plasmodium falciparumNaomi W Lucchi
Department of Infectious Diseases and Center for Tropical and Emerging Global Diseases, University of Georgia, Athens, GA 30602, USA
Malar J 7:42. 2008..How ST responds to this interaction remains poorly understood. Because it is known that ST is immunoactive and can respond to infectious agents, the consequences of this ST-iRBC interaction should be investigated...
Evaluation of three PCR-based diagnostic assays for detecting mixed Plasmodium infectionTonya Mixson-Hayden
Malaria Branch, Division of Parasitic Diseases, National Center for Zoonotic Vector Borne and Enteric Diseases, Coordinating Center for Infectious Diseases, Centers for Disease Control and Prevention, Atlanta, GA, USA
BMC Res Notes 3:88. 2010..To our knowledge, no one has reported whether the two multiplex methods are better at detecting mixed Plasmodium infections compared to the nested assay using known quantities of DNA in experimentally mixed cocktails...
Macrophage migration inhibitory factor is associated with mortality in cerebral malaria patients in IndiaVidhan Jain
Malaria Branch, Division of Parasitic Diseases, National Center for Zoonotic Vector Borne and Enteric Diseases, Coordinating Center for Infectious Diseases, Centers for Disease Control and Prevention, Atlanta, GA, USA
BMC Res Notes 2:36. 2009..004). CONCLUSION: This study suggests that elevated levels of MIF in the peripheral blood of cerebral malaria patients may be associated with fatal outcomes...
Antibody responses to the merozoite surface protein-1 complex in cerebral malaria patients in IndiaNaomi W Lucchi
Malaria Branch, Division of Parasitic Diseases, National Center for Zoonotic, Vector Borne and Enteric Diseases, Coordinating Center for Infectious Diseases, Centers for Disease Control and Prevention, Atlanta, GA, USA
Malar J 7:121. 2008....
Applied genomics: data mining reveals species-specific malaria diagnostic targets more sensitive than 18S rRNAAllison Demas
Malaria Branch, Division of Parasitic Diseases and Malaria, Center for Global Health, Centers for Disease Control and Prevention, Atlanta, Georgia 30602, USA
J Clin Microbiol 49:2411-8. 2011..These novel targets provide a powerful alternative molecular diagnostic method for the detection of P. falciparum and P. vivax in conventional or multiplex PCR platforms...
Intermittent preventive treatment with sulfadoxine-pyrimethamine against malaria and anemia in pregnant womenNana O Wilson
Department of Microbiology, Biochemistry and Immunology, Morehouse School of Medicine, Atlanta, Georgia 30310, USA
Am J Trop Med Hyg 85:12-21. 2011..18, 95% confidence interval = 0.08-0.37) and anemia (odds ratio = 0.20, 95% confidence interval = 0.12-0.34) remained significant. The recommended IPTp-SP regimen is useful in preventing malaria and anemia among pregnant women in Ghana...
